review article | Q7318358 |
scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1035722727 |
P356 | DOI | 10.1186/1747-5341-6-2 |
P932 | PMC publication ID | 3037871 |
P698 | PubMed publication ID | 21276254 |
P5875 | ResearchGate publication ID | 49793622 |
P50 | author | Karola Stotz | Q58449149 |
Maureen A O'Malley | Q59542023 | ||
P2860 | cites work | Development of the human infant intestinal microbiota | Q21003936 |
Evolution of symbiotic bacteria in the distal human intestine | Q21145890 | ||
Genomic and metabolic adaptations of Methanobrevibacter smithii to the human gut | Q22066345 | ||
Finding the missing heritability of complex diseases | Q22122198 | ||
Genetics of Obesity in Humans | Q22241666 | ||
Bias, Discrimination, and Obesity | Q22251006 | ||
Positional cloning of the mouse obese gene and its human homologue | Q22251285 | ||
Microbial ecology of the gastrointestinal tract | Q22255628 | ||
Systems medicine: the future of medical genomics and healthcare | Q24288895 | ||
The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase | Q24299948 | ||
Obesity alters gut microbial ecology | Q24531503 | ||
Diversity of the human intestinal microbial flora | Q24544241 | ||
A humanized gnotobiotic mouse model of host-archaeal-bacterial mutualism | Q24548304 | ||
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance | Q24617743 | ||
A human gut microbial gene catalogue established by metagenomic sequencing | Q24618931 | ||
Molecular mapping of obesity genes | Q36986675 | ||
The epidemiology of obesity: the size of the problem | Q37099078 | ||
Recent advances and remaining gaps in our knowledge of associations between gut microbiota and human health | Q37122143 | ||
Characterizing a model human gut microbiota composed of members of its two dominant bacterial phyla | Q37138595 | ||
Leptin resistance: a prediposing factor for diet-induced obesity | Q37151048 | ||
The effect of neurohormonal factors, epigenetic factors, and gut microbiota on risk of obesity. | Q37293511 | ||
Complex systems modeling for obesity research | Q37293531 | ||
White adipose tissue as endocrine organ and its role in obesity | Q37321523 | ||
Developmental and epigenetic pathways to obesity: an evolutionary-developmental perspective. | Q37366387 | ||
An expanded view of energy homeostasis: neural integration of metabolic, cognitive, and emotional drives to eat. | Q37395143 | ||
Do symbiotic bacteria subvert host immunity? | Q37445498 | ||
Human genetics illuminates the paths to metabolic disease | Q37634967 | ||
The changed metabolic world with human brown adipose tissue: therapeutic visions. | Q37726545 | ||
Bridging the gap between systems biology and medicine | Q38508961 | ||
Basic and applied research: a meaningful distinction? | Q38510616 | ||
Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice | Q39725584 | ||
Long-term effects of obesity on employment and work limitations among U.S. Adults, 1986 to 1999. | Q40280707 | ||
Common major gene inheritance of extreme overweight. | Q42066817 | ||
A systems-oriented multilevel framework for addressing obesity in the 21st century. | Q42559014 | ||
Lost in translation--basic science in the era of translational research | Q42929679 | ||
Candidate-gene approaches for studying complex genetic traits: practical considerations | Q44636099 | ||
Evidence for a strong genetic influence on childhood adiposity despite the force of the obesogenic environment | Q45221585 | ||
Modulation of Igf2 genomic imprinting in mice induced by 5-azacytidine, an inhibitor of DNA methylation | Q46064175 | ||
Neonatal leptin treatment reverses developmental programming | Q46601500 | ||
Does size really matter? Weight and values in public health | Q47210502 | ||
What are the consequences of the disappearing human microbiota? | Q47429245 | ||
Regulation of energy intake and the body weight: the glucostatic theory and the lipostatic hypothesis | Q47440924 | ||
Leptin therapy in insulin-deficient type I diabetes | Q24620780 | ||
Variations in DNA elucidate molecular networks that cause disease | Q24622333 | ||
Metagenomic analysis of the human distal gut microbiome | Q24633486 | ||
Diet and the epigenetic (re)programming of phenotypic differences in behavior | Q24634401 | ||
The NIH Human Microbiome Project | Q24642619 | ||
From observation to experimentation: leptin action in the mediobasal hypothalamus | Q24644953 | ||
Leptin at 14 y of age: an ongoing story | Q24644972 | ||
Innate immunity and intestinal microbiota in the development of Type 1 diabetes | Q24647312 | ||
A core gut microbiome in obese and lean twins | Q24649648 | ||
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity | Q24650037 | ||
Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies | Q24651076 | ||
Revisiting leptin's role in obesity and weight loss | Q24653878 | ||
Mechanisms underlying the resistance to diet-induced obesity in germ-free mice | Q24676006 | ||
Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"? | Q24685208 | ||
Translational Medicine: A two-way road | Q24802385 | ||
An obesity-associated gut microbiome with increased capacity for energy harvest | Q27860515 | ||
The gut microbiota as an environmental factor that regulates fat storage | Q28131676 | ||
Honor thy symbionts | Q28202174 | ||
The thrifty phenotype hypothesis | Q28216485 | ||
A nonadaptive scenario explaining the genetic predisposition to obesity: the "predation release" hypothesis | Q28235767 | ||
Persistent epigenetic differences associated with prenatal exposure to famine in humans | Q28298905 | ||
Targeted disruption of the melanocortin-4 receptor results in obesity in mice | Q28302831 | ||
Prevalence of overweight and obesity in the United States, 1999-2004 | Q28305811 | ||
A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene | Q28475923 | ||
The leptin receptor | Q28509967 | ||
Worlds within worlds: evolution of the vertebrate gut microbiota | Q28754891 | ||
Brown adipose tissue: function and physiological significance | Q29547448 | ||
Ecological and evolutionary forces shaping microbial diversity in the human intestine | Q29547586 | ||
The human microbiome project | Q29547661 | ||
A microbial symbiosis factor prevents intestinal inflammatory disease | Q29614263 | ||
Genetics of gene expression and its effect on disease | Q29614591 | ||
Molecular analysis of commensal host-microbial relationships in the intestine | Q29614776 | ||
Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5 | Q29615053 | ||
Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice | Q29615055 | ||
Human gut microbiota in obesity and after gastric bypass | Q29615813 | ||
Leptin and the regulation of body weight in mammals | Q29615976 | ||
Central regulation of energy balance: inputs, outputs and leptin resistance | Q36118735 | ||
Prenatal exposure to the Dutch famine and disease in later life: an overview | Q36127666 | ||
The many faces of ghrelin: new perspectives for nutrition research? | Q36196760 | ||
The (dual) origin of epigenetics | Q36238499 | ||
What aspects of body fat are particularly hazardous and how do we measure them? | Q36336942 | ||
Is obesity an inflammatory illness? Role of low-grade inflammation and macrophage infiltration in human white adipose tissue | Q36563483 | ||
Epigenetics, disease, and therapeutic interventions | Q36590880 | ||
Thematic review series: systems biology approaches to metabolic and cardiovascular disorders. Reverse engineering gene networks to identify key drivers of complex disease phenotypes | Q36609005 | ||
Non-genomic transgenerational inheritance of disease risk | Q36709421 | ||
Racialized genetics and the study of complex diseases: the thrifty genotype revisited | Q36806258 | ||
Worldwide trends in childhood overweight and obesity. | Q36954471 | ||
Obesity: Causes and control of excess body fat. | Q47754200 | ||
Molecular characterization of the mouse agouti locus. | Q48143334 | ||
Translational research: moving discovery to practice | Q48333022 | ||
A heliocentric view of leptin | Q48729716 | ||
Fetal origins of hyperphagia, obesity, and hypertension and postnatal amplification by hypercaloric nutrition. | Q51555125 | ||
An invitation to the marriage of metagenomics and metabolomics. | Q51679413 | ||
The politics of pathology: how obesity became an epidemic disease. | Q51927585 | ||
Health as intra-systemic integrity: rethinking the foundations of systems biology and nanomedicine. | Q51950488 | ||
Evidence and ethics in medicine. | Q53133104 | ||
Early differences in fecal microbiota composition in children may predict overweight. | Q53219254 | ||
INFANT MORTALITY, CHILDHOOD NUTRITION, AND ISCHAEMIC HEART DISEASE IN ENGLAND AND WALES | Q56619923 | ||
Obesity: historical development of scientific and cultural ideas | Q57223984 | ||
The Search for Human Obesity Genes | Q57314388 | ||
What makes a good genetic association study? | Q57943305 | ||
Gut microbiota: a potential new territory for drug targeting | Q58045758 | ||
Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): relation to reduced fetal growth | Q58995516 | ||
Whatever happened to leptin? | Q59062529 | ||
What’s in a Name? In Search of Leptin’s Physiologic Role1 | Q59702481 | ||
Genetics of obesity | Q60803735 | ||
No causal link between obesity and probiotics | Q60843168 | ||
Fat (fat) and tubby (tub): two autosomal recessive mutations causing obesity syndromes in the mouse | Q68618542 | ||
Genetics of obesity | Q72918962 | ||
Epigenetic change in IGF2R is associated with fetal overgrowth after sheep embryo culture | Q73435273 | ||
Maternal undernutrition during the preimplantation period of rat development causes blastocyst abnormalities and programming of postnatal hypertension | Q74281065 | ||
Obesity and the environment: where do we go from here? | Q78947050 | ||
Attrition and Translation | Q79203462 | ||
Translational medicine: can it really facilitate the transition of research "from bench to bedside"? | Q81607529 | ||
Novel pharmacotherapies for obesity poised to enter market | Q84817768 | ||
Computational systems biology | Q29616655 | ||
Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome | Q29617424 | ||
Weight-reducing effects of the plasma protein encoded by the obese gene | Q29617934 | ||
Effects of the obese gene product on body weight regulation in ob/ob mice | Q29617935 | ||
Identification and expression cloning of a leptin receptor, OB-R | Q29620255 | ||
Obesity and the regulation of energy balance | Q30080025 | ||
Biohumanities: rethinking the relationship between biosciences, philosophy and history of science, and society. | Q30369432 | ||
The clinical applications of a systems approach | Q33242858 | ||
Predominant role of host genetics in controlling the composition of gut microbiota | Q33363139 | ||
Population adiposity and climate change | Q33431797 | ||
Leveraging leptin for type I diabetes? | Q33739927 | ||
Microbes in gastrointestinal health and disease | Q33943525 | ||
Size at birth and resilience to effects of poor living conditions in adult life: longitudinal study | Q33948592 | ||
How to interpret a genome-wide association study | Q34010528 | ||
The role of depot fat in the hypothalamic control of food intake in the rat. | Q34231666 | ||
Inflammation: the link between insulin resistance, obesity and diabetes | Q34286695 | ||
Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks | Q34301257 | ||
Adipokines: inflammation and the pleiotropic role of white adipose tissue | Q34356530 | ||
Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice | Q34376178 | ||
Microbial biota of the human intestine: a tribute to some pioneering scientists | Q34440266 | ||
Unseen forces: the influence of bacteria on animal development | Q34497947 | ||
The challenges of modeling mammalian biocomplexity | Q34551720 | ||
The nature of systems biology | Q34582744 | ||
Epigenetic programming by maternal behavior and pharmacological intervention. Nature versus nurture: let's call the whole thing off. | Q34584248 | ||
Glucocorticoid programming of pituitary-adrenal function: mechanisms and physiological consequences | Q34612073 | ||
The social environment and the epigenome | Q34728015 | ||
Human colonic microbiota associated with diet, obesity and weight loss | Q34823807 | ||
Appetite and energy balance signals from adipocytes. | Q35140191 | ||
Depression and obesity | Q35189669 | ||
From functional genomics to systems biology: concepts and practices | Q35638937 | ||
Living with the past: evolution, development, and patterns of disease | Q35890929 | ||
Mathematical models in microbial systems biology | Q35903256 | ||
The genetics of human obesity | Q36036700 | ||
The gut and energy balance: visceral allies in the obesity wars | Q36080128 | ||
Epigenetic programming of stress responses through variations in maternal care | Q36092264 | ||
P921 | main subject | obesity | Q12174 |
P304 | page(s) | 2 | |
P577 | publication date | 2011-01-28 | |
P1433 | published in | Philosophy, Ethics, and Humanities in Medicine | Q15766818 |
P1476 | title | Intervention, integration and translation in obesity research: Genetic, developmental and metaorganismal approaches | |
P478 | volume | 6 |
Q34947361 | Beyond bench and bedside: disentangling the concept of translational research |
Q57265185 | Bigger, faster, better? Rhetorics and practices of large-scale research in contemporary bioscience |
Q47620325 | Epigenetics: ambiguities and implications |
Q28741456 | Realizing the promise of population biobanks: a new model for translation |
Search more.