PKC-eta mediates glioblastoma cell proliferation through the Akt and mTOR signaling pathways

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PKC-eta mediates glioblastoma cell proliferation through the Akt and mTOR signaling pathways is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1037152712
P356DOI10.1038/SJ.ONC.1208093
P8608Fatcat IDrelease_ts5eciapbzg2fl4uh5ucgynj4e
P698PubMed publication ID15489897
P5875ResearchGate publication ID8226749

P2093author name stringIsa M Hussaini
Patrick M Martin
Jae-Won Soh
Sean E Aeder
P2860cites workPhorbol 12-myristate 13-acetate induces protein kinase ceta-specific proliferative response in astrocytic tumor cellsQ22254077
Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTORQ28144113
TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and functionQ28204144
Regulation of eukaryotic initiation factor eIF2B: glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulinQ28262178
Identification of phosphorylation sites in the translational regulator, PHAS-I, that are controlled by insulin and rapamycin in rat adipocytesQ28307131
FRAP/mTOR is required for proliferation and patterning during embryonic development in the mouseQ28507537
Stat3 as an oncogeneQ29614606
Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanismQ29614737
Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4EQ29618009
The role of protein kinase C in cell surface signal transduction and tumour promotionQ29618532
The molecular heterogeneity of protein kinase C and its implications for cellular regulationQ29619947
Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycinQ29620399
4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathwayQ29620730
Cooperation between two growth factors promotes extended self-renewal and inhibits differentiation of oligodendrocyte-type-2 astrocyte (O-2A) progenitor cellsQ33751730
Cytoplasmic signaling pathways that regulate cardiac hypertrophyQ34142151
MCF-7 breast cancer cells transfected with protein kinase C-alpha exhibit altered expression of other protein kinase C isoforms and display a more aggressive neoplastic phenotypeQ34212221
Signaling pathways regulating gliomagenesisQ35056649
Acquisition of the glioblastoma phenotype during astrocytoma progression is associated with loss of heterozygosity on 10q25-qterQ35787692
Myogenic signaling of phosphatidylinositol 3-kinase requires the serine-threonine kinase Akt/protein kinase B.Q37170896
Bidirectional modulation of insulin action by amino acidsQ37380395
Differential effects of overexpression of PKC alpha and PKC delta/epsilon on cellular E2F activity in late G1 phaseQ38357962
Induction of differentiation in normal human keratinocytes by adenovirus-mediated introduction of the eta and delta isoforms of protein kinase C.Q39575845
Regulation of protein kinase C and role in cancer biology.Q40504332
Proliferation of human melanoma cells is under tight control of protein kinase C alphaQ40565036
ERK and p38 inhibit the expression of 4E-BP1 repressor of translation through induction of Egr-1.Q40666458
The potential of protein kinase C as a target for anticancer treatmentQ40815216
Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in miceQ40881142
Leucine regulates translation of specific mRNAs in L6 myoblasts through mTOR-mediated changes in availability of eIF4E and phosphorylation of ribosomal protein S6.Q40960220
Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cellsQ40972355
The role of protein kinase C alpha and epsilon isozymes in DNA synthesis induced by muscarinic receptors in a glial cell lineQ40991956
Protein kinase C isozyme-mediated cell cycle arrest involves induction of p21(waf1/cip1) and p27(kip1) and hypophosphorylation of the retinoblastoma protein in intestinal epithelial cellsQ41116723
Mechanism of action of rapamycin: new insights into the regulation of G1-phase progression in eukaryotic cellsQ41743877
Amino acid availability regulates p70 S6 kinase and multiple translation factorsQ41913722
Towards selective pharmacological modulation of protein kinase C--opportunities for the development of novel antineoplastic agentsQ42371610
PKCeta enhances cell cycle progression, the expression of G1 cyclins and p21 in MCF-7 cellsQ43800233
Distinct effects of bFGF and PDGF on oligodendrocyte progenitor cellsQ44238794
The inhibition of oligodendrocytic differentiation of O-2A progenitors caused by basic fibroblast growth factor is overridden by astrocytesQ48287949
Multiple routes to astrocytic differentiation in the CNS.Q48455897
PKCeta associates with cyclin E/cdk2/p21 complex, phosphorylates p21 and inhibits cdk2 kinase in keratinocytes.Q52585729
CNTF and its receptor subunits in human gliomas.Q55475931
The role of integrin receptors in aspects of glioma invasion in vitro.Q55476457
Expression of PDGF and PDGF receptors in human astrocytoma operation specimens supports the existence of an autocrine loop.Q55481185
The protein kinase C isoforms leading to MAP-kinase activation in CHO cellsQ71695037
P433issue56
P407language of work or nameEnglishQ1860
P921main subjectglioblastomaQ282142
P304page(s)9062-9069
P577publication date2004-12-01
P1433published inOncogeneQ1568657
P1476titlePKC-eta mediates glioblastoma cell proliferation through the Akt and mTOR signaling pathways
P478volume23

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