Fibroblasts in cancer (scientific article (publication date: May 2006))

cites work (P2860)

Q42594342	"Scar-cinoma": viewing the fibrotic lung mesenchymal cell in the context of cancer biology.
Q48234869	17β-estradiol and progesterone effect on human papillomavirus 16 positive cells grown as spheroid co-cultures.
Q39385429	22 : 6n-3 DHA inhibits differentiation of prostate fibroblasts into myofibroblasts and tumorigenesis
Q39076663	3D bioprinting: improving in vitro models of metastasis with heterogeneous tumor microenvironments.
Q34512627	3D microchannel co-culture: method and biological validation
Q35994548	3D tumor tissue analogs and their orthotopic implants for understanding tumor-targeting of microenvironment-responsive nanosized chemotherapy and radiation
Q61812763	A Barter Economy in Tumors: Exchanging Metabolites through Gap Junctions
Q39023415	A CCL2/ROS autoregulation loop is critical for cancer-associated fibroblasts-enhanced tumor growth of oral squamous cell carcinoma
Q38738541	A COL11A1-correlated pan-cancer gene signature of activated fibroblasts for the prioritization of therapeutic targets
Q37699961	A Conditioned Medium of Umbilical Cord Mesenchymal Stem Cells Overexpressing Wnt7a Promotes Wound Repair and Regeneration of Hair Follicles in Mice.
Q92769536	A DNA vaccine expressing an optimized secreted FAPα induces enhanced anti-tumor activity by altering the tumor microenvironment in a murine model of breast cancer
Q28544872	A FTIR imaging characterization of fibroblasts stimulated by various breast cancer cell lines
Q42324573	A High-Fat Diet Promotes Mammary Gland Myofibroblast Differentiation through MicroRNA 140 Downregulation
Q47968431	A Multiscale Mathematical Model of Tumour Invasive Growth.
Q58698491	A Paradoxical Correlation of Cancer-Associated Fibroblasts With Survival Outcomes in B-Cell Lymphomas and Carcinomas
Q55289233	A Preclinical Model for the ATLL Lymphoma Subtype With Insights Into the Role of Microenvironment in HTLV-1-Mediated Lymphomagenesis.
Q36786090	A Self-Folding Hydrogel In Vitro Model for Ductal Carcinoma
Q42374110	A Theoretical Model of the Wnt Signaling Pathway in the Epithelial Mesenchymal Transition
Q92034936	A ZEB1/p53 signaling axis in stromal fibroblasts promotes mammary epithelial tumours
Q36175376	A calixpyrrole derivative acts as an antagonist to GPER, a G-protein coupled receptor: mechanisms and models
Q90447760	A comparative study of the frequency of myofibroblasts and macrophages between the oral and cutaneous squamous cell carcinoma
Q41755608	A cross-talk network that facilitates tumor virotherapy
Q37826352	A digest on the role of the tumor microenvironment in gastrointestinal cancers
Q36861021	A fibrotic focus is a prognostic factor and a surrogate marker for hypoxia and (lymph)angiogenesis in breast cancer: review of the literature and proposal on the criteria of evaluation
Q92932998	A framework for advancing our understanding of cancer-associated fibroblasts
Q35206586	A functional in vitro model of heterotypic interactions reveals a role for interferon-positive carcinoma associated fibroblasts in breast cancer.
Q37578778	A gene expression profile for detection of sufficient tumour cells in breast tumour tissue: microarray diagnosis eligibility
Q41470731	A genetic polymorphism repurposes the G-protein coupled and membrane-associated estrogen receptor GPER to a transcription factor-like molecule promoting paracrine signaling between stroma and breast carcinoma cells
Q28731921	A heterogeneous in vitro three dimensional model of tumour-stroma interactions regulating sprouting angiogenesis
Q39089853	A high-throughput-compatible 3D microtissue co-culture system for phenotypic RNAi screening applications
Q88488558	A history of exploring cancer in context
Q61795892	A mathematical-descriptor of tumor-mesoscopic-structure from computed-tomography images annotates prognostic- and molecular-phenotypes of epithelial ovarian cancer
Q38715630	A mechanically active heterotypic E-cadherin/N-cadherin adhesion enables fibroblasts to drive cancer cell invasion
Q27318442	A membrane-type-1 matrix metalloproteinase (MT1-MMP)-discoidin domain receptor 1 axis regulates collagen-induced apoptosis in breast cancer cells
Q30356080	A microfluidic chip for screening individual cancer cells via eavesdropping on autophagy-inducing crosstalk in the stroma niche.
Q47789820	A microfluidic platform for modeling metastatic cancer cell matrix invasion
Q36777149	A multi-antigen vaccine in combination with an immunotoxin targeting tumor-associated fibroblast for treating murine melanoma
Q35811284	A novel 3D high-content assay identifies compounds that prevent fibroblast invasion into tissue surrogates
Q35056258	A novel GFP nude rat model to investigate tumor-stroma interactions
Q36841790	A novel eGFP-expressing immunodeficient mouse model to study tumor-host interactions.
Q51079254	A novel method to generate single-cell-derived cancer-associated fibroblast clones.
Q37316568	A novel organotypic model mimics the tumor microenvironment
Q40437353	A novel regulation of PD-1 ligands on mesenchymal stromal cells through MMP-mediated proteolytic cleavage.
Q35798885	A phenotype from tumor stroma based on the expression of metalloproteases and their inhibitors, associated with prognosis in breast cancer.
Q47679355	A polysaccharide from Dictyophora indusiata inhibits the immunosuppressive function of cancer-associated fibroblasts.
Q61135012	A positive feedback loop bi-stably activates fibroblasts
Q36470281	A potent immunotoxin targeting fibroblast activation protein for treatment of breast cancer in mice
Q35763496	A proteomic analysis of the functional effects of fatty acids in NIH 3T3 fibroblasts
Q39013985	A role for cancer-associated fibroblasts in inducing the epithelial-to-mesenchymal transition in human tongue squamous cell carcinoma
Q52649935	A shift from papillary to reticular fibroblasts enables tumour-stroma interaction and invasion.
Q36867763	A simple way to enhance Doxil® therapy: drug release from liposomes at the tumor site by amphiphilic block copolymer.
Q34143251	A strategy for integrating essential three-dimensional microphysiological systems of human organs for realistic anticancer drug screening.
Q34579646	A systems view of epithelial-mesenchymal transition signaling states
Q33716526	A three-dimensional in vitro model of tumor cell intravasation
Q30449030	A three-dimensional in vitro ovarian cancer coculture model using a high-throughput cell patterning platform
Q38527867	A top-down view of the tumor microenvironment: structure, cells and signaling
Q91168620	ATF3 and JDP2 deficiency in cancer associated fibroblasts promotes tumor growth via SDF-1 transcription
Q42635937	Aberrant DNA methylation in non-small cell lung cancer-associated fibroblasts
Q41459813	Aberrant low expression of p85α in stromal fibroblasts promotes breast cancer cell metastasis through exosome-mediated paracrine Wnt10b
Q37006135	Acidic extracellular pH of tumors induces octamer-binding transcription factor 4 expression in murine fibroblasts in vitro and in vivo
Q36166268	Activatable near-infrared fluorescent probe for in vivo imaging of fibroblast activation protein-alpha
Q58555545	Activated Tumor-infiltrating Fibroblasts Predict Worse Prognosis in Breast Cancer Patients
Q36304689	Activated hepatic stellate cells promote angiogenesis via interleukin-8 in hepatocellular carcinoma
Q45819221	Activated hepatic stellate cells promote hepatocellular carcinoma development in immunocompetent mice
Q39553893	Activation of Notch1 signaling in stromal fibroblasts inhibits melanoma growth by upregulating WISP-1.
Q36243638	Activation of Robo1 signaling of breast cancer cells by Slit2 from stromal fibroblast restrains tumorigenesis via blocking PI3K/Akt/β-catenin pathway
Q37745603	Activation of fibroblasts in cancer stroma
Q45991749	Activation of the HGF/c-Met axis in the tumor microenvironment: A multispecies model.
Q35810840	Active roles of tumor stroma in breast cancer metastasis
Q40310120	Adenovirus i-leader truncation bioselected against cancer-associated fibroblasts to overcome tumor stromal barriers
Q36357889	Adipocyte-derived endotrophin promotes malignant tumor progression
Q38621456	Adrenergic-mediated increases in INHBA drive CAF phenotype and collagens
Q104073598	Advanced co-culture 3D breast cancer model for investigation of fibrosis induced by external stimuli: optimization study
Q26828808	Advances in the formation, use and understanding of multi-cellular spheroids
Q97884627	Advances in the role of exosomal non-coding RNA in the development, diagnosis, and treatment of gastric cancer (Review)
Q37072080	Alginate Sulfates Mitigate Binding Kinetics of Proangiogenic Growth Factors with Receptors toward Revascularization
Q35608687	Allele-specific regulation of FGFR2 expression is cell type-dependent and may increase breast cancer risk through a paracrine stimulus involving FGF10
Q92528551	Alnus Sibirica Extracts Suppress the Expression of Inflammatory Cytokines Induced by Lipopolysaccharides, Tumor Necrosis Factor-α, and Interferon-γ in Human Dermal Fibroblasts
Q35944809	Alpha8 Integrin (Itga8) Signalling Attenuates Chronic Renal Interstitial Fibrosis by Reducing Fibroblast Activation, Not by Interfering with Regulation of Cell Turnover
Q34712100	Altered AIB1 or AIB1Δ3 expression impacts ERα effects on mammary gland stromal and epithelial content
Q39595827	Altered TGF-β signaling in a subpopulation of human stromal cells promotes prostatic carcinogenesis.
Q37949667	Altered angiogenesis in the tumor microenvironment
Q36225128	Altered expression pattern of integrin alphavbeta3 correlates with actin cytoskeleton in primary cultures of human breast cancer
Q33686113	Altered immunohistochemical expression of mast cell tryptase and chymase in the pathogenesis of oral submucous fibrosis and malignant transformation of the overlying epithelium
Q34170350	Alternative strategies for carcinogenicity assessment: an efficient and simplified approach based on in vitro mutagenicity and cell transformation assays.
Q37987563	Alternatives to the carcinogenicity bioassay for toxicity prediction: are we there yet?
Q37741223	Alternatives to the carcinogenicity bioassay: in silico methods, and the in vitro and in vivo mutagenicity assays
Q92308114	Amino Acid-Mediated Metabolism: A New Power to Influence Properties of Stem Cells
Q36187733	An "elite hacker": breast tumors exploit the normal microenvironment program to instruct their progression and biological diversity
Q58691085	An Approach to Visualize the Deformation of the Intermediate Filament Cytoskeleton in Response to Locally Applied Forces
Q47953832	An FGFR inhibitor converts the tumor promoting effect of TGF-β by the induction of fibroblast-associated genes of hepatoma cells
Q24658358	An absence of stromal caveolin-1 expression predicts early tumor recurrence and poor clinical outcome in human breast cancers
Q36369411	An analogy between the evolution of drug resistance in bacterial communities and malignant tissues
Q52949164	An analysis of the role of follicular lymphoma-associated fibroblasts to promote tumor cell viability following drug-induced apoptosis.
Q90647900	An evolving story of the metastatic voyage of ovarian cancer cells: cellular and molecular orchestration of the adipose-rich metastatic microenvironment
Q34919480	An immunocompetent, orthotopic mouse model of epithelial ovarian cancer utilizing tissue engineered tumor cell sheets
Q38097243	An inflammatory vicious cycle: Fibroblasts and immune cell recruitment in cancer
Q33755480	Analysis of Gene Expression Signatures in Cancer-Associated Stroma from Canine Mammary Tumours Reveals Molecular Homology to Human Breast Carcinomas
Q38436627	Analysis of gene expression changes associated with human carcinoma-associated fibroblasts in non-small cell lung carcinoma
Q33567270	Analysis of gene expression in prostate cancer epithelial and interstitial stromal cells using laser capture microdissection
Q83975441	Analysis of stromal gene expression for the identification of prognostic and predictive molecular markers in cancer therapy
Q39559009	Analysis of the paracrine loop between cancer cells and fibroblasts using a microfluidic chip
Q38130312	Angiogenesis inhibitors in cancer therapy: mechanistic perspective on classification and treatment rationales
Q38707625	Angiotensin 1-7 inhibits angiotensin II-stimulated head and neck cancer progression
Q49789215	Angiotensin-converting enzyme inhibitor reduces scar formation by inhibiting both canonical and noncanonical TGF-β1 pathways.
Q88556224	Animal models for studying tumor microenvironment (TME) and resistance to lymphocytic infiltration
Q33770680	Anti-angiogenic therapy for cancer: current progress, unresolved questions and future directions
Q37520300	Anti-metastatic potential of somatostatin analog SOM230: Indirect pharmacological targeting of pancreatic cancer-associated fibroblasts
Q38782807	Anti-tumor effects of DNA vaccine targeting human fibroblast activation protein α by producing specific immune responses and altering tumor microenvironment in the 4T1 murine breast cancer model
Q37860171	Anticancer compounds derived from fungal endophytes: their importance and future challenges
Q42478274	Antifibrotic properties of c-Ski and its regulation of cardiac myofibroblast phenotype and contractility.
Q28240977	Are oncoantigens suitable targets for anti-tumour therapy?
Q38276312	Areca nut exposure increases secretion of tumor-promoting cytokines in gingival fibroblasts that trigger DNA damage in oral keratinocytes.
Q34145927	Arousal of cancer-associated stroma: overexpression of palladin activates fibroblasts to promote tumor invasion
Q59332947	Artemisinin derivatives inactivate cancer-associated fibroblasts through suppressing TGF-β signaling in breast cancer
Q47363573	Assembly of breast cancer heterotypic spheroids on hyaluronic acid coated surfaces.
Q65000145	Assessment of the Spatial Heterogeneity of Breast Cancers: Associations Between Computed Tomography and Immunohistochemistry.
Q37708880	Association between tumor-stroma ratio and prognosis in solid tumor patients: a systematic review and meta-analysis
Q35168174	Association of RB/p16-pathway perturbations with DCIS recurrence: dependence on tumor versus tissue microenvironment
Q50883910	Association of tumor-associated fibroblasts with progression of hepatocellular carcinoma.
Q104478507	Authentic Vascular and Stromal Structure in Animal Disease Model for Nanomedicine
Q42326440	Autocrine IL-1β-TRAF6 signalling promotes squamous cell carcinoma invasion through paracrine TNFα signalling to carcinoma-associated fibroblasts
Q34358613	Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts
Q38720813	Autocrine and Paracrine Mechanisms Promoting Chemoresistance in Cholangiocarcinoma
Q38017624	Autophagic tumor stroma: mechanisms and roles in tumor growth and progression
Q24611183	Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment
Q36585665	Autophagy is required for IL-2-mediated fibroblast growth
Q43602040	Avoiding pitfalls in gene (co)expression meta-analysis
Q34092023	Axitinib Improves Radiotherapy in Murine Xenograft Lung Tumors
Q37102097	Axonal Growth Arrests After an Increased Accumulation of Schwann Cells Expressing Senescence Markers and Stromal Cells in Acellular Nerve Allografts
Q53213846	BMP pathway suppression is an early event in inflammation-driven colon neoplasmatogenesis of uPA-deficient mice.
Q26824827	BMPs and their clinical potentials
Q35875652	Basal Cell Carcinoma in Gorlin's Patients: a Matter of Fibroblasts-Led Protumoral Microenvironment?
Q37082865	Beta-catenin overexpression in Dupuytren's disease is unrelated to disease recurrence
Q91967093	Beyond proteases: Basement membrane mechanics and cancer invasion
Q54993659	Beyond the Biomarker: Understanding the Diverse Roles of Human Epididymis Protein 4 in the Pathogenesis of Epithelial Ovarian Cancer.
Q28066409	Bidirectional interconversion of stem and non-stem cancer cell populations: A reassessment of theoretical models for tumor heterogeneity
Q49232945	Bioinformatics analysis of gene expression alterations conferring drug resistance in tumor samples from melanoma patients with EGFR-activating BRAF mutations.
Q39386471	Bioinspired Hydrogels to Engineer Cancer Microenvironments
Q34663710	Biological characteristics and genetic heterogeneity between carcinoma-associated fibroblasts and their paired normal fibroblasts in human breast cancer
Q91997750	Biological heterogeneity and versatility of cancer-associated fibroblasts in the tumor microenvironment
Q33294142	Biomarker discovery for colon cancer using a 761 gene RT-PCR assay.
Q35414980	Biomarker identification with ligand-targeted nucleoprotein assemblies
Q37209254	Biomarkers for epithelial-mesenchymal transitions
Q92989877	Biomaterials to model and measure epithelial cancers
Q28246964	Biomechanical regulation of blood vessel growth during tissue vascularization
Q50862908	Biomimetic Model of Tumor Microenvironment on Microfluidic Platform.
Q28485304	Biomimetic tumor microenvironment on a microfluidic platform
Q48217663	Bioprinting of biomimetic skin containing melanocytes
Q41704441	Biosilica from Living Diatoms: Investigations on Biocompatibility of Bare and Chemically Modified Thalassiosira weissflogii Silica Shells
Q36229070	Bisphenol A induces gene expression changes and proliferative effects through GPER in breast cancer cells and cancer-associated fibroblasts.
Q34807620	Bone Morphogenetic Proteins stimulate mammary fibroblasts to promote mammary carcinoma cell invasion
Q36516556	Bone marrow and tumour stroma: an intimate relationship
Q38090230	Bone marrow cells as precursors of the tumor stroma
Q30415864	Bone marrow derived "fibrocytes" contribute to tumor proliferation and fibrosis in gastric cancer
Q46895359	Bone marrow fibroblasts parallel multiple myeloma progression in patients and mice: in vitro and in vivo studies.
Q35021021	Bone marrow stromal antigen 2 expressed in cancer cells promotes mammary tumor growth and metastasis.
Q93336018	Bone marrow-derived fibroblasts are a functionally distinct stromal cell population in breast cancer
Q64074414	Bone marrow-derived mesenchymal stem cells promote colorectal cancer progression via CCR5
Q36343778	Bone marrow-derived myofibroblasts are the providers of pro-invasive matrix metalloproteinase 13 in primary tumor
Q35909669	Bone marrow-derived stromal cells are associated with gastric cancer progression
Q36259458	Bone metastasis and the metastatic niche
Q39531184	Bone metastasis in a novel breast cancer mouse model containing human breast and human bone
Q36151249	Borrelia burgdorferi Induces TLR2-Mediated Migration of Activated Dendritic Cells in an Ex Vivo Human Skin Model
Q58734172	Brcal Defective Breast Cancer Cells Induce in vitro Transformation of Cancer Associated Fibroblasts (CAFs) to Metastasis Associated Fibroblasts (MAF)
Q27342933	Breast Cancer Cell Invasion into a Three Dimensional Tumor-Stroma Microenvironment
Q91999106	Breast Cancer Tumor Stroma: Cellular Components, Phenotypic Heterogeneity, Intercellular Communication, Prognostic Implications and Therapeutic Opportunities
Q26772925	Breast Cancer-Associated Fibroblasts: Where We Are and Where We Need to Go
Q37011741	Breast cancer as a systemic disease: a view of metastasis
Q39405444	Breast cancer associated fibroblasts promote MCF-7 invasion in vitro by secretion of HGF.
Q39823181	Breast cancer carcinoma-associated fibroblasts differ from breast fibroblasts in immunological and extracellular matrix regulating pathways.
Q37175709	Breast cancer cell-derived matrix supports vascular morphogenesis
Q28743545	Breast cancer cells induce cancer-associated fibroblasts to secrete hepatocyte growth factor to enhance breast tumorigenesis
Q36985012	Breast cancer progression: insights into multifaceted matrix metalloproteinases.
Q35501726	Breast cancer subtype-specific interactions with the microenvironment dictate mechanisms of invasion
Q38781885	Breast cancer upregulating genes in stromal cells by LINE-1 hypermethylation and micrometastatic detection.
Q33652855	Breast cancer-associated fibroblasts confer AKT1-mediated epigenetic silencing of Cystatin M in epithelial cells
Q38704824	Breast cancer-associated fibroblasts: their roles in tumor initiation, progression and clinical applications
Q36212395	Breast cancer-derived extracellular vesicles stimulate myofibroblast differentiation and pro-angiogenic behavior of adipose stem cells
Q34823658	Breast stromal fibroblasts from histologically normal surgical margins are pro-carcinogenic
Q34759911	Breast tumor microenvironment: proteomics highlights the treatments targeting secretome
Q37072581	Bypassing cellular EGF receptor dependence through epithelial-to-mesenchymal-like transitions
Q38807630	CAF cellular glycolysis: linking cancer cells with the microenvironment
Q36839044	CAF-like state in primary skin fibroblasts with constitutional BRCA1 epimutation sheds new light on tumor suppressor deficiency-related changes in healthy tissue
Q36007881	CCL2 mediates cross-talk between cancer cells and stromal fibroblasts that regulates breast cancer stem cells
Q43055825	CCR1-mediated accumulation of myeloid cells in the liver microenvironment promoting mouse colon cancer metastasis
Q34473048	CD117 expression in fibroblasts-like stromal cells indicates unfavorable clinical outcomes in ovarian carcinoma patients
Q35788370	CD133+ colon cancer cells are more interactive with the tumor microenvironment than CD133- cells
Q35485418	CD14-expressing cancer cells establish the inflammatory and proliferative tumor microenvironment in bladder cancer
Q33891662	CD248 facilitates tumor growth via its cytoplasmic domain.
Q34541032	CD271⁺ subpopulation of pancreatic stellate cells correlates with prognosis of pancreatic cancer and is regulated by interaction with cancer cells
Q24633702	CD36 repression activates a multicellular stromal program shared by high mammographic density and tumor tissues
Q39036931	CD44 expressed on cancer-associated fibroblasts is a functional molecule supporting the stemness and drug resistance of malignant cancer cells in the tumor microenvironment
Q49952398	CD44v6 increases gastric cancer malignant phenotype by modulating adipose stromal cell-mediated ECM remodeling.
Q92715634	CD49b, CD87, and CD95 Are Markers for Activated Cancer-Associated Fibroblasts Whereas CD39 Marks Quiescent Normal Fibroblasts in Murine Tumor Models
Q92738018	COL12A1, a novel potential prognostic factor and therapeutic target in gastric cancer
Q33703810	COX-2 and prostaglandin EP3/EP4 signaling regulate the tumor stromal proangiogenic microenvironment via CXCL12-CXCR4 chemokine systems
Q36715145	COX-2 modulates mammary tumor progression in response to collagen density.
Q38792400	CPAM type 2-derived mesenchymal stem cells: Malignancy risk study in a 14-month-old boy.
Q47303229	CR6-interacting factor 1 inhibits invasiveness by suppressing TGF-β-mediated epithelial-mesenchymal transition in hepatocellular carcinoma
Q48184506	CXCL1 induces senescence of cancer-associated fibroblasts via autocrine loops in oral squamous cell carcinoma
Q38743011	CXCL1-Mediated Interaction of Cancer Cells with Tumor-Associated Macrophages and Cancer-Associated Fibroblasts Promotes Tumor Progression in Human Bladder Cancer
Q38831871	CXCL12/CXCR4 activation by cancer-associated fibroblasts promotes integrin β1 clustering and invasiveness in gastric cancer
Q37344836	CXCR4 and matrix metalloproteinase-1 are elevated in breast carcinoma-associated fibroblasts and in normal mammary fibroblasts exposed to factors secreted by breast cancer cells
Q35111214	Caffeine mediates sustained inactivation of breast cancer-associated myofibroblasts via up-regulation of tumor suppressor genes
Q36234684	Calcium channels and pumps in cancer: changes and consequences
Q37093956	Calreticulin mediates an invasive breast cancer phenotype through the transcriptional dysregulation of p53 and MAPK pathways
Q34077177	Can TIE-2 expressing monocytes represent a novel marker for hepatocellular carcinoma?
Q38795935	Can Targeting Stroma Pave the Way to Enhanced Antitumor Immunity and Immunotherapy of Solid Tumors?
Q35739745	Cancer Associated Fibroblasts in Stage I-IIIA NSCLC: Prognostic Impact and Their Correlations with Tumor Molecular Markers.
Q58101680	Cancer Associated Fibroblasts: Naughty Neighbors That Drive Ovarian Cancer Progression
Q49561501	Cancer Associated Fibroblasts: The Architects of Stroma Remodeling.
Q35933910	Cancer Exosomes as Mediators of Drug Resistance
Q92703787	Cancer Stem Cells and Targeting Strategies
Q39197682	Cancer Stem Cells and Their Microenvironment: Biology and Therapeutic Implications.
Q33806357	Cancer and the tumor microenvironment: a review of an essential relationship
Q42516478	Cancer associated fibroblasts (CAFs) are activated in cutaneous basal cell carcinoma and in the peritumoural skin
Q34309899	Cancer associated fibroblasts and tumor growth: focus on multiple myeloma
Q92565907	Cancer associated fibroblasts are distinguishable from peri-tumor fibroblasts by biological characteristics in TSCC
Q36060343	Cancer associated fibroblasts have phenotypic and functional characteristics similar to the fibrocytes that represent a novel MDSC subset
Q35550041	Cancer associated fibroblasts in hematological malignancies
Q33517133	Cancer associated fibroblasts promote tumor growth and metastasis by modulating the tumor immune microenvironment in a 4T1 murine breast cancer model
Q41614004	Cancer associated fibroblasts: An essential role in the tumor microenvironment
Q37943818	Cancer associated fibroblasts: the dark side of the coin.
Q38835031	Cancer cell invasion driven by extracellular matrix remodeling is dependent on the properties of cancer-associated fibroblasts
Q42250953	Cancer cell migration in 3D tissue: negotiating space by proteolysis and nuclear deformability
Q41636608	Cancer cells remodel themselves and vasculature to overcome the endothelial barrier.
Q37307037	Cancer cells suppress p53 in adjacent fibroblasts
Q92419533	Cancer extracellular vesicles contribute to stromal heterogeneity by inducing chemokines in cancer-associated fibroblasts
Q37058267	Cancer prevention and therapy through the modulation of the tumor microenvironment
Q35008756	Cancer progression by breast tumors with Pit-1-overexpression is blocked by inhibition of metalloproteinase (MMP)-13.
Q34024261	Cancer secretomics reveal pathophysiological pathways in cancer molecular oncology
Q57498153	Cancer stem cells and tumorigenesis
Q38881450	Cancer stem cells: progress and challenges in lung cancer
Q38688878	Cancer-Associated Fibroblasts Share Characteristics and Protumorigenic Activity with Mesenchymal Stromal Cells
Q49788190	Cancer-associated Fibroblast-derived IL-6 Promotes Head and Neck Cancer Progression via the Osteopontin-NF-kappa B Signaling Pathway.
Q92823840	Cancer-associated fibroblast heterogeneity in axillary lymph nodes drives metastases in breast cancer through complementary mechanisms
Q40178500	Cancer-associated fibroblast promote transmigration through endothelial brain cells in three-dimensional in vitro models.
Q37252683	Cancer-associated fibroblast suppresses killing activity of natural killer cells through downregulation of poliovirus receptor (PVR/CD155), a ligand of activating NK receptor
Q38881343	Cancer-associated fibroblast-derived CXCL12 causes tumor progression in adenocarcinoma of the esophagogastric junction
Q48099844	Cancer-associated fibroblast-derived Lumican promotes gastric cancer progression via the integrin β1-FAK signaling pathway.
Q87934636	Cancer-associated fibroblasts affect breast cancer cell gene expression, invasion and angiogenesis
Q39144790	Cancer-associated fibroblasts and M2-polarized macrophages synergize during prostate carcinoma progression
Q34887528	Cancer-associated fibroblasts and their putative role in potentiating the initiation and development of epithelial ovarian cancer
Q33942225	Cancer-associated fibroblasts are positively correlated with metastatic potential of human gastric cancers
Q58709083	Cancer-associated fibroblasts contribute to oral cancer cells proliferation and metastasis via exosome-mediated paracrine miR-34a-5p
Q33939820	Cancer-associated fibroblasts derived from EGFR-TKI-resistant tumors reverse EGFR pathway inhibition by EGFR-TKIs
Q38048249	Cancer-associated fibroblasts drive the progression of metastasis through both paracrine and mechanical pressure on cancer tissue
Q46763062	Cancer-associated fibroblasts enhance metastatic potential of lung cancer cells through IL-6/STAT3 signaling pathway
Q37722149	Cancer-associated fibroblasts enhance pancreatic cancer cell invasion by remodeling the metabolic conversion mechanism
Q42131374	Cancer-associated fibroblasts from NSCLC promote the radioresistance in lung cancer cell lines
Q34718091	Cancer-associated fibroblasts from hepatocellular carcinoma promote malignant cell proliferation by HGF secretion
Q35984652	Cancer-associated fibroblasts from human NSCLC survive ablative doses of radiation but their invasive capacity is reduced
Q35598951	Cancer-associated fibroblasts from lung tumors maintain their immunosuppressive abilities after high-dose irradiation
Q35556542	Cancer-associated fibroblasts in a human HEp-2 established laryngeal xenografted tumor are not derived from cancer cells through epithelial-mesenchymal transition, phenotypically activated but karyotypically normal
Q27022816	Cancer-associated fibroblasts in digestive tumors
Q91691166	Cancer-associated fibroblasts in gastrointestinal cancer
Q26738536	Cancer-associated fibroblasts in hepatocellular carcinoma
Q38568893	Cancer-associated fibroblasts in pancreatic adenocarcinoma
Q64236929	Cancer-associated fibroblasts induce epithelial-mesenchymal transition of bladder cancer cells through paracrine IL-6 signalling
Q37559049	Cancer-associated fibroblasts induce epithelial-mesenchymal transition of breast cancer cells through paracrine TGF-β signalling
Q42377290	Cancer-associated fibroblasts induce metalloprotease-independent cancer cell invasion of the basement membrane
Q42697021	Cancer-associated fibroblasts lead tumor invasion through integrin-β3-dependent fibronectin assembly
Q51370517	Cancer-associated fibroblasts mediated chemoresistance by a FOXO1/TGFβ1 signaling loop in esophageal squamous cell carcinoma.
Q39137387	Cancer-associated fibroblasts modulate growth factor signaling and extracellular matrix remodeling to regulate tumor metastasis
Q30358706	Cancer-associated fibroblasts promote an immunosuppressive microenvironment through the induction and accumulation of protumoral macrophages.
Q38839374	Cancer-associated fibroblasts promote angiogenesis in gastric cancer through galectin-1 expression
Q64058085	Cancer-associated fibroblasts promote cisplatin resistance in bladder cancer cells by increasing IGF-1/ERβ/Bcl-2 signalling
Q47579071	Cancer-associated fibroblasts promote directional cancer cell migration by aligning fibronectin.
Q37295430	Cancer-associated fibroblasts promote non-small cell lung cancer cell invasion by upregulation of glucose-regulated protein 78 (GRP78) expression in an integrated bionic microfluidic device
Q38917416	Cancer-associated fibroblasts promote renal cell carcinoma progression
Q36553208	Cancer-associated fibroblasts promote the progression of endometrial cancer via the SDF-1/CXCR4 axis
Q35763343	Cancer-associated fibroblasts provide a suitable microenvironment for tumor development and progression in oral tongue squamous cancer
Q43639734	Cancer-associated fibroblasts regulate the plasticity of lung cancer stemness via paracrine signalling.
Q93005300	Cancer-associated fibroblasts secrete Wnt2 to promote cancer progression in colorectal cancer
Q60311051	Cancer-associated fibroblasts suppress SOX2-induced dysplasia in a lung squamous cancer coculture
Q37476178	Cancer-associated fibroblasts treated with cisplatin facilitates chemoresistance of lung adenocarcinoma through IL-11/IL-11R/STAT3 signaling pathway
Q91754848	Cancer-associated fibroblasts-heroes or villains?
Q88514840	Cancer-associated fibroblasts-stimulated interleukin-11 promotes metastasis of gastric cancer cells mediated by upregulation of MUC1
Q39399237	Cancer-associated orthotopic myofibroblasts stimulates the motility of gastric carcinoma cells
Q36844475	Cancer-associated stromal fibroblasts promote pancreatic tumor progression
Q41768958	Cancer-stellate cell interactions perpetuate the hypoxia-fibrosis cycle in pancreatic ductal adenocarcinoma
Q34268727	Cancer-stromal cell interaction and tumor angiogenesis in gastric cancer
Q41581107	Cancer-stromal interactions in scirrhous gastric carcinoma
Q43848667	Cancer. Breaching the cancer fortress
Q28728960	Cancer: evolutionary, genetic and epigenetic aspects
Q34948192	Candidate markers that associate with chemotherapy resistance in breast cancer through the study on Taxotere-induced damage to tumor microenvironment and gene expression profiling of carcinoma-associated fibroblasts (CAFs).
Q90483916	Carcinoma and Sarcoma Microenvironment at a Glance: Where We Are
Q35949286	Carcinoma-Associated Fibroblasts Lead the Invasion of Salivary Gland Adenoid Cystic Carcinoma Cells by Creating an Invasive Track
Q37061749	Carcinoma-associated fibroblasts are a promising therapeutic target.
Q37621644	Carcinoma-associated fibroblasts are a rate-limiting determinant for tumour progression.
Q39082233	Carcinoma-associated fibroblasts derive from mesothelial cells via mesothelial-to-mesenchymal transition in peritoneal metastasis.
Q38097963	Carcinoma-associated fibroblasts, its implication in head and neck squamous cell carcinoma: a mini review
Q38086460	Carcinoma-associated fibroblasts: non-neoplastic tumour-promoting mesenchymal cells.
Q28078667	Carcinoma-associated fibroblasts: orchestrating the composition of malignancy
Q43185698	Carcinoma-derived exosomes modify microenvironment
Q33892014	Carcinomas contain a matrix metalloproteinase-resistant isoform of type I collagen exerting selective support to invasion
Q38423895	Cardiac fibroblast physiology and pathology
Q58047168	Cardiac fibroblast to myofibroblast differentiation in vivo and in vitro: Expression of focal adhesion components in neonatal and adult rat ventricular myofibroblasts
Q30467800	Cardiac fibroblast: the renaissance cell
Q43152071	Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling
Q34757218	Cathelicidin suppresses colon cancer development by inhibition of cancer associated fibroblasts
Q33918879	Cathepsin B is the driving force of esophageal cell invasion in a fibroblast-dependent manner
Q37362547	Cathepsin C is a tissue-specific regulator of squamous carcinogenesis.
Q30525290	Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors
Q38164322	Caveolin-1 expression in papillary thyroid carcinoma: correlation with clinicopathological parameters and BRAF mutation status.
Q34634642	Caveolin-1 expression level in cancer associated fibroblasts predicts outcome in gastric cancer
Q35197488	Caveolin-1 is a modulator of fibroblast activation and a potential biomarker for gastric cancer
Q41859040	Cdc42 regulates Cdc42EP3 function in cancer-associated fibroblasts
Q36426917	Cdc42EP3/BORG2 and Septin Network Enables Mechano-transduction and the Emergence of Cancer-Associated Fibroblasts
Q36632955	Cell Competition Drives the Growth of Intestinal Adenomas in Drosophila
Q42829562	Cell behavior observation and gene expression analysis of melanoma associated with stromal fibroblasts in a three-dimensional magnetic cell culture array
Q51429442	Cell migration in microengineered tumor environments.
Q43185634	Cell type specific gene expression analysis of prostate needle biopsies resolves tumor tissue heterogeneity.
Q38134726	Cell volume regulation in epithelial physiology and cancer
Q90354953	Cell-Cell Mechanical Communication in Cancer
Q37858332	Cell-extracellular matrix interactions in normal and diseased skin
Q37205669	Cell-extrinsic consequences of epithelial stress: activation of protumorigenic tissue phenotypes
Q47113309	Cell-to-cell communication: microRNAs as hormones
Q27305106	Cells activated for wound repair have the potential to direct collective invasion of an epithelium
Q51010069	Cellular Constituents of the Prostate Stroma: Key Contributors to Prostate Cancer Progression and Therapy Resistance.
Q33847830	Cellular and molecular phenotypes of proliferating stromal cells from human carcinomas
Q82771749	Cellular changes in the tumor microenvironment of human esophageal squamous cell carcinomas
Q37361381	Cellular dynamics in the muscle satellite cell niche.
Q39026929	Cellular localization, invasion, and turnover are differently influenced by healthy and tumor-derived extracellular matrix
Q30443462	Cellular mechanisms of tissue fibrosis. 1. Common and organ-specific mechanisms associated with tissue fibrosis.
Q38515812	Cellular prognostic markers in hepatocellular carcinoma
Q37045419	Cellular sources of extracellular matrix in hepatic fibrosis
Q64110189	Challenges and opportunities in exosome research-Perspectives from biology, engineering, and cancer therapy
Q39421353	Change in the microenvironment of breast cancer studied by FTIR imaging
Q28079969	Changes in cellular mechanical properties during onset or progression of colorectal cancer
Q41810070	Changes in the Secretory Profile of NSCLC-Associated Fibroblasts after Ablative Radiotherapy: Potential Impact on Angiogenesis and Tumor Growth
Q36376298	Changes in the expression of MMP2, MMP9, and ColIV in stromal cells in oral squamous tongue cell carcinoma: relationships and prognostic implications
Q35463568	Chaperone Hsp47 Drives Malignant Growth and Invasion by Modulating an ECM Gene Network
Q39936131	Characterization and functional role of the stroma compartment in prostate tumors
Q92287200	Characterization and printability of Sodium alginate -Gelatin hydrogel for bioprinting NSCLC co-culture
Q64064640	Characterization of Distinct Populations of Carcinoma-Associated Fibroblasts from Non-Small Cell Lung Carcinoma Reveals a Role for ST8SIA2 in Cancer Cell Invasion
Q52937759	Characterization of Human Dermal Fibroblasts in Fabry Disease.
Q40097264	Characterization of arecoline-induced effects on cytotoxicity in normal human gingival fibroblasts by global gene expression profiling.
Q33935224	Characterization of cancer stem-like cells derived from mouse induced pluripotent stem cells transformed by tumor-derived extracellular vesicles
Q50551197	Characterization of human breast cancer tissues by infrared imaging.
Q84100136	Characterization of the interaction between fibroblasts and tumor cells on a microfluidic co-culture device
Q35948210	Characterization of various cell lines from different ampullary cancer subtypes and cancer associated fibroblast-mediated responses
Q37816561	Chemokines in cancer related inflammation
Q37732119	Chinese herbal medicine suppresses invasion-promoting capacity of cancer-associated fibroblasts in pancreatic cancer
Q58689162	Chronic Hypoxia Emerging as One of the Driving Forces behind Gene Expression and Prognosis of Hepatocellular Carcinoma
Q46489977	Chronic Inflammation in Skin Malignancies
Q39240817	Cigarette smoke condensate promotes pro-tumourigenic stromal-epithelial interactions by suppressing miR-145.
Q98945336	Cinnamaldehyde Treatment of Prostate Cancer-Associated Fibroblasts Prevents Their Inhibitory Effect on T Cells Through Toll-Like Receptor 4
Q52619257	Circulating Tumor Cells: Strategies for Capture, Analyses, and Propagation.
Q37087273	Circulating fibrocytes prepare the lung for cancer metastasis by recruiting Ly-6C+ monocytes via CCL2.
Q93063421	Circulating mir-320a promotes immunosuppressive macrophages M2 phenotype associated with lung cancer risk
Q89486428	Cisplatin-activated PAI-1 secretion in the cancer-associated fibroblasts with paracrine effects promoting esophageal squamous cell carcinoma progression and causing chemoresistance
Q35942961	Cleavage of Type I Collagen by Fibroblast Activation Protein-α Enhances Class A Scavenger Receptor Mediated Macrophage Adhesion
Q55516060	Clinical Implications of Lysyl Oxidase-Like Protein 2 Expression in Pancreatic Cancer.
Q34115941	Clinical Implications of Marker Expression of Carcinoma-Associated Fibroblasts (CAFs) in Patients with Epithelial Ovarian Carcinoma After Treatment with Neoadjuvant Chemotherapy
Q39367207	Clinical and functional significance of loss of caveolin-1 expression in breast cancer-associated fibroblasts
Q37427390	Clinical and translational implications of the caveolin gene family: lessons from mouse models and human genetic disorders
Q65556503	Clinical cancer nanomedicine
Q38184908	Clinical relevance of circulating cell-free microRNAs in cancer
Q45748100	Clinical significance of integrin αvβ6 expression effects on gastric carcinoma invasiveness and progression via cancer-associated fibroblasts
Q46281166	Clonality of smooth muscle and fibroblast cell populations isolated from human fibroid and myometrial tissues.
Q28552528	Co-Culture of Tumor Spheroids and Fibroblasts in a Collagen Matrix-Incorporated Microfluidic Chip Mimics Reciprocal Activation in Solid Tumor Microenvironment
Q41665070	Co-culture with lung cancer A549 cells promotes the proliferation and migration of mesenchymal stem cells derived from bone marrow
Q33716011	Co-delivery of cisplatin and rapamycin for enhanced anticancer therapy through synergistic effects and microenvironment modulation.
Q30485978	Coherent anti-Stokes Raman scattering imaging of lipids in cancer metastasis
Q92194533	Collagen content and extracellular matrix cause cytoskeletal remodelling in pancreatic fibroblasts
Q92239280	Collagen fragments quantified in serum as measures of desmoplasia associate with survival outcome in patients with advanced pancreatic cancer
Q48533249	Collagen triple helix repeat containing 1 promotes tumor angiogenesis in gastrointestinal stromal tumors.
Q55263775	Collagen type 1 promotes survival of human breast cancer cells by overexpressing Kv10.1 potassium and Orai1 calcium channels through DDR1-dependent pathway.
Q64057515	Collagens and Cancer associated fibroblasts in the reactive stroma and its relation to Cancer biology
Q48049656	Collateral Damage Intended-Cancer-Associated Fibroblasts and Vasculature Are Potential Targets in Cancer Therapy.
Q42108626	Collective invasion of carcinoma cells: when the fibroblasts take the lead
Q39057587	Collective migration of cancer-associated fibroblasts is enhanced by overexpression of tight junction-associated proteins claudin-11 and occludin
Q36143306	Color-Coded Imaging of Breast Cancer Metastatic Niche Formation in Nude Mice
Q38652194	Colorectal Cancer Subtypes: Developmental Origin and Microenvironmental Regulation
Q39585082	Colorectal cancer cells activate adjacent fibroblasts resulting in FGF1/FGFR3 signaling and increased invasion
Q64278846	Colorectal cancer, radiotherapy and gut microbiota
Q47968180	Colorectal carcinoma-derived fibroblasts modulate natural killer cell phenotype and antitumor cytotoxicity
Q36600567	Combination of a novel gene expression signature with a clinical nomogram improves the prediction of survival in high-risk bladder cancer.
Q36545800	Combinatorial TGF-β attenuation with paclitaxel inhibits the epithelial-to-mesenchymal transition and breast cancer stem-like cells
Q38556589	Combined Secretomics and Transcriptomics Revealed Cancer-Derived GDF15 is Involved in Diffuse-Type Gastric Cancer Progression and Fibroblast Activation
Q55066611	Comparative assessment of HIF-1α and Akt responses in human lung and skin cells exposed to benzo[α]pyrene: Effect of conditioned medium from pre-exposed primary fibroblasts.
Q90329840	Comparative phenotypic profiling of the JAK2 inhibitors ruxolitinib, fedratinib, momelotinib, and pacritinib reveals distinct mechanistic signatures
Q26851916	Compensatory angiogenesis and tumor refractoriness
Q54662271	Complementary effects of ciclopirox olamine, a prolyl hydroxylase inhibitor and sphingosine 1-phosphate on fibroblasts and endothelial cells in driving capillary sprouting.
Q57821556	Complex formation between platelet-derived growth factor receptor β and transforming growth factor β receptor regulates the differentiation of mesenchymal stem cells into cancer-associated fibroblasts
Q64922761	Comprehensive functional profiling of long non-coding RNAs through a novel pan-cancer integration approach and modular analysis of their protein-coding gene association networks.
Q36771856	Computational selection of antibody-drug conjugate targets for breast cancer.
Q39138664	Concise Review: An (Im)Penetrable Shield: How the Tumor Microenvironment Protects Cancer Stem Cells.
Q36492673	Connective tissue growth factor is overexpressed in human hepatocellular carcinoma and promotes cell invasion and growth
Q57790443	Conophylline suppresses pancreatic cancer desmoplasia and cancer-promoting cytokines produced by cancer-associated fibroblasts
Q35037058	Contribution of bone microenvironment to leukemogenesis and leukemia progression
Q36170766	Control of cyclooxygenase-2 expression and tumorigenesis by endogenous 5-methoxytryptophan.
Q33914878	Controllable Photodynamic Therapy Implemented by Regulating Singlet Oxygen Efficiency
Q42512025	Convergent roles of ATF3 and CSL in chromatin control of cancer-associated fibroblast activation.
Q93088521	Correlation of ultra-high field MRI with histopathology for evaluation of rectal cancer heterogeneity
Q37533025	Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer
Q39104480	Cross-Talk between Cancer Cells and the Tumour Microenvironment: The Role of the 5-Lipoxygenase Pathway.
Q37377875	Cross-species functional analysis of cancer-associated fibroblasts identifies a critical role for CLCF1 and IL-6 in non-small cell lung cancer in vivo.
Q36187740	Crossroads of integrins and cadherins in epithelia and stroma remodeling
Q37338336	Crosstalk between bone marrow-derived myofibroblasts and gastric cancer cells regulates cancer stemness and promotes tumorigenesis
Q60950025	Crosstalk between the Tumor Microenvironment and Immune System in Pancreatic Ductal Adenocarcinoma: Potential Targets for New Therapeutic Approaches
Q36334053	Curcumin inhibits cancer-associated fibroblast-driven prostate cancer invasion through MAOA/mTOR/HIF-1α signaling
Q28543093	Curcumin suppresses crosstalk between colon cancer stem cells and stromal fibroblasts in the tumor microenvironment: potential role of EMT
Q37596833	Curcumin suppresses epithelial-to-mesenchymal transition and metastasis of pancreatic cancer cells by inhibiting cancer-associated fibroblasts
Q36879229	Curcumin triggers p16-dependent senescence in active breast cancer-associated fibroblasts and suppresses their paracrine procarcinogenic effects
Q35742534	Cyclooxygenase-2 blockade can improve efficacy of VEGF-targeting drugs
Q48891850	Cyclophosphamide enhances anti-tumor effects of a fibroblast activation protein α-based DNA vaccine in tumor-bearing mice with murine breast carcinoma.
Q28080901	Cytokines, IBD, and colitis-associated cancer
Q38741833	Cytoplasmic GPER translocation in cancer-associated fibroblasts mediates cAMP/PKA/CREB/glycolytic axis to confer tumor cells with multidrug resistance
Q64108674	Cytoskeletal alteration modulates cancer cell invasion through RhoA-YAP signaling in stromal fibroblasts
Q37153881	DHEA metabolism in prostate: For better or worse?
Q35355691	DNA damage enhanced by the attenuation of SLD5 delays cell cycle restoration in normal cells but not in cancer cells
Q46566715	DNA methylation signal has a major role in the response of human breast cancer cells to the microenvironment.
Q38261602	DNA methylome profiling beyond promoters - taking an epigenetic snapshot of the breast tumor microenvironment
Q35843010	Deciphering mechanisms of drug sensitivity and resistance to Selective Inhibitor of Nuclear Export (SINE) compounds
Q42773442	Decoding information in cell shape
Q47292144	Deconstruction of a metastatic tumor microenvironment reveals a common matrix response in human cancers.
Q45350034	Decreased expression of myosin light chain MYL9 in stroma predicts malignant progression and poor biochemical recurrence-free survival in prostate cancer
Q64069907	Defective Induction of COX-2 Expression by Psoriatic Fibroblasts Promotes Pro-inflammatory Activation of Macrophages
Q55004542	Defining the Role of Solid Stress and Matrix Stiffness in Cancer Cell Proliferation and Metastasis.
Q92689353	Deletion of Calcineurin Promotes a Protumorigenic Fibroblast Phenotype
Q39560761	Deletion of p120-catenin results in a tumor microenvironment with inflammation and cancer that establishes it as a tumor suppressor gene
Q37268993	Depletion of FAP+ cells reduces immunosuppressive cells and improves metabolism and functions CD8+T cells within tumors
Q34269713	Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival
Q37780799	Desmoplasia: not always a bad thing.
Q89538302	Desmoplastic Reaction and Tumor Budding in Cervical Squamous Cell Carcinoma are Prognostic Factors for Distant Metastasis: A Retrospective Study
Q35320642	Detecting high-grade squamous intraepithelial lesions in the cervix with quantitative spectroscopy and per-patient normalization
Q30511926	Detection of MMP-2 and MMP-9 activity in vivo with a triple-helical peptide optical probe
Q34117482	Development and translational imaging of a TP53 porcine tumorigenesis model
Q39909899	Development of tissue-engineered models of oral dysplasia and early invasive oral squamous cell carcinoma.
Q36301365	Diabetic angiopathy and angiogenic defects
Q92442492	Dietary Fucoxanthin Induces Anoikis in Colorectal Adenocarcinoma by Suppressing Integrin Signaling in a Murine Colorectal Cancer Model
Q33498941	Differences in the nemosis response of normal and cancer-associated fibroblasts from patients with oral squamous cell carcinoma
Q84372258	Different gene expression patterns in human papillary and reticular fibroblasts
Q34796473	Differential Inhibition of the TGF-β Signaling Pathway in HCC Cells Using the Small Molecule Inhibitor LY2157299 and the D10 Monoclonal Antibody against TGF-β Receptor Type II.
Q35322827	Differential expression and regulation of vitamin D hydroxylases and inflammatory genes in prostate stroma and epithelium by 1,25-dihydroxyvitamin D in men with prostate cancer and an in vitro model
Q39041457	Differential expression of cancer-associated fibroblast-related proteins according to molecular subtype and stromal histology in breast cancer
Q87401555	Differential expression of miR-139, miR-486 and miR-21 in breast cancer patients sub-classified according to lymph node status
Q91739093	Differentiation and roles of bone marrow-derived cells on the tumor microenvironment of oral squamous cell carcinoma
Q38834166	Diffuse-type gastric cancer cells switch their driver pathways from FGFR2 signaling to SDF1/CXCR4 axis in hypoxic tumor microenvironments
Q26782289	Direct Interaction between Carcinoma Cells and Cancer Associated Fibroblasts for the Regulation of Cancer Invasion
Q34636483	Direct and indirect contribution of bone marrow-derived cells to cancer
Q33871037	Directing the Self-assembly of Tumour Spheroids by Bioprinting Cellular Heterogeneous Models within Alginate/Gelatin Hydrogels
Q92854500	Disabled Homolog 2 (DAB2) Protein in Tumor Microenvironment Correlates with Aggressive Phenotype in Human Urothelial Carcinoma of the Bladder
Q37260920	Discontinuation of anti-VEGF cancer therapy promotes metastasis through a liver revascularization mechanism.
Q36804795	Discovery of endothelium and mesenchymal properties of primo vessels in the mesentery
Q48284400	Dissecting Time- from Tumor-Related Gene Expression Variability in Bilateral Breast Cancer.
Q33265960	Dissection of a metastatic gene expression signature into distinct components
Q36063498	Distinct Transcriptional Changes and Epithelial-Stromal Interactions Are Altered in Early-Stage Colon Cancer Development
Q37269185	Distinct effects of SIRT1 in cancer and stromal cells on tumor promotion
Q34391786	Distinct fibroblast lineages determine dermal architecture in skin development and repair.
Q54403267	Distinct nuclear receptor expression in stroma adjacent to breast tumors.
Q28069801	Distinctive properties of metastasis-initiating cells
Q33916413	Distinctive responsiveness to stromal signaling accompanies histologic grade programming of cancer cells
Q42455372	Distribution of podoplanin-positive tumor vessels predicts disease-specific survival of node-positive breast cancer patients treated with anthracyclines and/or taxanes
Q38181530	Diverse effects of LPA receptors on cell motile activities of cancer cells
Q35228622	Diversity of biological effects induced by longwave UVA rays (UVA1) in reconstructed skin
Q35799412	Down-Regulation of miR-92 in Breast Epithelial Cells and in Normal but Not Tumour Fibroblasts Contributes to Breast Carcinogenesis
Q38779085	Down-regulation of cell adhesion via rho-associated protein kinase (ROCK) pathway promotes tumor cell migration on laminin-511.
Q39939616	Down-regulation of connective tissue growth factor by inhibition of transforming growth factor beta blocks the tumor-stroma cross-talk and tumor progression in hepatocellular carcinoma.
Q34756307	Down-regulation of methylthioadenosine phosphorylase (MTAP) induces progression of hepatocellular carcinoma via accumulation of 5'-deoxy-5'-methylthioadenosine (MTA).
Q39116542	Downregulation of activation factors of endothelia and fibroblasts via lysophosphatidic acid signaling in a mouse lung cancer LL/2 cell line
Q37950977	Drosophila cancer models.
Q47169621	Drug Resistance Driven by Cancer Stem Cells and Their Niche
Q44482658	Dual role of sphingosine kinase-1 in promoting the differentiation of dermal fibroblasts and the dissemination of melanoma cells
Q90903340	Dual role of twist1 in cancer-associated fibroblasts and tumor cells promoted epithelial-mesenchymal transition of esophageal cancer
Q28296046	Ductal carcinoma in situ: terminology, classification, and natural history
Q30596963	Dynamic and influential interaction of cancer cells with normal epithelial cells in 3D culture
Q58577525	Dynamism, Sensitivity, and Consequences of Mesenchymal and Stem-Like Phenotype of Cancer Cells
Q62083308	Dysregulation of Sphingolipid Metabolism in Melanoma: Roles in Pigmentation, Cell Survival and Tumor Progression
Q54380363	E-Cadherin and EpCAM expression by NSCLC tumour cells associate with normal fibroblast activation through a pathway initiated by integrin αvβ6 and maintained through TGFβ signalling.
Q47386263	EB1 and cytoplasmic dynein mediate protrusion dynamics for efficient 3-dimensional cell migration
Q38834075	EGF enhances low-invasive cancer cell invasion by promoting IMP-3 expression
Q82566527	EGRI and FOSB gene expressions in cancer stroma are independent prognostic indicators for epithelial ovarian cancer receiving standard therapy
Q39233875	EMT, CSCs, and drug resistance: the mechanistic link and clinical implications
Q37504554	EMT: when epithelial cells decide to become mesenchymal-like cells
Q34248837	ETV5 cooperates with LPP as a sensor of extracellular signals and promotes EMT in endometrial carcinomas.
Q36970516	Ecological therapy for cancer: defining tumors using an ecosystem paradigm suggests new opportunities for novel cancer treatments
Q33844632	Effect of anatomy on spectroscopic detection of cervical dysplasia
Q61447510	Effect of fibroblast co-culture on the proliferation, viability and drug response of colon cancer cells
Q28651675	Effect of liver regeneration on malignant hepatic tumors
Q34571945	Effect of miR-122 and its target gene cationic amino acid transporter 1 on colorectal liver metastasis
Q33840207	Effect of non-alcoholic liver disease on recurrence rate and liver regeneration after liver resection for colorectal liver metastases
Q36922131	Effector T Cells Abrogate Stroma-Mediated Chemoresistance in Ovarian Cancer
Q52558965	Effects of Neonicotinoid Pesticides on Promoter-Specific Aromatase (CYP19) Expression in Hs578t Breast Cancer Cells and the Role of the VEGF Pathway.
Q41861404	Effects of cancer-associated fibroblasts on the migration and invasion abilities of SGC-7901 gastric cancer cells
Q41612367	Effects of increased Kindlin-2 expression in bladder cancer stromal fibroblasts
Q46269332	Effects of photodynamic therapy on dermal fibroblasts from xeroderma pigmentosum and Gorlin-Goltz syndrome patients
Q96950843	Effects of pirfenidone targeting the tumor microenvironment and tumor-stroma interaction as a novel treatment for non-small cell lung cancer
Q38792108	Effects of radiation on metastasis and tumor cell migration
Q39690173	Effects of small interfering RNAs targeting fascin on human esophageal squamous cell carcinoma cell lines
Q34690943	Egr-1 activation by cancer-derived extracellular vesicles promotes endothelial cell migration via ERK1/2 and JNK signaling pathways
Q38830344	Elastic properties of hydrogels and decellularized tissue sections used in mechanobiology studies probed by atomic force microscopy.
Q36820325	Elastin-elastases and inflamm-aging
Q28551417	Electric Cell-Substrate Impedance Sensing (ECIS) with Microelectrode Arrays for Investigation of Cancer Cell-Fibroblasts Interaction
Q39399018	Elevated expression of angiomodulin (AGM/IGFBP-rP1) in tumor stroma and its roles in fibroblast activation
Q42492498	Elevated expression of chemokine C-C ligand 2 in stroma is associated with recurrent basal-like breast cancers.
Q33954959	Elevated expression of stromal palladin predicts poor clinical outcome in renal cell carcinoma
Q39473591	Elevated progesterone receptor membrane component 1/sigma-2 receptor levels in lung tumors and plasma from lung cancer patients
Q37997493	Emerging evidence of epithelial-to-mesenchymal transition in lung carcinogenesis
Q37584296	Emerging role of mucins in epithelial to mesenchymal transition
Q37141168	Emerging roles of extracellular vesicles in the adaptive response of tumour cells to microenvironmental stress.
Q39611596	Emerging roles of focal adhesion kinase in cancer
Q38008496	Emerging roles of the tumor-associated stroma in promoting tumor metastasis.
Q37376875	Endocrine-immune-paracrine interactions in prostate cells as targeted by phytomedicines
Q55506580	Endogenous Matrix-Derived Inhibitors of Angiogenesis.
Q34988080	Endoglin regulates cancer-stromal cell interactions in prostate tumors
Q89631295	Endothelial Cells in the Tumor Microenvironment
Q64075139	Endothelial cell-derived nidogen-1 inhibits migration of SK-BR-3 breast cancer cells
Q34439455	Endothelial-mesenchymal transition in normal human esophageal endothelial cells cocultured with esophageal adenocarcinoma cells: role of IL-1β and TGF-β2.
Q37129660	Endothelial-stromal interactions in angiogenesis
Q92996743	Endothelial-to-Mesenchymal Transition (EndoMT): Roles in Tumorigenesis, Metastatic Extravasation and Therapy Resistance
Q43697611	Endothelial-to-mesenchymal transition and renal fibrosis in ischaemia/reperfusion injury are mediated by complement anaphylatoxins and Akt pathway
Q95936615	Endothelial-to-mesenchymal transition in anticancer therapy and normal tissue damage
Q54377971	Endothelin-1 stimulates motility of head and neck squamous carcinoma cells by promoting stromal-epithelial interactions.
Q40849132	Energy transfer in "parasitic" cancer metabolism: mitochondria are the powerhouse and Achilles' heel of tumor cells
Q88722501	Engineered microfluidic bioreactor for examining the three-dimensional breast tumor microenvironment
Q89164779	Engineering the pre-metastatic niche
Q34097585	Enhanced paracrine FGF10 expression promotes formation of multifocal prostate adenocarcinoma and an increase in epithelial androgen receptor
Q49132862	Enhancement of fibroblast activation protein α-based vaccines and adenovirus boost immunity by cyclophosphamide through inhibiting IL-10 expression in 4T1 tumor bearing mice.
Q39144705	Enhancement of head and neck squamous cell carcinoma proliferation, invasion, and metastasis by tumor-associated fibroblasts in preclinical models
Q35565766	Enhancement of nab-paclitaxel antitumor activity through addition of multitargeting antiangiogenic agents in experimental pancreatic cancer.
Q36744817	Enhancing sorafenib-mediated sensitization to gemcitabine in experimental pancreatic cancer through EMAP II.
Q38490347	Enrichment map profiling of the cancer invasion front suggests regulation of colorectal cancer progression by the bone morphogenetic protein antagonist, gremlin-1.
Q37786019	Environmental control of invasiveness and metastatic dissemination of tumor cells: the role of tumor cell-host cell interactions.
Q39295109	EphA2-mediated mesenchymal-amoeboid transition induced by endothelial progenitor cells enhances metastatic spread due to cancer-associated fibroblasts
Q38267753	EphA3 biology and cancer.
Q39279690	Epidermal growth factor receptor activation and inhibition in 3D in vitro models of normal skin and human cutaneous squamous cell carcinoma
Q36548726	Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages
Q35578981	Epigenetic silencing of microRNA-149 in cancer-associated fibroblasts mediates prostaglandin E2/interleukin-6 signaling in the tumor microenvironment.
Q36379569	Epigenetic switch drives the conversion of fibroblasts into proinvasive cancer-associated fibroblasts
Q37422742	Epigenomic Deconvolution of Breast Tumors Reveals Metabolic Coupling between Constituent Cell Types
Q34047424	Epithelial and stromal microRNA signatures of columnar cell hyperplasia linking Let-7c to precancerous and cancerous breast cancer cell proliferation
Q92305366	Epithelial-Mesenchymal Plasticity in Organotropism Metastasis and Tumor Immune Escape
Q37846143	Epithelial-mesenchymal interactions in biliary diseases
Q37462579	Epithelial-mesenchymal transition and migration of prostate cancer stem cells is driven by cancer-associated fibroblasts in an HIF-1α/β-catenin-dependent pathway
Q91804158	Epithelial-mesenchymal transition markers screened in a cell-based model and validated in lung adenocarcinoma
Q38024791	Epithelial-mesenchymal transition, the tumor microenvironment, and metastatic behavior of epithelial malignancies.
Q34502015	Epithelial-to-mesenchymal transition in human esophageal cancer associates with tumor progression and patient's survival.
Q37688972	Epithelioid peritoneal mesothelioma: a hybrid phenotype within a mesenchymal-epithelial/epithelial-mesenchymal transition framework
Q89805613	Esophageal Cancer Development: Crucial Clues Arising from the Extracellular Matrix
Q36187837	Esophageal squamous cell carcinoma invasion is inhibited by Activin A in ACVRIB-positive cells
Q26745667	Essential role of miRNAs in orchestrating the biology of the tumor microenvironment
Q61455117	Establishment and Identification of a CiPSC Lineage Reprogrammed from FSP-tdTomato Mouse Embryonic Fibroblasts (MEFs)
Q38793681	Establishment and characterization of a new feline mammary cancer cell line, FkMTp
Q36097586	Establishment of 3D Co-Culture Models from Different Stages of Human Tongue Tumorigenesis: Utility in Understanding Neoplastic Progression
Q41225849	Establishment of a bioluminescence model for microenvironmentally induced oral carcinogenesis with implications for screening bioengineered scaffolds
Q39177165	Establishment of a novel dsRed NOD/Scid mouse strain to investigate the host and tumor cell compartments
Q35099011	Estrogen action and prostate cancer
Q46004480	Estrogen modulates mesenchyme-epidermis interactions in the adult nipple.
Q36140873	Estrogenic gper signaling regulates mir144 expression in cancer cells and cancer-associated fibroblasts (cafs)
Q27309251	Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer
Q34313870	Evaluation of poly-mechanistic antiangiogenic combinations to enhance cytotoxic therapy response in pancreatic cancer
Q33728232	Evaluation of the circulating level of fibroblast activation protein α for diagnosis of esophageal squamous cell carcinoma
Q93045743	Evidence of Tumour Microenvironment and Stromal Cellular Components in Retinoblastoma
Q38735156	Ex vivo culture of circulating tumor cells using magnetic force-based coculture on a fibroblast feeder layer
Q64235554	Exercise promotes a cardioprotective gene program in resident cardiac fibroblasts
Q34171808	Exosomal HIF1α supports invasive potential of nasopharyngeal carcinoma-associated LMP1-positive exosomes
Q90164290	Exosomal MiRNAs in Pediatric Cancers
Q41557851	Exosomal miRNAs and miRNA dysregulation in cancer-associated fibroblasts
Q36528364	Exosomal transfer of functional small RNAs mediates cancer-stroma communication in human endometrium
Q61812643	Exosome-Mediated Signaling in Epithelial to Mesenchymal Transition and Tumor Progression
Q37151539	Exosome-mediated delivery of miR-9 induces cancer-associated fibroblast-like properties in human breast fibroblasts.
Q54959554	Exosomes Released by Gastric Cancer Cells Induce Transition of Pericytes Into Cancer-Associated Fibroblasts.
Q42367399	Exosomes derived from embryonal and alveolar rhabdomyosarcoma carry differential miRNA cargo and promote invasion of recipient fibroblasts
Q33363486	Exosomes from the tumor microenvironment as reciprocal regulators that enhance prostate cancer progression
Q55253817	Exosomes in cancer: small vesicular transporters for cancer progression and metastasis, biomarkers in cancer therapeutics.
Q38091978	Exosomes in tumor microenvironment influence cancer progression and metastasis
Q36028740	Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts
Q47273146	Expansion of patient-derived circulating tumor cells from liquid biopsies using a CTC microfluidic culture device.
Q35581818	Experimental generation of carcinoma-associated fibroblasts (CAFs) from human mammary fibroblasts
Q49859674	Experimental models of pancreatic cancer desmoplasia.
Q35063777	Expression and function of methylthioadenosine phosphorylase in chronic liver disease
Q30491596	Expression of Estrogen and Progesterone Receptor in Tumor Stroma Predicts Favorable Prognosis of Cervical Squamous Cell Carcinoma
Q51123368	Expression of Stromal Caveolin- 1 May Be a Predictor for Aggressive Behaviour of Breast Cancer.
Q83644015	Expression of TREM-1 in hepatic stellate cells and prognostic value in hepatitis B-related hepatocellular carcinoma
Q87774214	Expression of basic fibroblast growth factor, CD31, and α-smooth muscle actin and esophageal cancer recurrence after definitive chemoradiation
Q35713332	Expression of galectin-1 in carcinoma-associated fibroblasts promotes gastric cancer cell invasion through upregulation of integrin β1.
Q47161245	Expression of podoplanin in stromal fibroblasts plays a pivotal role in the prognosis of patients with pancreatic cancer
Q37415468	Expression of the homeobox gene HOXA9 in ovarian cancer induces peritoneal macrophages to acquire an M2 tumor-promoting phenotype.
Q34988742	Expression, tissue distribution and function of miR-21 in esophageal squamous cell carcinoma
Q35667722	Extensive rewiring of epithelial-stromal co-expression networks in breast cancer
Q28304032	Extracellular Hsp90 mediates an NF-κB dependent inflammatory stromal program: implications for the prostate tumor microenvironment
Q91286753	Extracellular Microenvironmental Change by B16F10 Melanoma-derived Proteins Induces Cancer Stem-like Cell Properties from NIH3T3 Cells
Q53541672	Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation.
Q37784711	Extracellular matrix composition reveals complex and dynamic stromal-epithelial interactions in the mammary gland
Q45073825	Extracellular matrix remodeling in 3D: implications in tissue homeostasis and disease progression
Q37189687	Extracellular matrix-induced gene expression in human breast cancer cells
Q38632188	Extracellular matrix-mediated cellular communication in the heart.
Q38307717	Extracellular vesicles as carriers of microRNA, proteins and lipids in tumor microenvironment
Q38238011	Extracellular vesicles as emerging intercellular communicasomes
Q91651363	Extracellular vesicles of carcinoma-associated fibroblasts creates a pre-metastatic niche in the lung through activating fibroblasts
Q38933493	Extracellular vesicles swarm the cancer microenvironment: from tumor-stroma communication to drug intervention.
Q38617934	Extracting Intercellular Signaling Network of Cancer Tissues using Ligand-Receptor Expression Patterns from Whole-tumor and Single-cell Transcriptomes
Q91858448	FAP Delineates Heterogeneous and Functionally Divergent Stromal Cells in Immune-Excluded Breast Tumors
Q31018027	FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and directionality of pancreatic cancer cells
Q36262850	FGF-1/-3/FGFR4 signaling in cancer-associated fibroblasts promotes tumor progression in colon cancer through Erk and MMP-7
Q36785933	FGF10/FGFR2 signal induces cell migration and invasion in pancreatic cancer
Q51592018	FGF2 Overrides TGFβ1-Driven Integrin ITGA11 Expression in Human Dermal Fibroblasts.
Q38644648	FGFR1 is critical for the anti-endothelial mesenchymal transition effect of N-acetyl-seryl-aspartyl-lysyl-proline via induction of the MAP4K4 pathway
Q34760652	FSP1+ fibroblasts promote skin carcinogenesis by maintaining MCP-1-mediated macrophage infiltration and chronic inflammation
Q58799822	FSP1-positive fibroblasts are adipogenic niche and regulate adipose homeostasis
Q37476252	Factors controlling the pharmacokinetics, biodistribution and intratumoral penetration of nanoparticles
Q48763662	Fatty acid binding protein 4 expression in cerebral vascular malformations: implications for vascular remodelling.
Q46633886	Fiber-modified hexon-chimeric oncolytic adenovirus targeting cancer associated fibroblasts inhibits tumor growth in gastric carcinoma
Q64296038	Fibroadhesive scarring of grafted collagen scaffolds interferes with implant-host neural tissue integration and bridging in experimental spinal cord injury
Q98945433	Fibroblast Activation Protein-α Expressing Fibroblasts Promote Lymph Node Metastasis in Esophageal Squamous Cell Carcinoma
Q28728778	Fibroblast EXT1-levels influence tumor cell proliferation and migration in composite spheroids
Q58697838	Fibroblast Growth Factor 10 in Pancreas Development and Pancreatic Cancer
Q35182174	Fibroblast activation protein overexpression and clinical implications in solid tumors: a meta-analysis
Q35754294	Fibroblast activation protein-α, a stromal cell surface protease, shapes key features of cancer associated fibroblasts through proteome and degradome alterations
Q35761855	Fibroblast activation protein-α-expressing fibroblasts promote the progression of pancreatic ductal adenocarcinoma
Q36729100	Fibroblast differentiation in wound healing and fibrosis
Q33964324	Fibroblast heterogeneity in the cancer wound
Q50424157	Fibroblast heterogeneity: implications for human disease.
Q37179409	Fibroblast independency in tumors: implications in cancer therapy
Q39771894	Fibroblast nemosis induces angiogenic responses of endothelial cells
Q36582035	Fibroblast sources: Where can we get them?
Q38771074	Fibroblast spheroids as a model to study sustained fibroblast quiescence and their crosstalk with tumor cells
Q35987339	Fibroblast surface-associated FGF-2 promotes contact-dependent colorectal cancer cell migration and invasion through FGFR-SRC signaling and integrin αvβ5-mediated adhesion
Q41151245	Fibroblast-Extracellular Matrix Interactions in Tissue Fibrosis
Q36917756	Fibroblast-Mediated Collagen Remodeling Within the Tumor Microenvironment Facilitates Progression of Thyroid Cancers Driven by BrafV600E and Pten Loss
Q92163289	Fibroblast-Mediated Immunoregulation of Macrophage Function Is Maintained after Irradiation
Q42475774	Fibroblast-activation protein: a single marker that confidently differentiates morpheaform/infiltrative basal cell carcinoma from desmoplastic trichoepithelioma
Q48102897	Fibroblast-associated tumour microenvironment induces vascular structure-networked tumouroid
Q35167289	Fibroblast-endothelial partners for vascularization strategies in tissue engineering
Q33934433	Fibroblast-secreted hepatocyte growth factor plays a functional role in esophageal squamous cell carcinoma invasion
Q34471885	Fibroblast-specific protein 1 identifies an inflammatory subpopulation of macrophages in the liver
Q26866509	Fibroblasts and myofibroblasts in wound healing
Q64981236	Fibroblasts as Modulators of Local and Systemic Cancer Metabolism.
Q64893292	Fibroblasts as a practical alternative to mesenchymal stem cells.
Q37178453	Fibroblasts as architects of cancer pathogenesis
Q39097256	Fibroblasts as maestros orchestrating tissue regeneration
Q36983715	Fibroblasts as novel therapeutic targets in chronic inflammation
Q40994644	Fibroblasts drive an immunosuppressive and growth-promoting microenvironment in breast cancer via secretion of Chitinase 3-like 1.
Q26998508	Fibroblasts in fibrosis: novel roles and mediators
Q53279967	Fibroblasts in omentum activated by tumor cells promote ovarian cancer growth, adhesion and invasiveness.
Q89631276	Fibroblasts in the Tumor Microenvironment
Q55324986	Fibroblasts in the Tumor Microenvironment: Shield or Spear?
Q38946666	Fibroblasts induce expression of FGF4 in ovarian cancer stem-like cells/cancer-initiating cells and upregulate their tumor initiation capacity
Q34164261	Fibroblasts protect melanoma cells from the cytotoxic effects of doxorubicin.
Q51888402	Fibroblasts share mesenchymal phenotypes with stem cells, but lack their differentiation and colony-forming potential.
Q37543703	Fibroblasts-a diverse population at the center of it all.
Q26768515	Fibronectin Mechanobiology Regulates Tumorigenesis
Q42150675	Fibronectin and beta-catenin act in a regulatory loop in dermal fibroblasts to modulate cutaneous healing
Q36944869	Fibronectin conformation regulates the proangiogenic capability of tumor-associated adipogenic stromal cells
Q30835803	Fibronectin-guided migration of carcinoma collectives
Q33865082	Fibrosis-dependent mechanisms of hepatocarcinogenesis
Q37678004	Fibrotic extracellular matrix activates a profibrotic positive feedback loop
Q91599505	Fibulin-2 is required for basement membrane integrity of mammary epithelium
Q38579572	Flow-induced stress on adherent cells in microfluidic devices
Q34162432	Focal adhesion assembly in myofibroblasts fosters a microenvironment that promotes tumor growth
Q38958706	Focal adhesion kinase knockdown in carcinoma-associated fibroblasts inhibits oral squamous cell carcinoma metastasis via downregulating MCP-1/CCL2 expression
Q85886839	Forkhead box P3 regulatory T cells coexisting with cancer associated fibroblasts are correlated with a poor outcome in lung adenocarcinoma
Q50351390	From Chemotherapy to Combined Targeted Therapeutics: In Vitro and in Vivo Models to Decipher Intra-tumor Heterogeneity.
Q39252748	From inflammation to gastric cancer - the importance of Hedgehog/GLI signaling in Helicobacter pylori-induced chronic inflammatory and neoplastic diseases
Q38045235	From sentinel cells to inflammatory culprits: cancer-associated fibroblasts in tumour-related inflammation
Q46214350	From transformation to metastasis: deconstructing the extracellular matrix in breast cancer
Q85489649	Functional abnormalities and changes in gene expression in fibroblasts and macrophages from the bone marrow of patients with acute myeloid leukemia
Q39535994	Functional characterization of cancer-associated fibroblasts of human cutaneous squamous cell carcinoma
Q34034676	Functional heterogeneity of breast fibroblasts is defined by a prostaglandin secretory phenotype that promotes expansion of cancer-stem like cells
Q28486232	Functional investigation of NCI-H460-inducible myofibroblasts on the chemoresistance to VP-16 with a microfluidic 3D co-culture device
Q42252395	Fusion between cancer cells and myofibroblasts is involved in osteosarcoma
Q36481702	G protein-coupled estrogen receptor mediates the up-regulation of fatty acid synthase induced by 17β-estradiol in cancer cells and cancer-associated fibroblasts
Q37824814	G protein-coupled receptors: novel targets for drug discovery in cancer
Q38818348	GPER Mediates Non-Genomic Effects of Estrogen
Q39432208	GPER mediates the Egr-1 expression induced by 17β-estradiol and 4-hydroxitamoxifen in breast and endometrial cancer cells.
Q27322202	GPER signalling in both cancer-associated fibroblasts and breast cancer cells mediates a feedforward IL1β/IL1R1 response.
Q38762482	GPER, IGF-IR, and EGFR transduction signaling are involved in stimulatory effects of zinc in breast cancer cells and cancer-associated fibroblasts.
Q61804215	GSK-3β regulates the endothelial-to-mesenchymal transition via reciprocal crosstalk between NSCLC cells and HUVECs in multicellular tumor spheroid models
Q36885727	GT198 Expression Defines Mutant Tumor Stroma in Human Breast Cancer.
Q36879539	Galectin-1 mediates TGF-β-induced transformation from normal fibroblasts into carcinoma-associated fibroblasts and promotes tumor progression in gastric cancer
Q39039136	Ganglioside GD3 induces convergence and synergism of adhesion and hepatocyte growth factor/Met signals in melanomas
Q64891812	Gastric carcinogenesis.
Q37631370	Gastrin, inflammation, and carcinogenesis
Q35654127	Gastrointestinal Fibroblasts Have Specialized, Diverse Transcriptional Phenotypes: A Comprehensive Gene Expression Analysis of Human Fibroblasts
Q40539463	Gene expression profile in the activation of subperitoneal fibroblasts reflects prognosis of patients with colon cancer
Q38836952	Gene expression profile of normal and cancer-associated fibroblasts according to intratumoral inflammatory cells phenotype from breast cancer tissue
Q38480261	Gene set enrichment analysis of the NF-κB/Snail/YY1/RKIP circuitry in multiple myeloma.
Q92331139	Gene signature characteristic of elevated stromal infiltration and activation is associated with increased risk of hematogenous and lymphatic metastasis in serous ovarian cancer
Q33699188	Gene targeting to the stroma of the prostate and bone
Q37493634	Generation of iPSC lines from archived non-cryoprotected biobanked dura mater.
Q38115617	Genetic regulation and potentially therapeutic application of cancer-associated fibroblasts in oral cancer.
Q28079323	Genetically engineered mouse models in oncology research and cancer medicine
Q41211788	Genomic deregulation during metastasis of renal cell carcinoma implements a myofibroblast-like program of gene expression.
Q35684810	Genomic differences distinguish the myofibroblast phenotype of distal lung fibroblasts from airway fibroblasts.
Q33895270	Genomics and proteomics approaches to the study of cancer-stroma interactions
Q59134092	Glioblastoma Chemoresistance: The Double Play by Microenvironment and Blood-Brain Barrier
Q37284365	Global analysis of the medulloblastoma epigenome identifies disease-subgroup-specific inactivation of COL1A2
Q35923493	Glycogen synthase kinase-3 inhibition attenuates fibroblast activation and development of fibrosis following renal ischemia-reperfusion in mice
Q38077593	Glycosaminoglycans are functional ligands for receptor for advanced glycation end-products in tumors.
Q57817200	Gold nanoparticles enhance cisplatin delivery and potentiate chemotherapy by decompressing colorectal cancer vessels
Q38605933	Growth-induced stress enhances epithelial-mesenchymal transition induced by IL-6 in clear cell renal cell carcinoma via the Akt/GSK-3β/β-catenin signaling pathway
Q58695521	HGF-mediated crosstalk between cancer-associated fibroblasts and MET-unamplified gastric cancer cells activates coordinated tumorigenesis and metastasis
Q37690722	HIF-1α/GPER signaling mediates the expression of VEGF induced by hypoxia in breast cancer associated fibroblasts (CAFs)
Q36290268	HOXA9 promotes ovarian cancer growth by stimulating cancer-associated fibroblasts.
Q22252312	Hallmarks of Cancer: The Next Generation
Q37704659	Hallmarks of cancer: interactions with the tumor stroma.
Q40408326	Halting pro-survival autophagy by TGFβ inhibition in bone marrow fibroblasts overcomes bortezomib resistance in multiple myeloma patients.
Q37314509	Harnessing competing endocytic pathways for overcoming the tumor-blood barrier: magnetic resonance imaging and near-infrared imaging of bifunctional contrast media
Q60923365	Helicobacter pylori Infection-Induced Hepatoma-Derived Growth Factor Regulates the Differentiation of Human Mesenchymal Stem Cells to Myofibroblast-Like Cells
Q64905339	Hematological Malignancy-Derived Small Extracellular Vesicles and Tumor Microenvironment: The Art of Turning Foes into Friends.
Q55192426	Hematopoietic Stem Cells as a Novel Source of Dental Tissue Cells.
Q38826311	Hepatic carcinoma-associated fibroblasts promote an adaptative response in colorectal cancer cells that inhibit proliferation and apoptosis: nonresistant cells die by nonapoptotic cell death
Q53581215	Hepatic fibrosis 2006: report of the Third AASLD Single Topic Conference.
Q54636179	Hepatic stellate cells accelerate the malignant behavior of cholangiocarcinoma cells.
Q37869041	Hepatic stellate cells: partners in crime for liver metastases?
Q35728873	Hepatitis C virus infection: establishment of chronicity and liver disease progression
Q26781273	Hepatocyte Growth Factor from a Clinical Perspective: A Pancreatic Cancer Challenge
Q54484191	Hepatocyte growth factor in the neighborhood reverses resistance to BRAF inhibitor in melanoma.
Q38655547	Heterocellular cadherin connections: coordinating adhesive cues in homeostasis and cancer
Q36165598	Heterogeneity of Cancer Stem Cells: Rationale for Targeting the Stem Cell Niche
Q33753945	Heterogeneity of gene expression in stromal fibroblasts of human breast carcinomas and normal breast
Q38900718	Heterogeneous tumor stromal microenvironments of oral squamous cell carcinoma cells in tongue and nodal metastatic lesions in a xenograft mouse model
Q39496485	Heterogenous induction of carcinoma-associated fibroblast-like differentiation in normal human prostatic fibroblasts by co-culturing with prostate cancer cells
Q33268351	Heterologous tissue culture expression signature predicts human breast cancer prognosis
Q51135550	Heterotypic 3D tumor culture in a reusable platform using pneumatic microfluidics.
Q37559209	Heterotypic cellular interactions in the ovarian tumor microenvironment: biological significance and therapeutic implications
Q40453995	Hic-5 remodeling of the stromal matrix promotes breast tumor progression.
Q38116862	Hidden keys in stroma: Unlocking the tumor progression.
Q36838871	Hierarchical paracrine interaction of breast cancer associated fibroblasts with cancer cells via hMAPK-microRNAs to drive ER-negative breast cancer phenotype
Q38981271	High Mobility Group Box1 (HMGB1) released from cancer cells induces the expression of pro-inflammatory cytokines in peritoneal fibroblasts
Q39034242	High expression of IGFBP7 in fibroblasts induced by colorectal cancer cells is co-regulated by TGF-β and Wnt signaling in a Smad2/3-Dvl2/3-dependent manner
Q36504170	High levels of EGFR expression in tumor stroma are associated with aggressive clinical features in epithelial ovarian cancer
Q24569637	High levels of microRNA-21 in the stroma of colorectal cancers predict short disease-free survival in stage II colon cancer patients
Q35830253	High-Throughput Cancer Cell Sphere Formation for Characterizing the Efficacy of Photo Dynamic Therapy in 3D Cell Cultures
Q42823539	High-throughput live-cell imaging reveals differential inhibition of tumor cell proliferation by human fibroblasts
Q36223509	Higher heat shock factor 1 expression in tumor stroma predicts poor prognosis in esophageal squamous cell carcinoma patients
Q33392443	Highly variable response to cytotoxic chemotherapy in carcinoma-associated fibroblasts (CAFs) from lung and breast
Q84230455	Histochemical localization of caldesmon isoforms in colon adenocarcinoma and lymph node metastases
Q89450261	Histone deacetylase 6 regulates the immunosuppressive properties of cancer-associated fibroblasts in breast cancer through the STAT3-COX2-dependent pathway
Q37745937	Histone deacetylase inhibitors provoke a tumor supportive phenotype in pancreatic cancer associated fibroblasts
Q55401527	Hodgkin Lymphoma-Derived Extracellular Vesicles Change the Secretome of Fibroblasts Toward a CAF Phenotype.
Q37610824	How cancer cells dictate their microenvironment: present roles of extracellular vesicles
Q91973843	How the ageing microenvironment influences tumour progression
Q52668325	How to Hit Mesenchymal Stromal Cells and Make the Tumor Microenvironment Immunostimulant Rather Than Immunosuppressive.
Q30838920	Hsp90 regulation of fibroblast activation in pulmonary fibrosis
Q39599360	HuR keeps an angiogenic switch on by stabilising mRNA of VEGF and COX-2 in tumour endothelium
Q41082417	Human MSCs promotes colorectal cancer epithelial-mesenchymal transition and progression via CCL5/β-catenin/Slug pathway
Q33790023	Human Peritoneal Mesothelial Cell Death Induced by High-Glucose Hypertonic Solution Involves Ca2+ and Na+ Ions and Oxidative Stress with the Participation of PKC/NOX2 and PI3K/Akt Pathways
Q33665522	Human mammary fibroblasts stimulate invasion of breast cancer cells in a three-dimensional culture and increase stroma development in mouse xenografts
Q24642524	Human periostin gene expression in normal tissues, tumors and melanoma: evidences for periostin production by both stromal and melanoma cells
Q30431576	Human prostate fibroblasts induce growth and confer castration resistance and metastatic potential in LNCaP Cells
Q38811094	Human proximal tubule cells form functional microtissues
Q36394731	Human scaphoid non-unions exhibit increased osteoclast activity compared to adjacent cancellous bone
Q35088390	Human subperitoneal fibroblast and cancer cell interaction creates microenvironment that enhances tumor progression and metastasis
Q34519881	Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice
Q55065517	Hyaluronan, Cancer-Associated Fibroblasts and the Tumor Microenvironment in Malignant Progression.
Q33848539	Hydroxytyrosol inhibits chemokine C-C motif ligand 5 mediated aged quiescent fibroblast-induced stimulation of breast cancer cell proliferation
Q35781386	Hyperproduction of hyaluronan in neu-induced mammary tumor accelerates angiogenesis through stromal cell recruitment: possible involvement of versican/PG-M.
Q47286024	Hypoxia Inducible Factors Modify Collagen I Fibers in MDA-MB-231 Triple Negative Breast Cancer Xenografts
Q49725890	Hypoxia Pathway Proteins As Central Mediators of Metabolism in the Tumor Cells and Their Microenvironment.
Q34820282	Hypoxia and the extracellular matrix: drivers of tumour metastasis
Q36001832	Hypoxia-Induced Changes in DNA Methylation Alter RASAL1 and TGFβ1 Expression in Human Trabecular Meshwork Cells.
Q37294778	Hypoxia-dependent modification of collagen networks promotes sarcoma metastasis.
Q41678975	Hypoxia-inducible factors: a central link between inflammation and cancer
Q63364695	Hypoxic cancer–associated fibroblasts increase NCBP2-AS2/HIAR to promote endothelial sprouting through enhanced VEGF signaling
Q36384120	IKKβ in intestinal mesenchymal cells promotes initiation of colitis-associated cancer
Q36740894	IKKβ/NFκBp65 activated by interleukin-13 targets the autophagy-related genes LC3B and beclin 1 in fibroblasts co-cultured with breast cancer cells
Q38982850	IL-6 enriched lung cancer stem-like cell population by inhibition of cell cycle regulators via DNMT1 upregulation
Q33591332	IL-6 secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and metastasis of gastric cancer via JAK2/STAT3 signaling pathway
Q30422218	IQGAP1 suppresses TβRII-mediated myofibroblastic activation and metastatic growth in liver
Q39396200	Identification of CXCL5/ENA-78 as a factor involved in the interaction between cholangiocarcinoma cells and cancer-associated fibroblasts
Q33706243	Identification of E-selectin as a novel target for the regulation of postnatal neovascularization: implications for diabetic wound healing
Q92217667	Identification of Pparγ-modulated miRNA hubs that target the fibrotic tumor microenvironment
Q91708327	Identification of a Tumor Microenvironment-Related Eight-Gene Signature for Predicting Prognosis in Lower-Grade Gliomas
Q33924416	Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis.
Q33446102	Identification of multipotent mesenchymal stromal cells in the reactive stroma of a prostate cancer xenograft by side population analysis
Q98158929	Identification of prognosis-related genes and construction of multi-regulatory networks in pancreatic cancer microenvironment by bioinformatics analysis
Q38836443	Identification of tumour-reactive lymphatic endothelial cells capable of inducing progression of gastric cancer
Q64964306	Identification of two molecular subtypes in canine mast cell tumours through gene expression profiling.
Q41856522	Identifying common genes and networks in multi-organ fibrosis
Q58214748	Idiopathic Pulmonary Fibrosis Is Associated With Endothelial To Mesenchymal Transition
Q36850133	Imaging Extracellular Matrix Remodeling In Vitro by Diffusion-Sensitive Optical Coherence Tomography
Q44680217	Imaging the recruitment of cancer-associated fibroblasts by liver-metastatic colon cancer
Q34339761	Immortalized tumor derived rat fibroblasts as feeder cells facilitate the cultivation of male embryonic stem cells from the rat strain WKY/Ztm
Q50217783	Immune Cell Metabolism in Tumor Microenvironment.
Q50883844	Immunization of stromal cell targeting fibroblast activation protein providing immunotherapy to breast cancer mouse model.
Q40009177	Immunohistochemical evidence for Zic1 coexpression with beta-catenin in the myofibroblast of Dupuytren disease
Q34165529	Immunohistochemical expression of epithelial and stromal immunomodulatory signalling molecules is a prognostic indicator in breast cancer
Q38608340	Immunological hallmarks of stromal cells in the tumour microenvironment
Q37974937	Immunology in the clinic review series; focus on cancer: tumour-associated macrophages: undisputed stars of the inflammatory tumour microenvironment
Q38407555	Immunopathogenesis of Myocarditis: The Interplay Between Cardiac Fibroblast Cells, Dendritic Cells, Macrophages and CD4+ T Cells
Q49592831	Immunotherapeutic Targeting of Tumor-Associated Blood Vessels.
Q54467130	Immunotherapy of tumor with vaccine based on basic fibroblast growth factor-activated fibroblasts.
Q93048666	Impact of Cancer-Associated Fibroblast on the Radiation-Response of Solid Xenograft Tumors
Q47714743	Impact of Her-2 Overexpression on Survival of Patients with Metastatic Breast Cancer
Q42281477	Impact of the prolymphangiogenic crosstalk in the tumor microenvironment on lymphatic cancer metastasis.
Q92030460	Importance of the immune system in head and neck cancer
Q30759342	In Vivo Visualization and Characterization of Epithelial-Mesenchymal Transition in Breast Tumors
Q33715089	In silico and Ex vivo approaches identify a role for toll-like receptor 4 in colorectal cancer
Q34137584	In silico models of cancer
Q30576475	In vitro cell transformation assays for an integrated, alternative assessment of carcinogenicity: a data-based analysis
Q30583218	In vivo imaging of the systemic recruitment of fibroblasts to the angiogenic rim of ovarian carcinoma tumors
Q39340605	Inactivation of Rb in stromal fibroblasts promotes epithelial cell invasion.
Q33560776	Increased KIT inhibition enhances therapeutic efficacy in gastrointestinal stromal tumor
Q44002372	Increased androgen receptor and remodeling in the prostatic stroma after the inhibition of 5-alpha reductase and aromatase in gerbil ventral prostate.
Q34050895	Increased expression of CCN2, epithelial membrane antigen, and fibroblast activation protein in hepatocellular carcinoma with fibrous stroma showing aggressive behavior
Q35225647	Increased expression of chemerin in squamous esophageal cancer myofibroblasts and role in recruitment of mesenchymal stromal cells
Q43128717	Induction and progression of cholangiofibrosis in rat liver injured by oral administration of furan
Q28396847	Induction of cancer-associated fibroblast-like cells by carbon nanotubes dictates its tumorigenicity
Q46103260	Induction of phenotype modifying cytokines by FERMT1 mutations.
Q30674996	Inferring tumour purity and stromal and immune cell admixture from expression data
Q37956599	Inflamm-aging of the stem cell niche: breast cancer as a paradigmatic example: breakdown of the multi-shell cytokine network fuels cancer in aged people
Q33704284	Inflammation and Epithelial-Mesenchymal Transition in Pancreatic Ductal Adenocarcinoma: Fighting Against Multiple Opponents
Q38921024	Inflammatory Chemokines MIP-1δ and MIP-3α Are Involved in the Migration of Multipotent Mesenchymal Stromal Cells Induced by Hepatoma Cells
Q36352894	Inflammatory Gene Expression Upon TGF-β1-Induced p38 Activation in Primary Dupuytren's Disease Fibroblasts.
Q42124513	Inflammatory alterations of the extracellular matrix in the tumor microenvironment
Q38412911	Inflammatory fibroblasts in cancer
Q38238739	Inflammatory pathways in the early steps of colorectal cancer development.
Q51818212	Influence of microenvironment topography and stiffness on the mechanics and motility of normal and cancer renal cells.
Q39587564	Influence of stromal-epithelial interactions on breast cancer in vitro and in vivo
Q39273621	Infrared imaging in breast cancer: automated tissue component recognition and spectral characterization of breast cancer cells as well as the tumor microenvironment
Q35369888	Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma
Q41173608	Inhibition of Bone Marrow-Derived Mesenchymal Stem Cells Homing Towards Triple-Negative Breast Cancer Microenvironment Using an Anti-PDGFRβ Aptamer.
Q42214252	Inhibition of CXCLs/CXCR2 axis in the tumor microenvironment might be a potent therapeutics for pancreatic cancer
Q37327720	Inhibition of cancer cell epithelial mesenchymal transition by normal fibroblasts via production of 5-methoxytryptophan
Q38597208	Inhibition of discoidin domain receptor 1 reduces collagen-mediated tumorigenicity in pancreatic ductal adenocarcinoma.
Q39816968	Inhibition of pro-HGF activation by SRI31215, a novel approach to block oncogenic HGF/MET signaling
Q36250217	Inhibition of stromal CXCR4 impairs development of lung metastases.
Q39000276	Inhibition of transforming growth factor-β signaling potentiates tumor cell invasion into collagen matrix induced by fibroblast-derived hepatocyte growth factor.
Q36650869	Insight On Colorectal Carcinoma Infiltration by Studying Perilesional Extracellular Matrix
Q28817630	Insights into Biochemical Alteration in Cancer-Associated Fibroblasts by using Novel Correlative Spectroscopy
Q38029555	Insights into cancer metastasis from a clinicopathologic perspective: Epithelial-Mesenchymal Transition is not a necessary step
Q39691733	Insulin promotes proliferative vitality and invasive capability of pancreatic cancer cells via hypoxia-inducible factor 1alpha pathway
Q36544603	Integrated gene and miRNA expression analysis of prostate cancer associated fibroblasts supports a prominent role for interleukin-6 in fibroblast activation
Q42593140	Integrated genome and transcriptome sequencing identifies a novel form of hybrid and aggressive prostate cancer
Q30356846	Integrated micro/nanoengineered functional biomaterials for cell mechanics and mechanobiology: a materials perspective.
Q91828460	Integrated tumor stromal features of hepatocellular carcinoma reveals two distinct subtypes with prognostic/predictive significance
Q34335849	Integrating macrophages into organotypic co-cultures: a 3D in vitro model to study tumor-associated macrophages
Q48053618	Integrating multiple microarray datasets on oral squamous cell carcinoma to reveal dysregulated networks
Q34762113	Integration of genotypic and phenotypic screening reveals molecular mediators of melanoma-stromal interaction.
Q49583565	Integrin Alpha V Beta 3 Targeted Dendrimer-Rapamycin Conjugate Reduces Fibroblast-Mediated Prostate Tumor Progression and Metastasis.
Q24677103	Integrin alpha 11 regulates IGF2 expression in fibroblasts to enhance tumorigenicity of human non-small-cell lung cancer cells
Q39325272	Integrin α11 is overexpressed by tumour stroma of head and neck squamous cell carcinoma and correlates positively with alpha smooth muscle actin expression.
Q38856297	Integrin α11β1 regulates cancer stromal stiffness and promotes tumorigenicity and metastasis in non-small cell lung cancer
Q57790100	Integrin αvβ6 Plays an Bi-directional Regulation Role Between Colon Cancer cells and Cancer-Associated Fibroblasts
Q34990234	Integrin-specific control of focal adhesion kinase and RhoA regulates membrane protrusion and invasion
Q37730158	Integrin-β4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells
Q92349966	Integrins, CAFs and Mechanical Forces in the Progression of Cancer
Q44086363	Intensity of stromal changes predicts biochemical recurrence-free survival in prostatic carcinoma
Q39205255	Interaction between lung cancer cell and myofibroblast influenced by cyclic tensile strain.
Q37781426	Interaction between the extracellular matrix and lymphatics: consequences for lymphangiogenesis and lymphatic function
Q52550597	Interaction of prostate carcinoma-associated fibroblasts with human epithelial cell lines in vivo.
Q38184985	Interaction of tumour cells with their microenvironment: ion channels and cell adhesion molecules. A focus on pancreatic cancer
Q39233221	Interaction with colon cancer cells hyperactivates TGF-β signaling in cancer-associated fibroblasts
Q36484558	Interactions between microenvironment and cancer cells in two animal models of bone metastasis
Q38184981	Interactions of ion transporters and channels with cancer cell metabolism and the tumour microenvironment.
Q34610562	Interactions with fibroblasts are distinct in Basal-like and luminal breast cancers.
Q34428998	Intercellular cooperation and competition in brain cancers: lessons from Drosophila and human studies.
Q49199768	Interferon-γ and Colorectal Cancer: an up-to date.
Q91981799	Interleukin-17F Has Anti-Tumor Effects in Oral Tongue Cancer
Q36730586	Interleukin-1β promotes ovarian tumorigenesis through a p53/NF-κB-mediated inflammatory response in stromal fibroblasts
Q28486177	Interleukin-6 mediates epithelial-stromal interactions and promotes gastric tumorigenesis
Q45162655	Interleukin-6 receptor in spindle-shaped stromal cells, a prognostic determinant of early breast cancer.
Q37507447	Interleukin-6 released by colon cancer-associated fibroblasts is critical for tumour angiogenesis: anti-interleukin-6 receptor antibody suppressed angiogenesis and inhibited tumour-stroma interaction
Q28082347	Interplay between ROS and autophagy in cancer cells, from tumor initiation to cancer therapy
Q92382382	Interplay of fibroblasts with anaplastic tumor cells promotes follicular thyroid cancer progression
Q37513831	Interplay of tumor microenvironment cell types with parenchymal cells in pancreatic cancer development and therapeutic implications
Q60958556	Interstitial Fluid in Gynecologic Tumors and Its Possible Application in the Clinical Practice
Q26822264	Interstitial fluid and lymph formation and transport: physiological regulation and roles in inflammation and cancer
Q34060641	Interstitial fluid: the overlooked component of the tumor microenvironment?
Q28082707	Intertwining of Activin A and TGFβ Signaling: Dual Roles in Cancer Progression and Cancer Cell Invasion
Q37337701	Intestinal GUCY2C prevents TGF-β secretion coordinating desmoplasia and hyperproliferation in colorectal cancer
Q34289166	Intestinal Mesenchymal Cells
Q92809240	Intracellular Notch1 Signaling in Cancer-Associated Fibroblasts Dictates the Plasticity and Stemness of Melanoma Stem/Initiating Cells
Q41298234	Intratumoral accumulation of podoplanin-expressing lymph node stromal cells promote tumor growth through elimination of CD4+ tumor-infiltrating lymphocytes
Q64088510	Intratumoral heterogeneity as measured using the tumor-stroma ratio and PET texture analyses in females with lung adenocarcinomas differs from that of males with lung adenocarcinomas or squamous cell carcinomas
Q38993432	Intratumoral phenotypic heterogeneity as an encourager of cancer invasion
Q33653155	Intravital imaging of stromal cell dynamics in tumors
Q35474544	Intravital imaging reveals how BRAF inhibition generates drug-tolerant microenvironments with high integrin β1/FAK signaling
Q61449497	Intriguing Relationships Between Cancer and Systemic Sclerosis: Role of the Immune System and Other Contributors
Q36458763	Intrinsic genetic characteristics determine tumor-modifying capacity of fibroblasts: matrix metalloproteinase-3 5A/5A genotype enhances breast cancer cell invasion.
Q37945305	Intrinsic modulation of lymphocyte function by stromal cell network: advance in therapeutic targeting of cancer
Q38352021	Introduction to the molecular basis of cancer metabolism and the Warburg effect
Q34359125	Involvement of host stroma cells and tissue fibrosis in pancreatic tumor development in transgenic mice
Q48183968	Involvement of local renin-angiotensin system in immunosuppression of tumor microenvironment.
Q33664889	Involvement of stromal p53 in tumor-stroma interactions.
Q53287029	Ion channels and transporters in cancer. 3. Ion channels in the tumor cell-microenvironment cross talk.
Q33600872	Ionizing radiation abrogates the pro-tumorigenic capacity of cancer-associated fibroblasts co-implanted in xenografts
Q37274962	Ionizing radiation-mediated premature senescence and paracrine interactions with cancer cells enhance the expression of syndecan 1 in human breast stromal fibroblasts: the role of TGF-β.
Q40075493	Is cholesterol a mediator of cold-induced cancer?
Q33570447	Isoform-specific upregulation of palladin in human and murine pancreas tumors
Q35130596	Isolation and characterization of mammalian cells expressing the Arf promoter during eye development
Q90657588	Isolation of cancer-associated fibroblasts and its promotion to the progression of intrahepatic cholangiocarcinoma
Q36639177	Isolation of normal and cancer-associated fibroblasts from fresh tissues by Fluorescence Activated Cell Sorting (FACS)
Q58738114	Jack of many trades: Multifaceted role of neuropilins in pancreatic cancer
Q37815128	Jekyll and Hyde: the role of the microenvironment on the progression of cancer
Q33858490	KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma.
Q47316195	Ketamine-induced bladder fibrosis involves epithelial-to-mesenchymal transition mediated by transforming growth factor-β1.
Q26766065	Key players in pancreatic cancer-stroma interaction: Cancer-associated fibroblasts, endothelial and inflammatory cells
Q34135320	Kinase domain activation of FGFR2 yields high-grade lung adenocarcinoma sensitive to a Pan-FGFR inhibitor in a mouse model of NSCLC
Q36413000	Knock out of the BASIGIN/CD147 chaperone of lactate/H+ symporters disproves its pro-tumour action via extracellular matrix metalloproteases (MMPs) induction
Q21144868	Knock-in reporter mice demonstrate that DNA repair by non-homologous end joining declines with age
Q91692530	Label-free molecular profiling for identification of biomarkers in carcinogenesis using multimodal multiphoton imaging
Q38394603	Laminin-5 gamma 2 chain expression is associated with intensity of tumor budding and density of stromal myofibroblasts in oral squamous cell carcinoma
Q35888797	Largescale Transcriptomics Analysis Suggests Over-Expression of BGH3, MMP9 and PDIA3 in Oral Squamous Cell Carcinoma
Q35938703	Laser Direct-Write Onto Live Tissues: A Novel Model for Studying Cancer Cell Migration
Q33314416	Laser-capture microdissection in prostate cancer research: establishment and validation of a powerful tool for the assessment of tumour-stroma interactions
Q80146610	Leading the charge
Q35971435	Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers
Q55031925	Let-7b inhibits cancer-promoting effects of breast cancer-associated fibroblasts through IL-8 repression.
Q50000643	Leukemia inhibitory factor produced by fibroblasts within tumor stroma participates in invasion of oral squamous cell carcinoma.
Q35779386	Leukocyte composition of human breast cancer
Q50231558	Licofelone abolishes survival of carcinogenic fibroblasts by inducing apoptosis.
Q35976594	Lipocalin produced by myelofibrosis cells affects the fate of both hematopoietic and marrow microenvironmental cells
Q41894153	Lipopolysaccharide induces a fibrotic-like phenotype in endothelial cells
Q37107139	Liquid-based three-dimensional tumor models for cancer research and drug discovery
Q36471637	Liver myofibroblasts regulate the phenotype and function of monocytes through soluble factors in cirrhosis
Q37052713	Liver regeneration and tumor stimulation--a review of cytokine and angiogenic factors.
Q41541435	Long Noncoding RNA JHDM1D-AS1 Promotes Tumor Growth by Regulating Angiogenesis in Response to Nutrient Starvation
Q41617899	Long-term changes in the properties of skin-derived fibroblasts following irradiation of the head and neck
Q30565493	Longitudinal confocal microscopy imaging of solid tumor destruction following adoptive T cell transfer.
Q34477782	Longitudinal study of mammary epithelial and fibroblast co-cultures using optical coherence tomography reveals morphological hallmarks of pre-malignancy.
Q37725460	Loss of MTSS1 results in increased metastatic potential in pancreatic cancer
Q37508329	Loss of TGF-β responsiveness in prostate stromal cells alters chemokine levels and facilitates the development of mixed osteoblastic/osteolytic bone lesions
Q37129107	Loss of adipocyte specification and necrosis augment tumor-associated inflammation
Q64946165	Loss of androgen receptor signaling in prostate cancer-associated fibroblasts (CAFs) promotes CCL2- and CXCL8-mediated cancer cell migration.
Q36276995	Loss of caveolin-1 alters extracellular matrix protein expression and ductal architecture in murine mammary glands
Q33874288	Loss of fibroblast HIF-1α accelerates tumorigenesis.
Q33882384	Loss of negative feedback control of nuclear factor-kappaB2 activity in lymphocytes leads to fatal lung inflammation.
Q36026081	Loss of one Tgfbr2 allele in fibroblasts promotes metastasis in MMTV: polyoma middle T transgenic and transplant mouse models of mammary tumor progression
Q53226402	Loss of p53 in stromal fibroblasts enhances tumor cell proliferation through nitric-oxide-mediated cyclooxygenase 2 activation.
Q38963422	Loss of the Timp gene family is sufficient for the acquisition of the CAF-like cell state
Q89551648	Low Dose Cyclophosphamide Modulates Tumor Microenvironment by TGF-β Signaling Pathway
Q58777726	Low-dose eribulin mesylate exerts antitumor effects in gastric cancer by inhibiting fibrosis via the suppression of epithelial-mesenchymal transition and acts synergistically with 5-fluorouracil
Q34806507	Lumican Accelerates Wound Healing by Enhancing α2β1 Integrin-Mediated Fibroblast Contractility
Q39237924	Lung carcinogenesis and fibrosis taken together: just coincidence?
Q50076951	Lung fibroblasts promote metastatic colonization through upregulation of stearoyl-CoA desaturase 1 in tumor cells.
Q36707881	Lymphangiogenesis in Breast Cancer Correlates with Matrix Stiffness on Shear-Wave Elastography.
Q37987842	Lymphatic and interstitial flow in the tumour microenvironment: linking mechanobiology with immunity
Q64114248	Lysyl Oxidase-Like Protein 2 Promotes Tumor Lymphangiogenesis and Lymph Node Metastasis in Breast Cancer
Q35183870	Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma
Q37437254	MARCKS contributes to stromal cancer-associated fibroblast activation and facilitates ovarian cancer metastasis.
Q39309649	MEMO1, a new IRS1-interacting protein, induces epithelial-mesenchymal transition in mammary epithelial cells
Q50317688	MMTV-NeuT/ATTAC mice: a new model for studying the stromal tumor microenvironment.
Q37875004	MRI & MRS assessment of the role of the tumour microenvironment in response to therapy.
Q80176069	MT1-MMP is required for efficient tumor dissemination in experimental metastatic disease
Q39517668	MT1-MMP protects breast carcinoma cells against type I collagen-induced apoptosis.
Q35753606	MYC is expressed in the stromal and epithelial cells of primary breast carcinoma and paired nodal metastases.
Q88377587	MYC sets a tumour-stroma metabolic loop
Q36198192	Macrophage-mediated lymphangiogenesis: the emerging role of macrophages as lymphatic endothelial progenitors
Q57816590	Macrophages and Fibroblasts, Key Players in Cancer Chemoresistance
Q37943796	Macrophages are important mediators of either tumor- or inflammation-induced lymphangiogenesis
Q34309316	Malignant stroma increases luminal breast cancer cell proliferation and angiogenesis through platelet-derived growth factor signaling
Q37003477	Mammary fibroblasts regulate morphogenesis of normal and tumorigenic breast epithelial cells by mechanical and paracrine signals
Q35536378	Mammary transplantation of stromal cells and carcinoma cells in C57BL/6J mice
Q36643000	Mammographic density. Potential mechanisms of breast cancer risk associated with mammographic density: hypotheses based on epidemiological evidence
Q28074177	Mammographic density: a potential monitoring biomarker for adjuvant and preventative breast cancer endocrine therapies
Q89482545	Manipulating the tumor microenvironment by adoptive cell transfer of CAR T-cells
Q61657666	Manufacturing Mesenchymal Stromal Cells for the Treatment of Graft-versus-Host Disease: A Survey among Centers Affiliated with the European Society for Blood and Marrow Transplantation
Q28678685	Mapping proteolytic processing in the secretome of gastric cancer-associated myofibroblasts reveals activation of MMP-1, MMP-2, and MMP-3
Q30542280	Mapping the extracellular and membrane proteome associated with the vasculature and the stroma in the embryo
Q34427796	Markers of epidermal stem cell subpopulations in adult mammalian skin
Q39356113	Matricellular proteins in cancer: a focus on secreted Frizzled-related proteins
Q43164806	Matricellular proteins produced by melanocytes and melanomas: in search for functions
Q36663581	Matricellular proteins: priming the tumour microenvironment for cancer development and metastasis
Q92423949	Matrix Metalloproteinase-sensitive Multistage Nanogels Promote Drug Transport in 3D Tumor Model
Q35107715	Matrix metalloproteinase (MMP)-9 in cancer-associated fibroblasts (CAFs) is suppressed by omega-3 polyunsaturated fatty acids in vitro and in vivo
Q35159014	Matrix remodeling stimulates stromal autophagy, "fueling" cancer cell mitochondrial metabolism and metastasis
Q37616743	Matrix-regulated integrin αvβ5 maintains α5β1-dependent desmoplastic traits prognostic of neoplastic recurrence.
Q39279824	Mechanical properties of the tumor stromal microenvironment probed in vitro and ex vivo by in situ-calibrated optical trap-based active microrheology
Q38651941	Mechanical response of collagen networks to nonuniform microscale loads
Q47141360	Mechanically tuned 3 dimensional hydrogels support human mammary fibroblast growth and viability.
Q91999628	Mechanism for oral tumor cell lysyl oxidase like-2 in cancer development: synergy with PDGF-AB
Q38872160	Mechanism of irradiation-induced mammary cancer metastasis: A role for SAP-dependent Mkl1 signaling
Q38819710	Mechanisms of Perineural Invasion
Q33755906	Mechanisms of disease: epithelial-mesenchymal transition--does cellular plasticity fuel neoplastic progression?
Q29620307	Mechanisms of fibrosis: therapeutic translation for fibrotic disease
Q34972161	Mechanisms of resistance to anti-angiogenic therapy and development of third-generation anti-angiogenic drug candidates
Q28070094	Mechanisms of the alternative activation of macrophages and non-coding RNAs in the development of radiation-induced lung fibrosis
Q50089395	Mechanisms regulating T-cell infiltration and activity in solid tumors.
Q88697944	Mechanisms that drive inflammatory tumor microenvironment, tumor heterogeneity, and metastatic progression
Q37766260	Mechanistic insights into acquired drug resistance in epidermal growth factor receptor mutation-targeted lung cancer therapy
Q35877893	Mechanobiology of tumor invasion: engineering meets oncology
Q37331580	Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts.
Q36918170	Melanoma Cells Block PEDF Production in Fibroblasts to Induce the Tumor-Promoting Phenotype of Cancer-Associated Fibroblasts
Q39459200	Melanoma cells control HA synthesis in peritumoral fibroblasts via PDGF-AA and PDGF-CC: impact on melanoma cell proliferation
Q39466119	Melanoma miRNA trafficking controls tumour primary niche formation
Q37469815	Melanoma-associated fibroblasts modulate NK cell phenotype and antitumor cytotoxicity
Q35067933	Melanoma-initiating cells exploit M2 macrophage TGFβ and arginase pathway for survival and proliferation.
Q33880433	Membrane type 1 matrix metalloproteinase-mediated stromal syndecan-1 shedding stimulates breast carcinoma cell proliferation
Q37702090	Membrane-bound ICAM-1 contributes to the onset of proinvasive tumor stroma by controlling acto-myosin contractility in carcinoma-associated fibroblasts
Q28084572	Membrane-to-Nucleus Signals and Epigenetic Mechanisms for Myofibroblastic Activation and Desmoplastic Stroma: Potential Therapeutic Targets for Liver Metastasis?
Q28383835	Meningeal norepinephrine produces headache behaviors in rats via actions both on dural afferents and fibroblasts
Q37156520	Mesenchymal CD44 expression contributes to the acquisition of an activated fibroblast phenotype via TWIST activation in the tumor microenvironment
Q37674735	Mesenchymal Stem Cell-Induced DDR2 Mediates Stromal-Breast Cancer Interactions and Metastasis Growth
Q27305351	Mesenchymal Stem Cells Induce Directional Migration of Invasive Breast Cancer Cells through TGF-β
Q51703464	Mesenchymal Stem Cells are Recruited and Activated into Carcinoma-Associated Fibroblasts by Prostate Cancer Microenvironment-Derived TGF-β1.
Q93047604	Mesenchymal Stem/Stromal Cell Engulfment Reveals Metastatic Advantage in Breast Cancer
Q55235695	Mesenchymal Stromal Cells: Emerging Roles in Bone Metastasis.
Q37125569	Mesenchymal cells of the intestinal lamina propria
Q33753147	Mesenchymal cells stimulate capillary morphogenesis via distinct proteolytic mechanisms.
Q37921954	Mesenchymal niches of bone marrow in cancer
Q33427809	Mesenchymal stem cell transition to tumor-associated fibroblasts contributes to fibrovascular network expansion and tumor progression
Q38736947	Mesenchymal stem cells as a double-edged sword in suppression or progression of solid tumor cells
Q26853374	Mesenchymal stem cells as a vector for the inflammatory prostate microenvironment
Q60203690	Mesenchymal stem cells from multiple myeloma patients display distinct genomic profile as compared with those from normal donors
Q49673155	Mesenchymal stem cells in breast cancer: response to chemical and mechanical stimuli.
Q39250469	Mesenchymal stem cells regulate epithelial-mesenchymal transition and tumor progression of pancreatic cancer cells
Q37358415	Mesenchymal stem cells: the fibroblasts' new clothes?
Q37395883	Mesenchymal stroma: primary determinant and therapeutic target for epithelial cancer
Q37645095	Mesenchymal stromal cells (MSCs) and colorectal cancer: a troublesome twosome for the anti-tumour immune response?
Q90683248	Mesenchymal stromal cells in cancer: a review of their immunomodulatory functions and dual effects on tumor progression
Q39265746	Metabolic Cooperation and Competition in the Tumor Microenvironment: Implications for Therapy.
Q26786595	Metabolic reprogramming: the emerging concept and associated therapeutic strategies
Q44123534	Metabolism targeting therapy of dichloroacetate-loaded electrospun mats on colorectal cancer
Q42315708	Metallic nanoparticles reduce the migration of human fibroblasts in vitro
Q51416828	Metastasis in context: modeling the tumor microenvironment with cancer-on-a-chip approaches.
Q38776120	Metastasized lung cancer suppression by Morinda citrifolia (Noni) leaf compared to Erlotinib via anti-inflammatory, endogenous antioxidant responses and apoptotic gene activation.
Q35580080	Metastatic breast cancer cells in lymph nodes increase nodal collagen density
Q41528278	Metastatic outgrowth encompasses COL-I, FN1, and POSTN up-regulation and assembly to fibrillar networks regulating cell adhesion, migration, and growth
Q35019643	Methylation determines fibroblast activation and fibrogenesis in the kidney
Q37500307	Metronomic chemotherapy prevents therapy-induced stromal activation and induction of tumor-initiating cells.
Q38721848	MiR-124 down-regulation is critical for cancer associated fibroblasts-enhanced tumor growth of oral carcinoma
Q47118717	MiR-205/YAP1 in Activated Fibroblasts of Breast Tumor Promotes VEGF-independent Angiogenesis through STAT3 Signaling
Q35155103	MiR-21 expression in the tumor stroma of oral squamous cell carcinoma: an independent biomarker of disease free survival
Q33907195	MiR-302c inhibits tumor growth of hepatocellular carcinoma by suppressing the endothelial-mesenchymal transition of endothelial cells
Q37745389	MiRNA199a-3p suppresses tumor growth, migration, invasion and angiogenesis in hepatocellular carcinoma by targeting VEGFA, VEGFR1, VEGFR2, HGF and MMP2.
Q27010255	MicroRNA regulation in cancer-associated fibroblasts
Q38240791	MicroRNA regulons in tumor microenvironment.
Q38993513	MicroRNA-106b in cancer-associated fibroblasts from gastric cancer promotes cell migration and invasion by targeting PTEN.
Q35051479	MicroRNA-143 regulates collagen type III expression in stromal fibroblasts of scirrhous type gastric cancer
Q93087093	MicroRNA-222 reprogrammed cancer-associated fibroblasts enhance growth and metastasis of breast cancer
Q90403264	MicroRNA-27a (miR-27a) in Solid Tumors: A Review Based on Mechanisms and Clinical Observations
Q38418114	MicroRNAs as mediators and communicators between cancer cells and the tumor microenvironment
Q39676479	MicroRNAs as molecular classifiers for cancer
Q36493077	MicroRNAs play a big role in regulating ovarian cancer-associated fibroblasts and the tumor microenvironment
Q54484920	Microarray analysis of Dupuytren's disease cells: the profibrogenic role of the TGF-β inducible p38 MAPK pathway.
Q35866337	Microencapsulation of Neuroblastoma Cells and Mesenchymal Stromal Cells in Collagen Microspheres: A 3D Model for Cancer Cell Niche Study
Q38810462	Microengineered cancer-on-a-chip platforms to study the metastatic microenvironment
Q37022156	Microengineered tumor models: insights & opportunities from a physical sciences-oncology perspective
Q30464008	Microengineering methods for cell-based microarrays and high-throughput drug-screening applications
Q38913083	Microenvironment drug resistance in multiple myeloma: emerging new players
Q39062505	Microenvironment in determining chemo-resistance in pancreatic cancer: Neighborhood matters.
Q38588066	Microenvironment in metastasis: roadblocks and supportive niches
Q36743563	Microenvironment of the involuting mammary gland mediates mammary cancer progression
Q33786788	Microenvironment, oncoantigens, and antitumor vaccination: lessons learned from BALB-neuT mice
Q37679978	Microenvironment-dependent cues trigger miRNA-regulated feedback loop to facilitate the EMT/MET switch.
Q52660791	Microenvironmental control of breast cancer subtype elicited through paracrine platelet-derived growth factor-CC signaling.
Q37439314	Microenvironmental independence associated with tumor progression
Q34444593	Microenvironmental influences that drive progression from benign breast disease to invasive breast cancer
Q29547660	Microenvironmental regulation of metastasis
Q43169264	Microenvironmental regulation of the progression of oral potentially malignant disorders towards malignancy
Q33654609	Microenvironmental regulation of therapeutic response in cancer
Q29615504	Microenvironmental regulation of tumor progression and metastasis
Q37100566	Migratory neighbors and distant invaders: tumor-associated niche cells
Q37091367	Mimicking Metastases Including Tumor Stroma: A New Technique to Generate a Three-Dimensional Colorectal Cancer Model Based on a Biological Decellularized Intestinal Scaffold
Q40512512	Mitochondrial Oxidative Stress due to Complex I Dysfunction Promotes Fibroblast Activation and Melanoma Cell Invasiveness.
Q46362794	Model of vascular desmoplastic multispecies tumor growth
Q53037013	Modeling Breast Tumor Development with a Humanized Mouse Model.
Q26800085	Modes of cancer cell invasion and the role of the microenvironment
Q37090422	Modulated expression of WFDC1 during carcinogenesis and cellular senescence
Q47315881	Modulating secreted components of tumor microenvironment: A masterstroke in tumor therapeutics.
Q34053962	Modulation of TNF-induced macrophage polarization by synovial fibroblasts.
Q39391322	Modulation of tumor microenvironment by chemopreventive natural products
Q57802920	Molecular Mechanisms of Long Noncoding RNAs-medicated Cancer Metastasis
Q38869424	Molecular Targeting of Integrins and Integrin-Associated Signaling Networks in Radiation Oncology.
Q38077373	Molecular communication between tumor-associated fibroblasts and head and neck squamous cell carcinoma
Q96952383	Molecular dissection of CRC primary tumors and their matched liver metastases reveals critical role of immune microenvironment, EMT and angiogenesis in cancer metastasis
Q38354860	Molecular mechanism underlying the tumor-promoting functions of carcinoma-associated fibroblasts.
Q37918848	Molecular mechanisms of liver metastasis
Q34065560	Molecular pathogenesis of cholangiocarcinoma
Q34775377	Molecular profiling of stroma identifies osteopontin as an independent predictor of poor prognosis in intrahepatic cholangiocarcinoma
Q34770823	Molecular profiling predicts the existence of two functionally distinct classes of ovarian cancer stroma
Q26751709	Molecular therapeutics in pancreas cancer
Q34190300	Morphometric characteristics of basal cell carcinoma peritumoral stroma varies among basal cell carcinoma subtypes
Q36602578	Mouse models of BRCA1 and BRCA2 deficiency: past lessons, current understanding and future prospects
Q41664785	Mouse models of metastasis: progress and prospects.
Q79988524	Mucinous cystadenocarcinoma of the pancreas developing during hormone replacement therapy
Q38688450	Mueller polarimetric imaging for surgical and diagnostic applications: a review
Q33737136	Multi-cancer computational analysis reveals invasion-associated variant of desmoplastic reaction involving INHBA, THBS2 and COL11A1.
Q26741948	Multidimensional Complexity of Cancer. Simple Solutions Are Needed
Q38045226	Multifaceted roles of PGE2 in inflammation and cancer
Q36284975	Multifaceted tumor stromal fibroblasts
Q27005678	Multifocal epithelial tumors and field cancerization: stroma as a primary determinant
Q36374096	Multigenerational epigenetic adaptation of the hepatic wound-healing response
Q33360100	Multiple actions of lysophosphatidic acid on fibroblasts revealed by transcriptional profiling
Q36307634	Multistage vector (MSV) therapeutics
Q64067726	Muscle functions as a connective tissue and source of extracellular matrix in planarians
Q41818426	Myeloid-derived suppressor cells and associated events in urethane-induced lung cancer
Q39450591	Myofibroblast-derived PDGF-BB promotes Hedgehog survival signaling in cholangiocarcinoma cells
Q54195617	Myofibroblasts from salivary gland adenoid cystic carcinomas promote cancer invasion by expressing MMP2 and CXCL12.
Q36840263	Myofibroblasts in pulmonary and brain metastases of alveolar soft-part sarcoma: a novel target for treatment?
Q27692541	Myofibroblasts: trust your heart and let fate decide.
Q98943964	Myxoid stroma is associated with postoperative relapse in patients with stage II colon cancer
Q37395723	NLRC4 suppresses melanoma tumor progression independently of inflammasome activation
Q36001853	NOTCH3 Is Induced in Cancer-Associated Fibroblasts and Promotes Angiogenesis in Oral Squamous Cell Carcinoma
Q36771836	NOVA1 inhibition by miR-146b-5p in the remnant tissue microenvironment defines occult residual disease after gastric cancer removal.
Q64098474	Nano-Strategies to Target Breast Cancer-Associated Fibroblasts: Rearranging the Tumor Microenvironment to Achieve Antitumor Efficacy
Q92832813	Nano-mechanical mapping of interdependent cell and ECM mechanics by AFM force spectroscopy
Q39380111	Nanoformulations for combination or cascade anticancer therapy.
Q48646732	Nanomaterials for cancer immunotherapy.
Q37693046	Nanoparticles containing insoluble drug for cancer therapy
Q33804264	Nanotechniques Inactivate Cancer Stem Cells
Q59807976	Natural Products to Fight Cancer: A Focus on Juglans regia
Q64081261	Neddylation: a novel modulator of the tumor microenvironment
Q37118737	Negative control of CSL gene transcription by stress/DNA damage response and p53.
Q41129667	Nemosis of fibroblasts is inhibited by benign HaCaT keratinocytes but promoted by malignant HaCaT cells
Q37418297	Nemosis, a novel way of fibroblast activation, in inflammation and cancer
Q35969445	Neoangiogenesis. Assessment in Esophageal Adenocarcinomas
Q43627381	Neonatal human dermal fibroblasts immobilized in RGD-alginate induce angiogenesis.
Q36618752	Neoplastic and stromal cells contribute to an extracellular matrix gene expression profile defining a breast cancer subtype likely to progress
Q64891197	Neuropilin-1 aggravates liver cirrhosis by promoting angiogenesis via VEGFR2-dependent PI3K/Akt pathway in hepatic sinusoidal endothelial cells.
Q30495328	Neuropilin-1 promotes cirrhosis of the rodent and human liver by enhancing PDGF/TGF-beta signaling in hepatic stellate cells
Q50042197	New Insights into the Tumor Microenvironment Utilizing Protein Array Technology.
Q34382914	New advances on critical implications of tumor- and metastasis-initiating cells in cancer progression, treatment resistance and disease recurrence
Q42239363	New and paradoxical roles of matrix metalloproteinases in the tumor microenvironment.
Q37860751	Niche contributions to oncogenesis: emerging concepts and implications for the hematopoietic system
Q35073159	Niche-dependent gene expression profile of intratumoral heterogeneous ovarian cancer stem cell populations
Q37099675	Niemann-pick type C2 deficiency in human fibroblasts confers robust and selective activation of prostaglandin E2 biosynthesis.
Q89519070	Nintedanib inhibits intrahepatic cholangiocarcinoma aggressiveness via suppression of cytokines extracted from activated cancer-associated fibroblasts
Q43158982	Nintedanib selectively inhibits the activation and tumour-promoting effects of fibroblasts from lung adenocarcinoma patients.
Q35670576	Nintedanib, a triple angiokinase inhibitor, enhances cytotoxic therapy response in pancreatic cancer.
Q36891506	Nitric oxide regulates tumor cell cross-talk with stromal cells in the tumor microenvironment of the liver
Q28581539	Nkx2.5/Csx represses myofibroblast differentiation
Q33507097	Non-Linear Optical Imaging of Obesity-Related Health Risks: Review
Q33761396	Non-glycanated Decorin Is a Drug Target on Human Adipose Stromal Cells
Q59327125	Non-hematopoietic Control of Peripheral Tissue T Cell Responses: Implications for Solid Tumors
Q51021428	Non-small-cell lung cancer.
Q27304413	Noninvasive In-Vivo Quantification of Mechanical Heterogeneity of Invasive Breast Carcinomas
Q42434242	Norepinephrine promotes tumor microenvironment reactivity through β3-adrenoreceptors during melanoma progression
Q37157064	Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription
Q30542073	Normalizing tumor microenvironment to treat cancer: bench to bedside to biomarkers
Q90668015	Not gene therapy, but genetic surgery-the right strategy to attack cancer
Q41848834	Notch1-WISP-1 axis determines the regulatory role of mesenchymal stem cell-derived stromal fibroblasts in melanoma metastasis
Q26824909	Novel hepatocellular carcinoma molecules with prognostic and therapeutic potentials
Q42144287	Novel mechanism of cardiac protection by valsartan: synergetic roles of TGF-β1 and HIF-1α in Ang II-mediated fibrosis after myocardial infarction
Q30360377	Novel regulatory role of neuropilin-1 in endothelial-to-mesenchymal transition and fibrosis in pancreatic ductal adenocarcinoma
Q39456875	Nutrient Exploitation within the Tumor-Stroma Metabolic Crosstalk
Q28067777	Ockham's razor for the MET-driven invasive growth linking idiopathic pulmonary fibrosis and cancer
Q39642324	Old proteins - new locations: myoglobin, haemoglobin, neuroglobin and cytoglobin in solid tumours and cancer cells.
Q47571257	On the mechanism of long-range orientational order of fibroblasts
Q39016730	Optimization of liquid overlay technique to formulate heterogenic 3D co-cultures models
Q35210099	Optimizing a 3D Culture System to Study the Interaction between Epithelial Breast Cancer and Its Surrounding Fibroblasts
Q38905001	Organ-on-a-Chip Systems: Microengineering to Biomimic Living Systems
Q36837236	Organotypic models of metastasis: A three-dimensional culture mimicking the human peritoneum and omentum for the study of the early steps of ovarian cancer metastasis
Q52429973	Organotypic three-dimensional assays based on human leiomyoma-derived matrices.
Q37628341	Origin of cardiac fibroblasts and the role of periostin
Q37716879	Origin, development, and differentiation of cardiac fibroblasts
Q34994026	Origins of cardiac fibroblasts
Q26749570	Osteopontin-A Master Regulator of Epithelial-Mesenchymal Transition
Q49631372	Osteopontin-integrin engagement induces HIF-1α-TCF12-mediated endothelial-mesenchymal transition to exacerbate colorectal cancer.
Q36311002	Osteopontin-integrin interaction as a novel molecular target for antibody-mediated immunotherapy in adult T-cell leukemia
Q98208978	Osterix-Cre marks distinct subsets of CD45- and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics
Q95840383	Ovarian Cancer Exosomes Trigger Differential Biophysical Response in Tumor-Derived Fibroblasts
Q37033701	Ovarian normal and tumor-associated fibroblasts retain in vivo stromal characteristics in a 3-D matrix-dependent manner
Q53739678	Overcoming the tumor microenvironment: the role of nanohyperthermia.
Q35032539	Overexpression of COL11A1 by cancer-associated fibroblasts: clinical relevance of a stromal marker in pancreatic cancer
Q37677701	Overexpression of caveolin-1 in cancer-associated fibroblasts predicts good outcome in breast cancer
Q36780735	Overexpression of monocarboxylate anion transporter 1 and 4 in T24-induced cancer-associated fibroblasts regulates the progression of bladder cancer cells in a 3D microfluidic device
Q80569126	Overexpression of myocyte enhancer factor 2 and histone hyperacetylation in hepatocellular carcinoma
Q36516942	Overview of human primary tumorgraft models: comparisons with traditional oncology preclinical models and the clinical relevance and utility of primary tumorgrafts in basic and translational oncology research
Q24619475	Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells
Q36039273	Oxidative stress promotes myofibroblast differentiation and tumour spreading
Q42178112	Oxidative stress, tumor microenvironment, and metabolic reprogramming: a diabolic liaison
Q52664220	P-Selectin Sustains Extramedullary Hematopoiesis in the Gata1 low Model of Myelofibrosis.
Q34746645	P190B RhoGAP overexpression in the developing mammary epithelium induces TGFβ-dependent fibroblast activation
Q89907649	P53 Mutant p53N236S Regulates Cancer-Associated Fibroblasts Properties Through Stat3 Pathway
Q52723837	PAI1 mediates fibroblast-mast cell interactions in skin fibrosis.
Q34778528	PARP-1 regulates metastatic melanoma through modulation of vimentin-induced malignant transformation.
Q35147563	PARVA promotes metastasis by modulating ILK signalling pathway in lung adenocarcinoma
Q92960661	PD-L1 Induction by Cancer-Associated Fibroblast-Derived Factors in Lung Adenocarcinoma Cells
Q39433494	PDGF-BB modulates hematopoiesis and tumor angiogenesis by inducing erythropoietin production in stromal cells
Q58803894	PDGF/PDGFR effects in osteosarcoma and the "add-on" strategy
Q36003190	PDGFRβ Is a Novel Marker of Stromal Activation in Oral Squamous Cell Carcinomas
Q83610980	PDGFRβ expression in tumor stroma of pancreatic adenocarcinoma as a reliable prognostic marker
Q53263829	PGRN promotes migration and invasion of epithelial ovarian cancer cells through an epithelial mesenchymal transition program and the activation of cancer associated fibroblasts.
Q89991493	PIK3Cδ expression by fibroblasts promotes triple-negative breast cancer progression
Q39924024	PLP2, a potent deubiquitinase from murine hepatitis virus, strongly inhibits cellular type I interferon production
Q33418311	PTCH1 +/- dermal fibroblasts isolated from healthy skin of Gorlin syndrome patients exhibit features of carcinoma associated fibroblasts
Q38629644	PTEN and PI3K/AKT in non-small-cell lung cancer.
Q38447860	PTRF/cavin-1 neutralizes non-caveolar caveolin-1 microdomains in prostate cancer
Q91284099	PU.1 controls fibroblast polarization and tissue fibrosis
Q38850479	Palladin mediates stiffness-induced fibroblast activation in the tumor microenvironment
Q40001815	Pancreatic cancer associated fibroblasts display normal allelotypes.
Q39781987	Pancreatic cancer cells activate CCL5 expression in mesenchymal stromal cells through the insulin-like growth factor-I pathway
Q64462058	Partial reprogramming induces a steady decline in epigenetic age before loss of somatic identity
Q34656747	Pathogenesis, diagnosis, and management of cholangiocarcinoma
Q36888327	Pazopanib inhibits the activation of PDGFRβ-expressing astrocytes in the brain metastatic microenvironment of breast cancer cells
Q38912989	Peptide assembly integration of fibroblast-targeting and cell-penetration features for enhanced antitumor drug delivery
Q64058113	Peri-tumor fibroblasts promote tumorigenesis and metastasis of hepatocellular carcinoma via Interleukin6/STAT3 signaling pathway
Q37281490	Pericyte-fibroblast transition promotes tumor growth and metastasis.
Q92421258	Pericytes in Metastasis
Q57801748	Periostin secreted by cancer-associated fibroblasts promotes cancer stemness in head and neck cancer by activating protein tyrosine kinase 7
Q34519639	Periostin suppression induces decorin secretion leading to reduced breast cancer cell motility and invasion
Q35915338	Peritumoral SPARC expression and patient outcome with resectable intrahepatic cholangiocarcinoma
Q37128159	Perivascular fibroblasts form the fibrotic scar after contusive spinal cord injury
Q55078362	Persistent DNA strand breaks induce a CAF-like phenotype in normal fibroblasts.
Q27012236	Persistent activation of pancreatic stellate cells creates a microenvironment favorable for the malignant behavior of pancreatic ductal adenocarcinoma
Q37604680	Persistent stromal fibroblast activation is present in chronic tendinopathy.
Q38549236	Perspective of Targeting Cancer-Associated Fibroblasts in Melanoma
Q30443756	Perspective: Flicking with flow: Can microfluidics revolutionize the cancer research?
Q90432246	Perspective: bidirectional exosomal transport between cancer stem cells and their fibroblast-rich microenvironment during metastasis formation
Q60951233	Phage Ligands for Identification of Mesenchymal-Like Breast Cancer Cells and Cancer-Associated Fibroblasts
Q92364940	Phage display screening of therapeutic peptide for cancer targeting and therapy
Q54346614	Phosphatidylinositol 5-phosphate regulates invasion through binding and activation of Tiam1.
Q37411837	Photodynamic molecular beacon triggered by fibroblast activation protein on cancer-associated fibroblasts for diagnosis and treatment of epithelial cancers
Q89389704	Photosensitizer-Encapsulated Ferritins Mediate Photodynamic Therapy against Cancer-Associated Fibroblasts and Improve Tumor Accumulation of Nanoparticles
Q37746085	Physico-mechanical aspects of extracellular matrix influences on tumorigenic behaviors
Q38582873	Physiological, Tumor, and Metastatic Niches: Opportunities and Challenges for Targeting the Tumor Microenvironment
Q37711835	Physiologically activated mammary fibroblasts promote postpartum mammary cancer
Q36123584	Physiology of the Renal Interstitium
Q35384921	Pituitary tumor transforming gene induces epithelial to mesenchymal transition by regulation of Twist, Snail, Slug, and E-cadherin
Q40884698	Plasticity of fibroblasts demonstrated by tissue-specific and function-related proteome profiling
Q38963431	Plasticity of tumor cell invasion: governance by growth factors and cytokines.
Q34044638	Platelet-derived growth factor primes cancer-associated fibroblasts for apoptosis.
Q39179249	Platelet-derived growth factor-D and Rho GTPases regulate recruitment of cancer-associated fibroblasts in cholangiocarcinoma
Q39410987	Pleiotropic Roles of Non-Coding RNAs in TGF-β-Mediated Epithelial-Mesenchymal Transition and Their Functions in Tumor Progression
Q26749146	Podoplanin - a small glycoprotein with many faces
Q85475870	Podoplanin expressing cancer associated fibroblasts are associated with unfavourable prognosis in adenocarcinoma of the esophagus
Q53027845	Podoplanin expressing cancer-associated fibroblasts in oral cancer.
Q37562162	Podoplanin expression in cancer-associated fibroblasts enhances tumor progression of invasive ductal carcinoma of the pancreas.
Q88207901	Podoplanin expression in the cyst wall correlates with the progression of intraductal papillary mucinous neoplasm
Q64273058	Podoplanin in Inflammation and Cancer
Q42362588	Podoplanin increases the migration of human fibroblasts and affects the endothelial cell network formation: A possible role for cancer-associated fibroblasts in breast cancer progression.
Q52670614	Podoplanin-positive cancer-associated fibroblast recruitment within cancer stroma is associated with a higher number of single nucleotide variants in cancer cells in lung adenocarcinoma.
Q28275310	Podoplanin: emerging functions in development, the immune system, and cancer
Q38893743	Polo-like kinase 3 is associated with improved overall survival in cholangiocarcinoma.
Q64930888	Poorly Differentiated Clusters Predict Colon Cancer Recurrence: An In-Depth Comparative Analysis of Invasive-Front Prognostic Markers.
Q37866794	Potential of CXCR4 antagonists for the treatment of metastatic lung cancer
Q34786543	Potential therapeutic effect of the secretome from human uterine cervical stem cells against both cancer and stromal cells compared with adipose tissue stem cells
Q49196561	Preclinical rationale for TGF-β inhibition as a therapeutic target for the treatment of myelofibrosis.
Q52553452	Preparation-related structural diversity and medical potential in the treatment of diabetes mellitus with ginseng pectins.
Q35945448	Presence of cancer-associated fibroblasts inversely correlates with Schwannian stroma in neuroblastoma tumors
Q57144510	Present and future of cancer immunotherapy: A tumor microenvironmental perspective
Q42454757	Primary breast tumor-derived cellular models: characterization of tumorigenic, metastatic, and cancer-associated fibroblasts in dissociated tumor (DT) cultures
Q34141711	Primary cilia are decreased in breast cancer: analysis of a collection of human breast cancer cell lines and tissues
Q49646730	Primed atypical ductal hyperplasia-associated fibroblasts promote cell growth and polarity changes of transformed epithelium-like breast cancer MCF-7 cells via miR-200b/c-IKKβ signaling.
Q38232067	Priming cancer cells for drug resistance: role of the fibroblast niche
Q48095809	Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding.
Q38059502	Pro-metastatic tumor-stroma interactions in breast cancer.
Q34384216	Probing biological nanotopology via diffusion of weakly constrained plasmonic nanorods with optical coherence tomography
Q39365067	Probing the role of mesenchymal stem cells in salivary gland cancer on biomimetic microdevices
Q38785389	Profiling lung adenocarcinoma by liquid biopsy: can one size fit all?
Q41503155	Prognostic Impact of Extracapsular Lymph Node Invasion and Myofibroblastic Activity in Extrahepatic Bile Duct Cancer
Q41371061	Prognostic Value of Metastatic Tumoral Caveolin-1 Expression in Patients with Resected Gastric Cancer
Q41880628	Prognostic and functional role of subtype-specific tumor-stroma interaction in breast cancer
Q92037295	Prognostic biomarkers for immunotherapy with ipilimumab in metastatic melanoma
Q30499935	Prognostic gene-expression signature of carcinoma-associated fibroblasts in non-small cell lung cancer
Q34658302	Prognostic impact of histological categorisation of epithelial-mesenchymal transition in colorectal cancer
Q43646189	Prognostic impact of tumoral and/or peri-tumoral stromal SPARC expressions after surgery in patients with biliary tract cancer
Q49178361	Prognostic significance of E-cadherin and ZEB1 expression in intraductal papillary mucinous neoplasm.
Q48010220	Prognostic significance of carbonic anhydrase IX expression by cancer-associated fibroblasts in lung adenocarcinoma
Q37257191	Prognostic significance of stromal platelet-derived growth factor beta-receptor expression in human breast cancer
Q104795283	Prognostic value of desmoplastic reaction characterisation in stage II colon cancer: prospective validation in a Phase 3 study (SACURA Trial)
Q50352443	Prognostic value of fibrosis ratio in metastatic lymph nodes of node-positive advanced gastric cancer.
Q99551776	Prognostic values of EDNRB in triple-negative breast cancer
Q98771735	Progress in Neoantigen Targeted Cancer Immunotherapies
Q39202934	Progression of genotype-specific oral cancer leads to senescence of cancer-associated fibroblasts and is mediated by oxidative stress and TGF-β.
Q36257609	Progressive Enrichment of Stemness Features and Tumor Stromal Alterations in Multistep Hepatocarcinogenesis
Q36413420	Prokineticin 2 (PROK2) is an important factor for angiogenesis in colorectal cancer
Q84094346	Proliferation of myofibroblasts in the stroma of renal oncocytoma
Q34929340	Pronounced cancer resistance in a subterranean rodent, the blind mole-rat, Spalax: in vivo and in vitro evidence.
Q60960769	Prospective Evaluation of Unprocessed Core Needle Biopsy DNA and RNA Yield from Lung, Liver, and Kidney Tumors: Implications for Cancer Genomics
Q49401353	Prospects for chimeric antigen receptor-modified T cell therapy for solid tumors.
Q50035774	Prospects to improve chimeric antigen receptor T-cell therapy for solid tumors.
Q38951674	Prostanoid induces premetastatic niche in regional lymph nodes
Q38668605	Prostate cancer stem cells: from theory to practice.
Q41535142	Prostate stromal cell proteomics analysis discriminates normal from tumour reactive stromal phenotypes.
Q37286948	Protease-activated receptor-1 is upregulated in reactive stroma of primary prostate cancer and bone metastasis
Q42746302	Protein kinase c-β-dependent activation of NF-κB in stromal cells is indispensable for the survival of chronic lymphocytic leukemia B cells in vivo.
Q54689509	Protein pathway biomarker analysis of human cancer reveals requirement for upfront cellular-enrichment processing.
Q37636855	Proteoglycans: master modulators of paracrine fibroblast-carcinoma cell interactions
Q35987073	Proteomic signatures of the desmoplastic invasion front reveal collagen type XII as a marker of myofibroblastic differentiation during colorectal cancer metastasis
Q52936872	Proteomics analysis of malignant and benign prostate tissue by 2D DIGE/MS reveals new insights into proteins involved in prostate cancer.
Q37399478	Pten in stromal fibroblasts suppresses mammary epithelial tumours
Q34786718	Pten in the breast tumor microenvironment: modeling tumor-stroma coevolution.
Q34626008	Pulse-chase analysis of procollagen biosynthesis by azidohomoalanine labeling.
Q34124481	Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growth
Q42277124	Quantification of Mesenchymal Stem Cells (MSCs) at sites of human prostate cancer
Q48206682	Quantification of altered tissue turnover in a liquid biopsy: a proposed precision medicine tool to assess chronic inflammation and desmoplasia associated with a pro-cancerous niche and response to immuno-therapeutic anti-tumor modalities.
Q30275479	Quantitative Analysis of the Cellular Microenvironment of Glioblastoma to Develop Predictive Statistical Models of Overall Survival
Q34145178	Quantitative analysis of the secretome of TGF-beta signaling-deficient mammary fibroblasts
Q44071623	Quantitative image analysis of cellular heterogeneity in breast tumors complements genomic profiling
Q61445563	Quantitative phase imaging reveals matrix stiffness-dependent growth and migration of cancer cells
Q55317564	Quantitative phosphoproteomic analysis reveals reciprocal activation of receptor tyrosine kinases between cancer epithelial cells and stromal fibroblasts.
Q59912703	Quantitative proteomic profiling of primary cancer-associated fibroblasts in oesophageal adenocarcinoma
Q37021841	Quantitative spectroscopic imaging for non-invasive early cancer detection
Q94586098	Quantitative stain-free imaging and digital profiling of collagen structure reveal diverse survival of triple negative breast cancer patients
Q38601575	RETRACTED ARTICLE: Sorcin Predicts Poor Prognosis and Promotes Metastasis by Facilitating Epithelial-mesenchymal Transition in Hepatocellular Carcinoma
Q21245504	Rac and Rho GTPases in cancer cell motility control
Q37382515	Radiation promotes epithelial-to-mesenchymal transition and invasion of pancreatic cancer cell by activating carcinoma-associated fibroblasts
Q27022685	Radiotherapy and the tumor stroma: the importance of dose and fractionation
Q96639861	Radiotherapy targeting cancer stem cells "awakens" them to induce tumour relapse and metastasis in oral cancer
Q28077930	Reactive oxygen species and fibrosis: further evidence of a significant liaison
Q53421985	Reactive stroma in the prostate during late life: The role of microvasculature and antiangiogenic therapy influences.
Q26797285	Recapitulating the Tumor Ecosystem Along the Metastatic Cascade Using 3D Culture Models
Q37620476	Recent Advances in Understanding, Diagnosing, and Treating Ovarian Cancer.
Q38111793	Recent advances in understanding inflammation and remodeling in the airways in chronic obstructive pulmonary disease
Q64100317	Recent advances in understanding tumor stroma-mediated chemoresistance in breast cancer
Q33730375	Recent advances on the molecular mechanisms involved in the drug resistance of cancer cells and novel targeting therapies
Q37089825	Recent progress on tissue-resident adult stem cell biology and their therapeutic implications
Q30300159	Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity.
Q34558918	Reciprocal interaction between carcinoma-associated fibroblasts and squamous carcinoma cells through interleukin-1α induces cancer progression
Q58092065	Reciprocal reprogramming of cancer cells and associated Mesenchymal Stem Cells in gastric cancer
Q35662257	Recruitment of Matrix Metalloproteinase-9 (MMP-9) to the Fibroblast Cell Surface by Lysyl Hydroxylase 3 (LH3) Triggers Transforming Growth Factor-β (TGF-β) Activation and Fibroblast Differentiation
Q53164626	Recruitment of podoplanin positive cancer-associated fibroblasts in metastatic lymph nodes predicts poor prognosis in pathological N2 stage III lung adenocarcinoma.
Q26786129	Redox-fibrosis: Impact of TGFβ1 on ROS generators, mediators and functional consequences
Q38383375	Redox-sensitive mechanisms underlying vascular dysfunction in heart failure
Q37408293	Reduced CX3CL1 Secretion Contributes to the Susceptibility of Oral Leukoplakia-Associated Fibroblasts to Candida albicans
Q37293806	Reduced Contractility and Motility of Prostatic Cancer-Associated Fibroblasts after Inhibition of Heat Shock Protein 90
Q28647000	Registered report: Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis
Q34268182	Regulation of ROCK1 via Notch1 during breast cancer cell migration into dense matrices.
Q37590325	Regulation of angiogenesis in malignancies associated with Epstein-Barr virus and Kaposi's sarcoma-associated herpes virus
Q26862059	Regulation of endothelial cell plasticity by TGF-β
Q35748219	Regulation of the inflammatory profile of stromal cells in human breast cancer: prominent roles for TNF-α and the NF-κB pathway
Q33734780	Regulation of tumor growth and metastasis: the role of tumor microenvironment
Q38948512	Regulatory T Cells and Cancer: A Two-Sided Story
Q38928127	Regulatory circuits of T cell function in cancer
Q33609069	Relationships of alpha-SMA-positive fibroblasts and SDF-1-positive tumor cells with neoangiogenesis in nasopharyngeal carcinoma
Q36402018	Release of TGFβig-h3 by gastric myofibroblasts slows tumor growth and is decreased with cancer progression.
Q37016995	Remodeling of tumor stroma and response to therapy
Q38979314	Reprogramming adult dermis to a neonatal state through epidermal activation of β-catenin
Q36107831	Reprogramming of Normal Fibroblasts into Cancer-Associated Fibroblasts by miRNAs-Mediated CCL2/VEGFA Signaling
Q35729814	Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320
Q28821190	Repurposed drug screen identifies cardiac glycosides as inhibitors of TGF-β-induced cancer-associated fibroblast differentiation
Q38633691	Repurposing itraconazole as an anticancer agent
Q44181118	Resveratrol Regulates Colorectal Cancer Cell Invasion by Modulation of Focal Adhesion Molecules.
Q99605264	Resveratrol and Tumor Microenvironment: Mechanistic Basis and Therapeutic Targets
Q84514067	Retinoic acid enhances skeletal myogenesis in human embryonic stem cells by expanding the premyogenic progenitor population
Q26771696	Reversible Human TGF-β Signal Shifting between Tumor Suppression and Fibro-Carcinogenesis: Implications of Smad Phospho-Isoforms for Hepatic Epithelial-Mesenchymal Transitions
Q38247899	Review: Cell Dynamics in Malignant Pleural Effusions
Q37189305	Revisiting the biological roles of PAI2 (SERPINB2) in cancer
Q37463413	Revisiting the seed and soil in cancer metastasis
Q34249114	Rho GTPases RhoA and Rac1 mediate effects of dietary folate on metastatic potential of A549 cancer cells through the control of cofilin phosphorylation
Q89587304	Rho-ROCK Signaling in Normal Physiology and as a Key Player in Shaping the Tumor Microenvironment
Q24631326	Rho-associated kinases in tumorigenesis: re-considering ROCK inhibition for cancer therapy
Q37682275	RhoA knockout fibroblasts lose tumor-inhibitory capacity in vitro and promote tumor growth in vivo
Q35970782	Robotic production of cancer cell spheroids with an aqueous two-phase system for drug testing
Q38970580	Role of Endothelial Cells and Fibroblasts in Multiple Myeloma Angiogenic Switch
Q64068152	Role of Exosomes in Crosstalk Between Cancer-Associated Fibroblasts and Cancer Cells
Q91674537	Role of Helicobacter pylori infection in cancer-associated fibroblast-induced epithelial-mesenchymal transition in vitro
Q52721968	Role of Stromal Paracrine Signals in Proliferative Diseases of the Aging Human Prostate.
Q40050341	Role of a Preorganized Scaffold Presenting Four Residues of a GM-3 Lactone Mimetic on Melanoma Progression.
Q36284948	Role of bone marrow-derived cells in angiogenesis: focus on macrophages and pericytes
Q28239062	Role of cancer microenvironment in metastasis: focus on colon cancer
Q92889830	Role of cancer-associated fibroblasts in tumor structure, composition and the microenvironment in ovarian cancer
Q36120825	Role of chemokines in tumor growth
Q34027977	Role of constitutive behavior and tumor-host mechanical interactions in the state of stress and growth of solid tumors
Q42917103	Role of epithelial mesenchymal transition (EMT) in chronic obstructive pulmonary disease (COPD).
Q29417845	Role of epithelial-mesenchymal transition (EMT) and fibroblast function in cerium oxide nanoparticles-induced lung fibrosis
Q35684545	Role of estrogen receptor signaling in breast cancer metastasis
Q47153204	Role of metastasis-induced protein S100A4 in human non-tumor pathophysiologies.
Q92366817	Role of microRNAs in remodeling the tumor microenvironment (Review)
Q33948361	Role of non-coding RNAs in pancreatic cancer: the bane of the microworld
Q26750359	Role of nuclear receptors in breast cancer stem cells
Q27003859	Role of oxidative stress and the microenvironment in breast cancer development and progression
Q33727318	Role of soluble guanylyl cyclase-cyclic GMP signaling in tumor cell proliferation
Q64974995	Role of the Hippo Pathway in Fibrosis and Cancer.
Q38083596	Role of the endothelial-to-mesenchymal transition in renal fibrosis of chronic kidney disease
Q37769582	Role of the metastasis-promoting protein osteopontin in the tumour microenvironment
Q36625697	Role of the microenvironment in the pathogenesis and treatment of hepatocellular carcinoma
Q38207013	Role of the tissue microenvironment as a therapeutic target in hepatocellular carcinoma
Q37596178	Role of the tumor microenvironment in the pathogenesis of gastric carcinoma
Q39726007	Role of tumor associated fibroblasts in human liver regeneration, cirrhosis, and cancer
Q55078149	Role of tumor microenvironment in ovarian cancer pathobiology.
Q58724750	Role of tumor microenvironment in the pathobiology of ovarian cancer: Insights and therapeutic opportunities
Q39449113	Role of tumor microenvironment in triple-negative breast cancer and its prognostic significance
Q37738074	Role of tumor microenvironment in tumorigenesis
Q42828684	Role of vasostatin-1 C-terminal region in fibroblast cell adhesion.
Q37339711	Roles of TGFbeta in metastasis
Q34413441	Roles of tumor suppressors in regulating tumor-associated inflammation
Q34839397	S100A4 expression in xenograft tumors of human carcinoma cell lines is induced by the tumor microenvironment
Q36293908	SIRT1 is involved in oncogenic signaling mediated by GPER in breast cancer.
Q52841133	SOCS1 inhibits migration and invasion of prostate cancer cells, attenuates tumor growth and modulates the tumor stroma.
Q42831528	SPARC enhances tumor stroma formation and prevents fibroblast activation
Q37337322	SPARCL1 suppresses metastasis in prostate cancer.
Q30849602	STAT3 can be activated through paracrine signaling in breast epithelial cells
Q36169762	STAT3-mediated IGF-2 secretion in the tumour microenvironment elicits innate resistance to anti-IGF-1R antibody
Q64987986	Salivary Glycine Is a Significant Predictor for the Attenuation of Polyp and Tumor Microenvironment Formation by Fucoxanthin in AOM/DSS Mice.
Q36707153	Scaffold-Free Coculture Spheroids of Human Colonic Adenocarcinoma Cells and Normal Colonic Fibroblasts Promote Tumorigenicity in Nude Mice.
Q37583096	Sclerosing adenosis and risk of breast cancer.
Q36679133	Second harmonic generation reveals matrix alterations during breast tumor progression
Q37651981	Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity.
Q82968978	Secreted growth factors from stromal fibroblasts of the human lung and pancreatic carcinomas
Q41844791	Senescent cancer-associated fibroblasts secrete active MMP-2 that promotes keratinocyte dis-cohesion and invasion
Q38968807	Senescent stroma promotes prostate cancer progression: the role of miR-210.
Q38731737	Senescent stromal cell-induced divergence and therapeutic resistance in T cell acute lymphoblastic leukemia/lymphoma
Q39187279	Separation and cultivation of laryngeal carcinoma-associated fibroblasts and biological influence on a laryngeal carcinoma cell line
Q41193853	SerpinB2 regulates stromal remodelling and local invasion in pancreatic cancer.
Q34998455	Serum biomarkers reflecting specific tumor tissue remodeling processes are valuable diagnostic tools for lung cancer
Q57463786	Serum-derived carcinoembryonic antigen (CEA) activates fibroblasts to induce a local re-modeling of the extracellular matrix that favors the engraftment of CEA-expressing tumor cells
Q38925157	Signal transducer and activator of transcription 3 as a therapeutic target for cancer and the tumor microenvironment
Q53530314	Significance of Vascular Endothelial Growth Factor (VEGF)-C and VEGF-D in the Progression of Cutaneous Melanoma.
Q36101233	Significance of heparanase in cancer and inflammation
Q37845923	Significance of myofibroblasts in oral squamous cell carcinoma
Q36357356	Significance of tumor-associated stroma in promotion of intratumoral lymphangiogenesis: pivotal role of a hyaluronan-rich tumor microenvironment
Q30412034	Silencing of miR-148a in cancer-associated fibroblasts results in WNT10B-mediated stimulation of tumor cell motility
Q41871186	Silibinin inhibits fibronectin induced motility, invasiveness and survival in human prostate carcinoma PC3 cells via targeting integrin signaling
Q33687149	Simulating tumor microenvironment: changes in protein expression in an in vitro co-culture system
Q87852511	Simultaneous analysis of the gene expression profiles of cancer and stromal cells in endometrial cancer
Q51361969	Simultaneous blocking of IL-6 and IL-8 is sufficient to fully inhibit CAF-induced human melanoma cell invasiveness.
Q90179380	Single Tumor Cells With Epithelial-Like Morphology Are Associated With Breast Cancer Metastasis
Q42373073	Single cell dual adherent-suspension co-culture micro-environment for studying tumor-stromal interactions with functionally selected cancer stem-like cells
Q38886389	Single cell migration in oral squamous cell carcinoma - possible evidence of epithelial-mesenchymal transition in vivo
Q40110840	Single-chain Fv immunoliposomes for the targeting of fibroblast activation protein-expressing tumor stromal cells
Q50533003	Sipa1 deficiency unleashes a host-immune mechanism eradicating chronic myelogenous leukemia-initiating cells.
Q41957111	Sirtuin 1 suppresses nuclear factor κB induced transactivation and pro-inflammatory cytokine expression in cat fibroblast cells
Q57385040	Skin Cell Heterogeneity in Development, Wound Healing, and Cancer
Q42677551	Skin transcriptome reveals the intrinsic molecular mechanisms underlying hair follicle cycling in Cashmere goats under natural and shortened photoperiod conditions
Q52341066	Small proline-rich protein 2B drives stress-dependent p53 degradation and fibroblast proliferation in heart failure.
Q37726232	Small role with big impact: miRNAs as communicators in the cross-talk between cancer-associated fibroblasts and cancer cells
Q57664399	Smooth muscle actin-expressing stromal fibroblasts in head and neck squamous cell carcinoma: Increased expression of galectin-1 and induction of poor prognosis factors
Q42288796	Snail suppresses cellular senescence and promotes fibroblast-led cancer cell invasion
Q34503198	Somatic cell plasticity and Niemann-Pick type C2 protein: fibroblast activation
Q37575859	Sox10+ adult stem cells contribute to biomaterial encapsulation and microvascularization
Q49391559	Spatial and single-cell transcriptional profiling identifies functionally distinct human dermal fibroblast subpopulations.
Q26774121	Special cancer microenvironment in human colonic cancer: Concept of cancer microenvironment formed by peritoneal invasion (CMPI) and implication of subperitoneal fibroblast in cancer progression
Q37183172	Specific glycosphingolipids mediate epithelial-to-mesenchymal transition of human and mouse epithelial cell lines
Q33626567	Specific protein and miRNA patterns characterise tumour-associated fibroblasts in bladder cancer
Q38856698	Specific upregulation of RHOA and RAC1 in cancer-associated fibroblasts found at primary tumor and lymph node metastatic sites in breast cancer
Q39029861	Spheroid formation and invasion capacity are differentially influenced by co-cultures of fibroblast and macrophage cells in breast cancer.
Q36782379	Sphingosine kinase 1 is required for TGF-β mediated fibroblastto- myofibroblast differentiation in ovarian cancer.
Q36767279	Src-mediated morphology transition of lung cancer cells in three-dimensional organotypic culture.
Q30487084	Staged stromal extracellular 3D matrices differentially regulate breast cancer cell responses through PI3K and beta1-integrins
Q84911206	Starting the scar: a primary role for pericytes?
Q42328088	Stiffened Extracellular Matrix and Signaling from Stromal Fibroblasts via Osteoprotegerin Regulate Tumor Cell Invasion in a 3-D Tumor in Situ Model.
Q44784893	Stochastic modelling of biased cell migration and collagen matrix modification
Q41045204	Stochastic multi-scale models of competition within heterogeneous cellular populations: Simulation methods and mean-field analysis.
Q38125197	Strategies to increase drug penetration in solid tumors
Q35062322	Stretching fibroblasts remodels fibronectin and alters cancer cell migration
Q39310184	Stroma-directed imatinib therapy impairs the tumor-promoting effect of bone marrow-derived mesenchymal stem cells in an orthotopic transplantation model of colon cancer
Q37148199	Stroma-directed molecular targeted therapy in gastric cancer
Q37214284	Stromal Activation by Tumor Cells: An in Vitro Study in Breast Cancer
Q34581844	Stromal CD10 and SPARC expression in ductal carcinoma in situ (DCIS) patients predicts disease recurrence
Q35666119	Stromal Expression of Fibroblast Activation Protein Alpha (FAP) Predicts Platinum Resistance and Shorter Recurrence in patients with Epithelial Ovarian Cancer
Q35962304	Stromal Integrin α11β1 Affects RM11 Prostate and 4T1 Breast Xenograft Tumors Differently
Q34810329	Stromal LRP1 in lung adenocarcinoma predicts clinical outcome
Q47373003	Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway.
Q33714718	Stromal PDGFR-α Activation Enhances Matrix Stiffness, Impedes Mammary Ductal Development, and Accelerates Tumor Growth.
Q60045514	Stromal PTEN Regulates Extracellular Matrix Organization in the Mammary Gland
Q61136284	Stromal PTEN determines mammary epithelial response to radiotherapy
Q41767315	Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1
Q26774497	Stromal Targets for Fluorescent-Guided Oncologic Surgery
Q35068998	Stromal alterations as quantitative optical biomarkers of epithelial tumor progression
Q42700193	Stromal and epithelial networks: Temporal gene expression profiling during invasive neoplasia
Q38494338	Stromal biology and therapy in pancreatic cancer: a changing paradigm
Q38017601	Stromal biomarkers in breast cancer development and progression
Q48009734	Stromal cell cadherin-11 regulates adipose tissue inflammation and diabetes.
Q55016792	Stromal cells in breast cancer as a potential therapeutic target.
Q35609967	Stromal cells in tumor microenvironment and breast cancer
Q83770207	Stromal cells modulate TCL1 expression, interacting AP-1 components and TCL1-targeting micro-RNAs in chronic lymphocytic leukemia
Q42273036	Stromal control of oncogenic traits expressed in response to the overexpression of GLI2, a pleiotropic oncogene
Q84364466	Stromal expression of CD34, α-smooth muscle actin and CD26/DPPIV in squamous cell carcinoma of the skin: a comparative immunohistochemical study
Q42316344	Stromal expression of Fer suppresses tumor progression in renal cell carcinoma and is a predictor of survival
Q34374236	Stromal expression of decorin, Semaphorin6D, SPARC, Sprouty1 and Tsukushi in developing prostate and decreased levels of decorin in prostate cancer
Q35202991	Stromal expression of heat-shock protein 27 is associated with worse clinical outcome in patients with colorectal cancer lung metastases
Q83327370	Stromal expression of vascular endothelial growth factor C is relevant to predict sentinel lymph node status in melanomas
Q38225334	Stromal fibroblasts and the immune microenvironment: partners in mammary gland biology and pathology?
Q34268740	Stromal fibroblasts in digestive cancer
Q34627461	Stromal fibroblasts in the microenvironment of gastric carcinomas promote tumor metastasis via upregulating TAGLN expression
Q27333747	Stromal fibroblasts mediate extracellular matrix remodeling and invasion of scirrhous gastric carcinoma cells
Q37716611	Stromal fibroblasts present in breast carcinomas promote tumor growth and angiogenesis through adrenomedullin secretion
Q33719793	Stromal genes discriminate preinvasive from invasive disease, predict outcome, and highlight inflammatory pathways in digestive cancers
Q36796966	Stromal induction of breast cancer: inflammation and invasion
Q36641872	Stromal interactions as regulators of tumor growth and therapeutic response: A potential target for photodynamic therapy?
Q36751290	Stromal miR-200s contribute to breast cancer cell invasion through CAF activation and ECM remodeling
Q54198345	Stromal miR-21 is more important than miR-21 of tumour cells for the progression of gastric cancer.
Q83381970	Stromal miR-320 keeps an oncogenic secretome in check
Q42696083	Stromal myofibroblasts accompany modifications in the epithelial phenotype of tongue dysplastic and malignant lesions
Q38402765	Stromal myofibroblasts in focal reactive overgrowths of the gingiva
Q33659120	Stromal optical properties: differentiating normal and cancerous stroma
Q50138285	Stromal resistance of fibroblasts against oxidative damage: involvement of tumor cell-secreted platelet-derived growth factor (PDGF) and phosphoinositide 3-kinase (PI3K) activation.
Q37247542	Stromal uptake and transmission of acid is a pathway for venting cancer cell-generated acid.
Q34944820	Stromal-dependent tumor promotion by MIF family members
Q48112414	Stromal-derived IGF2 promotes colon cancer progression via paracrine and autocrine mechanisms
Q61812058	Stromal-derived interleukin 6 drives epithelial-to-mesenchymal transition and therapy resistance in esophageal adenocarcinoma
Q37460975	Stromal-epithelial crosstalk provides a suitable microenvironment for the progression of ovarian cancer cells in vitro
Q37295029	Structural and ultrastructural evidence for telocytes in prostate stroma
Q38734680	Structure and Function of a Prostate Cancer Dissemination-Permissive Extracellular Matrix
Q36559850	Structure and function of glycosphingolipids and sphingolipids: recollections and future trends
Q36049145	Studying primary tumor-associated fibroblast involvement in cancer metastasis in mice
Q36372792	Suboptimal cytoreduction in ovarian carcinoma is associated with molecular pathways characteristic of increased stromal activation
Q47897668	Substrate stiffness modulates lung cancer cell migration but not epithelial to mesenchymal transition
Q36596228	Suicide Gene-Engineered Stromal Cells Reveal a Dynamic Regulation of Cancer Metastasis
Q91775763	Suppression of Stromal Interferon Signaling by Human Papillomavirus 16
Q54114273	Suppression of TGFβ-mediated conversion of endothelial cells and fibroblasts into cancer associated (myo)fibroblasts via HDAC inhibition.
Q57794781	Suppression of stromal-derived Dickkopf-3 (DKK3) inhibits tumor progression and prolongs survival in pancreatic ductal adenocarcinoma
Q38676055	Surviving at a distance: organ specific metastasis
Q35171136	Sustained β-catenin activity in dermal fibroblasts promotes fibrosis by up-regulating expression of extracellular matrix protein-coding genes
Q58861133	Synchronous collision malignant melanoma and adenocarcinoma of the rectum
Q34998315	System-wide analysis reveals a complex network of tumor-fibroblast interactions involved in tumorigenicity
Q33499686	Systems-level modeling of cancer-fibroblast interaction
Q34343664	T cells and stromal fibroblasts in human tumor microenvironments represent potential therapeutic targets
Q34105259	TAGLN expression is upregulated in NF1-associated malignant peripheral nerve sheath tumors by hypomethylation in its promoter and subpromoter regions
Q37705967	TGF-β Mediated Crosstalk Between Malignant Hepatocyte and Tumor Microenvironment in Hepatocellular Carcinoma
Q28547113	TGF-β Negatively Regulates CXCL1 Chemokine Expression in Mammary Fibroblasts through Enhancement of Smad2/3 and Suppression of HGF/c-Met Signaling Mechanisms
Q39071510	TGF-β, Bone Morphogenetic Protein, and Activin Signaling and the Tumor Microenvironment
Q28075605	TGFΒ-induced transcription in cancer
Q39519065	THBS4, a novel stromal molecule of diffuse-type gastric adenocarcinomas, identified by transcriptome-wide expression profiling
Q92123390	TLRs in pulmonary diseases
Q41485983	TRAF4 promotes lung cancer aggressiveness by modulating tumor microenvironment in normal fibroblasts
Q38203918	TRP channels and STIM/ORAI proteins: sensors and effectors of cancer and stroma cell migration
Q34832513	TSPAN12 is a critical factor for cancer-fibroblast cell contact-mediated cancer invasion
Q33403396	Tamoxifen induces pleiotrophic changes in mammary stroma resulting in extracellular matrix that suppresses transformed phenotypes
Q37862154	Tangled fibroblasts in tumor-stroma interactions
Q36056206	Targeted Mesoporous Iron Oxide Nanoparticles-Encapsulated Perfluorohexane and a Hydrophobic Drug for Deep Tumor Penetration and Therapy
Q52579251	Targeting Accessories to the Crime: Nanoparticle Nucleic Acid Delivery to the Tumor Microenvironment.
Q35760031	Targeting Matrix Metalloproteinases in Cancer: Bringing New Life to Old Ideas
Q39434606	Targeting PDGFR-β in Cholangiocarcinoma
Q26769963	Targeting Stromal-Cancer Cell Crosstalk Networks in Ovarian Cancer Treatment
Q33513307	Targeting TNF-alpha for cancer therapy
Q89667670	Targeting cancer stem cell pathways for cancer therapy
Q36187424	Targeting chemokine pathways in esophageal adenocarcinoma
Q36414357	Targeting chemotherapy-induced PTX3 in tumor stroma to prevent the progression of drug-resistant cancers
Q36685345	Targeting colorectal cancer via its microenvironment by inhibiting IGF-1 receptor-insulin receptor substrate and STAT3 signaling
Q37452281	Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice
Q36730567	Targeting inhibition of fibroblast activation protein-α and prolyl oligopeptidase activities on cells common to metastatic tumor microenvironments
Q34547374	Targeting metastasis-initiating cells through the fatty acid receptor CD36
Q28067219	Targeting microenvironment in cancer therapeutics
Q50159459	Targeting nuclear receptors in cancer-associated fibroblasts as concurrent therapy to inhibit development of chemoresistant tumors.
Q36624058	Targeting of cancer‑associated fibroblasts enhances the efficacy of cancer chemotherapy by regulating the tumor microenvironment
Q47961293	Targeting senescent cholangiocytes and activated fibroblasts with B-cell lymphoma-extra large inhibitors ameliorates fibrosis in multidrug resistance 2 gene knockout (Mdr2-/- ) mice.
Q38852121	Targeting stromal-induced pyruvate kinase M2 nuclear translocation impairs oxphos and prostate cancer metastatic spread.
Q92652651	Targeting the Interplay Between Cancer Fibroblasts, Mesenchymal Stem Cells, and Cancer Stem Cells in Desmoplastic Cancers
Q58789499	Targeting the Microenvironment in High Grade Serous Ovarian Cancer
Q42145272	Targeting the adventitial microenvironment in pulmonary hypertension: A potential approach to therapy that considers epigenetic change
Q37686160	Targeting the cancer-associated fibroblasts as a treatment in triple-negative breast cancer
Q36626921	Targeting the tumour microenvironment in ovarian cancer
Q37391029	Targeting the tumour stroma to increase efficacy of chemo- and radiotherapy
Q37767356	Targeting the tumour vasculature: insights from physiological angiogenesis
Q48308048	Targeting tumor microenvironment to curb chemoresistance via novel drug delivery strategies.
Q53307716	Targeting tumor-stroma crosstalk: the example of the NT157 inhibitor.
Q49887906	Targeting tumour microenvironment by tyrosine kinase inhibitor.
Q37008387	Telomere attrition in cancer cells and telomere length in tumor stroma cells predict chromosome instability in esophageal squamous cell carcinoma: a genome-wide analysis
Q33694568	Tenascin-W is a specific marker of glioma-associated blood vessels and stimulates angiogenesis in vitro
Q35858640	Texture Analysis of Non-Contrast-Enhanced Computed Tomography for Assessing Angiogenesis and Survival of Soft Tissue Sarcoma
Q64060659	The 1ALCTL and 1BLCTL isoforms of Arg/Abl2 induce fibroblast activation and extra cellular matrix remodelling differently
Q34121796	The 5-HT(2B) receptor plays a key regulatory role in both neuroendocrine tumor cell proliferation and the modulation of the fibroblast component of the neoplastic microenvironment
Q37008870	The Action of Discoidin Domain Receptor 2 in Basal Tumor Cells and Stromal Cancer-Associated Fibroblasts Is Critical for Breast Cancer Metastasis.
Q38586078	The Amazing Power of Cancer Cells to Recapitulate Extraembryonic Functions: The Cuckoo's Tricks.
Q52914635	The Antiaging Properties of Andrographis paniculata by Activation Epidermal Cell Stemness.
Q35894249	The Arp2/3 complex is required for lamellipodia extension and directional fibroblast cell migration
Q50579985	The Binding Site Barrier Elicited by Tumor-Associated Fibroblasts Interferes Disposition of Nanoparticles in Stroma-Vessel Type Tumors.
Q92712560	The Dark Side of Fibroblasts: Cancer-Associated Fibroblasts as Mediators of Immunosuppression in the Tumor Microenvironment
Q90041289	The Diagnostic Significance of PDGF, EphA7, CCR5, and CCL5 Levels in Colorectal Cancer
Q36507002	The Effect of Stromal Integrin β3-Deficiency on Two Different Tumors in Mice
Q41775545	The Effect of Tumor Microenvironment on Autophagy and Sensitivity to Targeted Therapy in EGFR-Mutated Lung Adenocarcinoma.
Q58093770	The Emerging Role of the Microenvironment in Endometrial Cancer
Q38636468	The Emerging Roles of Extracellular Vesicles As Communication Vehicles within the Tumor Microenvironment and Beyond
Q92594835	The Evolving Field of Stereotactic Body Radiation Therapy in Pancreatic Cancer
Q58784339	The Expression Levels of IL-4/IL-13/STAT6 Signaling Pathway Genes and SOCS3 Could Help to Differentiate the Histopathological Subtypes of Non-Small Cell Lung Carcinoma
Q33361929	The Extracellular Matrix in Epithelial Ovarian Cancer - A Piece of a Puzzle
Q33838714	The Functions of MicroRNA-200 Family in Ovarian Cancer: Beyond Epithelial-Mesenchymal Transition
Q35818450	The HSP90 Inhibitor Ganetespib Radiosensitizes Human Lung Adenocarcinoma Cells
Q64927223	The IL-1/IL-1R axis induces greater fibroblast-derived chemokine release in human papillomavirus-negative compared to positive oropharyngeal cancer.
Q90133583	The Immune Microenvironment of Breast Cancer Progression
Q54942438	The Impact of Radiation on the Tumor Microenvironment: Effect of Dose and Fractionation Schedules.
Q36761574	The Initiator Methionine tRNA Drives Secretion of Type II Collagen from Stromal Fibroblasts to Promote Tumor Growth and Angiogenesis
Q40444191	The Interaction Between Human Papillomaviruses and the Stromal Microenvironment
Q26783022	The Mesothelial Origin of Carcinoma Associated-Fibroblasts in Peritoneal Metastasis
Q54236409	The Microenvironment in Epstein-Barr Virus-Associated Malignancies.
Q38679301	The Microenvironment of Lung Cancer and Therapeutic Implications
Q90140513	The Milk Protein Alpha-Casein Suppresses Triple Negative Breast Cancer Stem Cell Activity Via STAT and HIF-1alpha Signalling Pathways in Breast Cancer Cells and Fibroblasts
Q97537884	The Mini-Organo: A rapid high-throughput 3D coculture organotypic assay for oncology screening and drug development
Q37876782	The Nyhus-Wantz lectureship: etiology, herniosis, diverticulosis coli, and cancer
Q37758303	The Oncogenic Potential of Mesenchymal Stem Cells in the Treatment of Cancer: Directions for Future Research
Q92230700	The Role of Autophagy in Cancer
Q92923287	The Role of Bone Morphogenetic Protein 7 (BMP-7) in Inflammation in Heart Diseases
Q28077024	The Role of CC-Chemokines in the Regulation of Angiogenesis
Q92027212	The Role of Cancer Stem Cells and Mechanical Forces in Ovarian Cancer Metastasis
Q92509065	The Role of Exosomal MicroRNAs in the Tumor Microenvironment of Breast Cancer
Q39521033	The Role of FoxC2 Transcription Factor in Tumor Angiogenesis
Q28391620	The Role of PTEN in Tumor Angiogenesis
Q26801843	The Role of Stroma in Tumor Development
Q64923650	The Roles of YAP/TAZ and the Hippo Pathway in Healthy and Diseased Skin.
Q92799863	The Tumor Microenvironment as a Regulator of Endocrine Resistance in Breast Cancer
Q37970636	The Tumor-Promoting Flow of Cells Into, Within and Out of the Tumor Site: Regulation by the Inflammatory Axis of TNFα and Chemokines
Q40127968	The VEGF angiogenic switch of fibroblasts is regulated by MMP-7 from cancer cells
Q38112032	The adventitia: Essential role in pulmonary vascular remodeling
Q27000503	The adventitia: essential regulator of vascular wall structure and function
Q58579097	The anti-psychotic drug pimozide is a novel chemotherapeutic for breast cancer
Q38006769	The bed and the bugs: interactions between the tumor microenvironment and cancer stem cells
Q38828825	The biology and function of fibroblasts in cancer
Q37987661	The biology of personalized cancer medicine: facing individual complexities underlying hallmark capabilities
Q38767957	The brain tissue response to surgical injury and its possible contribution to glioma recurrence.
Q26824147	The cancer stem cell niche: how essential is the niche in regulating stemness of tumor cells?
Q33410394	The carboxyl terminal trimer of procollagen I induces pro-metastatic changes and vascularization in breast cancer cells xenografts
Q57188839	The contributions of cancer cell metabolism to metastasis
Q37321944	The critical role of SDF-1/CXCR4 axis in cancer and cancer stem cells metastasis.
Q37267037	The crosstalk: Tumor-infiltrating lymphocytes rich in regulatory T cells suppressed cancer-associated fibroblasts
Q33642464	The dominant role of IL-8 as an angiogenic driver in a three-dimensional physiological tumor construct for drug testing
Q92367121	The double edge sword of fibrosis in cancer
Q94563647	The double-edged sword role of fibroblasts in the interaction with cancer cells; an agent-based modeling approach
Q38210012	The double-edged sword: conserved functions of extracellular hsp90 in wound healing and cancer
Q26830787	The dynamic role of cardiac fibroblasts in development and disease
Q36459089	The effect of matrix density on the regulation of 3-D capillary morphogenesis
Q46157035	The effect of sorafenib on hepatic stellate cells: implication of its effect on tumor microenvironment
Q64097202	The effects and the mechanisms of autophagy on the cancer-associated fibroblasts in cancer
Q37418330	The effects of CA IX catalysis products within tumor microenvironment.
Q34226670	The efficacy of a novel, dual PI3K/mTOR inhibitor NVP-BEZ235 to enhance chemotherapy and antiangiogenic response in pancreatic cancer
Q38129921	The endothelin axis in head and neck cancer: a promising therapeutic opportunity?
Q37673528	The epithelial to mesenchymal transition (EMT) and cancer stem cells: implication for treatment resistance in pancreatic cancer
Q59789307	The epithelial-to-mesenchymal transition induced by tumor-associated macrophages confers chemoresistance in peritoneally disseminated pancreatic cancer
Q39987977	The essential role of fibroblasts in esophageal squamous cell carcinoma-induced angiogenesis
Q28079015	The ever-expanding role of HIF in tumour and stromal biology
Q86940390	The evolution of the cancer niche during multistage carcinogenesis
Q59134962	The evolving relationship of wound healing and tumor stroma
Q36181412	The expression pattern of matrix-producing tumor stroma is of prognostic importance in breast cancer
Q37948581	The extent of retraction clefts correlates with lymphatic vessel density and VEGF-C expression and predicts nodal metastasis and poor prognosis in early-stage breast carcinoma
Q39856408	The extracellular matrix glycoprotein elastin microfibril interface located protein 2: a dual role in the tumor microenvironment
Q37826353	The extracellular matrix in digestive cancer
Q33796058	The fibroblast integrin alpha11beta1 is induced in a mechanosensitive manner involving activin A and regulates myofibroblast differentiation
Q36841980	The fibromatosis signature defines a robust stromal response in breast carcinoma
Q33864284	The footprint of the ageing stroma in older patients with breast cancer
Q29615536	The functions and regulation of the PTEN tumour suppressor
Q36391951	The hallmarks of cancer: a long non-coding RNA point of view.
Q36545542	The herbal compound Songyou Yin (SYY) inhibits hepatocellular carcinoma growth and improves survival in models of chronic fibrosis via paracrine inhibition of activated hepatic stellate cells
Q38896944	The hypoxic microenvironment: A determinant of cancer stem cell evolution
Q84127499	The impact of caveolin protein expression in tumor stroma on prognosis of breast cancer
Q37933095	The inflammatory tumor microenvironment, epithelial mesenchymal transition and lung carcinogenesis
Q27333738	The influence of electric field and confinement on cell motility
Q91865980	The interplay between intrinsic and extrinsic Wnt signaling in controlling intestinal transformation
Q35868405	The interplay of extracellular matrix and microbiome in urothelial bladder cancer
Q47624410	The involvement of lncRNAs in the development and progression of pancreatic cancer
Q93013140	The life cycle of cancer-associated fibroblasts within the tumour stroma and its importance in disease outcome
Q36251455	The matrix protein Fibulin-5 is at the interface of tissue stiffness and inflammation in fibrosis
Q37849666	The mechanisms of cancer immunoescape and development of overcoming strategies
Q46304569	The metabolic cross-talk between epithelial cancer cells and stromal fibroblasts in ovarian cancer progression: Autophagy plays a role.
Q39911126	The metalloproteinase ADAM-12 regulates bronchial epithelial cell proliferation and apoptosis.
Q36928869	The metastatic niche: adapting the foreign soil
Q37563816	The microenvironment in mature B-cell malignancies: a target for new treatment strategies
Q39426202	The migration speed of cancer cells influenced by macrophages and myofibroblasts co-cultured in a microfluidic chip
Q38853674	The nanomechanical signature of liver cancer tissues and its molecular origin
Q34291977	The need for complex 3D culture models to unravel novel pathways and identify accurate biomarkers in breast cancer
Q39366753	The pancreatic cancer microenvironment: A true double agent.
Q92242397	The paracrine effects of fibroblasts on Doxorubicin-treated breast cancer cells
Q36905454	The paracrine hormone hypothesis of colorectal cancer.
Q84975992	The parallel lives of angiogenesis and immunosuppression: cancer and other tales
Q35291689	The polyphenols (-)-epigallocatechin-3-gallate and luteolin synergistically inhibit TGF-β-induced myofibroblast phenotypes through RhoA and ERK inhibition
Q38204343	The potential role of HIF on tumour progression and dissemination.
Q35931795	The pro-metastatic role of bone marrow-derived cells: a focus on MSCs and regulatory T cells
Q33779031	The prognostic significance of cancer-associated fibroblasts in esophageal squamous cell carcinoma
Q90327752	The prognostic significance of carcinoma-associated fibroblasts and tumor-associated macrophages in nasopharyngeal carcinoma
Q35870502	The prognostic significance of tumour-stroma ratio in endometrial carcinoma
Q48634875	The renal (myo-)fibroblast: a heterogeneous group of cells.
Q34599918	The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy
Q35133043	The role of HGF/MET and FGF/FGFR in fibroblast-derived growth stimulation and lapatinib-resistance of esophageal squamous cell carcinoma
Q28073714	The role of cancer-associated fibroblasts in esophageal cancer
Q38216639	The role of cancer-associated fibroblasts, solid stress and other microenvironmental factors in tumor progression and therapy resistance
Q38777172	The role of chemerin and ChemR23 in stimulating the invasion of squamous oesophageal cancer cells
Q38021441	The role of endothelial-mesenchymal transition in development and pathological process
Q37271443	The role of endothelial-to-mesenchymal transition in cancer progression
Q34505037	The role of epithelial plasticity in prostate cancer dissemination and treatment resistance
Q36640439	The role of human peritoneal mesothelial cells in the fibrosis and progression of gastric cancer
Q33942378	The role of mechanical forces in tumor growth and therapy
Q30429895	The role of miR-31 and its target gene SATB2 in cancer-associated fibroblasts.
Q90086637	The role of myofibroblasts in the progression of oral submucous fibrosis: A systematic review
Q38075556	The role of non-hematopoietic stromal cells in the persistence of inflammation
Q37110541	The role of palladin in actin organization and cell motility
Q38055432	The role of promoter hypermethylation in fibroblast activation and fibrogenesis
Q47807012	The role of shear stress and altered tissue properties on endothelial to mesenchymal transformation and tumor-endothelial cell interaction.
Q38063961	The role of stromal cells in the persistence of chronic inflammation
Q33703599	The role of stromal factors in breast tumorigenicity.
Q38032281	The role of stromal myofibroblast and extracellular matrix in tumor angiogenesis
Q35531372	The role of the cell-cell interactions in cancer progression
Q88779993	The role of the epithelial-to-mesenchymal transition (EMT) in diseases of the salivary glands
Q26997815	The role of the myofibroblast in tumor stroma remodeling
Q99568119	The role of the tumour microenvironment in the angiogenesis of pituitary tumours
Q38922999	The roles of tumor- and metastasis-promoting carcinoma-associated fibroblasts in human carcinomas.
Q89017919	The significance of scirrhous gastric cancer cell lines: the molecular characterization using cell lines and mouse models
Q60915495	The transcriptome landscape of the carcinogenic treatment response in the blind mole rat: insights into cancer resistance mechanisms
Q27318697	The tumor as an organ: comprehensive spatial and temporal modeling of the tumor and its microenvironment
Q37318832	The tumor microenvironment and its contribution to tumor evolution toward metastasis
Q34343645	The tumor microenvironment in colorectal carcinogenesis
Q28077074	The tumor microenvironment in esophageal cancer
Q37800217	The tumor microenvironment in hepatocellular carcinoma: current status and therapeutic targets.
Q37036957	The tumor microenvironment modulates tamoxifen resistance in breast cancer: a role for soluble stromal factors and fibronectin through β1 integrin
Q38536374	The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence
Q53338021	The tumour microenvironment as a target for chemoprevention.
Q53629802	The tumour stromal features are associated with resistance to 5-FU-based chemoradiotherapy and a poor prognosis in patients with oral squamous cell carcinoma.
Q52581537	The versatile role of exosomes in cancer progression: diagnostic and therapeutic implications.
Q30354655	Theranostic Probes for Targeting Tumor Microenvironment: An Overview.
Q36721737	Theranostic nanoparticles with controlled release of gemcitabine for targeted therapy and MRI of pancreatic cancer
Q36545163	Therapeutic effects of deleting cancer-associated fibroblasts in cholangiocarcinoma
Q42360479	Therapeutic properties of aerobic training after a cancer diagnosis: more than a one-trick pony?
Q33770035	Therapeutic strategies for targeting the ovarian tumor stroma
Q90620377	Therapeutic targeting of the crosstalk between cancer-associated fibroblasts and cancer stem cells
Q37851151	Therapeutic targeting of tumor-stroma interactions.
Q38756772	Therapy-induced microenvironmental changes in cancer
Q47282821	Thermodynamic Aspects and Reprogramming Cellular Energy Metabolism during the Fibrosis Process
Q49693689	Three-Dimensional Hepatocellular Carcinoma/Fibroblast Model on a Nanofibrous Membrane Mimics Tumor Cell Phenotypic Changes and Anticancer Drug Resistance.
Q38903329	Three-dimensional Co-culture model for tumor-stromal interaction
Q47134459	Three-dimensional organotypic matrices from alternative collagen sources as pre-clinical models for cell biology.
Q35931790	Tie1 deficiency induces endothelial-mesenchymal transition
Q39496546	Time-dependent micromechanical responses of breast cancer cells and adjacent fibroblasts to electric treatment
Q50133270	Tissue analyses reveal a potential immune-adjuvant function of FAP-1 positive fibroblasts in non-small cell lung cancer.
Q42317488	Tissue and imaging biomarkers for hypoxia predict poor outcome in endometrial cancer
Q34383988	Tissue injury and hypoxia promote malignant progression of prostate cancer by inducing CXCL13 expression in tumor myofibroblasts
Q37956221	Tissue transglutaminase, inflammation, and cancer: how intimate is the relationship?
Q26851658	Trabectedin and plitidepsin: drugs from the sea that strike the tumor microenvironment
Q58770422	Tracing the path of cancer initiation: the AA protein-based model for cancer genesis
Q36319389	Tracking miRNAs' footprints in tumor-microenvironment interactions: Insights and implications for targeted cancer therapy
Q36695058	Transcription factor networks in invasion-promoting breast carcinoma-associated fibroblasts
Q42153424	Transcriptional profile of fibroblasts obtained from the primary site, lymph node and bone marrow of breast cancer patients
Q36007057	Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks
Q37269535	Transcriptional regulation of tenascin-W by TGF-beta signaling in the bone metastatic niche of breast cancer cells
Q30664746	Transfer of mitochondria via tunneling nanotubes rescues apoptotic PC12 cells
Q36531166	Transformable Peptide Nanocarriers for Expeditious Drug Release and Effective Cancer Therapy via Cancer-Associated Fibroblast Activation.
Q51776900	Transformed epithelial cells and fibroblasts/myofibroblasts interaction in breast tumor: a mathematical model and experiments.
Q38766773	Transforming Growth Factor β1 Promotes Migration and Invasion of Human Hepatocellular Carcinoma Cells Via Up-Regulation of Connective Tissue Growth Factor
Q60620985	Transforming growth factor-β modulates pancreatic cancer associated fibroblasts cell shape, stiffness and invasion
Q34982720	Transgenic expression of polyomavirus middle T antigen in the mouse prostate gives rise to carcinoma
Q34994693	Transglutaminase 2 overexpression in tumor stroma identifies invasive ductal carcinomas of breast at high risk of recurrence
Q37981102	Transglutaminases: key regulators of cancer metastasis.
Q30497815	Translating tumor biology into personalized treatment planning: analytical performance characteristics of the Oncotype DX Colon Cancer Assay
Q89587297	Translational Landscape of mTOR Signaling in Integrating Cues Between Cancer and Tumor Microenvironment
Q38858806	Translational aspects in targeting the stromal tumour microenvironment: from bench to bedside.
Q35219539	Translational horizons in the tumor microenvironment: harnessing breakthroughs and targeting cures
Q37040712	Transplantation of iPSC-derived TM cells rescues glaucoma phenotypes in vivo.
Q36241046	Treatment of breast cancer stem cells with oncolytic herpes simplex virus
Q37106988	Triggering the landslide: The tumor-promotional effects of myofibroblasts
Q90040642	Triple-Negative Breast Cancer: Current Understanding and Future Therapeutic Breakthrough Targeting Cancer Stemness
Q35646453	Tumor Interstitial Fluid Formation, Characterization, and Clinical Implications
Q39141484	Tumor Microenvironment and Differential Responses to Therapy
Q98771756	Tumor Microenvironment in Ovarian Cancer: Function and Therapeutic Strategy
Q39143305	Tumor Microenvironment, a Paradigm in Hepatocellular Carcinoma Progression and Therapy
Q98291393	Tumor Microenvironment-Responsive Peptide-Based Supramolecular Drug Delivery System
Q51846287	Tumor Restrictions to Oncolytic Virus.
Q38811204	Tumor Specific Recruitment and Reprogramming of Mesenchymal Stem Cells in Tumorigenesis
Q26830901	Tumor angiogenesis and lymphangiogenesis: tumor/endothelial crosstalk and cellular/microenvironmental signaling mechanisms
Q33425253	Tumor associated stromal cells play a critical role on the outcome of the oncolytic efficacy of conditionally replicative adenoviruses
Q27027489	Tumor cell migration in complex microenvironments
Q34606502	Tumor cell-targeted delivery of nanoconjugated oligonucleotides in composite spheroids
Q39172441	Tumor fibroblast-derived epiregulin promotes growth of colitis-associated neoplasms through ERK
Q37800793	Tumor initiation and progression in hepatocellular carcinoma: risk factors, classification, and therapeutic targets
Q35624103	Tumor intrinsic subtype is reflected in cancer-adjacent tissue.
Q35838122	Tumor lymphangiogenesis as a potential therapeutic target
Q37346644	Tumor macrophages are pivotal constructors of tumor collagenous matrix.
Q55518010	Tumor matrix remodeling and novel immunotherapies: the promise of matrix-derived immune biomarkers.
Q38697619	Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium.
Q38121570	Tumor microenviroment and hepatocellular carcinoma metastasis
Q92393764	Tumor microenvironment and stroma in intestinal adenocarcinomas and associated metastases in Atlantic salmon broodfish (Salmo salar)
Q50246934	Tumor microenvironment in invasive lobular carcinoma: possible therapeutic targets.
Q35141434	Tumor microenvironment-derived proteins dominate the plasma proteome response during breast cancer induction and progression
Q37982937	Tumor microenvironment: a main actor in the metastasis process.
Q35361431	Tumor microenvironment: a new treatment target for cancer
Q30493184	Tumor necrosis factor-alpha regulates transforming growth factor-beta-dependent epithelial-mesenchymal transition by promoting hyaluronan-CD44-moesin interaction.
Q42371988	Tumor reactive stroma in cholangiocarcinoma: The fuel behind cancer aggressiveness.
Q35750139	Tumor signaling to the bone marrow changes the phenotype of monocytes and pulmonary macrophages during urethane-induced primary lung tumorigenesis in A/J mice
Q27015980	Tumor stroma as targets for cancer therapy
Q35765454	Tumor stroma derived biomarkers in cancer
Q36300899	Tumor stroma with senescence-associated secretory phenotype in steatohepatitic hepatocellular carcinoma.
Q41789360	Tumor suppression by stromal TIMPs
Q91650496	Tumor suppressor HIC1 is synergistically compromised by cancer-associated fibroblasts and tumor cells through the IL-6/pSTAT3 axis in breast cancer
Q41061574	Tumor talk: understanding the conversation between the tumor and its microenvironment
Q37800110	Tumor vasculature as target for therapeutic intervention.
Q35862799	Tumor-Promoting Desmoplasia Is Disrupted by Depleting FAP-Expressing Stromal Cells.
Q37086710	Tumor-associated fibroblasts predominantly come from local and not circulating precursors
Q36903707	Tumor-associated fibroblasts promote the proliferation and decrease the doxorubicin sensitivity of liposarcoma cells.
Q39268764	Tumor-associated fibrosis as a regulator of tumor immunity and response to immunotherapy.
Q37063911	Tumor-associated macrophages and stromal TNF-α regulate collagen structure in a breast tumor model as visualized by second harmonic generation.
Q37148134	Tumor-associated macrophages as incessant builders and destroyers of the cancer stroma
Q30372640	Tumor-associated macrophages of the M2 phenotype contribute to progression in gastric cancer with peritoneal dissemination.
Q92092602	Tumor-associated macrophages promote ovarian cancer cell migration by secreting transforming growth factor beta induced (TGFBI) and tenascin C
Q37728674	Tumor-derived CXCL5 promotes human colorectal cancer metastasis through activation of the ERK/Elk-1/Snail and AKT/GSK3β/β-catenin pathways.
Q49509990	Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer.
Q90087582	Tumor-derived exosomes educate fibroblasts to promote salivary adenoid cystic carcinoma metastasis via NGF-NTRK1 pathway
Q39307587	Tumor-derived mesenchymal stem cells and orthotopic site increase the tumor initiation potential of putative mouse mammary cancer stem cells derived from MMTV-PyMT mice
Q41402133	Tumor-driven Molecular Changes in Human Mesenchymal Stromal Cells
Q42654111	Tumor-educated mesenchymal stem cells promote pro-metastatic phenotype.
Q54764898	Tumor-induced Stromal STAT1 Accelerates Breast Cancer via Deregulating Tissue Homeostasis.
Q37197484	Tumor-induced stromal reprogramming drives lymph node transformation
Q37213623	Tumor-microenvironment interactions: dangerous liaisons
Q89561456	Tumor-on-a-chip for integrating a 3D tumor microenvironment: chemical and mechanical factors
Q37324753	Tumor-secreted LOXL2 activates fibroblasts through FAK signaling
Q35184789	Tumor-specific expression and alternative splicing of the COL6A3 gene in pancreatic cancer
Q39450414	Tumor-stroma interactions a trademark for metastasis
Q58799845	Tumor-stroma interactions differentially alter drug sensitivity based on the origin of stromal cells
Q36261787	Tumor-stroma ratio is an independent predictor for survival in NSCLC.
Q37955892	Tumor-stroma: In vivo assays and intravital imaging to study cell migration and metastasis
Q38968257	Tumor-α9β1 integrin-mediated signaling induces breast cancer growth and lymphatic metastasis via the recruitment of cancer-associated fibroblasts
Q30495528	Tumors as organs: complex tissues that interface with the entire organism
Q26765895	Tumour Cell Heterogeneity
Q36527927	Tumour cell-derived Wnt7a recruits and activates fibroblasts to promote tumour aggressiveness
Q37363554	Tumour cells down-regulate CCN2 gene expression in co-cultured fibroblasts in a Smad7- and ERK-dependent manner.
Q29617359	Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion
Q26766468	Tumour progression and metastasis
Q33698636	Tumour stromal cells derived from paediatric malignancies display MSC-like properties and impair NK cell cytotoxicity
Q38164308	Tumour suppressor gene function in carcinoma-associated fibroblasts: from tumour cells via EMT and back again?
Q38998166	Tumour-associated mesenchymal stem/stromal cells: emerging therapeutic targets.
Q52841791	Tumour-microenvironment interactions: role of tumour stroma and proteins produced by cancer-associated fibroblasts in chemotherapy response.
Q37507440	Tumour-site-dependent expression profile of angiogenic factors in tumour-associated stroma of primary colorectal cancer and metastases.
Q37174369	Tumour-stroma interactions in colorectal cancer: converging on beta-catenin activation and cancer stemness
Q93336606	Turning foes to friends: targeting cancer-associated fibroblasts
Q33990838	Twist and snai1 expression in pharyngeal squamous cell carcinoma stroma is related to cancer progression
Q42685028	Twist1 contributes to cranial bone initiation and dermal condensation by maintaining Wnt signaling responsiveness
Q33997938	Twist1 is up-regulated in gastric cancer-associated fibroblasts with poor clinical outcomes.
Q36186532	TβRIII Expression in Human Breast Cancer Stroma and the Role of Soluble TβRIII in Breast Cancer Associated Fibroblasts
Q26852398	Understanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironment
Q27024041	Understanding the role of stromal fibroblasts in cancer progression
Q37948053	Understanding tumor-stroma interplays for targeted therapies by armed mesenchymal stromal progenitors: the Mesenkillers
Q37802195	Understanding wild-type and mutant p53 activities in human cancer: new landmarks on the way to targeted therapies
Q36410426	Unique cellular interactions between pancreatic cancer cells and the omentum
Q36226867	Unlike pancreatic cancer cells pancreatic cancer associated fibroblasts display minimal gene induction after 5-aza-2'-deoxycytidine
Q28473677	Unraveling the microenvironmental influences on the normal mammary gland and breast cancer
Q38786015	Unravelling the relationship between macroautophagy and mitochondrial ROS in cancer therapy
Q42272472	Unveiling the role of tumor reactive stroma in cholangiocarcinoma: an opportunity for new therapeutic strategies
Q58760425	Updates on the hepatocyte growth factor/c-Met axis in hepatocellular carcinoma and its therapeutic implications
Q36719083	Upregulated Neuro-oncological Ventral Antigen 1 (NOVA1) Expression Is Specific to Mature and Immature T- and NK-Cell Lymphomas.
Q38617601	Upregulation of cancer-associated myofibroblasts by TGF-β from scirrhous gastric carcinoma cells
Q42119412	Urokinase plasminogen activator secreted by cancer-associated fibroblasts induces tumor progression via PI3K/AKT and ERK signaling in esophageal squamous cell carcinoma.
Q38109107	Using functional nanomaterials to target and regulate the tumor microenvironment: diagnostic and therapeutic applications
Q38984111	Using real-time impedance-based assays to monitor the effects of fibroblast-derived media on the adhesion, proliferation, migration and invasion of colon cancer cells.
Q37618011	VEGF blockade enhances the antitumor effect of BRAFV600E inhibition.
Q34149273	VEGF-independent angiogenic pathways induced by PDGF-C.
Q28385088	Validated prediction of pro-invasive growth factors using a transcriptome-wide invasion signature derived from a complex 3D invasion assay
Q38247284	Value of caveolin-1 in cancer progression and prognosis: Emphasis on cancer-associated fibroblasts, human cancer cells and mechanism of caveolin-1 expression (Review).
Q37527128	Varying effects of EGF, HGF and TGFβ on formation of invadopodia and invasiveness of melanoma cell lines of different origin
Q92257481	Vascularized Microfluidics and the Blood-Endothelium Interface
Q42011268	Vasodilator-stimulated phosphoprotein promotes activation of hepatic stellate cells by regulating Rab11-dependent plasma membrane targeting of transforming growth factor beta receptors
Q39285839	Vinorelbine inhibits angiogenesis and 95D migration via reducing hypoxic fibroblast stromal cell-derived factor 1 secretion
Q34253198	Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy
Q47139553	Vulvar squamous cell carcinoma aggressiveness is associated with differential expression of collagen and STAT1.
Q35884610	Warburg meets autophagy: cancer-associated fibroblasts accelerate tumor growth and metastasis via oxidative stress, mitophagy, and aerobic glycolysis
Q38922402	Whole-Organism Cellular Pathology: A Systems Approach to Phenomics.
Q29614274	Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression
Q36555217	Wnt signaling in skin development, homeostasis, and disease
Q39053166	Wnt-expressing cells in the intestines: guides for tissue remodeling
Q34542869	Wound healing and blastema formation in regenerating digit tips of adult mice.
Q26828560	Wounds that will not heal: pervasive cellular reprogramming in cancer
Q43643304	YAP forces fibroblasts to feel the tension
Q59792731	YAP/TAZ Signaling as a Molecular Link between Fibrosis and Cancer
Q40171088	ZEB1-regulated inflammatory phenotype in breast cancer cells
Q53680625	[Carcinoma-associated fibroblasts in cancer: the great escape].
Q53536050	[Tumour-stroma interactions in urothelial cancer].
Q37396605	c-Ski activates cancer-associated fibroblasts to regulate breast cancer cell invasion
Q36557492	miR-146b-5p mediates p16-dependent repression of IL-6 and suppresses paracrine procarcinogenic effects of breast stromal fibroblasts
Q37086079	miR-155-5p inhibition promotes the transition of bone marrow mesenchymal stem cells to gastric cancer tissue derived MSC-like cells via NF-κB p65 activation
Q37593531	miR-205 hinders the malignant interplay between prostate cancer cells and associated fibroblasts
Q55340090	miR-221 stimulates breast cancer cells and cancer-associated fibroblasts (CAFs) through selective interference with the A20/c-Rel/CTGF signaling.
Q53218512	miR-27 is associated with chemoresistance in esophageal cancer through transformation of normal fibroblasts to cancer-associated fibroblasts.
Q45137895	miR-29b moulds the tumour microenvironment to repress metastasis
Q59793155	miR-338-3p Is Regulated by Estrogens through GPER in Breast Cancer Cells and Cancer-Associated Fibroblasts (CAFs)
Q64059124	miR-494 induces EndMT and promotes the development of HCC (Hepatocellular Carcinoma) by targeting SIRT3/TGF-β/SMAD signaling pathway
Q54975654	miR200-regulated CXCL12β promotes fibroblast heterogeneity and immunosuppression in ovarian cancers.
Q27025496	miRNA Deregulation in Cancer Cells and the Tumor Microenvironment
Q37452957	microRNA-mediated regulation of the tumor microenvironment
Q38213075	microRNAs in the tumor microenvironment: solving the riddle for a better diagnostics
Q36921242	p16(INK4A) represses the paracrine tumor-promoting effects of breast stromal fibroblasts.
Q84074778	p21/waf1 and smooth-muscle actin α expression in stromal fibroblasts of oral cancers
Q34356907	p38 MAPK inhibits breast cancer metastasis through regulation of stromal expansion.
Q34393678	p53 status in stromal fibroblasts modulates tumor growth in an SDF1-dependent manner.
Q28541398	uPARAP function in cutaneous wound repair
Q39210673	β-adrenoceptors are upregulated in human melanoma and their activation releases pro-tumorigenic cytokines and metalloproteases in melanoma cell lines

review article	Q7318358
scholarly article	Q13442814

P6179	Dimensions Publication ID	1036672274
P356	DOI	10.1038/NRC1877
P3181	OpenCitations bibliographic resource ID	100268
P698	PubMed publication ID	16572188

P50	author	Raghu Kalluri	Q29841277
P2093	author name string	Michael Zeisberg
P2860	cites work	The Hallmarks of Cancer	Q221226
		Epithelial-mesenchymal transition and its implications for fibrosis	Q24302042
		The discoidin domain receptor tyrosine kinases are activated by collagen	Q24313329
		Endostatin: an endogenous inhibitor of angiogenesis and tumor growth	Q24315369
		Pituitary extracts and steroid hormones in the control of 3T3 cell growth	Q24562948
		Stromal effects on mammary gland development and breast cancer	Q24645558
		Inflammation and cancer	Q24649640
		Prognostic significance of tenascin-C expression in superficial and invasive bladder cancer	Q24672629
		Intermediate-sized filaments of human endothelial cells	Q24681997
		Multistep tumorigenesis and the microenvironment	Q24794552
		Distribution of vimentin and desmin filaments in smooth muscle tissue of mammalian and avian aorta	Q58439455
		Occurrence of a fetal fibroblast phenotype in familial breast cancer	Q59289731
		Smooth-muscle differentiation in stromal cells of malignant and non-malignant breast tissues	Q60305997
		Collagen proline hydroxylase in wound healing, granuloma formation, scurvy, and growth	Q68713006
		Characterization of human renal fibroblasts in health and disease: I. Immunophenotyping of cultured tubular epithelial cells and fibroblasts derived from kidneys with histologically proven interstitial fibrosis	Q70174120
		Fibroblasts from patients with breast cancer show abnormal migratory behaviour in vitro	Q72589391
		A novel model to study renal myofibroblast formation in vitro	Q73419703
		Tumor-dependent activation of rodent hepatic stellate cells during experimental melanoma metastasis	Q73712026
		Recombinant human relaxin in the treatment of scleroderma. A randomized, double-blind, placebo-controlled trial	Q73849049
		Bone-marrow-derived myofibroblasts contribute to the cancer-induced stromal reaction	Q73873891
		Tumor induction of VEGF promoter activity in stromal cells	Q77349243
		Elevated concentrations of serum relaxin are associated with metastatic disease in breast cancer patients	Q80586556
		TGF-beta and cancer	Q81484456
		Myofibroblasts in human granulation tissue	Q93754314
		Transplacental carcinogenesis by stilbestrol	Q95784569
		Deletion of integrin alpha 1 by homologous recombination permits normal murine development but gives rise to a specific deficit in cell adhesion.	Q52201902
		Characterization of human renal fibroblasts in health and disease: II. In vitro growth, differentiation, and collagen synthesis of fibroblasts from kidneys with interstitial fibrosis.	Q52236634
		Epithelial/mesenchymal interactions and branching morphogenesis of the lung.	Q52565573
		Combined total genome loss of heterozygosity scan of breast cancer stroma and epithelium reveals multiplicity of stromal targets.	Q53364039
		Differential transplantability of tumor-associated stromal cells.	Q53886677
		Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas	Q57591220
		Host microenvironment in breast cancer development: extracellular matrix-stromal cell contribution to neoplastic phenotype of epithelial cells in the breast	Q24803379
		Epithelial-mesenchymal transitions in tumour progression	Q27860487
		Integrins: versatility, modulation, and signaling in cell adhesion	Q27860844
		Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing	Q28131793
		Bone morphogenic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models	Q28201247
		Myofibroblasts and mechano-regulation of connective tissue remodelling	Q28216468
		Tumor cell interactions with the extracellular matrix during invasion and metastasis	Q28258256
		Human alpha1 type IV collagen NC1 domain exhibits distinct antiangiogenic activity mediated by alpha1beta1 integrin	Q28271413
		FAPalpha, a surface peptidase expressed during wound healing, is a tumor suppressor	Q28513202
		Vascular endothelial growth factor is a secreted angiogenic mitogen	Q28646475
		Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion	Q29547317
		Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo	Q29614729
		TGF-beta signaling in tumor suppression and cancer progression	Q29615427
		Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer	Q29616379
		Evidence that fibroblasts derive from epithelium during tissue fibrosis	Q29616581
		Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid	Q29617640
		Stromal fibroblasts in cancer initiation and progression	Q29618873
		TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia	Q29618875
		Friends or foes - bipolar effects of the tumour stroma in cancer	Q29619348
		Basement membranes: structure, assembly and role in tumour angiogenesis	Q29622882
		An overview of epithelio-mesenchymal transformation	Q30014826
		Genetic alterations in the peritumoral stromal cells of malignant and borderline epithelial ovarian tumors as indicated by allelic imbalance on chromosome 3p.	Q33197201
		Organization of fibroblasts in the heart	Q33204765
		Genomic patterns of allelic imbalance in disease free tissue adjacent to primary breast carcinomas	Q33209331
		The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis	Q33783677
		Know thy neighbor: stromal cells can contribute oncogenic signals	Q34132830
		Heterotypic signaling between epithelial tumor cells and fibroblasts in carcinoma formation	Q34174349
		Different intermediate-sized filaments distinguished by immunofluorescence microscopy	Q34187556
		Diversity, topographic differentiation, and positional memory in human fibroblasts	Q34190312
		Synthesis and secretion of platelet-derived growth factor by human breast cancer cell lines	Q34339034
		Induction of angiogenesis during the transition from hyperplasia to neoplasia	Q34413571
		Tenascin is a stromal marker for epithelial malignancy in the mammary gland	Q34636488
		TGF-beta antagonists: why suppress a tumor suppressor?	Q34691800
		Loss of TGF-beta type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-alpha-, MSP- and HGF-mediated signaling networks	Q34781947
		Growth inhibition and apoptosis in liver myofibroblasts promoted by hepatocyte growth factor leads to resolution from liver cirrhosis.	Q35083777
		The myofibroblast in wound healing and fibrocontractive diseases	Q35170446
		The fibroblast: sentinel cell and local immune modulator in tumor tissue	Q35593451
		The tumor microenvironment: a critical determinant of neoplastic evolution	Q35619420
		The role of epithelial-to-mesenchymal transition in renal fibrosis	Q35643525
		Epithelial to mesenchymal transition in human breast cancer can provide a nonmalignant stroma	Q35748940
		Platelet-derived growth factor (PDGF) in oncogenesis: development of a vascular connective tissue stroma in xenotransplanted human melanoma producing PDGF-BB	Q36051073
		A stromal address code defined by fibroblasts	Q36061032
		Distribution of vascular permeability factor (vascular endothelial growth factor) in tumors: concentration in tumor blood vessels	Q36230478
		Matrix metalloproteinase stromelysin-1 triggers a cascade of molecular alterations that leads to stable epithelial-to-mesenchymal conversion and a premalignant phenotype in mammary epithelial cells	Q36255048
		Identification and characterization of a fibroblast marker: FSP1	Q36382596
		Overexpression of TGF-beta by infiltrated granulocytes correlates with the expression of collagen mRNA in pancreatic cancer	Q36695742
		The human homolog of the JE gene encodes a monocyte secretory protein	Q36794510
		Reconstruction of functionally normal and malignant human breast tissues in mice	Q37415657
		Collagen biosynthesis in nonfibroblastic cell lines	Q37428169
		Fibroblast cell interactions with human melanoma cells affect tumor cell growth as a function of tumor progression	Q37546757
		Leaky vessels, fibrin deposition, and fibrosis: a sequence of events common to solid tumors and to many other types of disease	Q38208141
		Specificity of desmin to avian and mammalian muscle cells	Q39496494
		Genetic predisposition to cancer in man: in vitro studies.	Q40249069
		Fibroblast activation protein increases apoptosis, cell adhesion, and migration by the LX-2 human stellate cell line	Q40370679
		The antifibrotic effects of relaxin in human renal fibroblasts are mediated in part by inhibition of the Smad2 pathway	Q40410173
		Suppression of tumor development and metastasis formation in mice lacking the S100A4(mts1) gene	Q40427707
		PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells.	Q40459317
		Measurement of macromolecular diffusion coefficients in human tumors	Q40560526
		Hepatocyte growth factor gene therapy and angiotensin II blockade synergistically attenuate renal interstitial fibrosis in mice	Q40633055
		Proangiogenic role of tumor-activated hepatic stellate cells in experimental melanoma metastasis	Q40668665
		Cellular changes involved in conversion of normal to malignant breast: importance of the stromal reaction	Q40964604
		In vivo and in vitro invasiveness of a rat colon-cancer cell line maintaining E-cadherin expression: an enhancing role of tumor-associated myofibroblasts	Q41487536
		Regulation of vimentin expression in cultured human mammary epithelial cells	Q41874497
		Monocyte chemotactic protein gene expression by cytokine-treated human fibroblasts and endothelial cells	Q42033561
		Basic fibroblast growth factor expression is increased in human renal fibrogenesis and may mediate autocrine fibroblast proliferation	Q42486417
		Wounding and its role in RSV-mediated tumor formation	Q43752819
		Relaxin enhances in-vitro invasiveness of breast cancer cell lines by up-regulation of matrix metalloproteases	Q44117726
		Ultrastructural localization of the vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) receptor-2 (FLK-1, KDR) in normal mouse kidney and in the hyperpermeable vessels induced by VPF/VEGF-expressing tumors and adenoviral vect	Q44153756
		Mediation of wound-related Rous sarcoma virus tumorigenesis by TGF-beta	Q44225473
		BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury	Q44479221
		Relaxin increases ubiquitin-dependent degradation of fibronectin in vitro and ameliorates renal fibrosis in vivo	Q44487248
		Hyaluronan (hyaluronic acid) and hyaluronectin in the extracellular matrix of human breast carcinomas: comparison between invasive and non-invasive areas	Q44798703
		Intravenous administration of hepatocyte growth factor gene ameliorates diabetic nephropathy in mice	Q45091472
		Electroporation-mediated HGF gene transfection protected the kidney against graft injury	Q45882045
		Human breast carcinoma desmoplasia is PDGF initiated.	Q46033815
		De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent	Q46068963
		Tenascin: an extracellular matrix protein involved in tissue interactions during fetal development and oncogenesis	Q46128262
		Relaxin modulates cardiac fibroblast proliferation, differentiation, and collagen production and reverses cardiac fibrosis in vivo	Q47449181
		Cre recombinase-mediated gene targeting of mesenchymal cells	Q47867267
		Hepatocyte growth factor prevents tissue fibrosis, remodeling, and dysfunction in cardiomyopathic hamster hearts.	Q51817888
P433	issue	5
P407	language of work or name	English	Q1860
P304	page(s)	392-401
P577	publication date	2006-05-01
P1433	published in	Nature Reviews Cancer	Q641657
P1476	title	Fibroblasts in cancer
P478	volume	6

Fibroblasts in cancer

scientific article (publication date: May 2006)

Reverse relations