Major Variations in HIV-1 Capsid Assembly Morphologies Involve Minor Variations in Molecular Structures of Structurally Ordered Protein Segments

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Major Variations in HIV-1 Capsid Assembly Morphologies Involve Minor Variations in Molecular Structures of Structurally Ordered Protein Segments is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M116.720557
P932PMC publication ID4933226
P698PubMed publication ID27129282

P50authorRobert TyckoQ18156760
P2093author name stringMarvin J Bayro
Jun-Xia Lu
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Protease cleavage leads to formation of mature trimer interface in HIV-1 capsidQ27342743
Structures of the HIV-1 capsid protein dimerization domain at 2.6 A resolutionQ27617655
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Unclosed HIV-1 capsids suggest a curled sheet model of assemblyQ36683302
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Magic angle spinning NMR reveals sequence-dependent structural plasticity, dynamics, and the spacer peptide 1 conformation in HIV-1 capsid protein assembliesQ37592317
Site-specific structural variations accompanying tubular assembly of the HIV-1 capsid proteinQ37634480
Structural organization of authentic, mature HIV-1 virions and coresQ39744816
Functional Surfaces of the Human Immunodeficiency Virus Type 1 Capsid ProteinQ39748566
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Mechanism of polymorphism and curvature of HIV capsid assemblies probed by 3D simulations with a novel coarse grain modelQ40595970
Assembly properties of the human immunodeficiency virus type 1 CA proteinQ40676680
Image reconstructions of helical assemblies of the HIV-1 CA proteinQ41631451
Backbone dynamics of the N-terminal domain of the HIV-1 capsid protein and comparison with the G94D mutant conferring cyclosporin resistance/dependenceQ44733390
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Fast MAS total through-bond correlation spectroscopyQ48685126
Assembly and analysis of conical models for the HIV-1 core.Q52228420
Magic-angle spinning solid-state NMR spectroscopy of the beta1 immunoglobulin binding domain of protein G (GB1): 15N and 13C chemical shift assignments and conformational analysisQ57100148
Determination of multiple ***φ***-torsion angles in proteins by selective and extensive (13)C labeling and two-dimensional solid-state NMRQ57102615
Structure of the amino-terminal core domain of the HIV-1 capsid proteinQ71142552
Flexibility in HIV-1 Assembly Subunits: Solution Structure of the Monomeric C-Terminal Domain of the Capsid ProteinQ27644938
Structure of full-length HIV-1 CA: a model for the mature capsid latticeQ27648728
Crystal Polymorphism of Protein GB1 Examined by Solid-State NMR Spectroscopy and X-ray DiffractionQ27649177
Solution structure of a double mutant of the carboxy-terminal dimerization domain of the HIV-1 capsid proteinQ27649720
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Structural Convergence between Cryo-EM and NMR Reveals Intersubunit Interactions Critical for HIV-1 Capsid FunctionQ27658179
Disulfide bond stabilization of the hexameric capsomer of human immunodeficiency virusQ27663032
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Structure of a Monomeric Mutant of the HIV-1 Capsid ProteinQ27675009
A structural model for the generation of continuous curvature on the surface of a retroviral capsidQ27677050
Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamicsQ27678383
Molecular Structure of β-Amyloid Fibrils in Alzheimer’s Disease Brain TissueQ27679935
Structure and Dynamics of Full-Length HIV-1 Capsid Protein in SolutionQ27680056
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Crystal structure of dimeric HIV-1 capsid proteinQ27733334
Crystal structure of human cyclophilin A bound to the amino-terminal domain of HIV-1 capsidQ27734262
NMRPipe: a multidimensional spectral processing system based on UNIX pipesQ27860859
1H, 13C and 15N random coil NMR chemical shifts of the common amino acids. I. Investigations of nearest-neighbor effectsQ29616506
Assigning large proteins in the solid state: a MAS NMR resonance assignment strategy using selectively and extensively 13C-labelled proteinsQ30157194
STRUCTURAL VIROLOGY. X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability.Q30279235
Solid-state NMR studies of HIV-1 capsid protein assemblies.Q30384705
Assembly and architecture of HIV.Q30455050
Electron cryotomography of immature HIV-1 virions reveals the structure of the CA and SP1 Gag shellsQ30479297
Maturation of the HIV-1 core by a non-diffusional phase transition.Q30613887
Investigation of the structure and dynamics of the capsid-spacer peptide 1-nucleocapsid fragment of the HIV-1 gag polyprotein by solution NMR spectroscopyQ33724969
Structural and dynamical characterization of tubular HIV-1 capsid protein assemblies by solid state nuclear magnetic resonance and electron microscopyQ33839020
Automated prediction of 15N, 13Calpha, 13Cbeta and 13C' chemical shifts in proteins using a density functional databaseQ34112485
Rapid and accurate calculation of protein 1H, 13C and 15N chemical shiftsQ34199813
An amyloid organelle, solid-state NMR evidence for cross-β assembly of gas vesiclesQ34238892
Simulated self-assembly of the HIV-1 capsid: protein shape and native contacts are sufficient for two-dimensional lattice formationQ35070372
Conformation and dynamics of the Gag polyprotein of the human immunodeficiency virus 1 studied by NMR spectroscopy.Q35212464
Motions on the millisecond time scale and multiple conformations of HIV-1 capsid protein: implications for structural polymorphism of CA assembliesQ35886939
Early stages of the HIV-1 capsid protein lattice formationQ36330057
Dynamic allostery governs cyclophilin A-HIV capsid interplayQ36332027
P433issue25
P407language of work or nameEnglishQ1860
P1104number of pages15
P304page(s)13098-13112
P577publication date2016-04-19
P1433published inJournal of Biological ChemistryQ867727
P1476titleMajor Variations in HIV-1 Capsid Assembly Morphologies Involve Minor Variations in Molecular Structures of Structurally Ordered Protein Segments
P478volume291

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cites work (P2860)
Q47279865Energetics Underlying Twist Polymorphisms in Amyloid Fibrils
Q30276000Helical Conformation in the CA-SP1 Junction of the Immature HIV-1 Lattice Determined from Solid-State NMR of Virus-like Particles
Q64104115Novel Intersubunit Interaction Critical for HIV-1 Core Assembly Defines a Potentially Targetable Inhibitor Binding Pocket
Q49722680Segmental isotopic labeling of HIV-1 capsid protein assemblies for solid state NMR.

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