What can clinicians learn from therapeutic studies about the treatment of acute oral methotrexate poisoning?

scientific article

What can clinicians learn from therapeutic studies about the treatment of acute oral methotrexate poisoning? is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1080/15563650.2016.1271126
P698PubMed publication ID28084171

P50authorAndrew H. DawsonQ37379168
Nicholas A. BuckleyQ37386383
Betty ChanQ89754310
P2860cites workAlmost a tragedy: severe methotrexate toxicity in a hemodialysis patient treated for ectopic pregnancyQ33411737
Clinical characteristics and risk factors for low dose methotrexate toxicity: a cohort of 28 patientsQ33417409
Acute methotrexate ingestions in adults: a report of serious clinical effects and treatmentsQ33562915
A tribute to Sidney Farber-- the father of modern chemotherapyQ33997155
Glucarpidase, leucovorin, and thymidine for high-dose methotrexate-induced renal dysfunction: clinical and pharmacologic factors affecting outcome.Q34131794
Resumption of high-dose methotrexate after acute kidney injury and glucarpidase use in pediatric oncology patientsQ34247793
Methotrexate for ectopic pregnancy: when and how.Q34418588
Evaluating performance of a decision support system to improve methotrexate pharmacotherapy in children and young adults with cancerQ34780653
Pharmacokinetics and pharmacodynamics of methotrexate in non-neoplastic diseasesQ35049306
High dose methotrexate chemotherapy: pharmacokinetics, folate and toxicity in osteosarcoma patientsQ35640471
Position Paper on urine alkalinizationQ35745550
Defining the appropriate dosage of folinic acid after high-dose methotrexate for childhood acute lymphatic leukemia that will prevent neurotoxicity without rescuing malignant cells in the central nervous systemQ35763862
Understanding and managing methotrexate nephrotoxicityQ36516151
Four-year experience with methotrexate exposuresQ36548419
The Memorial Sloan Kettering Cancer Center experience with outpatient administration of high dose methotrexate with leucovorin rescue.Q37081539
Dexamethasone and High-Dose Methotrexate Improve Outcome for Children and Young Adults With High-Risk B-Acute Lymphoblastic Leukemia: A Report From Children's Oncology Group Study AALL0232Q37169331
Fatal pancytopenia in a hemodialysis patient after treatment with low-dose methotrexate.Q37510473
Efficacy of glucarpidase (carboxypeptidase g2) in patients with acute kidney injury after high-dose methotrexate therapyQ37708963
Successful use of intrathecal carboxypeptidase G2 for intrathecal methotrexate overdose: a case study and review of the literatureQ38053652
How long can folinic acid rescue be delayed after high-dose methotrexate without toxicity?Q38137967
Glucarpidase for the management of elevated methotrexate levels in patients with impaired renal functionQ38208131
The past versus the present, 1980-2004: reduction of mean initial low-dose, long-term glucocorticoid therapy in rheumatoid arthritis from 10.3 to 3.6 mg/day, concomitant with early methotrexate, with long-term effectiveness and safety of less than 5Q38250274
A decade of Australian methotrexate dosing errorsQ38852300
Methotrexate: clinical pharmacology, current status and therapeutic guidelinesQ39660818
The clinical pharmacology of methotrexate.new applications of an old drugQ39716312
Clinical Pharmacokinetics of Methotrexate1Q39720628
Pharmacokinetics of high-dose methotrexate in infants aged less than 12 months treated for aggressive brain tumors.Q39911676
The clinical pharmacology of methotrexateQ40149030
Increased therapeutic index using moderate dose methotrexate and leucovorin twice weekly vs. weekly high dose methotrexate-leucovorin in patients with advanced squamous carcinoma of the head and neck: a safe new effective regimenQ42261781
Methotrexate and citrovorum factor rescue in the management of childhood lymphosarcoma and reticulum cell sarcoma (non-Hodgkin's lymphomas): parolonged unmaintained remissionsQ44456216
Pancytopenia related to low-dose methotrexate: study of five cases and review of the literatureQ44498528
High dose methotrexate therapy of solid tumors: observations relating to clinical toxicityQ44502873
Bioavailability of oral vs. subcutaneous low-dose methotrexate in patients with Crohn's diseaseQ44505159
Pharmacokinetics of oral methotrexate in patients with rheumatoid arthritisQ45081072
Treatment of accidental intrathecal methotrexate overdose with intrathecal carboxypeptidase G2.Q45115245
Statistical analysis of relation between plasma methotrexate concentration and toxicity in high-dose methotrexate therapy of childhood nonHodgkin lymphomaQ45147872
High dose methotrexate in adult patients with osteosarcoma: clinical and pharmacokinetic results.Q46667668
Retrospective study on elimination delay of methotrexate in high-dose therapy of childhood acute lymphoblastic leukemia in ChinaQ46961911
Lymphomas in rheumatoid arthritis patients treated with methotrexate: a 3-year prospective study in France.Q50695569
Serum creatinine and creatinine clearance for predicting plasma methotrexate concentrations after high-dose methotrexate chemotherapy for the treatment for childhood lymphoblastic malignancies.Q53085288
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectpoisoningQ114953
methotrexateQ422232
P304page(s)88-96
P577publication date2017-02-01
P1433published inClinical ToxicologyQ1101545
P1476titleWhat can clinicians learn from therapeutic studies about the treatment of acute oral methotrexate poisoning?
P478volume55

Reverse relations

cites work (P2860)
Q47102539Accidental Chronic Poisoning with Methotrexate; Report of Two Cases
Q91590678Acute versus chronic methotrexate poisoning; a cross-sectional study
Q38668482Evaluation of toxicity after acute accidental methotrexate ingestions in children under 6 years old: a 16-year multi-center review.
Q48232372Is it really safe to withhold folinic acid when less than 1000 mg/m2 methotrexate is ingested?
Q53329376Response to the letter regarding "Is it really safe to withhold folinic acid when less than 1000 mg/m2 methotrexate is ingested?"

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