Endogenous neurosteroid synthesis modulates seizure frequency

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Endogenous neurosteroid synthesis modulates seizure frequency is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/ANA.21989
P932PMC publication ID2918659
P698PubMed publication ID20437568
P5875ResearchGate publication ID44568578

P50authorJaideep KapurQ58934394
P2093author name stringJohn Williamson
Chengsan Sun
Courtney Lawrence
Brandon Scott Martin
P2860cites workAnticonvulsant activity of progesterone and neurosteroids in progesterone receptor knockout mice.Q44776094
Altered expression of the delta subunit of the GABAA receptor in a mouse model of temporal lobe epilepsy.Q45084946
Altered localization of GABA(A) receptor subunits on dentate granule cell dendrites influences tonic and phasic inhibition in a mouse model of epilepsy.Q46150356
Studies on neurosteroids XXV. Influence of a 5alpha-reductase inhibitor, finasteride, on rat brain neurosteroid levels and metabolismQ46403244
Finasteride blocks the reduction in ictal activity produced by exogenous estrous cyclicityQ48447769
Infusion of 3alpha,5alpha-THP to the pontine reticular formation attenuates PTZ-induced seizures.Q51375192
Finasteride, a 5alpha-reductase inhibitor, blocks the anticonvulsant activity of progesterone in mice.Q51479099
Diminished allopregnanolone enhancement of GABA(A) receptor currents in a rat model of chronic temporal lobe epilepsyQ28365693
The dentate gyrus as a control point for seizures in the hippocampus and beyondQ30311316
GABAergic integration of progesterone and androgen feedback to gonadotropin-releasing hormone neuronsQ30434370
Diminished neurosteroid sensitivity of synaptic inhibition and altered location of the alpha4 subunit of GABA(A) receptors in an animal model of epilepsyQ30436043
A combination of ketamine and diazepam synergistically controls refractory status epilepticus induced by cholinergic stimulationQ30436689
Neuroactive steroids reduce neuronal excitability by selectively enhancing tonic inhibition mediated by delta subunit-containing GABAA receptorsQ33717685
Anticonvulsant activity of neurosteroids: correlation with gamma-aminobutyric acid-evoked chloride current potentiationQ34323789
The role of neurosteroids in the pathophysiology and treatment of catamenial epilepsyQ37227965
Anticonvulsant profile of the progesterone metabolite 5 alpha-pregnan-3 alpha-ol-20-oneQ41327094
Neuroactive steroids protect against pilocarpine- and kainic acid-induced limbic seizures and status epilepticus in miceQ42549975
Neurosteroid withdrawal model of perimenstrual catamenial epilepsy.Q43665513
Seizure exacerbation associated with inhibition of progesterone metabolismQ44325286
P433issue5
P921main subjectseizureQ6279182
P304page(s)689-693
P577publication date2010-05-01
P1433published inAnnals of NeurologyQ564414
P1476titleEndogenous neurosteroid synthesis modulates seizure frequency
P478volume67

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cites work (P2860)
Q3501691711β-Hydroxylase inhibitors protect against seizures in mice by increasing endogenous neurosteroid synthesis.
Q35996697A mouse kindling model of perimenstrual catamenial epilepsy
Q49598739A novel therapeutic approach for treatment of catamenial epilepsy
Q48214543Allopregnanolone potentiates the glutamate-mediated seizures induced by 4-aminopyridine in rat hippocampus in vivo
Q47848096Catamenial-like seizure exacerbation in mice with targeted ablation of extrasynaptic δGABA-a receptors in the brain.
Q58701285Dynamic and Sex-Specific Changes in Gonadotropin-Releasing Hormone Neuron Activity and Excitability in a Mouse Model of Temporal Lobe Epilepsy
Q36240741Finasteride inhibits the disease-modifying activity of progesterone in the hippocampus kindling model of epileptogenesis
Q24605690GABAergic transmission in temporal lobe epilepsy: the role of neurosteroids
Q36173874Neuroendocrine aspects of catamenial epilepsy
Q37320505Neurosteroid interactions with synaptic and extrasynaptic GABA(A) receptors: regulation of subunit plasticity, phasic and tonic inhibition, and neuronal network excitability
Q56383791Neurosteroid regulation of GABA receptors: A role in catamenial epilepsy
Q30252495Neurosteroid-sensitive δ-GABAA receptors: A role in epileptogenesis?
Q33792908Neurosteroids and GABAergic signaling in health and disease
Q27026373Neurosteroids and their role in sex-specific epilepsies
Q34401221Neurosteroids on the epilepsy chessboard-keeping seizures in check.
Q92234228Progesterone receptor activation regulates seizure susceptibility
Q30418813Progesterone vs placebo therapy for women with epilepsy: A randomized clinical trial.
Q30430081Receptors with low affinity for neurosteroids and GABA contribute to tonic inhibition of granule cells in epileptic animals
Q35971997Role of anticonvulsant and antiepileptogenic neurosteroids in the pathophysiology and treatment of epilepsy
Q37057683Role of hormones and neurosteroids in epileptogenesis.
Q24614956Role of neurosteroids in the anticonvulsant activity of midazolam
Q36179368Sex and hormonal influences on seizures and epilepsy
Q36705079Temporal lobe epilepsy exacerbation during pharmacological inhibition of endogenous neurosteroid synthesis
Q36656363The brain, seizures and epilepsy throughout life: understanding a moving target

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