protein | Q8054 |
P705 | Ensembl protein ID | FBpp0079419 |
FBpp0079420 | ||
FBpp0308609 | ||
P637 | RefSeq protein ID | NP_001260291 |
NP_523523 | ||
NP_723460 | ||
P352 | UniProt protein ID | P16554 |
P682 | biological process | Notch signaling pathway | Q904082 |
asymmetric cell division | Q4812070 | ||
cell fate determination | Q5058196 | ||
central nervous system development | Q14330967 | ||
protein localization | Q14599379 | ||
multicellular organism development | Q14645705 | ||
negative regulation of neuroblast proliferation | Q14818026 | ||
heart development | Q14819288 | ||
glial cell migration | Q14819482 | ||
negative regulation of gene expression | Q14819859 | ||
neuroblast proliferation | Q14859921 | ||
cell fate commitment | Q14860192 | ||
positive regulation of endocytosis | Q14862251 | ||
rhythmic behavior | Q14863667 | ||
regulation of asymmetric cell division | Q14864651 | ||
peripheral nervous system development | Q14873924 | ||
embryonic heart tube development | Q14902766 | ||
negative regulation of Notch signaling pathway | Q14903090 | ||
regulation of Notch signaling pathway | Q14907593 | ||
regulation of neurogenesis | Q14916220 | ||
centrosome localization | Q21097553 | ||
regulation of neuroblast proliferation | Q21109315 | ||
negative regulation of receptor recycling | Q21109464 | ||
neuroblast fate determination | Q21111612 | ||
enteroendocrine cell differentiation | Q21118833 | ||
muscle cell fate specification | Q21120851 | ||
regulation of nervous system development | Q21433509 | ||
asymmetric neuroblast division | Q22295918 | ||
sensory organ precursor cell division | Q22295923 | ||
sensory organ precursor cell fate determination | Q22296023 | ||
neuroblast development | Q22296202 | ||
pericardial nephrocyte differentiation | Q22297599 | ||
Malpighian tubule tip cell differentiation | Q22297612 | ||
ventral cord development | Q22298591 | ||
P681 | cell component | nucleus | Q40260 |
cytoplasm | Q79899 | ||
cell cortex | Q5058180 | ||
basal part of cell | Q14860546 | ||
basal cortex | Q21103311 | ||
P702 | encoded by | numb | Q29731192 |
P703 | found in taxon | Drosophila melanogaster | Q130888 |
P527 | has part(s) | PTB/PI domain | Q24742225 |
NUMB domain | Q24775588 | ||
P680 | molecular function | protein binding | Q167149 |
ATP binding | Q14817981 | ||
nucleotide binding | Q14860365 | ||
Notch binding | Q14914607 | ||
P361 | part of | Numb/numb-like | Q24738886 |
PH-like domain superfamily | Q24786013 | ||
PTB/PI domain, protein family | Q83137700 | ||
NUMB domain, protein family | Q83145648 |
Q34283032 | A novel transmembrane protein recruits numb to the plasma membrane during asymmetric cell division. |
Q43123066 | Ancestry-independent fate specification and plasticity in the developmental timing of a typical Drosophila neuronal lineage |
Q35221182 | Aurora-A acts as a tumor suppressor and regulates self-renewal of Drosophila neuroblasts |
Q28286748 | Control of daughter cell fates during asymmetric division: interaction of Numb and Notch |
Q41073451 | Drosophila Aurora-A kinase inhibits neuroblast self-renewal by regulating aPKC/Numb cortical polarity and spindle orientation. |
Q37593628 | Earmuff restricts progenitor cell potential by attenuating the competence to respond to self-renewal factors |
Q47072023 | Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster |
Q38770014 | Intrinsic regulation of enteroendocrine fate by Numb. |
Q47072557 | Localization-dependent and -independent roles of numb contribute to cell-fate specification in Drosophila |
Q34788601 | Mechanisms of spindle positioning: focus on flies and worms |
Q47071706 | Multiple signalling pathways establish cell fate and cell number in Drosophila malpighian tubules |
Q47071424 | Notch and Numb are required for normal migration of peripheral glia in Drosophila |
Q37120525 | Notch maintains Drosophila type II neuroblasts by suppressing expression of the Fez transcription factor Earmuff |
Q43205606 | Numb and alpha-Adaptin regulate Sanpodo endocytosis to specify cell fate in Drosophila external sensory organs |
Q34392095 | Numb antagonizes Notch signaling to specify sibling neuron cell fates |
Q33689806 | Numb independently antagonizes Sanpodo membrane targeting and Notch signaling in Drosophila sensory organ precursor cells |
Q47071916 | Numb inhibits membrane localization of Sanpodo, a four-pass transmembrane protein, to promote asymmetric divisions in Drosophila |
Q33724489 | Numb proteins specify asymmetric cell fates via an endocytosis- and proteasome-independent pathway. |
Q37259869 | Numb regulates the balance between Notch recycling and late-endosome targeting in Drosophila neural progenitor cells |
Q39631431 | Numb-associated kinase interacts with the phosphotyrosine binding domain of Numb and antagonizes the function of Numb in vivo |
Q40219692 | Polarized endosome dynamics by spindle asymmetry during asymmetric cell division |
Q47071776 | Quantitative analysis of protein dynamics during asymmetric cell division |
Q28207629 | RLIP, an effector of the Ral GTPases, is a platform for Cdk1 to phosphorylate epsin during the switch off of endocytosis in mitosis |
Q47072789 | Regulation of centrosome movements by numb and the collapsin response mediator protein during Drosophila sensory progenitor asymmetric division |
Q41769266 | Regulation of membrane localization of Sanpodo by lethal giant larvae and neuralized in asymmetrically dividing cells of Drosophila sensory organs |
Q42177502 | Sanpodo: a context-dependent activator and inhibitor of Notch signaling during asymmetric divisions |
Q41717902 | The tumor suppressors Brat and Numb regulate transit-amplifying neuroblast lineages in Drosophila |
Q36106839 | Two forkhead transcription factors regulate the division of cardiac progenitor cells by a Polo-dependent pathway |
Q24338740 | aPKC-mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb |
Q47071684 | bHLH-O proteins balance the self-renewal and differentiation of Drosophila neural stem cells by regulating Earmuff expression |
Q29731192 | numb | encodes | P688 |
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