Discovery of Staphylococcus aureus sortase A inhibitors using virtual screening and the relaxed complex scheme

scientific article published on October 2013

Discovery of Staphylococcus aureus sortase A inhibitors using virtual screening and the relaxed complex scheme is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/CBDD.12167
P932PMC publication ID3841297
P698PubMed publication ID23701677
P5875ResearchGate publication ID236906575

P50authorJ. Andrew McCammonQ6104601
P2093author name stringRobert T Clubb
Brendan R Amer
Jeff Wereszczynski
Michael E Jung
Sung Wook Yi
Albert H Chan
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The binding mechanism, multiple binding modes, and allosteric regulation of Staphylococcus aureus Sortase A probed by molecular dynamics simulationsQ43244942
On the role of Staphylococcus aureus sortase and sortase-catalyzed surface protein anchoring in murine septic arthritisQ43981088
Combined pharmacophore and 3D-QSAR study on a series of Staphylococcus aureus Sortase A inhibitorsQ44307807
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Sortase from Staphylococcus aureus does not contain a thiolate-imidazolium ion pair in its active siteQ44489704
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Effect of srtA and srtB gene expression on the virulence of Staphylococcus aureus in animal models of infectionQ44755219
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Curcuma longa L. constituents inhibit sortase A and Staphylococcus aureus cell adhesion to fibronectinQ44828416
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Localization and mutagenesis of the sorting signal binding site on sortase A from Staphylococcus aureus.Q44997437
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Synthesis of (2R,3S) 3-amino-4-mercapto-2-butanol, a threonine analogue for covalent inhibition of sortases.Q46014466
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On the Role of the Crystal Environment in Determining Protein Side-chain ConformationsQ58043852
Flavonols inhibit sortases and sortase-mediated Staphylococcus aureus clumping to fibrinogenQ80036651
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P433issue4
P407language of work or nameEnglishQ1860
P921main subjectStaphylococcus aureusQ188121
virtual screeningQ4112105
P304page(s)418-428
P577publication date2013-10-01
P1433published inChemical Biology and Drug DesignQ15749458
P1476titleDiscovery of Staphylococcus aureus sortase A inhibitors using virtual screening and the relaxed complex scheme
P478volume82

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cites work (P2860)
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Q41336481Quercitrin, an inhibitor of Sortase A, interferes with the adhesion of Staphylococcal aureus.
Q35023691Targeting virulence not viability in the search for future antibacterials.

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