Escherichia coli-nitroreductase suicide gene control of human telomerase reverse transcriptase-transduced minor histocompatibility antigen-specific cytotoxic T cells

scientific article published in May 2004

Escherichia coli-nitroreductase suicide gene control of human telomerase reverse transcriptase-transduced minor histocompatibility antigen-specific cytotoxic T cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/SJ.BMT.1704470
P698PubMed publication ID15048139
P5875ResearchGate publication ID8652967

P50authorTuna MutisQ110173510
Robert M VerdijkQ40247888
P2093author name stringBrand A
Goulmy E
Wilke M
Kloosterman A
Beslier V
P2860cites workHSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemiaQ45882160
Transfer of the human telomerase reverse transcriptase (TERT) gene into T lymphocytes results in extension of replicative potential.Q52018513
A Phase I/II Study of Herpes Simplex Virus Type 1 Thymidine Kinase “Suicide” Gene Therapy for Recurrent GlioblastomaQ58659735
Restoration of viral immunity in immunodeficient humans by the adoptive transfer of T cell clonesQ67518698
Antileukemic effect of chronic graft-versus-host disease: contribution to improved survival after allogeneic marrow transplantationQ70149552
Human telomerase and its regulationQ24533247
Specific Association of Human Telomerase Activity with Immortal Cells and CancerQ27860801
Rapid retroviral delivery of tetracycline-inducible genes in a single autoregulatory cassetteQ28776104
A survey of telomerase activity in human cancerQ29614858
A Fas-based suicide switch in human T cells for the treatment of graft-versus-host diseaseQ32061758
HLA class I-minor histocompatibility antigen tetramers select cytotoxic T cells with high avidity to the natural ligandQ34120965
Involvement of Fas (CD95/APO-1) and Fas ligand in apoptosis induced by ganciclovir treatment of tumor cells transduced with herpes simplex virus thymidine kinaseQ38322056
Antileukemic Effect of Graft-versus-Host Disease in Human Recipients of Allogeneic-Marrow GraftsQ39244446
Immortalization of human CD8+ T cell clones by ectopic expression of telomerase reverse transcriptaseQ40848482
Virus directed enzyme prodrug therapy for ovarian and pancreatic cancer using retrovirally delivered E. coli nitroreductase and CB1954.Q40954656
Increased bax expression is associated with cell death induced by ganciclovir in a herpes thymidine kinase gene-expressing glioma cell lineQ40964601
Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotypeQ40978432
Human minor histocompatibility antigens: new concepts for marrow transplantation and adoptive immunotherapyQ41561713
Replicative senescence of T cells: does the Hayflick Limit lead to immune exhaustion?Q41591692
The bystander effect of the nitroreductase/CB1954 enzyme/prodrug system is due to a cell-permeable metaboliteQ42801806
Administration of herpes simplex-thymidine kinase-expressing donor T cells with a T-cell-depleted allogeneic marrow graftQ43513924
Telomerase-specific suicide gene therapy vectors expressing bacterial nitroreductase sensitize human cancer cells to the pro-drug CB1954.Q43831003
Colocalization of retrovirus and target cells on specific fibronectin fragments increases genetic transduction of mammalian cellsQ44919142
Selective cell ablation in transgenic mice expression E. coli nitroreductaseQ45881111
The expression of bacterial nitroreductase in transgenic mice results in specific cell killing by the prodrug CB1954.Q45881144
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectEscherichia coliQ25419
P304page(s)963-967
P577publication date2004-05-01
P1433published inBone Marrow TransplantationQ4941523
P1476titleEscherichia coli-nitroreductase suicide gene control of human telomerase reverse transcriptase-transduced minor histocompatibility antigen-specific cytotoxic T cells
P478volume33

Reverse relations

cites work (P2860)
Q37634940Bystander or no bystander for gene directed enzyme prodrug therapy
Q30437743Characterization of the NAD(P)H oxidase and metronidazole reductase activities of the RdxA nitroreductase of Helicobacter pylori
Q46051134Conditional targeted cell ablation in zebrafish: a new tool for regeneration studies
Q54365687Nitroreductase (GlNR1) increases susceptibility of Giardia lamblia and Escherichia coli to nitro drugs.
Q37114805Reduction of polynitroaromatic compounds: the bacterial nitroreductases.
Q28073563Technical Considerations for the Generation of Adoptively Transferred T Cells in Cancer Immunotherapy

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