Therapeutic vaccination against chronic viral infection: the importance of cooperation between CD4+ and CD8+ T cells

scientific article

Therapeutic vaccination against chronic viral infection: the importance of cooperation between CD4+ and CD8+ T cells is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1016/S0952-7915(98)80119-2
P698PubMed publication ID9722921
P5875ResearchGate publication ID13562472

P2093author name stringAhmed R
Murali-Krishna K
Zajac AJ
Blattman JN
P2860cites workCounting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection.Q52040367
Neonatal Tolerance Revisited: Turning on Newborn T Cells with Dendritic CellsQ56338635
An Essential Role for Type 1 Interferon-γ in Terminating Persistent Viral InfectionQ58828960
Restoration of viral immunity in immunodeficient humans by the adoptive transfer of T cell clonesQ67518698
Transfer of HIV-1-specific cytotoxic T lymphocytes to an AIDS patient leads to selection for mutant HIV variants and subsequent disease progressionQ71803154
CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clonesQ28209894
Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremiaQ28254584
Phenotypic analysis of antigen-specific T lymphocytesQ28290058
Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient miceQ28594763
Tolerance, danger, and the extended familyQ29547532
Principles for adoptive T cell therapy of human viral diseasesQ34300059
Immune function in mice lacking the perforin geneQ35882128
Uncovering subdominant cytotoxic T-lymphocyte responses in lymphocytic choriomeningitis virus-infected BALB/c mice.Q35887911
Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunityQ36366051
Progressive loss of CD8+ T cell-mediated control of a gamma-herpesvirus in the absence of CD4+ T cellsQ36367286
Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes.Q36400784
Enhanced establishment of a virus carrier state in adult CD4+ T-cell-deficient mice.Q36623371
CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infectionQ36637922
Immune therapy of a persistent and disseminated viral infection.Q36920380
Massive expansion of antigen-specific CD8+ T cells during an acute virus infectionQ37419599
Virus-triggered acquired immunodeficiency by cytotoxic T-cell-dependent destruction of antigen-presenting cells and lymph follicle structureQ37595741
Generation, translocation, and presentation of MHC class I-restricted peptidesQ40422033
Hepatitis B virus immunopathogenesisQ40444875
Large clonal expansions of CD8+ T cells in acute infectious mononucleosisQ40665903
Origin, maturation and antigen presenting function of dendritic cells.Q40906220
Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivoQ41039693
To kill or to cure: options in host defense against viral infection.Q41103038
The cell-mediated immune response against lymphocytic choriomeningitis virus in beta 2-microglobulin deficient miceQ41126124
Cytokine-induced differentiation of precursor mouse CD8+ T cells into cytotoxic CD8+ T cells secreting Th1 or Th2 cytokines.Q41365854
Functions of CD8 T-cell subsets secreting different cytokine patterns.Q41508127
Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4Q41589138
Viral strategies of immune evasionQ41735903
Direct visualization of antigen-specific CD8+ T cells during the primary immune response to Epstein-Barr virus In vivoQ41764334
A new look at T cellsQ41896404
Protection of adult but not newborn mice against lethal intracerebral challenge with Japanese encephalitis virus by adoptively transferred virus-specific cytotoxic T lymphocytes: requirement for L3T4+ T cellsQ42977014
Tumor Rejection After Direct Costimulation of CD8 + T Cells by B7-Transfected Melanoma CellsQ44615042
Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cellsQ45151385
Virus-specific CD8+ T cells in primary and secondary influenza pneumoniaQ45755057
Long-term restoration of immunity against Epstein-Barr virus infection by adoptive transfer of gene-modified virus-specific T lymphocytesQ45771097
Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytesQ45771892
Immune exhaustion: driving virus-specific CD8+ T cells to deathQ45779190
T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactionsQ47982736
Help for cytotoxic-T-cell responses is mediated by CD40 signallingQ47982749
A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cellQ47982760
P433issue4
P921main subjectcooperationQ380962
P304page(s)444-449
P577publication date1998-08-01
P1433published inCurrent Opinion in ImmunologyQ15752917
P1476titleTherapeutic vaccination against chronic viral infection: the importance of cooperation between CD4+ and CD8+ T cells
P478volume10

Reverse relations

cites work (P2860)
Q36958112A Phase I vaccine trial using dendritic cells pulsed with autologous oxidized lysate for recurrent ovarian cancer.
Q36189261A placebo-controlled randomized HPV16 synthetic long-peptide vaccination study in women with high-grade cervical squamous intraepithelial lesions
Q40896159A repetitive sequence of Epstein-Barr virus nuclear antigen 6 comprises overlapping T cell epitopes which induce HLA-DR-restricted CD4(+) T lymphocytes
Q34842204All in the head: obstacles for immune rejection of brain tumours
Q48152277Astrocytoma infiltrating lymphocytes include major T cell clonal expansions confined to the CD8 subset.
Q36643661Autologous lysate-pulsed dendritic cell vaccination followed by adoptive transfer of vaccine-primed ex vivo co-stimulated T cells in recurrent ovarian cancer.
Q37460652CD4(+) T-cell engagement by both wild-type and variant HCV peptides modulates the conversion of viral clearing helper T cells to Tregs
Q35219026Cancer vaccines: between the idea and the reality
Q44996566Cellular immune responses to feline immunodeficiency virus (FIV) induced by dual-subtype FIV vaccine
Q34342413Characterization of human immunodeficiency virus type 1 (HIV-1) Gag- and Gag peptide-specific CD4(+) T-cell clones from an HIV-1-seronegative donor following in vitro immunization
Q39169715Cyclopeptide scaffolds in carbohydrate-based synthetic vaccines
Q42642562Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell Help
Q33811983Diminished primary and secondary influenza virus-specific CD8(+) T-cell responses in CD4-depleted Ig(-/-) mice.
Q44946314Efficacy of hepatitis B vaccination and interferon-alpha-2b combination therapy versus interferon-alpha-2b monotherapy in children with chronic hepatitis B.
Q44448449Enhanced cellular immune response against SIV Gag induced by immunization with DNA vaccines expressing assembly and release-defective SIV Gag proteins
Q74080209Expression of perforin on HIV-1-specific CD8+ lymphocytes after immunization with a gp120-depleted, whole-killed HIV-1 immunogen
Q35826514Genetic modification of T lymphocytes for adoptive immunotherapy
Q33574329Human Immunodeficiency Virus and Human Papilloma Virus - why HPV-induced lesions do not spontaneously resolve and why therapeutic vaccination can be successful
Q35731386Identification of naturally processed and HLA-presented Epstein-Barr virus peptides recognized by CD4(+) or CD8(+) T lymphocytes from human blood.
Q37406571Immune targeting of PD-1(hi) expressing cells during and after antiretroviral therapy in SIV-infected rhesus macaques
Q37620833Immunological and antiviral responses after therapeutic DNA immunization in chronic hepatitis B patients efficiently treated by analogues.
Q33905225Immunological memory and acquired immunodeficiency syndrome pathogenesis
Q51019176Impact of inducible co-stimulatory molecule (ICOS) on T-cell responses and protection against Mycobacterium tuberculosis infection.
Q43276074Implication of Th17 and Th1 cells in patients with chronic active hepatitis B.
Q36358909Incidence and clearance of anal high-risk human papillomavirus in HIV-positive men who have sex with men: estimates and risk factors
Q34856857Induction and function of virus-specific CD4+ T cell responses
Q40855997Induction of CTL response by a minimal epitope vaccine in HLA A*0201/DR1 transgenic mice: dependence on HLA class II restricted T(H) response.
Q42233712Interference with PD-L1/PD-1 co-stimulation during antigen presentation enhances the multifunctionality of antigen-specific T cells
Q33287802Interleukin-10 plays an early role in generating virus-specific T cell anergy
Q40628602Intratumor CpG-Oligodeoxynucleotide Injection Induces Protective Antitumor T Cell Immunity
Q37118150Multiple roles for CD4+ T cells in anti-tumor immune responses
Q34913212Naturally occurring CD4+ T-cell epitope variants act as altered peptide ligands leading to impaired helper T-cell responses in hepatitis C virus infection
Q33847673Role of CD8(+) lymphocytes in control of simian immunodeficiency virus infection and resistance to rechallenge after transient early antiretroviral treatment
Q34466498Role of PD-1 co-inhibitory pathway in HIV infection and potential therapeutic options
Q81690451Self HSP60 peptide serves as an immunogenic carrier for a CTL epitope against persistence of murine cytomegalovirus in the salivary gland
Q62129133Subtype AE HIV-1 DNA and recombinant Fowlpoxvirus vaccines encoding five shared HIV-1 genes: safety and T cell immunogenicity in macaques
Q33977826Success or failure of vaccination for HPV16-positive vulvar lesions correlates with kinetics and phenotype of induced T-cell responses
Q34981964T cell responses to viral infections: lessons from lymphocytic choriomeningitis virus
Q35073666T helper lymphocytes rescue CTL from activation-induced cell death
Q34228659Th-cytotoxic T-lymphocyte chimeric epitopes extended by Nepsilon-palmitoyl lysines induce herpes simplex virus type 1-specific effector CD8+ Tc1 responses and protect against ocular infection
Q42255546The long-term immune response after HPV16 peptide vaccination in women with low-grade pre-malignant disorders of the uterine cervix: a placebo-controlled phase II study
Q33748013The makings of a tumor rejection antigen
Q80038678The promise of cancer vaccines
Q34232543The role of MHC class II-restricted tumor antigens and CD4+ T cells in antitumor immunity
Q45429014Therapeutic vaccination with papillomavirus E6 and E7 long peptides results in the control of both established virus-induced lesions and latently infected sites in a pre-clinical cottontail rabbit papillomavirus model
Q41316816Tumor-infiltrating T lymphocytes improve clinical outcome of therapy-resistant neuroblastoma
Q35150143Vaccine-induced immunity in baboons by using DNA and replication-incompetent adenovirus type 5 vectors expressing a human immunodeficiency virus type 1 gag gene
Q36900143Vaccines to prevent chronic hepatitis C virus infection: current experimental and preclinical developments

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