| scholarly article | Q13442814 |
| P50 | author | Igor Olekhnovich | Q57201980 |
| P2093 | author name string | Paul S Hoffman | |
| Avery Goodwin | |||
| P2860 | cites work | Mutation discovery in bacterial genomes: metronidazole resistance in Helicobacter pylori. | Q50747378 |
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| Helicobacter pylori | Q24683623 | ||
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| Identification of a Mycobacterium tuberculosis putative classical nitroreductase gene whose expression is coregulated with that of the acr aene within macrophages, in standing versus shaking cultures, and under low oxygen conditions. | Q28486565 | ||
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| Sequential inactivation of rdxA (HP0954) and frxA (HP0642) nitroreductase genes causes moderate and high-level metronidazole resistance in Helicobacter pylori | Q33994585 | ||
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| The diverse antioxidant systems of Helicobacter pylori | Q34569491 | ||
| Metronidazole. A therapeutic review and update | Q34743506 | ||
| Identification of carboxylation enzymes and characterization of a novel four-subunit pyruvate:flavodoxin oxidoreductase from Helicobacter pylori | Q35589915 | ||
| From bench to bedside for gene-directed enzyme prodrug therapy of cancer | Q36061340 | ||
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| Mechanisms of flavoprotein-catalyzed reactions | Q38625599 | ||
| Metronidazole activation is mutagenic and causes DNA fragmentation in Helicobacter pylori and in Escherichia coli containing a cloned H. pylori RdxA(+) (Nitroreductase) gene | Q39500646 | ||
| Respiratory physiology and energy conservation efficiency of Campylobacter jejuni | Q39983894 | ||
| SIMPLE METHOD OF ANAEROBIC CULTIVATION, WITH REMOVAL OF OXYGEN BY A BUFFERED GLUCOSE OXIDASE-CATALASE SYSTEM. | Q40250808 | ||
| Synthesis and evaluation of nitroheterocyclic carbamate prodrugs for use with nitroreductase-mediated gene-directed enzyme prodrug therapy | Q40612485 | ||
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| Virus directed enzyme prodrug therapy for ovarian and pancreatic cancer using retrovirally delivered E. coli nitroreductase and CB1954. | Q40954656 | ||
| Quantitative structure-activity relationships in two-electron reduction of nitroaromatic compounds by Enterobacter cloacae NAD(P)H:nitroreductase | Q43613432 | ||
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| Experience with 'triple' anti-Helicobacter pylori eradication therapy: side effects and the importance of testing the pre-treatment bacterial isolate for metronidazole resistance. | Q44701699 | ||
| Escherichia coli-nitroreductase suicide gene control of human telomerase reverse transcriptase-transduced minor histocompatibility antigen-specific cytotoxic T cells | Q44817209 | ||
| Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme. | Q45246483 | ||
| Virus-directed enzyme prodrug therapy: intratumoral administration of a replication-deficient adenovirus encoding nitroreductase to patients with resectable liver cancer | Q45658005 | ||
| Combining gene and immunotherapy for prostate cancer | Q45870525 | ||
| Metronidazole resistance in Helicobacter pylori is due to null mutations in a gene (rdxA) that encodes an oxygen-insensitive NADPH nitroreductase | Q47986775 | ||
| Gene cloning, purification, and characterization of NfsB, a minor oxygen-insensitive nitroreductase from Escherichia coli, similar in biochemical properties to FRase I, the major flavin reductase in Vibrio fischeri | Q48059303 | ||
| Nitrocompound activation by cell-free extracts of nitroreductase-proficient Salmonella typhimurium strains. | Q50076811 | ||
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Helicobacter pylori infectious disease | Q4497153 |
| metronidazole | Q169569 | ||
| Helicobacter pylori | Q180556 | ||
| P304 | page(s) | 3354-3364 | |
| P577 | publication date | 2009-05-07 | |
| P1433 | published in | FEBS Journal | Q1388041 |
| P1476 | title | Characterization of the NAD(P)H oxidase and metronidazole reductase activities of the RdxA nitroreductase of Helicobacter pylori | |
| P478 | volume | 276 |
| Q49790580 | A review on metronidazole: an old warhorse in antimicrobial chemotherapy |
| Q34228648 | Activation of benznidazole by trypanosomal type I nitroreductases results in glyoxal formation |
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| Q30431893 | Biological activity of modified and exchanged 2-amino-5-nitrothiazole amide analogues of nitazoxanide |
| Q36745310 | Comparative characterisation of two nitroreductases from Giardia lamblia as potential activators of nitro compounds. |
| Q42120097 | Contingency nature of Helicobacter bizzozeronii oxygen-insensitive NAD(P)H-nitroreductase (HBZC1_00960) and its role in metronidazole resistance |
| Q44813678 | FrxA is an S-nitrosoglutathione reductase enzyme that contributes to Helicobacter pylori pathogenicity |
| Q33725381 | Functional analysis of the RdxA and RdxB nitroreductases of Campylobacter jejuni reveals that mutations in rdxA confer metronidazole resistance |
| Q43757938 | Lon protease affects the RdxA nitroreductase activity and metronidazole susceptibility in Helicobacter pylori |
| Q39769351 | Maximizing bactericidal activity with combinations of bioreduced drugs |
| Q45219788 | Metabolism of nitro drugs metronidazole and nitazoxanide in Giardia lamblia: characterization of a novel nitroreductase (GlNR2). |
| Q42678805 | Microevolution of a zoonotic Helicobacter population colonizing the stomach of a human host before and after failed treatment |
| Q37505662 | Molecular and Proteomic Analysis of Levofloxacin and Metronidazole Resistant Helicobacter pylori |
| Q54365687 | Nitroreductase (GlNR1) increases susceptibility of Giardia lamblia and Escherichia coli to nitro drugs. |
| Q30408277 | Preclinical studies of amixicile, a systemic therapeutic developed for treatment of Clostridium difficile infections that also shows efficacy against Helicobacter pylori |
| Q35096900 | Pyruvate:ferredoxin oxidoreductase and thioredoxin reductase are involved in 5-nitroimidazole activation while flavin metabolism is linked to 5-nitroimidazole resistance in Giardia lamblia |
| Q30411563 | Response to metronidazole and oxidative stress is mediated through homeostatic regulator HsrA (HP1043) in Helicobacter pylori |
| Q27674271 | Structure of RdxA--an oxygen-insensitive nitroreductase essential for metronidazole activation in Helicobacter pylori |
| Q30427797 | Synthesis and antimicrobial evaluation of nitazoxanide-based analogues: identification of selective and broad spectrum activity |
| Q37122487 | The Helicobacter pylori CZB Cytoplasmic Chemoreceptor TlpD Forms an Autonomous Polar Chemotaxis Signaling Complex That Mediates a Tactic Response to Oxidative Stress. |
| Q37707263 | Transcriptomics Indicates Active and Passive Metronidazole Resistance Mechanisms in Three Seminal Giardia Lines. |
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