Ledipasvir and sofosbuvir for 8 or 12 weeks for chronic HCV without cirrhosis

scientific article (publication date: 15 May 2014)

Ledipasvir and sofosbuvir for 8 or 12 weeks for chronic HCV without cirrhosis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1056/NEJMOA1402355
P3181OpenCitations bibliographic resource ID140586
P698PubMed publication ID24720702

P50authorK. Rajender ReddyQ69932454
P2093author name stringChojkier M
McHutchison JG
Muir AJ
Pang PS
Subramanian GM
Symonds WT
Ryan M
Kowdley KV
Hyland RH
Di Bisceglie AM
Ghalib R
Pockros PJ
Schiff E
Shiffman ML
Fried MW
Gordon SC
Bernstein DE
An D
Herring R
Lawitz E
Pound D
Rossaro L
Rustgi V
Svarovskaia E
P433issue20
P407language of work or nameEnglishQ1860
P921main subjectledipasvirQ15409409
sofosbuvirQ2502747
P304page(s)1879-88
P577publication date2014-05-15
P1433published inThe New England Journal of MedicineQ582728
P1476titleLedipasvir and sofosbuvir for 8 or 12 weeks for chronic HCV without cirrhosis
P478volume370

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Q45323933Impact of Hepatitis C Virus Polymorphisms on Direct-Acting Antiviral Treatment Efficacy: Regulatory Analyses and Perspectives
Q35968616Impact of Mutations at Amino Acid 70 in Hepatitis C Virus (HCV) Genotype 1b Core Region on Hepatocarcinogenesis following Eradication of HCV RNA.
Q35501259Impact of all oral anti-hepatitis C virus therapy: A meta-analysis
Q40414089Impact of eradicating hepatitis C virus on the work productivity of chronic hepatitis C (CH-C) patients: an economic model from five European countries
Q36354119Impact of hepatitis C status on 20-year mortality of patients with substance use disorders
Q35985401Impact of hepatitis C virus eradication on hepatocellular carcinogenesis
Q47605707Impact of ledipasvir/sofosbuvir on the work productivity of genotype 1 chronic hepatitis C patients in Asia
Q26782017Impact of new treatment options for hepatitis C virus infection in liver transplantation
Q42190310Implementation and evaluation of a multicomponent quality improvement intervention to improve efficiency of hepatitis C screening and diagnosis
Q36765588Implementation of baby boomer hepatitis C screening and linking to care in gastroenterology practices: a multi-center pilot study
Q52819324Implementation of the Lancet Standing Commission on Liver Disease in the UK.
Q40171277Implications of HCV RNA level at week 4 of direct antiviral treatments for hepatitis C.
Q40480520Importation of generic hepatitis C therapies: bridging the gap between price and access in high-income countries.
Q40501654In Vitro Study on Anti-Hepatitis C Virus Activity of Spatholobus suberectus Dunn.
Q59360894Incidence of Acute Kidney Injury in Patients Coinfected with HIV and Hepatitis C Virus Receiving Tenofovir Disoproxil Fumarate and Ledipasvir/Sofosbuvir in a Real-World, Urban, Ryan White Clinic
Q41039250Increase in nonhepatic diagnoses among persons with hepatitis C hospitalized for any cause, United States, 2004-2011.
Q39692527Increased eligibility for treatment of chronic hepatitis C infection with shortened duration of therapy: Implications for access to care and elimination strategies in Canada
Q30355190Indian National Association for Study of the Liver (INASL) Guidance for Antiviral Therapy Against HCV Infection: Update 2016.
Q26783056Inhibitors of the Hepatitis C Virus Polymerase; Mode of Action and Resistance
Q92772696Initial uptake, time to treatment, and real-world effectiveness of all-oral direct-acting antivirals for hepatitis C virus infection in the United States: A retrospective cohort analysis
Q26781991Injecting drug use: A vector for the introduction of new hepatitis C virus genotypes
Q38364524Innate and adaptive genetic pathways in HCV infection
Q54250224Interaction Between Hepatocellular Carcinoma and Hepatitis C Eradication With Direct-acting Antiviral Therapy.
Q26781331Interferon-Free Hepatitis C Treatment before and after Liver Transplantation: The Role of HCV Drug Resistance
Q36837502Interferon-Free Treatment of Hepatitis C Virus in HIV/Hepatitis C Virus-Coinfected Subjects Results in Increased Serum Low-Density Lipoprotein Concentration
Q26746563Interferon-Free Treatments for Chronic Hepatitis C Genotype 1 Infection
Q28087400Interferon-free combination therapies for the treatment of hepatitis C: current insights
Q34424151Interferon-free therapies for chronic hepatitis C: toward a hepatitis C virus-free world?
Q38530211Interferon-free, direct-acting antiviral therapy for chronic hepatitis C.
Q40298785Interrelationship of hepatitis C virus genotypes with patient characteristics in Bahrain
Q37035896Is increased hepatitis C virus case-finding combined with current or 8-week to 12-week direct-acting antiviral therapy cost-effective in UK prisons? A prevention benefit analysis
Q38556915Is the 25-year hepatitis C marathon coming to an end to declare victory?
Q40791531JSH Guidelines for the Management of Hepatitis C Virus Infection: A 2016 update for genotype 1 and 2.
Q35558268Labour productivity losses caused by premature death associated with hepatitis C in Spain.
Q42212780Lack of a clinically important pharmacokinetic interaction between sofosbuvir or ledipasvir and hormonal oral contraceptives norgestimate/ethinyl estradiol in HCV-uninfected female subjects
Q40466129Late Relapse Versus Hepatitis C Virus Reinfection in Patients With Sustained Virologic Response After Sofosbuvir-Based Therapies.
Q38236179Latest pharmacotherapy options for treating hepatitis C in HIV-infected patients.
Q93052595Ledipasvir and Sofosbuvir for Acute Hepatitis C Virus Monoinfection Associated with a High Risk of Acute Liver Failure
Q36967076Ledipasvir and Sofosbuvir for HCV in Patients Coinfected with HIV-1.
Q57821930Ledipasvir and Sofosbuvir in the Treatment of Early Hepatitis C Virus Infection in HIV-Infected Men
Q41343312Ledipasvir and sofosbuvir fixed-dose combination with and without ribavirin for 12 weeks in treatment-naive and previously treated Japanese patients with genotype 1 hepatitis C: an open-label, randomised, phase 3 trial
Q35019918Ledipasvir and sofosbuvir: Interferon free therapy for hepatitis C virus genotype 1 infection
Q40375140Ledipasvir plus sofosbuvir as salvage therapy for HCV genotype 1 failures to prior NS5A inhibitors regimens.
Q40634052Ledipasvir plus sofosbuvir for 12 weeks in patients with hepatitis C genotype 4 infection
Q99558446Ledipasvir plus sofosbuvir in pregnant women with hepatitis C virus infection: a phase 1 pharmacokinetic study
Q26769621Ledipasvir with sofosbuvir
Q47572592Ledipasvir-Sofosbuvir for 8 Weeks in Non-Cirrhotic Patients with Previously Untreated Genotype 1 HCV Infection ± HIV-1 Co-Infection
Q38740104Ledipasvir-Sofosbuvir for Treating Chronic Hepatitis C: A NICE Single Technology Appraisal-An Evidence Review Group Perspective.
Q38793356Ledipasvir-Sofosbuvir: A Once-Daily Oral Treatment Option for Chronic Hepatitis C Virus Genotype 1 Infection
Q40357542Ledipasvir-sofosbuvir and sofosbuvir plus ribavirin in patients with chronic hepatitis C and bleeding disorders
Q40248569Ledipasvir-sofosbuvir for 6 weeks to treat acute hepatitis C virus genotype 1 or 4 infection in patients with HIV coinfection: an open-label, single-arm trial
Q41102465Ledipasvir-sofosbuvir for hepatitis C genotype 4 infection
Q34454200Ledipasvir-sofosbuvir: interferon-/ribavirin-free regimen for chronic hepatitis C virus infection
Q41347499Ledipasvir/Sofosbuvir (harvoni): improving options for hepatitis C virus infection
Q59356778Ledipasvir/Sofosbuvir Effectively Treats Hepatitis C Virus Infections in an Underserved Population
Q36052231Ledipasvir/Sofosbuvir.
Q47547989Ledipasvir/Sofosbuvir: A Review in Chronic Hepatitis C.
Q34470061Ledipasvir/Sofosbuvir: a review of its use in chronic hepatitis C.
Q40027212Ledipasvir/sofosbuvir fixed-dose combination tablet in Taiwanese patients with chronic genotype 1 hepatitis C virus.
Q45325427Ledipasvir/sofosbuvir for treatment of hepatitis C virus in sofosbuvir-experienced, NS5A treatment-naïve patients: Findings from two randomized trials
Q52594744Ledipasvir/sofosbuvir for treatment-naive and treatment-experienced Chinese patients with genotype 1 HCV: an open-label, phase 3b study.
Q41366537Ledipasvir/sofosbuvir regimens for chronic hepatitis C infection: Insights from a work productivity economic model from the United States
Q53692110Ledipasvir/sofosbuvir with or without ribavirin for 8 or 12 weeks for the treatment of HCV genotype 4 infection: results from a randomised phase III study in Egypt.
Q38992214Ledipasvir/sofosbuvir with or without ribavirin for the treatment of chronic hepatitis C genotype 1: A pairwise meta-analysis.
Q41935150Ledipasvir + Sofosbuvir for Liver Transplant Recipients With Recurrent Hepatitis C: A Systematic Review and Meta-analysis
Q36166222Lethal Mutagenesis of Hepatitis C Virus Induced by Favipiravir.
Q58799836Liver Fibrosis Is Associated With Corrected QT Prolongation During Ledipasvir/Sofosbuvir Treatment for Patients With Chronic Hepatitis C
Q26740320Management of HCV-Associated Liver Cirrhosis
Q26781741Management of Hepatitis C Post-liver Transplantation: a Comprehensive Review
Q31108752Management of Neurologic Manifestations in Patients with Liver Disease.
Q63684293Management of acute HCV infection in the era of direct-acting antiviral therapy
Q38395275Management of post transplant hepatitis C in the direct antiviral agents era.
Q56000943Mathematical Analysis of Viral Replication Dynamics and Antiviral Treatment Strategies: From Basic Models to Age-Based Multi-Scale Modeling
Q42290798Membranous nephropathy associated with hepatitis C virus infection treated with corticosteroids and Ledipasvir-Sofosbuvir: a case report and review of literature
Q38517530Meta-analysis of the efficacy and safety of sofosbuvir for the treatment of hepatitis C virus infection
Q26773183MicroRNAs Expressed during Viral Infection: Biomarker Potential and Therapeutic Considerations
Q40136277Modeling HCV cure after an ultra-short duration of therapy with direct acting agents
Q26864673Modelling hepatitis C therapy--predicting effects of treatment
Q36889376Modelling the interaction between danoprevir and mericitabine in the treatment of chronic HCV infection.
Q36497834Moderate Sustained Virologic Response Rates With 6-Week Combination Directly Acting Anti-Hepatitis C Virus Therapy in Patients With Advanced Liver Disease.
Q26782009Modulation of host lipid metabolism by hepatitis C virus: Role of new therapies
Q40358244Multicenter Comparison Study of both Analytical and Clinical Performance across Four Roche Hepatitis C Virus RNA Assays Utilizing Different Platforms.
Q39031350NS5A inhibitors for the treatment of hepatitis C infection
Q39134413NS5A resistance-associated variants undermine the effectiveness of ledipasvir and sofosbuvir for cirrhotic patients infected with HCV genotype 1b.
Q33672648Naturally occurring drug resistance associated variants to hepatitis C virus direct-acting antiviral agents in treatment-naive HCV genotype 1b-infected patients in China
Q42175503Naturally occurring, resistance-associated hepatitis C virus NS5A variants are linked to interleukin-28B genotype and are sensitive to interferon-based therapy
Q38875280New Direct-Acting Antiviral Therapies for Treatment of Chronic Hepatitis C Virus Infection
Q33560181New Therapies for Hepatitis C Virus Infection
Q91599092New Treatments for Hepatitis C
Q93140950New all-oral HCV therapies for genotype 1: A final good-bye to interferon
Q38664453New direct-acting antivirals in hepatitis C therapy: a review of sofosbuvir, ledipasvir, daclatasvir, simeprevir, paritaprevir, ombitasvir and dasabuvir
Q26800050New era for management of chronic hepatitis C virus using direct antiviral agents: A review
Q39016874New era in treatment options of chronic hepatitis C: focus on safety of new direct-acting antivirals (DAAs).
Q41622257New kids on the block--step by step to an ideal HCV therapy
Q38233834New therapies for hepatitis C: considerations in patients with renal impairment.
Q26795407New treatment strategies for hepatitis C infection
Q37169457New treatments for hepatitis C virus (HCV): scope for preventing liver disease and HCV transmission in England
Q38703743New-Onset Diabetes Mellitus With Exposure to Ledipasvir and Sofosbuvir
Q45324359Newer direct-acting antivirals for hepatitis C virus infection: Perspectives for India
Q54256586No Difference in Effectiveness of 8 vs 12 Weeks of Ledipasvir and Sofosbuvir for Treatment of Hepatitis C in Black Patients.
Q38743836No one size fits all-Shortening duration of therapy with direct-acting antivirals for hepatitis C genotype 1 infection.
Q36396043No scientific basis to restrict 8 weeks of treatment with ledipasvir/sofosbuvir to patients with hepatitis C virus RNA <6,000,000 IU/mL
Q38611842Nonstructural Protein 5A (NS5A) Resistance Profile in Patients with Chronic Hepatitis C Treated with Ledipasvir-Containing Regimens Without Sofosbuvir
Q38318678Novel interventions to prevent HIV and HCV among persons who inject drugs
Q38262922Ombitasvir (ABT-267), a novel NS5A inhibitor for the treatment of hepatitis C.
Q41359261Ombitasvir plus paritaprevir plus ritonavir with or without ribavirin in treatment-naive and treatment-experienced patients with genotype 4 chronic hepatitis C virus infection (PEARL-I): a randomised, open-label trial
Q40239703Ombitasvir, paritaprevir, and ritonavir plus dasabuvir for 8 weeks in previously untreated patients with hepatitis C virus genotype 1b infection without cirrhosis (GARNET): a single-arm, open-label, phase 3b trial
Q38355057Ombitasvir/paritaprevir/ritonavir and dasabuvir tablets for hepatitis C virus genotype 1 infection
Q41514826On computer-intensive simulation and estimation methods for rare-event analysis in epidemic models.
Q41028724Once daily ledipasvir/sofosbuvir fixed-dose combination with ribavirin in patients with inherited bleeding disorders and hepatitis C genotype 1 infection
Q36333842Once-a-Day Harvoni (Ledipasvir plus Sofosbuvir), a New Oral Combination for the Treament of Patients with Genotype 1 Chronic Hepatitis C Infection
Q26830643Oncogenes and RNA splicing of human tumor viruses
Q46644977Open Label Study of 8 vs. 12 Weeks of Ledipasvir/Sofosbuvir in Genotype 6 Treatment Naïve or Experienced Patients
Q38295826Optimal IFN-free therapy in treatment-naïve patients with HCV genotype 1 infection
Q38295831Optimal interferon-free therapy in treatment-experienced chronic hepatitis C patients
Q92052156Optimizing Implementation of Hepatitis C Birth-Cohort Screening and Treatment Strategies: Model-Based Projections
Q38983274Optimizing patient treatment decisions in an era of rapid technological advances: the case of hepatitis C treatment
Q38249065Optimizing triple therapy and IFN/RBV-free regimens for hepatitis C virus infection
Q30376341Outcomes and Costs of Treating Hepatitis C Patients in the Era of First Generation Protease Inhibitors - Results from the PAN Study.
Q92981412Outcomes of Treatment for Hepatitis C in Primary Care, Compared to Hospital-based Care: A Randomized, Controlled Trial in People Who Inject Drugs
Q39141420Outcomes of treatment with direct-acting antivirals for infection with hepatitis C virus genotypes 1-4 in an ambulatory care setting
Q38470584Outcomes, costs and cost-effectiveness of treating hepatitis C with direct acting antivirals
Q48329834Overcoming the resistance to resistance testing: Collecting the data
Q36663835Patient-reported Outcomes in Asian Patients With Chronic Hepatitis C Treated With Ledipasvir and Sofosbuvir
Q30393824Patient-reported and economic outcomes related to sofosbuvir and ledipasvir treatment for chronic hepatitis C.
Q40374154Patients with Haemoglobinopathies and Chronic Hepatitis C: A Real Difficult to Treat Population in 2016?
Q57152417Patterns in Liver-Related Health Outcomes with Hepatitis C Virus Treatments and Health Equity Implications for Decision Makers: A Cohort Analysis of Medicaid Patients
Q35412591Performance of two HCV RNA assays during protease inhibitor-based triple therapy in patients with advanced liver fibrosis and cirrhosis.
Q55017914Persistent Hepatic Inflammation Plays a Role in Hepatocellular Carcinoma After Sustained Virological Response in Patients with HCV Infection.
Q43047022Perspectives of fixed daily dose of sofosbuvir and ledipasvir for the treatment of chronic hepatitis C.
Q38927205Perspectives on HCV: Current Therapeutic Regimens and Drug-Drug Interactions
Q41925685Pharmacokinetic Interactions between Simeprevir and Ledipasvir in Treatment-naïve Hepatitis C virus Genotype 1-infected Patients without Cirrhosis Treated with a Simeprevir/Sofosbuvir/Ledipasvir Regimen
Q38500364Pharmacokinetic and pharmacodynamic evaluation of telaprevir for the treatment of hepatitis C.
Q38995024Pharmacokinetics and pharmacodynamics of sofosbuvir and ledipasvir for the treatment of hepatitis C.
Q55163317Potential epidemiologic, economic, and budgetary impacts of current rates of hepatitis C treatment in medicare and non-medicare populations.
Q35790397Predictive factors associated with hepatitis C antiviral therapy response
Q36358880Presence of Rheumatoid Factor during Chronic HCV Infection Is Associated with Expansion of Mature Activated Memory B-Cells that Are Hypo-Responsive to B-Cell Receptor Stimulation and Persist during the Early Stage of IFN Free Therapy.
Q35735285Prevalence of hepatitis C virus (HCV) variants resistant to NS5A inhibitors in naïve patients infected with HCV genotype 1 in Tunisia
Q58564271Prevalence of hepatitis C virus NS5A resistance-associated substitutions in chronic infection with genotype 1: A pooled analysis based on deposited sequences in GenBank
Q39020651Prevalence of polymorphisms with significant resistance to NS5A inhibitors in treatment-naive patients with hepatitis C virus genotypes 1a and 3a in Sweden
Q38826624Prevention and management of treatment failure to new oral hepatitis C drugs.
Q36751083Pricey pills for an even pricier problem
Q42850943Prisoners treated for hepatitis C with protease inhibitor, New York, USA, 2012.
Q40300359Profile of Roche's cobas® HCV tests
Q40533002Protease Inhibitor Resistance Remains Even After Mutant Strains Become Undetectable by Deep Sequencing
Q40775611Protease inhibitors to treat hepatitis C in the Swiss HIV Cohort Study: high efficacy but low treatment uptake
Q38264060Provision of clinical pharmacist services for individuals with chronic hepatitis C viral infection: Joint Opinion of the GI/Liver/Nutrition and Infectious Diseases Practice and Research Networks of the American College of Clinical Pharmacy
Q26798477Psychiatric and substance use disorders co-morbidities and hepatitis C: Diagnostic and treatment implications
Q26784261Psychosocial assessment and monitoring in the new era of non-interferon-alpha hepatitis C virus treatments
Q42213830QUEST for a cure for hepatitis C virus: the end is in sight
Q37726632Quality of life of Japanese patients with chronic hepatitis C treated with ledipasvir and sofosbuvir
Q40774593Race and Gender Differences in the Use of Direct Acting Antiviral Agents for Hepatitis C Virus.
Q28545971Rational Design and Adaptive Management of Combination Therapies for Hepatitis C Virus Infection
Q36100521Re-treatment of chronic hepatitis C virus genotype 1 infection after relapse: an open-label pilot study
Q40320642Reactivation of hepatitis B in patients of chronic hepatitis C with hepatitis B virus infection treated with direct acting antivirals.
Q40228687Real-World Experiences with the Combination Treatment of Ledipasvir plus Sofosbuvir for 12 Weeks in HCV Genotype 1-Infected Japanese Patients: Achievement of a Sustained Virological Response in Previous Users of Peginterferon plus Ribavirin with HCV
Q39398874Real-World Single-Center Experience with Sofosbuvir-Based Regimens for the Treatment of Chronic Hepatitis C Genotype 1 Patients
Q93337430Real-life experience of ledipasvir and sofosbuvir single-tablet regimen among chronic hepatitis C patients in Turkey
Q41923679Real-life results of sofosbuvir based therapy in chronic hepatitis C -naïve and -experienced patients in Egypt
Q47412911Real-world Outcomes of Hepatitis C Treatment during the Interferon-free Era at an Urban Safety-net Hospital
Q39326974Real-world challenges for hepatitis C virus medications: a critical overview
Q90079314Real-world effectiveness and safety of sofosbuvir and nonstructural protein 5A inhibitors for chronic hepatitis C genotype 1, 2, 3, 4, or 6: a multicentre cohort study
Q64077800Real-world effectiveness and safety of sofosbuvir/velpatasvir and ledipasvir/sofosbuvir hepatitis C treatment in a single centre in Germany
Q59360131Real-world effectiveness of elbasvir/grazoprevir In HCV-infected patients in the US veterans affairs healthcare system
Q39821108Real-world effectiveness of ledipasvir/sofosbuvir in 4,365 treatment-naive, genotype 1 hepatitis C-infected patients
Q40211449Real-world effectiveness of ombitasvir/paritaprevir/ritonavir±dasabuvir±ribavirin in patients with hepatitis C virus genotype 1 or 4 infection: A meta-analysis
Q37646759Real-world experience with interferon-free, direct acting antiviral therapies in Asian Americans with chronic hepatitis C and advanced liver disease
Q47203653Real-world treatment of hepatitis C with second-generation direct-acting antivirals: initial results from a multicentre Canadian retrospective cohort of diverse patients
Q26750476Recent Advances in Antiviral Therapy for Chronic Hepatitis C
Q36575497Recent advances in management of the HIV/HCV coinfected patient
Q28076883Recommendations for the Clinical Management of Hepatitis C in Iran: A Consensus-Based National Guideline
Q45325791Recommendations for the treatment of hepatitis C virus infection in chronic kidney disease: a position statement by the Spanish association of the liver and the kidney.
Q90322598Regulatory T Cell Function Modulated After Successful Direct-Acting Antiviral Treatment for Chronic Hepatitis C Patients
Q36051986Reply: Subgroup Differences in Response to 8 Weeks of Ledipasvir/Sofosbuvir for Chronic Hepatitis C.
Q39301797Resistance Mechanisms in Hepatitis C Virus: implications for Direct-Acting Antiviral Use.
Q50098527Resistance analysis of genotype 3 HCV indicates subtypes inherently resistant to NS5A inhibitors.
Q59355074Resistance detection and re-treatment options in hepatitis C virus-related chronic liver diseases after DAA-treatment failure
Q39610676Response Tailored Protocol Versus the Fixed 12Weeks Course of Dual Sofosbuvir/Daclatasvir Treatment in Egyptian Patients With Chronic Hepatitis C Genotype-4 Infection: A Randomized, Open-label, Non-inferiority Trial.
Q53624781Restrictions of Hepatitis C Treatment for Substance-Using Medicaid Patients: Cost Versus Ethics.
Q40631323Retreatment efficacy and predictors of ledipasvir plus sofosbuvir to HCV genotype 1 in Japan.
Q47121490Retreatment of patients with treatment failure of direct-acting antivirals: Focus on hepatitis C virus genotype 1b.
Q91757404Retrospective Study Demonstrating High Rates of Sustained Virologic Response After Treatment With Direct-Acting Antivirals Among American Indian/Alaskan Natives
Q38703524Review article: safety and tolerability of direct-acting anti-viral agents in the new era of hepatitis C therapy
Q38355069Revolution in hepatitis C antiviral therapy
Q35746343Ribavirin Contributes to Hepatitis C Virus Suppression by Augmenting pDC Activation and Type 1 IFN Production
Q37563692Ribavirin revisited in the era of direct-acting antiviral therapy for hepatitis C virus infection
Q39574126Ribavirin-Free Regimen With Sofosbuvir and Velpatasvir Is Associated With High Efficacy and Improvement of Patient-Reported Outcomes in Patients With Genotypes 2 and 3 Chronic Hepatitis C: Results From Astral-2 and -3 Clinical Trials.
Q26775002Ribavirin: Past, present and future
Q37130040Roadblocks to Accessing Direct-Acting Antiviral Agents for Treatment of Hepatitis C Virus Infection
Q26740216Role of ledipasvir/sofosbuvir combination for genotype 1 hepatitis C virus infection
Q37216507SASLT guidelines: Update in treatment of Hepatitis C virus infection
Q38516135Safety analysis of sofosbuvir and ledipasvir for treating hepatitis C.
Q47202796Safety and Effectiveness of Ledipasvir and Sofosbuvir, With or Without Ribavirin, in Treatment-Experienced Patients with Genotype 1 Hepatitis C Virus Infection and Cirrhosis
Q26745769Safety and efficacy of daclatasvir in the management of patients with chronic hepatitis C
Q31019494Safety and efficacy of ledipasvir-sofosbuvir in black patients with hepatitis C virus infection: A retrospective analysis of phase 3 data
Q40171094Safety and efficacy of ledipasvir/sofosbuvir for the treatment of genotype 1 hepatitis C in subjects aged 65 years or older
Q45325211Safety and efficacy of ledipasvir/sofosbuvir on hepatitis C eradication in hepatitis C virus/human immunodeficiency virus co-infected patients
Q38742966Safety and efficacy of once daily ledipasvir/sofosbuvir fixed-dose combination in patients with chronic hepatitis C.
Q64083501Safety and efficacy of the combination simeprevir-sofosbuvir in HCV genotype 1- and 4-mono-infected patients from the French ANRS CO22 hepather cohort
Q40950331Safety and tolerability of ledipasvir/sofosbuvir with and without ribavirin in patients with chronic hepatitis C virus genotype 1 infection: Analysis of phase III ION trials
Q38818416Safety of direct antiviral agents in the management of hepatitis C.
Q38903835Safety of interferon-free therapies for chronic hepatitis C: a network meta-analysis.
Q47614576Scenarios to manage the hepatitis C disease burden and associated economic impact of treatment in Turkey
Q47560335Severe Steroid-responsive Skin Disorders Related to Ledipasvir and Sofosbuvir for HCV.
Q39259481Short-duration treatment with elbasvir/grazoprevir and sofosbuvir for hepatitis C: A randomized trial
Q38627508Shortening the duration of therapy for chronic hepatitis C infection
Q42174930Shorter treatments for hepatitis C: another step forward?
Q35491398Should NS5A inhibitors serve as the scaffold for all-oral anti-HCV combination therapies?
Q40821688Simeprevir plus sofosbuvir (12 and 8 weeks) in hepatitis C virus genotype 1-infected patients without cirrhosis: OPTIMIST-1, a phase 3, randomized study
Q39479413Sofosbuvir and Ledipasvir for 8 Weeks for the Treatment of Chronic Hepatitis C Virus (HCV) Infection in HCV-Monoinfected and HIV-HCV-Coinfected Individuals: Results From the German Hepatitis C Cohort (GECCO-01).
Q37058681Sofosbuvir and ledipasvir for HIV/HCV co-infected patients
Q39690321Sofosbuvir and ledipasvir improve patient-reported outcomes in patients co-infected with hepatitis C and human immunodeficiency virus
Q40483611Sofosbuvir and ribavirin for 6 weeks is not effective among people with recent hepatitis C virus infection: The DARE-C II study
Q47404164Sofosbuvir and velpatasvir with or without voxilaprevir in direct-acting antiviral-naïve chronic hepatitis C: patient-reported outcomes from POLARIS 2 and 3.
Q57841241Sofosbuvir based regimens in the treatment of chronic hepatitis C genotype 1 infection in African-American patients: a community-based retrospective cohort study
Q42207118Sofosbuvir for the treatment of hepatitis C virus infection
Q38383410Sofosbuvir for treatment of chronic hepatitis C.
Q36261373Sofosbuvir in Combination with Simeprevir +/- Ribavirin in Genotype 4 Hepatitis C Patients with Advanced Fibrosis or Cirrhosis: A Real-World Experience from Belgium
Q38643594Sofosbuvir plus ledipasvir in combination for the treatment of hepatitis C infection
Q39471334Sofosbuvir plus ledispasvir for recurrent hepatitis C in liver transplant recipients
Q38954096Sofosbuvir plus simeprevir for the treatment of genotype 1 chronic hepatitis C: a review of evidence
Q26770024Sofosbuvir treatment and hepatitis C virus infection
Q55243551Sofosbuvir, a New Nucleotide Analogue, for the Treatment of Chronic Hepatitis C Infection.
Q26781773Sofosbuvir, a Significant Paradigm Change in HCV Treatment
Q38245128Sofosbuvir, a novel nucleotide analogue inhibitor used for the treatment of hepatitis C virus
Q60047941Sofosbuvir, velpatasvir and voxilaprevir: a new triple combination for hepatitis C virus treatment. One pill fits all? Is it the end of the road?
Q49953662Sofosbuvir-Based Direct-Acting Antiviral Therapies for HCV in People Receiving Opioid Substitution Therapy: An Analysis of Phase 3 Studies
Q51754955Sofosbuvir-based regimens for the treatment of chronic hepatitis C in severe renal dysfunction.
Q89919346Sofosbuvir-based regimens in the treatment of patients with chronic hepatitis C virus infection: Real-world efficacy in Thailand
Q36460249Sofosbuvir-based therapy for patients with chronic hepatitis C: Early experience of its efficacy and safety in Korea
Q39824771Sofosbuvir: a new oral once-daily agent for the treatment of hepatitis C virus infection
Q24562950Sofosbuvir: a novel oral agent for chronic hepatitis C
Q38222679Sofosbuvir: a review of its use in patients with chronic hepatitis C.
Q40642497Stability-Indicating Method and LC-MS-MS Characterization of Forced Degradation Products of Sofosbuvir
Q57813384Status of Direct-acting Antiviral Therapy for HCV Infection and Remaining Challenges
Q35072099Subgroup differences in response to 8 weeks of ledipasvir/sofosbuvir for chronic hepatitis C
Q40565281Successful Anti-HCV Therapy of a Former Intravenous Drug User with Sofosbuvir and Daclatasvir in a Peritranspant Setting: A Case Report.
Q36446122Successful Retreatment of Chronic HCV Genotype-1 Infection With Ledipasvir and Sofosbuvir After Initial Short Course Therapy With Direct-Acting Antiviral Regimens.
Q50045992Successful retreatment with sofosbuvir plus ledipasvir for cirrhotic patients with hepatitis C virus genotype 1b, who discontinued the prior treatment with asunaprevir plus daclatasvir: A case series and review of the literature
Q36073283Successful sofosbuvir treatment with ribavirin dose reduction for chronic hepatitis C virus genotype 2 infection in a patient with ulcerative colitis: a case report
Q40747468Successful therapy with Ledipasvir/Sofosbuvir for hepatitis C reactivation in a hematopoietic stem cell transplant recipient
Q47680503Successful treatment of chronic hepatitis C with ground ledipasvir/sofosbuvir in a patient with Crohn's disease and short bowel syndrome.
Q38957601Superiority of Interferon-Free Regimens for Chronic Hepatitis C: The Effect on Health-Related Quality of Life and Work Productivity
Q36792338Sustained Virologic Response at 24 Weeks after the End of Treatment Is a Better Predictor for Treatment Outcome in Real-World HCV-Infected Patients Treated by HCV NS3/4A Protease Inhibitors with Peginterferon plus Ribavirin
Q42164795Sustained virologic response achieved after curative treatment of hepatitis C virus-related hepatocellular carcinoma as an independent prognostic factor
Q26768128Systematic Review and Network Meta-Analysis of Randomized Controlled Trials: Comparative Effectiveness and Safety of Direct-Acting Antiviral Agents for Treatment-Naive Hepatitis C Genotype 1
Q36270505Systematic identification of anti-interferon function on hepatitis C virus genome reveals p7 as an immune evasion protein
Q90399068Thalassemia and hepatocellular carcinoma: links and risks
Q37555313The HCV Treatment Revolution Continues: Resistance Considerations, Pangenotypic Efficacy, and Advances in Challenging Populations
Q64132787The Hepatitis C Virus Care Continuum: Linkage to Hepatitis C Virus Care and Treatment Among Patients at an Urban Health Network, Philadelphia, PA
Q26777716The New Era of Interferon-Free Treatment of Chronic Hepatitis C
Q39254698The association between race/ethnicity and the effectiveness of direct antiviral agents for hepatitis C virus infection
Q26795559The changing landscape of hepatitis C virus therapy: focus on interferon-free treatment
Q39449112The cost impact of outreach testing and treatment for hepatitis C in an urban Drug Treatment Unit
Q41919051The cost-effectiveness of one-time hepatitis C screening strategies among adolescents and young adults in primary care settings
Q39137372The cost-effectiveness of testing for NS5a resistance-associated polymorphisms at baseline in genotype 1a-infected (treatment-naïve and treatment-experienced) subjects treated with all-oral elbasvir/grazoprevir regimens in the United States.
Q64913900The dawn of a new era in the treatment of HCV infection: A view from the USA.
Q40326326The discovery of sofosbuvir: a revolution for therapy of chronic hepatitis C.
Q41075768The dollars and sense of chronic hepatitis C infection management
Q40567336The efficacy and safety of direct acting antiviral treatment and clinical significance of drug-drug interactions in elderly patients with chronic hepatitis C virus infection
Q40215846The frequency of acute kidney injury in patients with chronic hepatitis C virus infection treated with sofosbuvir-based regimens
Q41469280The hepatitis C genotype 1 paradox: cost per treatment is increasing, but cost per cure is decreasing
Q41682696The impact of ledipasvir/sofosbuvir on patient-reported outcomes in cirrhotic patients with chronic hepatitis C: the SIRIUS study
Q55288229The management of chronic hepatitis C: 2018 guideline update from the Canadian Association for the Study of the Liver.
Q36286654The need for treatment scale-up to impact HCV transmission in people who inject drugs in Montréal, Canada: a modelling study
Q28086947The new era of hepatitis C virus therapy
Q38634755The paradox of highly effective sofosbuvir-based combination therapy despite slow viral decline: can we still rely on viral kinetics?
Q40078310The potential of signal peptide peptidase as a therapeutic target for hepatitis C.
Q47560943The presence of multiple NS5A RASs is associated with the outcome of sofosbuvir and ledipasvir therapy in NS5A inhibitor-naïve patients with chronic HCV genotype 1b infection in a real-world cohort
Q40201286The risk of early occurrence and recurrence of hepatocellular carcinoma in hepatitis C-infected patients treated with direct-acting antivirals with and without pegylated interferon: A Belgian experience.
Q35750560The role of a hepatitis C virus vaccine: modelling the benefits alongside direct-acting antiviral treatments
Q88337935The role of external beam radiotherapy in the treatment of hepatocellular cancer
Q47552072The safety and efficacy of elbasvir and grazoprevir in participants with hepatitis C virus genotype 1b infection
Q38634221The safety of daclatasvir for the treatment of hepatitis C.
Q38996459The value of cure associated with treating treatment-naïve chronic hepatitis C genotype 1: Are the new all-oral regimens good value to society?
Q38723427Therapeutic Advances in HCV Genotype 1 Infection: Insights from the Society of Infectious Diseases Pharmacists.
Q43034466Therapy of hepatitis C--back to the future.
Q38405059Transformation of hepatitis C antiviral treatment in a national healthcare system following the introduction of direct antiviral agents.
Q34524584Transitioning to highly effective therapies for the treatment of chronic hepatitis C virus infection: a policy statement and implementation guideline
Q38693657Treatment Discontinuation, Adherence, and Real-World Effectiveness Among Patients Treated with Ledipasvir/Sofosbuvir in the United States
Q39112237Treatment Options in Hepatitis C.
Q28552691Treatment Selection Choices Should Not Be Based on Benefits or Costs Alone: A Head-to-Head Randomized Controlled Trial of Antiviral Drugs for Hepatitis C
Q59354362Treatment efficacy of ledipasvir/sofosbuvir for 8 weeks in non-cirrhotic chronic hepatitis C genotype 4 patients
Q37441421Treatment of Chronic Hepatitis C Infection with Sofosbuvir-Based Regimens in a Commercially Insured Patient Population
Q36076049Treatment of Chronic Hepatitis C in the Aged - Does It Impact Life Expectancy? A Decision Analysis
Q38850965Treatment of HCV infection in liver transplant recipients with ledipasvir and sofosbuvir without ribavirin
Q90106344Treatment of HCV infection with direct-acting antiviral agents. Real life experiences from the Euro-Asian region
Q55218109Treatment of Hepatitis C Virus (HCV) Genotype 1 Disease.
Q54268463Treatment of Hepatitis C during Pregnancy-Weighing the Risks and Benefits in Contrast to HIV.
Q40893681Treatment of Hepatitis C in HIV-Infected Patients: Moving Towards an Era of All Oral Regimens
Q41087896Treatment of chronic HCV with sofosbuvir and simeprevir in patients with cirrhosis and contraindications to interferon and/or ribavirin
Q26740219Treatment of chronic hepatitis C with direct-acting antivirals: The role of resistance
Q41437131Treatment of hepatitis C
Q52808389Treatment of hepatitis C genotype 1 infection in Germany: effectiveness and safety of antiviral treatment in a real-world setting.
Q38431523Treatment of hepatitis C in difficult-to-treat patients
Q59351529Treatment of hepatitis C in special populations
Q36519126Treatment of hepatitis C virus infection for adults and children: Updated Swedish consensus recommendations.
Q31160142Treatment of hepatitis C virus infection in patients with cirrhosis and predictive value of model for end-stage liver disease: Analysis of data from the Hepa-C registry.
Q41934079Treatment of hepatitis C virus infection with direct-acting antiviral drugs is safe and effective in patients with hemoglobinopathies.
Q40292229Treatment of hepatitis C virus infection: updated Swedish Guidelines 2016.
Q41923073Treatment of hepatitis C with 8 weeks of ledipasvir/sofosbuvir: highly effective in a predominantly black male patient population
Q41624184Treatment of hepatitis C: what is known?
Q30235034Treatment optimization for HIV/HCV co-infected patients
Q40840459Treatment outcomes with telaprevir-based therapy for HIV/hepatitis C coinfected patients are comparable with hepatitis C monoinfected patients
Q42173527Treatment with ledipasvir and sofosbuvir improves patient-reported outcomes: Results from the ION-1, -2, and -3 clinical trials
Q40352380Treatment with sofosbuvir and ledipasvir without ribavirin for 12 weeks is highly effective for recurrent hepatitis C virus genotype 1b infection after living donor liver transplantation: a Japanese multicenter experience
Q36030846Trends in hospital deaths among human immunodeficiency virus-infected patients during the antiretroviral therapy era, 1995 to 2011
Q40604753Twelve-week ribavirin-free direct-acting antivirals for treatment-experienced Chinese with HCV genotype 1b infection including cirrhotic patients
Q64138093Undiagnosed HIV and HCV Infection in a New York City Emergency Department, 2015
Q57157863Universal Screening of Pregnant Women for Hepatitis C: The Time Is Now
Q38880996Update on Current Evidence for Hepatitis C Therapeutic Options in HCV Mono-infected Patients
Q26775809Update on hepatitis C: Direct-acting antivirals
Q39049155Urgency to treat patients with chronic hepatitis C in Asia
Q38975165Use of direct-acting agents for hepatitis C virus-positive kidney transplant candidates and kidney transplant recipients
Q59355746Using Stepwise Pharmacogenomics and Proteomics to Predict Hepatitis C Treatment Response in Difficult to Treat Patient Populations
Q91656685Velpatasvir and sofosbuvir: How will we use a new drug when the old agents work well?
Q64947352Velpatasvir y sofosbuvir: ¿Por qué utilizar un fármaco nuevo si los antiguos funcionan bien?
Q33760740Ventricular Tachycardia as a Complication of Ledipasvir and Sofosbuvir Treatment for HCV Infection
Q92203399Viral Hepatitis C Therapy: Pharmacokinetic and Pharmacodynamic Considerations: A 2019 Update
Q37721750Viral genome imaging of hepatitis C virus to probe heterogeneous viral infection and responses to antiviral therapies
Q92360165Viral hepatitis C treatment shortening - what is the limit?
Q51073649Viral hepatitis: towards the eradication of HCV and a cure for HBV.
Q38415842Virologic response following combined ledipasvir and sofosbuvir administration in patients with HCV genotype 1 and HIV co-infection
Q35592257Virological response after 6 week triple-drug regimens for hepatitis C: a proof-of-concept phase 2A cohort study
Q38569681What does the pharmacological future of treating chronic hepatitis C look like?
Q38685566Why I do not treat patients for mild disease
Q28550101Will Sofosbuvir/Ledipasvir (Harvoni) Be Cost-Effective and Affordable for Chinese Patients Infected with Hepatitis C Virus? An Economic Analysis Using Real-World Data

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