NMR structure-based optimization of Staphylococcus aureus sortase A pyridazinone inhibitors

scientific article

NMR structure-based optimization of Staphylococcus aureus sortase A pyridazinone inhibitors is …
instance of (P31):
editorialQ871232
scholarly articleQ13442814

External links are
P356DOI10.1111/CBDD.12962
P932PMC publication ID5540818
P698PubMed publication ID28160417

P50authorJ. Andrew McCammonQ6104601
Jorge Z. TorresQ47474680
Robert T. ClubbQ59660382
P2093author name stringBrendan R Amer
Jeff Wereszczynski
Michael E Jung
Sung Wook Yi
Lloyd S Miller
Carly A Dillen
Silvia Senese
Albert H Chan
Christopher K Sue
Ethan M Weiner
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The structure of the Staphylococcus aureus sortase-substrate complex reveals how the universally conserved LPXTG sorting signal is recognizedQ24651383
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Activation of Inhibitors by Sortase Triggers Irreversible Modification of the Active SiteQ27645213
Fluorine in pharmaceuticals: looking beyond intuitionQ27648640
The Sortase A Enzyme That Attaches Proteins to the Cell Wall of Bacillus anthracis Contains an Unusual Active Site ArchitectureQ27661761
Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichmentsQ44012277
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Increased US emergency department visits for skin and soft tissue infections, and changes in antibiotic choices, during the emergence of community-associated methicillin-resistant Staphylococcus aureusQ45111112
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Linezolid-resistant Staphylococcus aureus isolated from 2006 through 2008 at six hospitals in Japan.Q54421055
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Protein NMR structure determination with automated NOE assignment using the new software CANDID and the torsion angle dynamics algorithm DYANAQ27860611
Scalable molecular dynamics with NAMDQ27860718
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Glide: a new approach for rapid, accurate docking and scoring. 2. Enrichment factors in database screeningQ29617343
Protein NMR structure determination with automated NOE-identification in the NOESY spectra using the new software ATNOSQ29617863
AnthraxQ29620675
Structures of sortase B from Staphylococcus aureus and Bacillus anthracis reveal catalytic amino acid triad in the active siteQ30163955
Surface proteins of gram-positive bacteria and mechanisms of their targeting to the cell wall envelopeQ33538951
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Crystal structures of Staphylococcus aureus sortase A and its substrate complex.Q34317452
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Staphylococcus aureus sortase mutants defective in the display of surface proteins and in the pathogenesis of animal infectionsQ36980122
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Sortase A Inhibitors: Recent Advances and Future PerspectivesQ38973528
The use of ATP bioluminescence as a measure of cell proliferation and cytotoxicityQ41566049
Emergence of a clinical daptomycin-resistant Staphylococcus aureus isolate during treatment of methicillin-resistant Staphylococcus aureus bacteremia and osteomyelitisQ41847174
Irreversible inhibition of the bacterial cysteine protease-transpeptidase sortase (SrtA) by substrate-derived affinity labels.Q43002164
Therapeutic effect of (Z)-3-(2,5-dimethoxyphenyl)-2-(4-methoxyphenyl) acrylonitrile (DMMA) against Staphylococcus aureus infection in a murine modelQ43078070
P921main subjectStaphylococcus aureusQ188121
P577publication date2017-02-03
P1433published inChemical Biology and Drug DesignQ15749458
P1476titleNMR structure-based optimization of Staphylococcus aureus sortase A pyridazinone inhibitors

Reverse relations

Q89968828Asymmetric Disulfanylbenzamides as Irreversible and Selective Inhibitors of Staphylococcus aureus Sortase Acites workP2860

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