scholarly article | Q13442814 |
review article | Q7318358 |
P50 | author | María E Chánez-Cárdenas | Q93365702 |
P2093 | author name string | Jorge Muñoz-Sánchez | |
P2860 | cites work | Heme oxygenase and heme degradation | Q21710702 |
Human heme oxygenase-2: characterization and expression of a full-length cDNA and evidence suggesting that the two HO-2 transcripts may differ by choice of polyadenylation signal | Q24297658 | ||
Hemoxygenase-2 is an oxygen sensor for a calcium-sensitive potassium channel | Q24311958 | ||
The structure, organization and differential expression of the gene encoding rat heme oxygenase-2. | Q48084870 | ||
The 3' flanking region of the human erythropoietin-encoding gene contains nitrogen-regulatory/oxygen-sensing consensus sequences and tissue-specific transcriptional regulatory elements | Q48087037 | ||
Haem can bind to and inhibit mammalian calcium-dependent Slo1 BK channels | Q48181699 | ||
Expression and regulation of heme oxygenase isozymes in the developing mouse cortex | Q48423484 | ||
HO-2 provides endogenous protection against oxidative stress and apoptosis caused by TNF-alpha in cerebral vascular endothelial cells | Q48478299 | ||
Cerebral heme oxygenase 1 and 2 spatial distribution is modulated following injury from hypoxia-ischemia and middle cerebral artery occlusion in rats | Q48485119 | ||
Regulation of heme oxygenase-2 by glucocorticoids in neonatal rat brain: characterization of a functional glucocorticoid response element | Q48762472 | ||
Developmental expression of heme oxygenase isozymes in rat brain. Two HO-2 mRNAs are detected | Q48970739 | ||
Crystal structure of dimeric heme oxygenase-2 from Synechocystis sp. PCC 6803 in complex with heme. | Q50772239 | ||
Co-release of ATP and ACh mediates hypoxic signalling at rat carotid body chemoreceptors. | Q52078714 | ||
Developmentally regulated expression of two transcripts for heme oxygenase-2 with a first exon unique to rat testis: control by corticosterone of the oxygenase protein expression. | Q52172263 | ||
Corticosterone promotes increased heme oxygenase-2 protein and transcript expression in the newborn rat brain. | Q52201476 | ||
Heme oxygenase-1 induction protects murine cortical astrocytes from hemoglobin toxicity. | Q54059269 | ||
Carbon monoxide induces vasodilation and nitric oxide release but suppresses endothelial NOS. | Q54068483 | ||
Biophysical properties and metabolic regulation of a TASK-like potassium channel in rat carotid body type 1 cells | Q44592628 | ||
Heme oxygenase-1 and its reaction product, carbon monoxide, prevent inflammation-related apoptotic liver damage in mice | Q44598581 | ||
Heme Oxygenase-2 Protects against Lipid Peroxidation-Mediated Cell Loss and Impaired Motor Recovery after Traumatic Brain Injury | Q44747461 | ||
Modulation of the NO/CO-cGMP signaling cascade during chronic morphine exposure in mice | Q44964148 | ||
Characterization of rat heme oxygenase-3 gene. Implication of processed pseudogenes derived from heme oxygenase-2 gene | Q44972470 | ||
Heme inhibits human neutrophil apoptosis: involvement of phosphoinositide 3-kinase, MAPK, and NF-kappaB. | Q44987487 | ||
Interaction between endothelial heme oxygenase-2 and endothelin-1 in altered aortic reactivity after hypoxia in rats | Q45107973 | ||
Two heme binding sites are involved in the regulated degradation of the bacterial iron response regulator (Irr) protein. | Q45197492 | ||
Heme oxygenase expression in cultured human trophoblast cells during in vitro differentiation: effects of hypoxia | Q45262897 | ||
Heme oxygenase (HO-1): His-132 stabilizes a distal water ligand and assists catalysis | Q46078167 | ||
Mitochondrial respiratory chain and NAD(P)H oxidase are targets for the antiproliferative effect of carbon monoxide in human airway smooth muscle | Q46465760 | ||
Protective effect of p53 in vascular smooth muscle cells against nitric oxide-induced apoptosis is mediated by up-regulation of heme oxygenase-2. | Q46721643 | ||
The identification and expression of heme oxygenase-2 alternative transcripts in the mouse | Q48012205 | ||
Biliverdin reductase: a major physiologic cytoprotectant | Q24541497 | ||
Comparison of apo- and heme-bound crystal structures of a truncated human heme oxygenase-2 | Q24621015 | ||
Comparison of the heme-free and -bound crystal structures of human heme oxygenase-1 | Q27640232 | ||
Carbon monoxide neurotransmission activated by CK2 phosphorylation of heme oxygenase-2 | Q28207338 | ||
Chromosomal localization of the human heme oxygenase genes: heme oxygenase-1 (HMOX1) maps to chromosome 22q12 and heme oxygenase-2 (HMOX2) maps to chromosome 16p13.3 | Q28245139 | ||
Bilirubin benefits: cellular protection by a biliverdin reductase antioxidant cycle | Q28264545 | ||
Hemeoxygenase-2 as an O2 sensor in K+ channel-dependent chemotransduction | Q28270173 | ||
Physiology and pathophysiology of heme: implications for kidney disease | Q28283790 | ||
Role of Bach-1 in regulation of heme oxygenase-1 in human liver cells: insights from studies with small interfering RNAS | Q28286136 | ||
Heme oxygenase 2 is neuroprotective against intracerebral hemorrhage | Q28295659 | ||
Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications | Q28306266 | ||
Heme oxygenase-1 protein localizes to the nucleus and activates transcription factors important in oxidative stress | Q28510887 | ||
Heme oxygenase-2 is activated by calcium-calmodulin | Q28577171 | ||
Mechanism of heme degradation by heme oxygenase | Q29397702 | ||
Oxygen toxicity, oxygen radicals, transition metals and disease | Q29615096 | ||
Heme oxygenase 2: endothelial and neuronal localization and role in endothelium-dependent relaxation | Q33580047 | ||
Heme degradation and vascular injury. | Q33649898 | ||
NO and CO as second messengers in oxygen sensing in the carotid body | Q33672137 | ||
Enhanced translation of heme oxygenase-2 preserves human endothelial cell viability during hypoxia | Q33744522 | ||
Identification of a thiol/disulfide redox switch in the human BK channel that controls its affinity for heme and CO | Q33924387 | ||
Regulation and role of heme oxygenase in oxidative injury | Q33937118 | ||
Gene regulation of heme oxygenase-1 as a therapeutic target | Q34047237 | ||
Heme oxygenase-1: role in brain aging and neurodegeneration | Q34071515 | ||
Molecular regulation of 5-aminolevulinate synthase. Diseases related to heme biosynthesis | Q34144249 | ||
The heme synthesis and degradation pathways: role in oxidant sensitivity. Heme oxygenase has both pro- and antioxidant properties | Q34203933 | ||
Heme oxygenase isoforms differ in their subcellular trafficking during hypoxia and are differentially modulated by cytochrome P450 reductase. | Q34251131 | ||
The coordinated increased expression of biliverdin reductase and heme oxygenase-2 promotes cardiomyocyte survival: a reductase-based peptide counters β-adrenergic receptor ligand-mediated cardiac dysfunction | Q34421837 | ||
Carbon monoxide-dependent signaling | Q34487832 | ||
Heme oxygenase-1: a novel drug target for atherosclerotic diseases? | Q34581346 | ||
Thiol/Disulfide Redox Switches in the Regulation of Heme Binding to Proteins | Q34589250 | ||
Nox4 NADPH oxidase-derived reactive oxygen species, via endogenous carbon monoxide, promote survival of brain endothelial cells during TNF-α-induced apoptosis | Q34597540 | ||
Heme oxygenase‐1 in growth control and its clinical application to vascular disease | Q35110952 | ||
Cobalt Induction of Hepatic Heme Oxygenase; with Evidence That Cytochrome P -450 Is Not Essential for This Enzyme Activity | Q35114818 | ||
Glutamate-induced calcium signals stimulate CO production in piglet astrocytes | Q35159897 | ||
Selectivity of imidazole-dioxolane compounds for in vitro inhibition of microsomal haem oxygenase isoforms | Q35545244 | ||
Denervation of Carotid Baro‐ and Chemoreceptors in Humans | Q35550958 | ||
Heme oxygenase-2 is a critical determinant for execution of an acute inflammatory and reparative response | Q35607392 | ||
Heme oxygenase-1 in inflammation and cardiovascular disease | Q35660128 | ||
Hypoxia-inducible factor 1alpha stabilization by carbon monoxide results in cytoprotective preconditioning | Q35677054 | ||
Carbon monoxide in biology and medicine | Q35677645 | ||
Free heme toxicity and its detoxification systems in human | Q36139710 | ||
Regulation of ROS production and vascular function by carbon monoxide | Q36183868 | ||
30 some years of heme oxygenase: from a "molecular wrecking ball" to a "mesmerizing" trigger of cellular events | Q36267349 | ||
Role of cysteine residues in heme binding to human heme oxygenase-2 elucidated by two-dimensional NMR spectroscopy | Q36318748 | ||
The heme oxygenase system: update 2005. | Q36342697 | ||
CO as a cellular signaling molecule | Q36364694 | ||
Nucleotide sequence and organization of the rat heme oxygenase gene | Q36426761 | ||
Heme oxygenase-2 is neuroprotective in cerebral ischemia. | Q36438528 | ||
Structural insights into human heme oxygenase-1 inhibition by potent and selective azole-based compounds | Q36591335 | ||
How many transcription factors does it take to turn on the heme oxygenase-1 gene? | Q36600797 | ||
Multiple transcripts encoding heme oxygenase-2 in rat testis: developmental and cell-specific regulation of transcripts and protein | Q36791164 | ||
Isolation and characterization of a cDNA from the rat brain that encodes hemoprotein heme oxygenase-3. | Q36878111 | ||
Hypoxia and heme oxygenases: oxygen sensing and regulation of expression | Q36948663 | ||
Revisiting heme mechanisms. A perspective on the mechanisms of nitric oxide synthase (NOS), Heme oxygenase (HO), and cytochrome P450s (CYP450s). | Q37072871 | ||
Heme oxygenase is necessary for the excitatory response of cultured neonatal rat rostral ventrolateral medulla neurons to hypoxia | Q37086406 | ||
Cerebroprotective functions of HO-2. | Q37090266 | ||
Bilirubin, formed by activation of heme oxygenase-2, protects neurons against oxidative stress injury | Q37187635 | ||
Molecular mechanisms of BK channel activation | Q37223668 | ||
Heme regulatory motifs in heme oxygenase-2 form a thiol/disulfide redox switch that responds to the cellular redox state. | Q37343966 | ||
Heme oxygenase-2 deletion causes endothelial cell activation marked by oxidative stress, inflammation, and angiogenesis | Q37444467 | ||
Rapid induction of heme oxygenase 1 mRNA and protein by hyperthermia in rat brain: heme oxygenase 2 is not a heat shock protein | Q37533031 | ||
The heme oxygenase/biliverdin reductase pathway in drug research and development. | Q37585361 | ||
Complement activation and disease: protective effects of hyperbilirubinaemia | Q37609484 | ||
Evidence that the heme regulatory motifs in heme oxygenase-2 serve as a thiol/disulfide redox switch regulating heme binding | Q37642980 | ||
Differential expression of heme oxygenase-1 in cultured cortical neurons and astrocytes determined by the aid of a new heme oxygenase antibody. Response to oxidative stress | Q54174433 | ||
Coordinated expression of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 and heme oxygenase 2: evidence for a regulatory link between glycolysis and heme catabolism. | Q54490894 | ||
Heme oxygenase-2 is a hemoprotein and binds heme through heme regulatory motifs that are not involved in heme catalysis. | Q54566037 | ||
Domains of rat heme oxygenase-2: the amino terminus and histidine 151 are required for heme oxidation. | Q54657863 | ||
Characterization of two constitutive forms of rat liver microsomal heme oxygenase. Only one molecular species of the enzyme is inducible. | Q55060466 | ||
Partial purification and reconstitution of the heme oxygenase system from pig spleen microsomes. | Q55061447 | ||
Bilirubin inhibits the activation of superoxide-producing NADPH oxidase in a neutrophil cell-free system | Q67913939 | ||
The release of acetylcholine from carotid body tissues. Further study on the effects of acetylcholine and cholinergic blocking agents on the chemosensory discharge | Q68577339 | ||
Purification and characterization of the major constitutive form of testicular heme oxygenase. The noninducible isoform | Q68890134 | ||
Effects of low oxygen on the release of dopamine from the rabbit carotid body in vitro | Q70627465 | ||
Unconjugated bilirubin inhibits in vitro major histocompatibility complex-unrestricted cytotoxicity of human lymphocytes | Q71087476 | ||
Increased release of tumor necrosis factor-alpha and interleukin-6 in women with the syndrome of hemolysis, elevated liver enzymes, and low platelet count | Q71754126 | ||
Differential effects of heme oxygenase isoforms on heme mediation of endothelial intracellular adhesion molecule 1 expression | Q73002791 | ||
Cellular non-heme iron content is a determinant of nitric oxide-mediated apoptosis, necrosis, and caspase inhibition | Q73643152 | ||
Functional analysis of heme regulatory elements of the transcriptional activator Hap1 | Q73938491 | ||
Carbon monoxide controls the proliferation of hypoxic vascular smooth muscle cells | Q73959885 | ||
Heme oxygenase-2 acts to prevent neuronal death in brain cultures and following transient cerebral ischemia | Q74272605 | ||
Imidazole-dioxolane compounds as isozyme-selective heme oxygenase inhibitors | Q79842136 | ||
Catalytically inactive heme oxygenase-2 mutant is cytoprotective | Q80931238 | ||
Dynamic changes in expression of heme oxygenases in mouse heart and liver during hypoxia | Q81152071 | ||
Selective activation of heme oxygenase-2 by menadione | Q82269815 | ||
Hypoxemia induces expression of heme oxygenase-1 and heme oxygenase-2 proteins in the mouse myocardium | Q84698607 | ||
Mechanisms of cell protection by heme oxygenase-1. | Q37670227 | ||
Targeting heme oxygenase-1 for neuroprotection and neuroinflammation in neurodegenerative diseases | Q37779566 | ||
Heme oxygenase-1/carbon monoxide: novel therapeutic strategies in critical care medicine | Q37779568 | ||
The protective role of heme oxygenase-1 in cerebral ischemia | Q37792155 | ||
A central role of heme oxygenase-1 in cardiovascular protection | Q37810954 | ||
Adaptive responses to tissue injury: role of heme oxygenase-1. | Q38123150 | ||
Interaction of heme oxygenase-2 with nitric oxide donors. Is the oxygenase an intracellular 'sink' for NO? | Q38320415 | ||
Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications | Q39648092 | ||
Structural environment dictates the biological significance of heme-responsive motifs and the role of Hsp90 in the activation of the heme activator protein Hap1 | Q39793408 | ||
JunB and JunD regulate human heme oxygenase-1 gene expression in renal epithelial cells | Q40186498 | ||
Hypoxia reduces the expression of heme oxygenase-2 in various types of human cell lines. A possible strategy for the maintenance of intracellular heme level | Q40264976 | ||
Nitric oxide increases carbon monoxide production by piglet cerebral microvessels | Q40645314 | ||
Hypoxia inhibits human recombinant large conductance, Ca(2+)-activated K(+) (maxi-K) channels by a mechanism which is membrane delimited and Ca(2+) sensitive. | Q40734768 | ||
Normal and Heat-Induced Patterns of Expression of Heme Oxygenase-1 (HSP32) in Rat Brain: Hyperthermia Causes Rapid Induction of mRNA and Protein | Q40736064 | ||
Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway | Q40890343 | ||
The heme oxygenase system: a regulator of second messenger gases | Q41455806 | ||
Crystal structure of human heme oxygenase-1. | Q41687640 | ||
Heterogeneity of haem oxygenase 1 and 2 isoenzymes. Rat and primate transcripts for isoenzyme 2 differ in number and size | Q41940159 | ||
Reciprocal regulation of the Ca2+ and H+ sensitivity in the SLO1 BK channel conferred by the RCK1 domain | Q42198642 | ||
Synthesis and release of catecholamines by the cat carotid body in vitro: effects of hypoxic stimulation | Q42207470 | ||
Selection of metalloporphyrin heme oxygenase inhibitors based on potency and photoreactivity | Q42289321 | ||
Characterization of the synthesis and release of catecholamine in the rat carotid body in vitro | Q42484787 | ||
Impact of silencing HO-2 on EC-SOD and the mitochondrial signaling pathway | Q42504746 | ||
Interaction between heme oxygenase-1 and -2 proteins | Q43622921 | ||
O(2) modulates large-conductance Ca(2+)-dependent K(+) channels of rat chemoreceptor cells by a membrane-restricted and CO-sensitive mechanism. | Q43726349 | ||
Heme oxygenase-2 interaction with metalloporphyrins: function of heme regulatory motifs | Q43735655 | ||
Regulation of CO production in cerebral microvessels of newborn pigs | Q44353636 | ||
Stereoselectivity of each of the three steps of the heme oxygenase reaction: hemin to meso-hydroxyhemin, meso-hydroxyhemin to verdoheme, and verdoheme to biliverdin | Q44479675 | ||
P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
P6216 | copyright status | copyrighted | Q50423863 |
P921 | main subject | oxygen | Q629 |
inorganic compound | Q190065 | ||
enzyme | Q8047 | ||
P304 | page(s) | 604981 | |
P577 | publication date | 2014-07-17 | |
P1433 | published in | Oxidative medicine and cellular longevity | Q26840015 |
P1476 | title | A review on hemeoxygenase-2: focus on cellular protection and oxygen response | |
P478 | volume | 2014 |
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