| scholarly article | Q13442814 |
| P356 | DOI | 10.1038/NSB0995-807 |
| P8608 | Fatcat ID | release_gmbkzvbrffdjtlczmxjzegim2e |
| P698 | PubMed publication ID | 7552753 |
| P2093 | author name string | Plasterk RH | |
| Boelens R | |||
| Kaptein R | |||
| Lutzke RA | |||
| Hård K | |||
| Eijkelenboom AP | |||
| P2860 | cites work | Mutational analysis of the integrase protein of human immunodeficiency virus type 2 | Q37245763 |
| Identification of the catalytic and DNA-binding region of the human immunodeficiency virus type I integrase protein | Q38320766 | ||
| Characterization of human immunodeficiency virus type 1 integrase expressed in Escherichia coli and analysis of variants with amino-terminal mutations. | Q38322937 | ||
| Localization of DNA binding activity of HIV-1 integrase to the C-terminal half of the protein | Q38330714 | ||
| The retroviral enzymes | Q40394916 | ||
| Recombining the structures of HIV integrase, RuvC and RNase H. | Q40516667 | ||
| Characterization of the minimal DNA-binding domain of the HIV integrase protein | Q40522244 | ||
| Multidimensional heteronuclear nuclear magnetic resonance of proteins | Q40576237 | ||
| The human immunodeficiency virus integrase protein | Q40721717 | ||
| 1H, 13C, and 15N resonance assignments and secondary structure analysis of the HU protein from Bacillus stearothermophilus using two- and three-dimensional double- and triple-resonance heteronuclear magnetic resonance spectroscopy | Q42595999 | ||
| The HIV integrase catalytic core | Q43750077 | ||
| A calculation strategy for the structure determination of symmetric dimers by 1H NMR. | Q52388559 | ||
| A pulsed field gradient isotope-filtered 3D 13C HMQC-NOESY experiment for extracting intermolecular NOE contacts in molecular complexes. | Q54628775 | ||
| Observation of inter-subunit nuclear Overhauser effects in a dimeric protein. Application to the Arc repressor. | Q54651390 | ||
| Methodological advances in protein NMR | Q60680251 | ||
| The use of osmolytes to facilitate protein NMR spectroscopy | Q61994073 | ||
| Distribution of targets for avian retrovirus DNA integration in vivo | Q72718786 | ||
| Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4 | Q24313595 | ||
| Escherichia coli biotin holoenzyme synthetase/bio repressor crystal structure delineates the biotin- and DNA-binding domains | Q24563755 | ||
| PROCHECK: a program to check the stereochemical quality of protein structures | Q26778411 | ||
| MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures | Q26778412 | ||
| Crystal structure of a Src-homology 3 (SH3) domain | Q27641407 | ||
| Solution structure and DNA-binding properties of a thermostable protein from the archaeon Sulfolobus solfataricus | Q27729809 | ||
| Crystal structure of the mammalian Grb2 adaptor | Q27730180 | ||
| Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases | Q27730298 | ||
| A novel class of winged helix-turn-helix protein: the DNA-binding domain of Mu transposase | Q27730402 | ||
| Hin recombinase bound to DNA: the origin of specificity in major and minor groove interactions | Q27731526 | ||
| Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features | Q27860675 | ||
| Protein structure comparison by alignment of distance matrices | Q27860798 | ||
| Modular binding domains in signal transduction proteins | Q29617351 | ||
| Solution structure of the SH3 domain of Src and identification of its ligand-binding site | Q30195180 | ||
| Genetics of retroviral integration | Q35656800 | ||
| Retroviral integrase domains: DNA binding and the recognition of LTR sequences | Q35914265 | ||
| Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding | Q36243985 | ||
| Determination of the structure of the DNA binding domain of gamma delta resolvase in solution | Q36278799 | ||
| Determination of three-dimensional structures of proteins from interproton distance data by dynamical simulated annealing from a random array of atoms. Circumventing problems associated with folding | Q36437269 | ||
| A mutation at one end of Moloney murine leukemia virus DNA blocks cleavage of both ends by the viral integrase in vivo | Q36701170 | ||
| P433 | issue | 9 | |
| P921 | main subject | HIV | Q15787 |
| SH3 domain | Q24771787 | ||
| P304 | page(s) | 807-810 | |
| P577 | publication date | 1995-09-01 | |
| P1433 | published in | Nature structural biology | Q26842658 |
| P1476 | title | The DNA-binding domain of HIV-1 integrase has an SH3-like fold | |
| P478 | volume | 2 |
| Q27653369 | A Novel Co-Crystal Structure Affords the Design of Gain-of-Function Lentiviral Integrase Mutants in the Presence of Modified PSIP1/LEDGF/p75 |
| Q89729176 | A Peptide Derived from Lens Epithelium-Derived Growth Factor Stimulates HIV-1 DNA Integration and Facilitates Intasome Structural Studies |
| Q34249167 | A critical role of the C-terminal segment for allosteric inhibitor-induced aberrant multimerization of HIV-1 integrase |
| Q33887922 | A large nucleoprotein assembly at the ends of the viral DNA mediates retroviral DNA integration |
| Q73442728 | A metal-induced conformational change and activation of HIV-1 integrase |
| Q37780981 | A new functional role of HIV-1 integrase during uncoating of the viral core |
| Q31072487 | A novel short peptide is a specific inhibitor of the human immunodeficiency virus type 1 integrase |
| Q27676654 | A possible role for the asymmetric C-terminal domain dimer of Rous sarcoma virus integrase in viral DNA binding |
| Q30427188 | A structural tree for proteins containing 3beta-corners |
| Q30432006 | A structural tree for proteins containing S-like beta-sheets |
| Q45423719 | A three-dimensional model of the human immunodeficiency virus type 1 integration complex |
| Q30915736 | An inhibitory monoclonal antibody binds at the turn of the helix-turn-helix motif in the N-terminal domain of HIV-1 integrase |
| Q33756550 | An interlocked dimeric parallel-stranded DNA quadruplex: a potent inhibitor of HIV-1 integrase |
| Q33396954 | An unusual helix turn helix motif in the catalytic core of HIV-1 integrase binds viral DNA and LEDGF. |
| Q30500118 | Architecture of a full-length retroviral integrase monomer and dimer, revealed by small angle X-ray scattering and chemical cross-linking |
| Q38296937 | Assembly and catalysis of concerted two-end integration events by Moloney murine leukemia virus integrase |
| Q37518408 | Biochemical and random mutagenesis analysis of the region carrying the catalytic E152 amino acid of HIV-1 integrase |
| Q30157084 | Biochemical and virological analysis of the 18-residue C-terminal tail of HIV-1 integrase. |
| Q42277905 | Cellular cofactors of lentiviral integrase: from target validation to drug discovery |
| Q43855787 | Characterization of the self association of Avian sarcoma virus integrase by analytical ultracentrifugation |
| Q34190096 | Comparison of multiple molecular dynamics trajectories calculated for the drug-resistant HIV-1 integrase T66I/M154I catalytic domain. |
| Q42119068 | Computational screening of inhibitors for HIV-1 integrase using a receptor based pharmacophore model |
| Q24814060 | Contribution of the C-terminal tri-lysine regions of human immunodeficiency virus type 1 integrase for efficient reverse transcription and viral DNA nuclear import |
| Q37512925 | Critical Contribution of Tyr15 in the HIV-1 Integrase (IN) in Facilitating IN Assembly and Nonenzymatic Function through the IN Precursor Form with Reverse Transcriptase |
| Q33887759 | Critical contacts between HIV-1 integrase and viral DNA identified by structure-based analysis and photo-crosslinking |
| Q30167857 | Crk family adaptors-signalling complex formation and biological roles |
| Q42106132 | Crosslinking and mass spectrometry suggest that the isolated NTD domain dimer of Moloney murine leukemia virus integrase adopts a parallel arrangement in solution |
| Q33900890 | Cryo-EM structures and atomic model of the HIV-1 strand transfer complex intasome |
| Q27625292 | Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: A model for viral DNA binding |
| Q27639109 | Crystal structure of the anti-His tag antibody 3D5 single-chain fragment complexed to its antigen |
| Q27654971 | Crystal structure of the -Me type II restriction endonuclease Hpy99I with target DNA |
| Q30009031 | Crystal structures of the BsPif1 helicase reveal that a major movement of the 2B SH3 domain is required for DNA unwinding |
| Q27651386 | DNA binding to RecD: role of the 1B domain in SF1B helicase activity |
| Q38399251 | Design of inhibitors of the HIV-1 integrase core domain using virtual screening. |
| Q34075007 | Developing G-quartet oligonucleotides as novel anti-HIV agents: focus on anti-HIV drug design |
| Q42019479 | Development and evaluation of a structural model for SF1B helicase Dda. |
| Q30175843 | Dissecting the role of the N-terminal domain of human immunodeficiency virus integrase by trans-complementation analysis |
| Q34461632 | Disulfide-linked integrase oligomers involving C280 residues are formed in vitro and in vivo but are not essential for human immunodeficiency virus replication |
| Q30932059 | Dramatic acceleration of protein folding by stabilization of a nonnative backbone conformation |
| Q36968390 | Dynamic modulation of HIV-1 integrase structure and function by cellular lens epithelium-derived growth factor (LEDGF) protein |
| Q39580790 | Effects of mutations in residues near the active site of human immunodeficiency virus type 1 integrase on specific enzyme-substrate interactions |
| Q40214545 | Evaluation of the functional involvement of human immunodeficiency virus type 1 integrase in nuclear import of viral cDNA during acute infection |
| Q35468454 | FRET analysis reveals distinct conformations of IN tetramers in the presence of viral DNA or LEDGF/p75. |
| Q37333915 | Functional analysis of N-terminal residues of ty1 integrase |
| Q27653000 | Functional and structural characterization of the integrase from the prototype foamy virus |
| Q24797484 | Functional evolution of two subtly different (similar) folds |
| Q39551623 | Functional interactions of the HHCC domain of moloney murine leukemia virus integrase revealed by nonoverlapping complementation and zinc-dependent dimerization |
| Q42091632 | Genetic analyses of conserved residues in the carboxyl-terminal domain of human immunodeficiency virus type 1 integrase |
| Q36065855 | HIV DNA integration |
| Q30175416 | HIV integrase structure and function. |
| Q34247770 | HIV integrase, a brief overview from chemistry to therapeutics |
| Q41479059 | HIV integrase: a target for AIDS therapeutics |
| Q30407372 | HIV virions as nanoscopic test tubes for probing oligomerization of the integrase enzyme. |
| Q37945176 | HIV-1 Integrase-DNA Recognition Mechanisms |
| Q37957767 | HIV-1 integrase inhibitors: a review of their chemical development. |
| Q34050694 | HIV-1 integrase inhibitors: past, present, and future |
| Q38380688 | HIV-1 integrase multimerization as a therapeutic target |
| Q64230148 | Human H4 tail stimulates HIV-1 integration through binding to the carboxy-terminal domain of integrase |
| Q28343322 | Human immunodeficiency virus type 1 integrase: arrangement of protein domains in active cDNA complexes |
| Q33202469 | Identification of an inhibitor-binding site to HIV-1 integrase with affinity acetylation and mass spectrometry |
| Q39591194 | Identification of critical amino acid residues in human immunodeficiency virus type 1 IN required for efficient proviral DNA formation at steps prior to integration in dividing and nondividing cells. |
| Q34785977 | In search of authentic inhibitors of HIV-1 integration |
| Q99635824 | Influence of the amino-terminal sequence on the structure and function of HIV integrase |
| Q37081043 | Integrase, LEDGF/p75 and HIV replication |
| Q24295223 | Interaction of the HIV-1 intasome with transportin 3 protein (TNPO3 or TRN-SR2) |
| Q38304436 | Mapping DNA-binding sites of HIV-1 integrase by protein footprinting |
| Q31035885 | Mapping the epitope of an inhibitory monoclonal antibody to the C-terminal DNA-binding domain of HIV-1 integrase. |
| Q40477773 | Mass spectrometric analysis of the HIV-1 integrase-pyridoxal 5'-phosphate complex reveals a new binding site for a nucleotide inhibitor. |
| Q33385047 | Mass spectrometry-based footprinting of protein-protein interactions |
| Q38312462 | Mechanism of inhibition of HIV-1 integrase by G-tetrad-forming oligonucleotides in Vitro |
| Q64910935 | Model of full-length HIV-1 integrase complexed with viral DNA as template for anti-HIV drug design. |
| Q35260416 | Modeling the HIV-1 Intasome: A Prototype View of the Target of Integrase Inhibitors |
| Q34180538 | Molecular dynamics studies of the wild-type and double mutant HIV-1 integrase complexed with the 5CITEP inhibitor: mechanism for inhibition and drug resistance |
| Q34170581 | Molecular dynamics studies on the HIV-1 integrase catalytic domain |
| Q34063962 | Molecular genetics and target site specificity of retroviral integration |
| Q36098878 | Molecular mechanisms by which human immunodeficiency virus type 1 integrase stimulates the early steps of reverse transcription |
| Q40868886 | Molecular mechanisms in retrovirus DNA integration |
| Q33651120 | Monoclonal antibodies against the minimal DNA-binding domain in the carboxyl-terminal region of human immunodeficiency virus type 1 integrase |
| Q27678141 | Multimode, Cooperative Mechanism of Action of Allosteric HIV-1 Integrase Inhibitors |
| Q39578393 | Mutational scan of the human immunodeficiency virus type 2 integrase protein |
| Q79300526 | Mutations in the C‐terminal domain of ALSV (Avian Leukemia and Sarcoma Viruses) integrase alter the concerted DNA integration process in vitro |
| Q43837693 | N-Terminal domain of HTLV-I integrase. Complexation and conformational studies of the zinc finger |
| Q34226132 | Non-Enzymatic Functions of Retroviral Integrase: The Next Target for Novel Anti-HIV Drug Development |
| Q33601292 | Nuclear trafficking of the HIV-1 pre-integration complex depends on the ADAM10 intracellular domain |
| Q37353786 | Piecing together the structure of retroviral integrase, an important target in AIDS therapy |
| Q24672416 | Posttranslational acetylation of the human immunodeficiency virus type 1 integrase carboxyl-terminal domain is dispensable for viral replication |
| Q40699705 | Potential disruption of protein-protein interactions by graphene oxide |
| Q37144775 | Principles of macromolecular X-ray crystallography |
| Q37950254 | Protein intrinsic disorder as a flexible armor and a weapon of HIV-1. |
| Q34313220 | Protein-protein interactions probed by nuclear magnetic resonance spectroscopy |
| Q35789343 | Raltegravir in HIV-1 infection: Safety and Efficacy in Treatment-naïve Patients |
| Q36452171 | Raltegravir: molecular basis of its mechanism of action |
| Q27628711 | Refined solution structure of the dimeric N-terminal HHCC domain of HIV-2 integrase |
| Q28596842 | Retroviral DNA Integration |
| Q36314249 | Retroviral DNA integration--mechanism and consequences |
| Q33787076 | Retroviral DNA integration. |
| Q34668065 | Retroviral Integrase Structure and DNA Recombination Mechanism |
| Q28073156 | Retroviral Integrase: Then and Now |
| Q24629737 | Retroviral intasome assembly and inhibition of DNA strand transfer |
| Q39273807 | Retroviral intasomes arising |
| Q39176798 | Retroviral integrase protein and intasome nucleoprotein complex structures |
| Q41029973 | Retroviral integrase, putting the pieces together |
| Q34387887 | Retroviral integrases and their cousins |
| Q35873097 | Reversion of a human immunodeficiency virus type 1 integrase mutant at a second site restores enzyme function and virus infectivity |
| Q33889660 | Sequence specificity of viral end DNA binding by HIV-1 integrase reveals critical regions for protein-DNA interaction |
| Q39582953 | Sequential deletion of the integrase (Gag-Pol) carboxyl terminus reveals distinct phenotypic classes of defective HIV-1. |
| Q73469975 | Similarities in the HIV-1 and ASV integrase active sites upon metal cofactor binding |
| Q33885382 | Solution conformation and dynamics of the HIV-1 integrase core domain |
| Q36280733 | Solution structure of the His12 --> Cys mutant of the N-terminal zinc binding domain of HIV-1 integrase complexed to cadmium |
| Q27740763 | Solution structure of the N-terminal zinc binding domain of HIV-1 integrase |
| Q39581624 | Specific and independent recognition of U3 and U5 att sites by human immunodeficiency virus type 1 integrase in vivo. |
| Q28369425 | Stability-activity relationships of a family of G-tetrad forming oligonucleotides as potent HIV inhibitors. A basis for anti-HIV drug design |
| Q38356920 | Strategy to discriminate between high and low affinity bindings of human immunodeficiency virus, type 1 integrase to viral DNA. |
| Q92825482 | Structural Insights on Retroviral DNA Integration: Learning from Foamy Viruses |
| Q30009173 | Structural and sequencing analysis of local target DNA recognition by MLV integrase |
| Q27316560 | Structural basis for functional tetramerization of lentiviral integrase |
| Q34161123 | Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75. |
| Q36806748 | Structural biology of retroviral DNA integration |
| Q30175939 | Structural determinants of metal-induced conformational changes in HIV-1 integrase |
| Q30009248 | Structural dynamics of native and V260E mutant C-terminal domain of HIV-1 integrase |
| Q27636829 | Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein |
| Q27620348 | Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug design |
| Q27749615 | Structure of the catalytic domain of avian sarcoma virus integrase with a bound HIV-1 integrase-targeted inhibitor |
| Q34141071 | Structure-based HIV-1 integrase inhibitor design: a future perspective |
| Q39580599 | Structure-based mutational analysis of the C-terminal DNA-binding domain of human immunodeficiency virus type 1 integrase: critical residues for protein oligomerization and DNA binding |
| Q40954112 | Structures of protein complexes by multidimensional heteronuclear magnetic resonance spectroscopy |
| Q35876147 | Subcellular localization of avian sarcoma virus and human immunodeficiency virus type 1 integrases |
| Q33589910 | Subunit-specific protein footprinting reveals significant structural rearrangements and a role for N-terminal Lys-14 of HIV-1 Integrase during viral DNA binding |
| Q35050390 | Targeting HIV-1 integrase |
| Q28213947 | The C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motif |
| Q37945179 | The Interaction Between Lentiviral Integrase and LEDGF: Structural and Functional Insights |
| Q27734254 | The catalytic domain of human immunodeficiency virus integrase: ordered active site in the F185H mutant |
| Q39195267 | The conformational feasibility for the formation of reaching dimer in ASV and HIV integrase: a molecular dynamics study. |
| Q36281117 | The molecular biology of HIV integrase |
| Q73878403 | The solution structure of the amino-terminal HHCC domain of HIV-2 integrase: a three-helix bundle stabilized by zinc |
| Q39875259 | Ty3 integrase mutants defective in reverse transcription or 3'-end processing of extrachromosomal Ty3 DNA. |
| Q35360391 | Uneven genetic robustness of HIV-1 integrase |
| Q62065988 | X-filtering for a range of coupling constants: application to the detection of intermolecular NOEs |
| Q35922636 | Zinc folds the N-terminal domain of HIV-1 integrase, promotes multimerization, and enhances catalytic activity |
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