| scholarly article | Q13442814 |
| review article | Q7318358 |
| P6179 | Dimensions Publication ID | 1038959765 |
| P356 | DOI | 10.1186/S40425-016-0203-4 |
| P932 | PMC publication ID | 5240216 |
| P698 | PubMed publication ID | 28105371 |
| P2093 | author name string | Mohamed E | |
| Cubillos-Ruiz JR | |||
| Rodriguez PC | |||
| P2860 | cites work | Pancreatic beta-cell failure and diabetes in mice with a deletion mutation of the endoplasmic reticulum molecular chaperone gene P58IPK | Q55847305 |
| Execution of Apoptosis Signal-regulating Kinase 1 (ASK1)-induced Apoptosis by the Mitochondria-dependent Caspase Activation | Q57267080 | ||
| Hypoxia stimulates migration of breast cancer cells via the PERK/ATF4/LAMP3-arm of the unfolded protein response | Q22000747 | ||
| Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors | Q22008465 | ||
| Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress | Q22010800 | ||
| Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1 | Q22011167 | ||
| Lipid accumulation and dendritic cell dysfunction in cancer | Q23912213 | ||
| ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs | Q24290776 | ||
| Plasma cell differentiation requires the transcription factor XBP-1 | Q24291453 | ||
| ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats | Q24298956 | ||
| A synthetic biology approach identifies the mammalian UPR RNA ligase RtcB | Q24301555 | ||
| A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells | Q24309442 | ||
| Control of PERK eIF2alpha kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK. | Q24541469 | ||
| The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule | Q24596804 | ||
| Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival | Q24653078 | ||
| Ligand-independent activation of estrogen receptor alpha by XBP-1 | Q24678871 | ||
| Emerging functions of the unfolded protein response in immunity | Q26827965 | ||
| Trial Watch: Immunogenic cell death inducers for anticancer chemotherapy | Q27004011 | ||
| Innate and adaptive immune cells in the tumor microenvironment | Q27008342 | ||
| The unfolded protein response signals through high-order assembly of Ire1 | Q27653139 | ||
| Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (P | Q27681837 | ||
| Tumor progression and the different faces of the PERK kinase | Q28087036 | ||
| Myeloid-derived suppressor cells as regulators of the immune system | Q28131637 | ||
| Dissociation of Kar2p/BiP from an ER sensory molecule, Ire1p, triggers the unfolded protein response in yeast | Q28140422 | ||
| Proteasome inhibitors disrupt the unfolded protein response in myeloma cells | Q28155919 | ||
| IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA | Q28214814 | ||
| Endoplasmic reticulum stress controls M2 macrophage differentiation and foam cell formation | Q28260494 | ||
| ASK1 is essential for JNK/SAPK activation by TRAF2 | Q28285612 | ||
| Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase | Q28296183 | ||
| Oxidized lipids block antigen cross-presentation by dendritic cells in cancer | Q28384581 | ||
| ER stress regulates myeloid-derived suppressor cell fate through TRAIL-R-mediated apoptosis | Q28386923 | ||
| ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis | Q28389316 | ||
| Targeting abnormal ER stress responses in tumors: A new approach to cancer immunotherapy | Q28392706 | ||
| Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies | Q28393381 | ||
| Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
| The transcription factor XBP-1 is essential for the development and survival of dendritic cells | Q28512302 | ||
| Cloning of mammalian Ire1 reveals diversity in the ER stress responses | Q28587224 | ||
| Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response | Q29547299 | ||
| The unfolded protein response: from stress pathway to homeostatic regulation | Q29547396 | ||
| Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress | Q29615495 | ||
| Mediators of endoplasmic reticulum stress-induced apoptosis | Q29615496 | ||
| Translational control in stress and apoptosis | Q29615497 | ||
| Inositol-requiring enzyme 1alpha is a key regulator of angiogenesis and invasion in malignant glioma | Q30496396 | ||
| Inhibition of proliferation by PERK regulates mammary acinar morphogenesis and tumor formation | Q33291107 | ||
| Lectin-type oxidized LDL receptor-1 distinguishes population of human polymorphonuclear myeloid-derived suppressor cells in cancer patients. | Q33564156 | ||
| Mechanism regulating reactive oxygen species in tumor-induced myeloid-derived suppressor cells | Q33707270 | ||
| XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway | Q33926690 | ||
| PERK promotes cancer cell proliferation and tumor growth by limiting oxidative DNA damage | Q33977034 | ||
| Selective inhibition of unfolded protein response induces apoptosis in pancreatic cancer cells. | Q34104084 | ||
| P58IPK, a novel endoplasmic reticulum stress-inducible protein and potential negative regulator of eIF2alpha signaling | Q34179244 | ||
| Endoplasmic reticulum stress-induced transcription factor, CHOP, is crucial for dendritic cell IL-23 expression | Q34199861 | ||
| The stress-response sensor chop regulates the function and accumulation of myeloid-derived suppressor cells in tumors | Q34228171 | ||
| Functional polarization of tumour-associated macrophages by tumour-derived lactic acid. | Q34429912 | ||
| The transcription factor XBP1 is selectively required for eosinophil differentiation | Q34483620 | ||
| Cell-extrinsic effects of tumor ER stress imprint myeloid dendritic cells and impair CD8⁺ T cell priming | Q34525738 | ||
| Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress. | Q34572339 | ||
| Transmission of endoplasmic reticulum stress and pro-inflammation from tumor cells to myeloid cells | Q34836604 | ||
| TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages. | Q35041384 | ||
| Elevated endoplasmic reticulum stress reinforced immunosuppression in the tumor microenvironment via myeloid-derived suppressor cells | Q35067983 | ||
| Endoplasmic reticulum stress in liver disease | Q36031838 | ||
| Endoplasmic Reticulum Stress of Neutrophils Is Required for Ischemia/Reperfusion-Induced Acute Lung Injury | Q36255331 | ||
| miR-211 is a prosurvival microRNA that regulates chop expression in a PERK-dependent manner. | Q36392923 | ||
| Type I interferons mediate pancreatic toxicities of PERK inhibition | Q36394344 | ||
| Protein-folding homeostasis in the endoplasmic reticulum and nutritional regulation | Q36418004 | ||
| The PERK-eIF2α phosphorylation arm is a pro-survival pathway of BCR-ABL signaling and confers resistance to imatinib treatment in chronic myeloid leukemia cells | Q36426519 | ||
| ER stress potentiates insulin resistance through PERK-mediated FOXO phosphorylation | Q36660203 | ||
| Anti-leukemic mechanisms of pegylated arginase I in acute lymphoblastic T-cell leukemia | Q36674887 | ||
| The endoplasmic reticulum stress marker CHOP predicts survival in malignant mesothelioma. | Q36747341 | ||
| HIV protease inhibitor lopinavir-induced TNF-alpha and IL-6 expression is coupled to the unfolded protein response and ERK signaling pathways in macrophages | Q37246875 | ||
| Biphasic, bidirectional regulation of NF-kappaB by endoplasmic reticulum stress | Q37383357 | ||
| Inhibition of tumor progression by suppression of stress protein GRP78/BiP induction in fibrosarcoma B/C10ME. | Q37433487 | ||
| The role of X-box binding protein-1 in tumorigenicity. | Q37553966 | ||
| Abrogation of translation initiation factor eIF-2 phosphorylation causes malignant transformation of NIH 3T3 cells | Q37621199 | ||
| Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2 | Q37622629 | ||
| Molecular pathways: the PERKs and pitfalls of targeting the unfolded protein response in cancer | Q38245607 | ||
| Endoplasmic reticulum stress in immunity | Q38286013 | ||
| Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. | Q38311676 | ||
| The evolving paradigm of cell-nonautonomous UPR-based regulation of immunity by cancer cells | Q38429699 | ||
| Expression of ER stress and autophagy-related molecules in human non-small cell lung cancer and premalignant lesions | Q38470088 | ||
| Endoplasmic reticulum stress-activated cell reprogramming in oncogenesis. | Q38482230 | ||
| The EGFR-specific antibody cetuximab combined with chemotherapy triggers immunogenic cell death. | Q38773904 | ||
| Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response | Q38845249 | ||
| Inhibition of ER stress-associated IRE-1/XBP-1 pathway reduces leukemic cell survival | Q38996766 | ||
| Hypoxic activation of the PERK/eIF2α arm of the unfolded protein response promotes metastasis through induction of LAMP3. | Q39094606 | ||
| IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress. | Q39299575 | ||
| ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth | Q39470144 | ||
| Discovery of GSK2656157: An Optimized PERK Inhibitor Selected for Preclinical Development | Q39781089 | ||
| Integration of Hippo signalling and the unfolded protein response to restrain liver overgrowth and tumorigenesis | Q41392084 | ||
| STAT3 and STAT6 Signaling Pathways Synergize to Promote Cathepsin Secretion from Macrophages via IRE1α Activation | Q41434747 | ||
| Activation of the unfolded protein response is associated with favorable prognosis in acute myeloid leukemia. | Q45995874 | ||
| Characterization of a novel PERK kinase inhibitor with antitumor and antiangiogenic activity | Q46379013 | ||
| Expression and splicing of the unfolded protein response gene XBP-1 are significantly associated with clinical outcome of endocrine-treated breast cancer | Q46665995 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P921 | main subject | endoplasmic reticulum unfolded protein response | Q14633900 |
| activating transcription factor 6 | Q21116808 | ||
| neoplasm | Q1216998 | ||
| endoribonuclease | Q3054027 | ||
| protein-serine-threonine kinases | Q4857068 | ||
| eIF-2 kinase | Q5323131 | ||
| P5008 | on focus list of Wikimedia project | ScienceSource | Q55439927 |
| P304 | page(s) | 5 | |
| P577 | publication date | 2017-01-17 | |
| P1433 | published in | Journal for Immunotherapy of Cancer | Q27725163 |
| P1476 | title | Unfolding anti-tumor immunity: ER stress responses sculpt tolerogenic myeloid cells in cancer | |
| P478 | volume | 5 |
| Q64071978 | ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression |
| Q90441712 | GM2-GM3 gangliosides ratio is dependent on GRP94 through down-regulation of GM2-AP cofactor in brain metastasis cells |
| Q64107945 | Immunogenic Cell Death and Immunotherapy of Multiple Myeloma |
| Q50676824 | Local Activation of p53 in the Tumor Microenvironment Overcomes Immune Suppression and Enhances Antitumor Immunity. |
| Q64065547 | Phenotypic and transcriptomic characterization of canine myeloid-derived suppressor cells |
| Q98771262 | Phyto-Immunotherapy, a Complementary Therapeutic Option to Decrease Metastasis and Attack Breast Cancer Stem Cells |
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