Structure and mechanism of rhomboid protease

scientific article

Structure and mechanism of rhomboid protease is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.R112.422378
P932PMC publication ID3668704
P698PubMed publication ID23585569

P2093author name stringYoshinori Akiyama
Yi Xue
Ya Ha
P2860cites workRhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signalingQ24298141
Exosome-related multi-pass transmembrane protein TSAP6 is a target of rhomboid protease RHBDD1-induced proteolysisQ24336330
Functional and evolutionary implications of enhanced genomic analysis of rhomboid intramembrane proteasesQ24672054
The rhomboids: a nearly ubiquitous family of intramembrane serine proteases that probably evolved by multiple ancient horizontal gene transfersQ24791324
Rhomboid 4 (ROM4) affects the processing of surface adhesins and facilitates host cell invasion by Toxoplasma gondiiQ27315046
Structural basis for intramembrane proteolysis by rhomboid serine proteasesQ27640962
The crystal structure of the rhomboid peptidase from Haemophilus influenzae provides insight into intramembrane proteolysisQ27641079
Open-cap conformation of intramembrane protease GlpGQ27643738
Catalytic mechanism of rhomboid protease GlpG probed by 3,4-dichloroisocoumarin and diisopropyl fluorophosphonateQ35728121
Rhomboid proteins: conserved membrane proteases with divergent biological functionsQ36657554
Rhomboid protease dynamics and lipid interactionsQ37186369
Structure and mechanism of intramembrane proteaseQ37342295
The PARL family of mitochondrial rhomboid proteasesQ37666154
Conservation of intramembrane proteolytic activity and substrate specificity in prokaryotic and eukaryotic rhomboidsQ39615340
Diverse substrate recognition mechanisms for rhomboids; thrombomodulin is cleaved by Mammalian rhomboidsQ39675497
Architectural and thermodynamic principles underlying intramembrane protease functionQ39810882
In vivo analysis reveals substrate-gating mutants of a rhomboid intramembrane protease display increased activity in living cellsQ39861099
Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neuronsQ41791615
Alternative topogenesis of Mgm1 and mitochondrial morphology depend on ATP and a functional import motor.Q41825724
Reaction of serine proteases with substituted isocoumarins: discovery of 3,4-dichloroisocoumarin, a new general mechanism based serine protease inhibitorQ42225238
The intramembrane active site of GlpG, an E. coli rhomboid protease, is accessible to water and hydrolyses an extramembrane peptide bond of substratesQ42619989
m-AAA protease-driven membrane dislocation allows intramembrane cleavage by rhomboid in mitochondriaQ42976619
Insights into the effect of detergents on the full-length rhomboid protease from Pseudomonas aeruginosa and its cytosolic domainQ43275271
Proteolytic action of GlpG, a rhomboid protease in the Escherichia coli cytoplasmic membraneQ45068680
Cleavage of a multispanning membrane protein by an intramembrane serine protease.Q45821721
A group of genes required for pattern formation in the ventral ectoderm of the Drosophila embryo.Q52460673
Sequence features of substrates required for cleavage by GlpG, an Escherichia coli rhomboid protease.Q54441401
Crystal structure of a rhomboid family intramembrane protease.Q54453416
The Role of L1 Loop in the Mechanism of Rhomboid Intramembrane Protease GlpGQ27648936
The structural basis for catalysis and substrate specificity of a rhomboid proteaseQ27664874
Insights into substrate gating in H. influenzae rhomboidQ27666656
Structure of Rhomboid Protease in a Lipid EnvironmentQ27666691
Large Lateral Movement of Transmembrane Helix S5 Is Not Required for Substrate Access to the Active Site of Rhomboid Intramembrane ProteaseQ27677496
Conformational Change in Rhomboid Protease GlpG Induced by Inhibitor Binding to Its S′ SubsitesQ27678610
Activity-based protein profiling of the Escherichia coli GlpG rhomboid protein delineates the catalytic coreQ27682232
Crystal structure of a bacterial signal peptidase in complex with a beta-lactam inhibitorQ27766053
Intramembrane proteolysis of Mgm1 by the mitochondrial rhomboid protease is highly promiscuous regarding the sequence of the cleaved hydrophobic segmentQ27935115
Mitochondrial membrane remodelling regulated by a conserved rhomboid proteaseQ27935531
Two Plasmodium rhomboid proteases preferentially cleave different adhesins implicated in all invasive stages of malariaQ27972762
Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humansQ28145545
Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodelingQ28506506
Intramembrane proteolysis mediates shedding of a key adhesin during erythrocyte invasion by the malaria parasiteQ30043432
Solution structure and dynamics of the N-terminal cytosolic domain of rhomboid intramembrane protease from Pseudomonas aeruginosa: insights into a functional role in intramembrane proteolysisQ31069065
Rhomboid cleaves Star to regulate the levels of secreted SpitzQ33274072
Monocyclic β-lactams are selective, mechanism-based inhibitors of rhomboid intramembrane proteasesQ33777125
Reconstitution of intramembrane proteolysis in vitro reveals that pure rhomboid is sufficient for catalysis and specificityQ33836549
Sequence-specific intramembrane proteolysis: identification of a recognition motif in rhomboid substratesQ34092101
Drosophila rhomboid-1 defines a family of putative intramembrane serine proteasesQ34098885
A conserved mechanism for extracellular signaling in eukaryotes and prokaryotes.Q34155681
Intramembrane cleavage of AMA1 triggers Toxoplasma to switch from an invasive to a replicative mode.Q34157453
Mammalian EGF receptor activation by the rhomboid protease RHBDL2Q34178493
Identifying nonpolar transbilayer helices in amino acid sequences of membrane proteinsQ34181973
Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domainQ34207965
Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACEQ34247194
iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPSQ34247201
Intramembrane proteolysis: theme and variations.Q34342964
Mechanism of intramembrane proteolysis investigated with purified rhomboid proteases.Q34379351
Structural analysis of a rhomboid family intramembrane protease reveals a gating mechanism for substrate entryQ34581109
Rhomboid protease AarA mediates quorum-sensing in Providencia stuartii by activating TatA of the twin-arginine translocaseQ34600228
Enzymatic analysis of a rhomboid intramembrane protease implicates transmembrane helix 5 as the lateral substrate gateQ34623352
Rhomboid proteases and their biological functionsQ34793043
P433issue22
P407language of work or nameEnglishQ1860
P304page(s)15430-15436
P577publication date2013-04-12
P1433published inJournal of Biological ChemistryQ867727
P1476titleStructure and mechanism of rhomboid protease
P478volume288

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cites work (P2860)
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