Redundant functions of Rac GTPases in inner ear morphogenesis

scientific article

Redundant functions of Rac GTPases in inner ear morphogenesis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YDBIO.2011.12.008
P932PMC publication ID3267834
P698PubMed publication ID22182523
P5875ResearchGate publication ID51900853

P2093author name stringXiaowei Lu
Doris K Wu
Conor W Sipe
Cynthia M Grimsley-Myers
P2860cites workCharacterization of RAC3, a novel member of the Rho familyQ24321818
Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulationQ24672832
Rho GTPases: biochemistry and biologyQ27860645
The role of Six1 in mammalian auditory system developmentQ28188638
FGF/FGFR-2(IIIb) signaling is essential for inner ear morphogenesisQ28506828
Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathwayQ28509023
The role of Math1 in inner ear development: Uncoupling the establishment of the sensory primordium from hair cell fate determinationQ28510708
Pax2 contributes to inner ear patterning and optic nerve trajectoryQ28511597
Eya1 regulates the growth of otic epithelium and interacts with Pax2 during the development of all sensory areas in the inner earQ28585081
Sox2 is required for sensory organ development in the mammalian inner earQ28585583
Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordiaQ28587212
Six1 controls patterning of the mouse otic vesicleQ28589213
The Dlx5 homeobox gene is essential for vestibular morphogenesis in the mouse embryo through a BMP4-mediated pathwayQ28589239
Otx1 and Otx2 activities are required for the normal development of the mouse inner earQ28590207
The small GTPase Rac1 regulates auditory hair cell morphogenesisQ28591364
Wnt-dependent regulation of inner ear morphogenesis is balanced by the opposing and supporting roles of Shh.Q28591489
Gbx2 is required for the morphogenesis of the mouse inner ear: a downstream candidate of hindbrain signalingQ28592042
Specification of the mammalian cochlea is dependent on Sonic hedgehogQ28593205
The role of Pax2 in mouse inner ear developmentQ28595027
neurogenin1 is essential for the determination of neuronal precursors for proximal cranial sensory gangliaQ29615041
Collective cell migration in morphogenesis, regeneration and cancerQ29616634
Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumorsQ29619814
Connecting the ear to the brain: Molecular mechanisms of auditory circuit assemblyQ30398554
Dicer regulates the development of nephrogenic and ureteric compartments in the mammalian kidneyQ30429774
Journey to the grave: signaling events regulating removal of apoptotic cellsQ30443921
Expression of the transcription factors GATA3 and Pax2 during development of the mammalian inner ear.Q52125141
Otx1 null mutant mice show partial segregation of sensory epithelia comparable to lamprey ears.Q52127986
Roles of beta-catenin in inner ear development in rat embryos.Q52166298
Development of the mouse inner ear and origin of its sensory organs.Q52188228
Genetic deletion of Rac1 GTPase reveals its critical role in actin stress fiber formation and focal adhesion complex assembly.Q53622986
Development of the inner ear of the mouse: a radioautographic study of terminal mitosesQ72334432
Cell proliferation and cell death in the developing chick inner ear: spatial and temporal patternsQ73414711
Branchio-oto-renal syndromeQ79611476
Wnt signals mediate a fate decision between otic placode and epidermisQ82444199
E-cadherin engagement stimulates proliferation via Rac1Q30444212
BMP/SMAD signaling regulates the cell behaviors that drive the initial dorsal-specific regional morphogenesis of the otocyst.Q30497098
Vang-like protein 2 and Rac1 interact to regulate adherens junctionsQ33629181
Generation of rac3 null mutant mice: role of Rac3 in Bcr/Abl-caused lymphoblastic leukemia.Q33863062
The rho GTPase Rac1 is required for proliferation and survival of progenitors in the developing forebrainQ34090993
Shaping the mammalian auditory sensory organ by the planar cell polarity pathwayQ34154050
Cross-talk between Rac1 GTPase and dysregulated Wnt signaling pathway leads to cellular redistribution of beta-catenin and TCF/LEF-mediated transcriptional activationQ34349607
Mouse Eya homologues of the Drosophila eyes absent gene require Pax6 for expression in lens and nasal placodeQ34414173
Rho GTPases as key transducers of proliferative signals in g1 cell cycle regulationQ35681628
Programmed cell death in the development of the vertebrate inner ear.Q35838752
Force measurements in E-cadherin-mediated cell doublets reveal rapid adhesion strengthened by actin cytoskeleton remodeling through Rac and Cdc42.Q36322829
Tissue organization by cadherin adhesion molecules: dynamic molecular and cellular mechanisms of morphogenetic regulationQ36567245
Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling.Q36666693
Rho GTPases and cell cycle controlQ36693460
Patterning and morphogenesis of the vertebrate inner ear.Q36950119
Rac-dependent cyclin D1 gene expression regulated by cadherin- and integrin-mediated adhesionQ37143866
Rac GTPases play critical roles in early T-cell developmentQ37169134
Myosin II regulates extension, growth and patterning in the mammalian cochlear duct.Q37200935
Anoikis: a necessary death program for anchorage-dependent cellsQ37245449
Eya1 gene dosage critically affects the development of sensory epithelia in the mammalian inner ear.Q37294806
Rac1 GTPase: a "Rac" of all trades.Q37371665
Patterning and cell fate in ear developmentQ37402638
Line up and listen: Planar cell polarity regulation in the mammalian inner ear.Q37512664
Expression and function of FGF10 in mammalian inner ear developmentQ37524712
Dynamics of adherens junctions in epithelial establishment, maintenance, and remodelingQ37855367
Craniofacial, vestibular and bone defects in mice lacking the Distal-less-related gene Dlx5.Q38322087
Fgf3 is required for dorsal patterning and morphogenesis of the inner ear epitheliumQ38440251
Beta-catenin-independent Wnt pathways: signals, core proteins, and effectors.Q38497330
Rac1 deletion in mouse neutrophils has selective effects on neutrophil functions.Q40646102
Rac1 protects epithelial cells against anoikisQ40803889
The role of FGF-3 in early inner ear development: an analysis in normal and kreisler mutant miceQ40946155
Dlx5 regulates regional development of the branchial arches and sensory capsulesQ41683496
Targeting of cre to the Foxg1 (BF-1) locus mediates loxP recombination in the telencephalon and other developing head structuresQ41739151
The small GTPase Rac suppresses apoptosis caused by serum deprivation in fibroblastsQ41924876
Generation of Pax2-Cre mice by modification of a Pax2 bacterial artificial chromosomeQ46063842
Sonic hedgehog promotes mouse inner ear progenitor cell proliferation and hair cell generation in vitroQ46890781
Cellular growth and rearrangement during the development of the mammalian organ of CortiQ47887091
Sequence and expression pattern of the Stra7 (Gbx-2) homeobox-containing gene induced by retinoic acid in P19 embryonal carcinoma cellsQ48068766
Cell proliferation during the early compartmentalization of the Xenopus laevis inner ear.Q50457640
A fate map of chick otic cup closure reveals lineage boundaries in the dorsal otocyst.Q50493881
P4510describes a project that usesImageJQ1659584
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectmorphogenesisQ815547
P304page(s)172-186
P577publication date2011-12-11
P1433published inDevelopmental BiologyQ3025402
P1476titleRedundant functions of Rac GTPases in inner ear morphogenesis
P478volume362

Reverse relations

cites work (P2860)
Q28536871An alteration in ELMOD3, an Arl2 GTPase-activating protein, is associated with hearing impairment in humans
Q26801278Assembly of hair bundles, an amazing problem for cell biology
Q101142716In silico analysis of inner ear development using public whole embryonic body single-cell RNA-sequencing data
Q58586679Loss of ARHGEF6 Causes Hair Cell Stereocilia Deficits and Hearing Loss in Mice
Q64244340Rho-Family Small GTPases: From Highly Polarized Sensory Neurons to Cancer Cells

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