Allosteric Autoinhibition Pathway in Transcription Factor ERG: Dynamics Network and Mutant Experimental Evaluations.

scientific article

Allosteric Autoinhibition Pathway in Transcription Factor ERG: Dynamics Network and Mutant Experimental Evaluations. is …
instance of (P31):
scholarly articleQ13442814

External links are
P8978DBLP publication IDjournals/jcisd/YeQLLC17
P356DOI10.1021/ACS.JCIM.7B00073
P932PMC publication ID5730271
P698PubMed publication ID28425706

P50authorWei YeQ86494041
Ray LuoQ47098696
Haifeng ChenQ75721314
P2093author name stringHao Liu
Tianle Qian
P2860cites workCytoscape: a software environment for integrated models of biomolecular interaction networksQ24515682
Improved side-chain torsion potentials for the Amber ff99SB protein force fieldQ24616749
The Ews-ERG fusion protein can initiate neoplasia from lineage-committed haematopoietic cellsQ24811898
Virus assembly and maturation: auto-regulation through allosteric molecular switchesQ26865510
Structural basis of autoregulation of phenylalanine hydroxylaseQ27618272
Structure and autoregulation of the insulin-like growth factor 1 receptor kinaseQ27635962
Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinasesQ27644421
Structural Mechanisms of Allostery and Autoinhibition in JNK Family KinasesQ27675044
Autoinhibition of ETV6 (TEL) DNA Binding: Appended Helices Sterically Block the ETS DomainQ27679088
Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibitedQ27679276
Steric Mechanism of Auto-Inhibitory Regulation of Specific and Non-Specific DNA Binding by the ETS Transcriptional Repressor ETV6Q27680868
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.Q27824849
Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteinsQ28291920
Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanesQ29397708
Principles of c-di-GMP signalling in bacteriaQ29615333
Eukaryotic transcriptional regulatory proteinsQ29618290
Dynamic coupling between the SH2 and SH3 domains of c-Src and Hck underlies their inactivation by C-terminal tyrosine phosphorylationQ30168286
The structural and dynamic basis of Ets-1 DNA binding autoinhibition.Q30978213
Understanding network concepts in modulesQ33286658
Test and Evaluation of ff99IDPs Force Field for Intrinsically Disordered ProteinsQ33851634
Analysis of a 10-ns molecular dynamics simulation of mouse acetylcholinesteraseQ34176038
The Ets family contains transcriptional activators and repressors involved in angiogenesis.Q34225095
TMPRSS2:ETV4 gene fusions define a third molecular subtype of prostate cancerQ34508696
Protein backbone chemical shifts predicted from searching a database for torsion angle and sequence homologyQ34645831
Energetic dissection of Gleevec's selectivity toward human tyrosine kinases.Q34703677
The affinity of Ets-1 for DNA is modulated by phosphorylation through transient interactions of an unstructured regionQ34806524
Dynamical networks in tRNA:protein complexesQ34974676
The Lrp family of transcriptional regulatorsQ35098855
Ets proteins in biological control and cancerQ35701558
The ets multigene family is conserved throughout the MetazoaQ35858162
Autoinhibited proteins as promising drug targetsQ35880107
Routine Microsecond Molecular Dynamics Simulations with AMBER on GPUs. 1. Generalized BornQ35948015
Structural coupling of the inhibitory regions flanking the ETS domain of murine Ets-1.Q36279666
Autoinhibition and relief mechanism by the proteolytic processing of Toll-like receptor 8.Q36710364
Synergistic Modification Induced Specific Recognition between Histone and TRIM24 via Fluctuation Correlation Network AnalysisQ36800023
Kinetic analysis of biosensor data: elementary tests for self-consistency.Q36843895
The allosteric communication pathways in KIX domain of CBPQ37143502
Improving the Efficiency of Free Energy Calculations in the Amber Molecular Dynamics PackageQ37263004
An allosteric kinase inhibitor binds the p21-activated kinase autoregulatory domain covalently.Q39805071
Routine Microsecond Molecular Dynamics Simulations with AMBER on GPUs. 2. Explicit Solvent Particle Mesh EwaldQ40291611
PI 3-kinase is a dual specificity enzyme: autoregulation by an intrinsic protein-serine kinase activity.Q40790718
Binding induced folding in p53-MDM2 complexQ41816238
New force field on modeling intrinsically disordered proteins.Q44063793
50 years of allosteric interactions: the twists and turns of the modelsQ46140335
Kink turn sRNA folding upon L7Ae binding using molecular dynamics simulationsQ46206776
Detection of errors of interpretation in experiments in enzyme kinetics.Q52061807
Collective motions in proteins: A covariance analysis of atomic fluctuations in molecular dynamics and normal mode simulationsQ52465150
Algorithm 97: Shortest pathQ56170978
Particle mesh Ewald: An N⋅log(N) method for Ewald sums in large systemsQ56750591
Fluctuation and Cross-correlation Analysis of Protein Motions Observed in Nanosecond Molecular Dynamics SimulationsQ57204729
Recognition Mechanism between Lac Repressor and DNA with Correlation Network AnalysisQ57274991
The ETS-domain transcription factor familyQ77199453
P4510describes a project that usesCytoscapeQ3699942
P433issue5
P921main subjectautoinhibitionQ60728737
P304page(s)1153-1165
P577publication date2017-04-25
P1433published inJournal of Chemical Information and ModelingQ3007982
P1476titleAllosteric Autoinhibition Pathway in Transcription Factor ERG: Dynamics Network and Mutant Experimental Evaluations
P478volume57

Reverse relations

cites work (P2860)
Q90394828Allosteric mechanism of an oximino-piperidino-piperidine antagonist for the CCR5 chemokine receptor
Q47579834Allosteric mechanism of quinoline inhibitors for HIV RT-associated RNase with MD simulation and dynamics fluctuation network.
Q91639254Dynamical important residue network (DIRN): network inference via conformational change
Q92618487Integration of network models and evolutionary analysis into high-throughput modeling of protein dynamics and allosteric regulation: theory, tools and applications
Q57903227Order-disorder transition of intrinsically disordered kinase inducible transactivation domain of CREB
Q90307982Singular value decomposition for the correlation of atomic fluctuations with arbitrary angle
Q47591493Structure-based prediction of protein allostery

Search more.