Restoration of viral immunity in immunodeficient humans by the adoptive transfer of T cell clones

scientific article published on July 10, 1992

Restoration of viral immunity in immunodeficient humans by the adoptive transfer of T cell clones is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1126/SCIENCE.1352912
P698PubMed publication ID1352912

P2093author name stringP. D. Greenberg
C. R. Li
S. R. Riddell
J. M. Goodrich
K. S. Watanabe
M. E. Agha
P433issue5067
P407language of work or nameEnglishQ1860
P1104number of pages4
P304page(s)238-241
P577publication date1992-07-01
1992-07-10
P1433published inScienceQ192864
P1476titleRestoration of viral immunity in immunodeficient humans by the adoptive transfer of T cell clones
P478volume257

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cites work (P2860)
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Q39871175Multiple independent loci within the human cytomegalovirus unique short region down-regulate expression of major histocompatibility complex class I heavy chains
Q33809769Murine model of interstitial cytomegalovirus pneumonia in syngeneic bone marrow transplantation: persistence of protective pulmonary CD8-T-cell infiltrates after clearance of acute infection
Q34729631Mutated PPP1R3B is recognized by T cells used to treat a melanoma patient who experienced a durable complete tumor regression.
Q26740328Mutual Interference between Cytomegalovirus and Reconstitution of Protective Immunity after Hematopoietic Cell Transplantation
Q47631107Mycobacterium tuberculosis-specific CD8+ T cells preferentially recognize heavily infected cells
Q55094448Novel Immunotherapy Options for Extranodal NK/T-Cell Lymphoma.
Q28730418Novel serial positive enrichment technology enables clinical multiparameter cell sorting
Q33713932Nucleofection of DCs to generate Multivirus-specific T cells for prevention or treatment of viral infections in the immunocompromised host.
Q64086953Opportunities to Target the Life Cycle of Epstein-Barr Virus (EBV) in EBV-Associated Lymphoproliferative Disorders
Q92643256Orthotopic replacement of T-cell receptor α- and β-chains with preservation of near-physiological T-cell function
Q38042835Parameters determining the efficacy of adoptive CD8 T-cell therapy of cytomegalovirus infection.
Q34300932Paths to stemness: building the ultimate antitumour T cell.
Q36377141Patterns of immunodominance in HIV-1-specific cytotoxic T lymphocyte responses in two human histocompatibility leukocyte antigens (HLA)-identical siblings with HLA-A*0201 are influenced by epitope mutation.
Q33703139Peptide vaccination in the presence of adjuvants in patients after hematopoietic stem cell transplantation with CD4+ T cell reconstitution elicits consistent CD8+ T cell responses
Q38353123Performance-enhancing drugs: design and production of redirected chimeric antigen receptor (CAR) T cells
Q52060127Peripheral clonal deletion of antiviral memory CD8+ T cells.
Q52010634Persistent lack of human herpesvirus-6 specific T-helper cell response in liver transplant recipients.
Q43433013Persistent rat cytomegalovirus (RCMV) infection of the salivary glands contributes to the anti-RCMV humoral immune response
Q36814589Pharmacotherapy versus T lymphocytes for CMV.
Q85157571Polyomavirus JC-targeted T-cell therapy for progressive multiple leukoencephalopathy in a hematopoietic cell transplantation recipient
Q47550219Posttransplant chimeric antigen receptor therapy
Q42151049Predictable alphabeta T-cell receptor selection toward an HLA-B*3501-restricted human cytomegalovirus epitope
Q33782273Preemptive CD8 T-cell immunotherapy of acute cytomegalovirus infection prevents lethal disease, limits the burden of latent viral genomes, and reduces the risk of virus recurrence
Q36315607Preliminary evidence that the novel host-derived immunostimulant EP67 can act as a mucosal adjuvant.
Q36453570Preparing clinical grade Ag-specific T cells for adoptive immunotherapy trials
Q35558815Prevention of Cytomegalovirus Disease in Recipients of Allogeneic Stem Cell Transplants
Q34339686Processing and presentation of murine cytomegalovirus pORFm164-derived peptide in fibroblasts in the face of all viral immunosubversive early gene functions
Q27314843Proliferation-linked apoptosis of adoptively transferred T cells after IL-15 administration in macaques
Q45116400Prophylaxis: the foundation for our future progress
Q35041705Prospects for immunotherapy of malignant disease
Q38926265Prospects of a vaccine for the prevention of congenital cytomegalovirus disease
Q73028738Quantification of replication of clinical cytomegalovirus isolates in cultured endothelial cells and fibroblasts by a focus expansion assay
Q33588711Re-adapting T cells for cancer therapy: from mouse models to clinical trials
Q28079823Recent Developments in Cellular Immunotherapy for HSCT-Associated Complications
Q37095341Recombinant viruses as tools to study human cytomegalovirus immune modulation
Q36999665Reconstitution of CD8 T Cells Protective against Cytomegalovirus in a Mouse Model of Hematopoietic Cell Transplantation: Dynamics and Inessentiality of Epitope Immunodominance.
Q83225298Reconstitution of CMV pp65 and IE-1-specific IFN-γ CD8(+) and CD4(+) T-cell responses affording protection from CMV DNAemia following allogeneic hematopoietic SCT
Q72059554Reconstitution of Cellular Immunity against Cytomegalovirus in Recipients of Allogeneic Bone Marrow by Transfer of T-Cell Clones from the Donor
Q81261927Reconstitution of HLA-A*2402-restricted cytomegalovirus-specific T-cells following stem cell transplantation
Q38931391Refining human T-cell immunotherapy of cytomegalovirus disease: a mouse model with 'humanized' antigen presentation as a new preclinical study tool
Q41866420Regression of metastatic Merkel cell carcinoma following transfer of polyomavirus-specific T cells and therapies capable of re-inducing HLA class-I
Q92621798Releasing the concept of HLA-allele specific peptide anchors in viral infections: A non-canonical naturally presented human cytomegalovirus-derived HLA-A*24:02 restricted peptide drives exquisite immunogenicity
Q36399914Repertoire, diversity, and differentiation of specific CD8 T cells are associated with immune protection against human cytomegalovirus disease
Q50097987Reprint of: Virus-Specific T Cells: Broadening Applicability
Q58657735Requirement for neutralizing antibodies to control bone marrow transplantation-associated persistent viral infection and to reduce immunopathology
Q42364280Retroviral transfer of T-cell receptor genes produces cells with a broad range of lytic activity
Q53940326Rev activity determines sensitivity of HIV-1-infected primary T cells to CTL killing.
Q34495529Reverse genetics modification of cytomegalovirus antigenicity and immunogenicity by CD8 T-cell epitope deletion and insertion
Q60029223Risk factors for treatment failures in patients receiving PCR-based preemptive therapy for CMV infection
Q58328348Role of Cellular Immunity in Protection against HIV Infection**This article was accepted for publication on 31 October 1996
Q57176933Role of Epstein-Barr Virus in the Pathogenesis of Head and Neck Cancers and Its Potential as an Immunotherapeutic Target
Q91774706Safety and feasibility of virus-specific T cells derived from umbilical cord blood in cord blood transplant recipients
Q33217629Selection of CMV-specific CD8+ and CD4+ T cells by mini-EBV-transformed B cell lines
Q37629901Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy.
Q36648290Selective interference with class I major histocompatibility complex presentation of the major immediate-early protein following infection with human cytomegalovirus.
Q35794646Separating antiviral and GVHD activities of donor T cells prior to bone marrow transplantation
Q40662000Serial in vivo imaging of the targeted migration of human HSV-TK-transduced antigen-specific lymphocytes
Q93104450Single-Cell Transcriptome Analysis Reveals Gene Signatures Associated with T-cell Persistence Following Adoptive Cell Therapy
Q27002575Sorting through subsets: which T-cell populations mediate highly effective adoptive immunotherapy?
Q34769333Stem cell-based anti-HIV gene therapy
Q61798868Strategies of adoptive T -cell transfer to treat refractory viral infections post allogeneic stem cell transplantation
Q36673260Subdominant CD8 T-cell epitopes account for protection against cytomegalovirus independent of immunodomination
Q36369054Substantial differences in specificity of HIV-specific cytotoxic T cells in acute and chronic HIV infection
Q53350069Summary of the II International Symposium on Cytomegalovirus.
Q73574832Suppression of human hepatoma in mice through adoptive transfer of immunity to the hepatitis B surface antigen
Q35068768Sustained complete responses in patients with lymphoma receiving autologous cytotoxic T lymphocytes targeting Epstein-Barr virus latent membrane proteins
Q30577136Synthetic control of mammalian-cell motility by engineering chemotaxis to an orthogonal bioinert chemical signal.
Q33845720Systemic hematogenous maintenance of memory inflation by MCMV infection.
Q34510551T cell immunotherapeutic populations control viral infections in bone marrow transplant recipients
Q93001461T cell receptor gene therapy targeting WT1 prevents acute myeloid leukemia relapse post-transplant
Q38815977T cell responses to cytomegalovirus
Q37382387T cell susceptibility to HIV influences outcome of opportunistic infections
Q36821993T cell therapies following hematopoietic stem cell transplantation: surely there must be a better way than DLI?
Q39898534T cells engineered with a cytomegalovirus-specific chimeric immunoreceptor.
Q37058107T cells for viral infections after allogeneic hematopoietic stem cell transplant
Q34414412T cells take aim at cancer
Q26786661T-Cell Therapy: Options for Infectious Diseases
Q92525198T-Scan: A Genome-wide Method for the Systematic Discovery of T Cell Epitopes
Q34550760T-bet:Eomes balance, effector function, and proliferation of cytomegalovirus-specific CD8+ T cells during primary infection differentiates the capacity for durable immune control
Q36234904T-cell genetic modification for re-directed tumor recognition.
Q45876112T-cell mediated rejection of gene-modified HIV-specific cytotoxic T lymphocytes in HIV-infected patients
Q36087036T-cell reconstitution and expansion after hematopoietic stem cell transplantation: 'T' it up!
Q37798704T-cell therapy for cytomegalovirus infection
Q36142522T-cell therapy for viral infections following transplantation: why stop at three viruses?
Q37220602Targeting cytomegalovirus-infected cells using T cells armed with anti-CD3 × anti-CMV bispecific antibody.
Q24670153Targeting of HIV-1 antigens for rapid intracellular degradation enhances cytotoxic T lymphocyte (CTL) recognition and the induction of de novo CTL responses in vivo after immunization
Q36116754The Cellular Localization of Human Cytomegalovirus Glycoprotein Expression Greatly Influences the Frequency and Functional Phenotype of Specific CD4+ T Cell Responses
Q39130457The Principles of Engineering Immune Cells to Treat Cancer
Q33734872The clinical and financial burden of pre-emptive management of cytomegalovirus disease after allogeneic stem cell transplantation-implications for preventative treatment approaches.
Q35477534The coming of age of adoptive T-cell therapy for viral infection after stem cell transplantation
Q36735379The continuing contribution of gene marking to cell and gene therapy.
Q41887918The efficacy of antigen processing is critical for protection against cytomegalovirus disease in the presence of viral immune evasion proteins.
Q36242361The human cytomegalovirus US6 glycoprotein inhibits transporter associated with antigen processing-dependent peptide translocation.
Q33970944The immunogenicity of human and murine cytomegaloviruses
Q27692570The immunological underpinnings of vaccinations to prevent cytomegalovirus disease
Q56917311The impact of HLA-B micropolymorphism outside primary peptide anchor pockets on the CTL response to CMV
Q73722298The impact of psychological stress on the efficacy of anti-viral adoptive immunotherapy in an immunocompromised host
Q36384707The impact of regulatory T cells on T-cell immunity following hematopoietic cell transplantation
Q35709655The many important facets of T-cell repertoire diversity
Q39551804The memory cytotoxic T-lymphocyte (CTL) response to human cytomegalovirus infection contains individual peptide-specific CTL clones that have undergone extensive expansion in vivo
Q38049899The next generation recombinant human cytomegalovirus vaccine candidates-beyond gB.
Q33797749The putative natural killer decoy early gene m04 (gp34) of murine cytomegalovirus encodes an antigenic peptide recognized by protective antiviral CD8 T cells
Q33781851The relative role of lymphocyte granule exocytosis versus death receptor-mediated cytotoxicity in viral pathophysiology
Q41435458The role of cytotoxic T lymphocytes in the evolution of genetically stable viruses
Q37592177The time is now: moving toward virus-specific T cells after allogeneic hematopoietic stem cell transplantation as the standard of care
Q61851835The use of Teflon cell culture bags to expand functionally active CD8+ cytotoxic T lymphocytes
Q41115110The use of computer-assisted video image analysis for the quantification of CD8+ T lymphocytes producing tumor necrosis factor alpha spots in response to peptide antigens
Q40199809Therapeutic T cell engineering
Q92735537Therapeutic advantages provided by banked virus-specific T-cells of defined HLA-restriction
Q27308832Therapeutic antiviral T cells noncytopathically clear persistently infected microglia after conversion into antigen-presenting cells
Q34786691Therapeutic cancer vaccines: are we there yet?
Q37333710Therapeutic memory T cells require costimulation for effective clearance of a persistent viral infection.
Q44026468Therapeutic vaccination against chronic viral infection: the importance of cooperation between CD4+ and CD8+ T cells
Q54321271Transfection of dendritic cells with in vitro-transcribed CMV RNA induces polyclonal CD8+- and CD4+-mediated CMV-specific T cell responses.
Q71803154Transfer of HIV-1-specific cytotoxic T lymphocytes to an AIDS patient leads to selection for mutant HIV variants and subsequent disease progression
Q41349219Transfer of myeloma idiotype-specific immunity from an actively immunised marrow donor
Q33811112Transfer of specificity for human immunodeficiency virus type 1 into primary human T lymphocytes by introduction of T-cell receptor genes
Q36919619Transferred WT1-reactive CD8+ T cells can mediate antileukemic activity and persist in post-transplant patients
Q35849686Transferred melanoma-specific CD8+ T cells persist, mediate tumor regression, and acquire central memory phenotype
Q36884194Translational mini-review series on infectious disease: congenital cytomegalovirus infection: 50 years on.
Q34554722Treatment of Epstein-Barr virus-associated malignancies with specific T cells
Q45472170Treatment of Epstein-Barr-virus-associated primary CNS B cell lymphoma with allogeneic T-cell immunotherapy and stem-cell transplantation
Q45730808Treatment of Epstein-Barr-virus-positive post-transplantation lymphoproliferative disease with partly HLA-matched allogeneic cytotoxic T cells
Q37419728Treatment of lymphoma with adoptively transferred T cells.
Q37808467Tumor vaccines and beyond
Q44696017Two types of CMV-specific memory responses in lung transplant recipients
Q38514503Umbilical cord blood graft engineering: challenges and opportunities.
Q37837487Understanding human T-cell-mediated immunoregulation through herpesviruses
Q44618759Use of gene-modified virus-specific T lymphocytes to control Epstein-Barr-virus-related lymphoproliferation
Q35751946Vaccine properties of a novel marker gene-free recombinant modified vaccinia Ankara expressing immunodominant CMV antigens pp65 and IE1.
Q52717409Validation of a CD1b tetramer assay for studies of human mycobacterial infection or vaccination.
Q24646943Viral immune evasion due to persistence of activated T cells without effector function
Q35962532Viral prophylaxis in organ transplant patients
Q38074019Viral-specific adoptive immunotherapy after allo-SCT: the role of multimer-based selection strategies
Q98291353Virus-Specific T Cell Therapies for HIV: Lessons Learned From Hematopoietic Stem Cell Transplantation
Q45326335Virus-Specific T Cells: Broadening Applicability
Q38797555Virus-specific T-cell banks for 'off the shelf' adoptive therapy of refractory infections
Q83139492[131I]FIAU labeling of genetically transduced, tumor-reactive lymphocytes: cell-level dosimetry and dose-dependent toxicity

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