Phorbol 12-myristate 13-acetate and serum synergize to promote rapamycin-insensitive cell proliferation via protein kinase C-eta

scientific article

Phorbol 12-myristate 13-acetate and serum synergize to promote rapamycin-insensitive cell proliferation via protein kinase C-eta is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1019152547
P356DOI10.1038/SJ.ONC.1209791
P698PubMed publication ID16832347
P5875ResearchGate publication ID6953978

P2093author name stringMartin PM
Sturgill TW
Hussaini IM
Chrestensen CA
Aeder SE
P2860cites workPhorbol 12-myristate 13-acetate induces protein kinase ceta-specific proliferative response in astrocytic tumor cellsQ22254077
Protein kinase C-eta regulates resistance to UV- and gamma-irradiation-induced apoptosis in glioblastoma cells by preventing caspase-9 activationQ24292077
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeletonQ24299873
Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap functionQ24324452
RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1Q24682697
Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.Q27824772
TOR, a central controller of cell growthQ27933354
Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinasesQ28187456
Mechanisms of resistance to rapamycinsQ28198092
Phosphatidic acid-mediated mitogenic activation of mTOR signalingQ28208274
The role of protein kinase C in cell surface signal transduction and tumour promotionQ29618532
The molecular heterogeneity of protein kinase C and its implications for cellular regulationQ29619947
Regulation of translation initiation by FRAP/mTORQ29620398
PKC-eta mediates glioblastoma cell proliferation through the Akt and mTOR signaling pathwaysQ30434836
Requirements for therapeutic drug monitoring of sirolimus, an immunosuppressive agent used in renal transplantationQ33925685
4E-binding proteins, the suppressors of eukaryotic initiation factor 4E, are down-regulated in cells with acquired or intrinsic resistance to rapamycinQ34114303
Malignant glioma: genetics and biology of a grave matter.Q34272357
Transduction of growth or mitogenic signals into translational activation of TOP mRNAs is fully reliant on the phosphatidylinositol 3-kinase-mediated pathway but requires neither S6K1 nor rpS6 phosphorylationQ34286691
Efficient gene transfer into the human natural killer cell line, NKL, using the Amaxa nucleofection systemQ34291484
Tor signalling in bugs, brain and brawnQ35058522
Targeted molecular therapy of GBM.Q35064179
Molecular analysis of glioblastoma: pathway profiling and its implications for patient therapyQ35184074
PKC at a glance.Q35607952
Mammalian target of rapamycin (mTOR) InhibitorsQ35642619
The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinasesQ40020238
Determinants of rapamycin sensitivity in breast cancer cellsQ40590648
AKT activity determines sensitivity to mammalian target of rapamycin (mTOR) inhibitors by regulating cyclin D1 and c-myc expressionQ40623520
Spontaneous activation and signaling by overexpressed epidermal growth factor receptors in glioblastoma cellsQ40676718
The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain.Q40789796
Signal transduction pathways and their relevance in human astrocytomasQ40872114
Regulation of eIF-4E BP1 phosphorylation by mTOR.Q41087062
Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.Q41106936
Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sitesQ41666761
mTOR, a novel target in breast cancer: the effect of CCI-779, an mTOR inhibitor, in preclinical models of breast cancerQ42660087
Phospholipase D confers rapamycin resistance in human breast cancer cellsQ44482361
PKC alpha mediates chemoresistance in acute lymphoblastic leukemia through effects on Bcl2 phosphorylationQ44737480
Dysregulation of protein kinase C activity in chemoresistant metastatic breast cancer cellsQ44795619
Sirolimus-eluting stents in the canine cerebral vasculature: a prospective, randomized, blinded assessment of safety and vessel responseQ44834396
Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: a North Central Cancer Treatment Group StudyQ46585156
Oncogenic Ras and Akt Signaling Contribute to Glioblastoma Formation by Differential Recruitment of Existing mRNAs to PolysomesQ47421825
Functional and molecular analyses of 10q deletions in human gliomasQ48306512
Activation of the phosphatidylinositol-3'-kinase/protein kinase B-dependent antiapoptotic pathway plays an important role in the development of radioresistance of human glioma cellsQ48424881
Phosphatidic acid activation of protein kinase C in LA-N-1 neuroblastoma cellsQ71485279
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)407-414
P577publication date2006-07-10
P1433published inOncogeneQ1568657
P1476titlePhorbol 12-myristate 13-acetate and serum synergize to promote rapamycin-insensitive cell proliferation via protein kinase C-eta
P478volume26

Reverse relations

cites work (P2860)
Q42470449A Role for the Cavin-3/Matrix Metalloproteinase-9 Signaling Axis in the Regulation of PMA-Activated Human HT1080 Fibrosarcoma Cell Neoplastic Phenotype
Q92276992Inhibition of protein kinase C activity inhibits osteosarcoma metastasis
Q33389634Multivariate gene expression analysis reveals functional connectivity changes between normal/tumoral prostates
Q90285576PBX3/MEK/ERK1/2/LIN28/let-7b positive feedback loop enhances mesenchymal phenotype to promote glioblastoma migration and invasion
Q59072618Protein Kinase C (PKC) Isozymes and Cancer
Q35149607Tumor promoter-induced cellular senescence: cell cycle arrest followed by geroconversion

Search more.