Neutrophil mobilization from the bone marrow during polymicrobial sepsis is dependent on CXCL12 signaling

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Neutrophil mobilization from the bone marrow during polymicrobial sepsis is dependent on CXCL12 signaling is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4049/JIMMUNOL.1100588
P932PMC publication ID3635667
P698PubMed publication ID21690321
P5875ResearchGate publication ID51235658

P50authorLyle L MoldawerQ92147747
Philip EfronQ114427345
P2093author name stringRobert M Strieter
Clayton E Mathews
Reuben Ramphal
Alex G Cuenca
Kindra M Kelly-Scumpia
Philip O Scumpia
Kerri A O'Malley
Robert D Winfield
Matthew J Delano
Elizabeth Warner
Sonia Gabrilovich
Paul G Heyworth
Terri C Thayer
Phillips B Harrington
Drake Laface
P2860cites workEpidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of careQ27860820
The epidemiology of sepsis in the United States from 1979 through 2000Q29547760
The pathophysiology and treatment of sepsisQ29619103
Lymphoid organ development and cell migrationQ31156611
CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrowQ33968069
Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonistQ34412254
Increased natural CD4+CD25+ regulatory T cells and their suppressor activity do not contribute to mortality in murine polymicrobial sepsis.Q34572664
Treatment with GITR agonistic antibody corrects adaptive immune dysfunction in sepsisQ34581804
Cecal ligation and puncture.Q34680364
Adoptive transfer of apoptotic splenocytes worsens survival, whereas adoptive transfer of necrotic splenocytes improves survival in sepsisQ35144095
Regulation of systemic and local neutrophil responses by G-CSF during pulmonary Pseudomonas aeruginosa infectionQ35751086
Inferences, questions and possibilities in Toll-like receptor signallingQ35829752
Inflammation controls B lymphopoiesis by regulating chemokine CXCL12 expressionQ35834713
MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsisQ36229458
Regulation of neutrophil homeostasisQ36667600
Defective innate immunity predisposes murine neonates to poor sepsis outcome but is reversed by TLR agonists.Q36843705
Sepsis induces early alterations in innate immunity that impact mortality to secondary infectionQ37166367
Control of granulocytes and macrophages: molecular, cellular, and clinical aspectsQ37500434
Supplementation of CXCL12 (CXCL12) induces homing of CD11c+ dendritic cells to the spleen and enhances control of Plasmodium berghei malaria in BALB/c miceQ39018241
G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4.Q40724468
G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrowQ41788910
CXCR4 is required for the quiescence of primitive hematopoietic cellsQ42090614
G-CSF is an essential regulator of neutrophil trafficking from the bone marrow to the bloodQ42527033
Stromal cell derived factor 1 synthesis by spleen cells in rodent malaria, and the effects of in vivo supplementation of SDF-1alpha and CXCR4 receptor blockerQ43494866
Protective effects of C5a blockade in sepsisQ44260666
MyD88 mediates neutrophil recruitment initiated by IL-1R but not TLR2 activation in immunity against Staphylococcus aureusQ44537222
Differential effects of macrophage inflammatory chemokine-2 and keratinocyte-derived chemokine on hemorrhage-induced neutrophil priming for lung inflammation: assessment by adoptive cells transfer in miceQ47982077
Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency, and impaired neutrophil mobilizationQ52507472
Increased survival in sepsis by in vivo adenovirus-induced expression of IL-10 in dendritic cellsQ64379002
Antibody immunotherapy of gram-negative bacterial sepsis in an immunosuppressed animal modelQ68127649
Polymorphonuclear leukocyte (PMN) migration in streptococcal pneumonia: comparison of older PMN with those recently released from the marrowQ71623707
The Acute Respiratory Distress SyndromeQ71987757
Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonistQ73652781
CXCR-4 desensitization is associated with tissue localization of hemopoietic progenitor cellsQ73720870
Polymorphonuclear leukocytes released from the bone marrow preferentially sequester in lung microvesselsQ73784090
"Emergency" granulopoiesis in G-CSF-deficient mice in response to Candida albicans infectionQ73876968
Bacteremic pneumococcal pneumonia: bone marrow release and pulmonary sequestration of neutrophilsQ74318670
Toll-like receptors control activation of adaptive immune responsesQ74486847
Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsisQ74539695
Cutting edge: myeloid differentiation factor 88 deficiency improves resistance against sepsis caused by polymicrobial infectionQ74754482
The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironmentQ77402792
Functional CXCR4-expressing microparticles and SDF-1 correlate with circulating acute myelogenous leukemia cellsQ79362792
Platelet-derived stromal cell-derived factor-1 regulates adhesion and promotes differentiation of human CD34+ cells to endothelial progenitor cellsQ80217129
TLRs 2 and 4 are not involved in hypersusceptibility to acute Pseudomonas aeruginosa lung infectionsQ81180253
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectsepsisQ183134
P304page(s)911-918
P577publication date2011-06-20
P1433published inJournal of ImmunologyQ3521441
P1476titleNeutrophil mobilization from the bone marrow during polymicrobial sepsis is dependent on CXCL12 signaling
P478volume187