Molecules and mechanisms of the graft-versus-leukaemia effect

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Molecules and mechanisms of the graft-versus-leukaemia effect is …
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scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1042309842
P356DOI10.1038/NRC1365
P698PubMed publication ID15122208

P2093author name stringStanley R Riddell
Marie Bleakley
P2860cites workIn situ dissection of the graft-versus-host activities of cytotoxic T cells specific for minor histocompatibility antigensQ77859052
Tetrameric HLA class I-minor histocompatibility antigen peptide complexes demonstrate minor histocompatibility antigen-specific cytotoxic T lymphocytes in patients with graft-versus-host diseaseQ77966217
Identification of a polymorphic gene, BCL2A1, encoding two novel hematopoietic lineage-specific minor histocompatibility antigensQ24673417
The immunogenicity of a new human minor histocompatibility antigen results from differential antigen processingQ24675797
Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytesQ24676216
Reliable prediction of T-cell epitopes using neural networks with novel sequence representationsQ27485882
The minor histocompatibility antigen HA-3 arises from differential proteasome-mediated cleavage of the lymphoid blast crisis (Lbc) oncoproteinQ28187004
WT1 proteins: functions in growth and differentiationQ28191433
Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplantsQ29619458
A human minor histocompatibility antigen specific for B cell acute lymphoblastic leukemia.Q30274634
The HA-2 minor histocompatibility antigen is derived from a diallelic gene encoding a novel human class I myosin protein.Q30307859
Human H-Y: a male-specific histocompatibility antigen derived from the SMCY proteinQ30464516
The HLA-A*0201-restricted H-Y antigen contains a posttranslationally modified cysteine that significantly affects T cell recognitionQ30470188
The genetic program of hematopoietic stem cellsQ30874287
A Fas-based suicide switch in human T cells for the treatment of graft-versus-host diseaseQ32061758
Allografting with nonmyeloablative conditioning following cytoreductive autografts for the treatment of patients with multiple myelomaQ33348936
Transfer of specificity for human immunodeficiency virus type 1 into primary human T lymphocytes by introduction of T-cell receptor genesQ33811112
The human UTY gene encodes a novel HLA-B8-restricted H-Y antigen.Q33890464
The HLA system. First of two partsQ34023681
Harnessing graft-versus-malignancy: non-myeloablative preparative regimens for allogeneic haematopoietic transplantation, an evolving strategy for adoptive immunotherapyQ34089112
Understanding dendritic cell and T-lymphocyte traffic through the analysis of chemokine receptor expressionQ34118755
The DBY gene codes for an HLA-DQ5-restricted human male-specific minor histocompatibility antigen involved in graft-versus-host disease.Q34121730
Graft-versus-host disease after nonmyeloablative versus conventional hematopoietic stem cell transplantationQ34186689
Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: in vivo persistence, migration, and antitumor effect of transferred T cellsQ34415738
Expression of cutaneous lymphocyte-associated antigen by CD8(+) T cells specific for a skin-tropic virusQ34777218
Hematopoiesis-restricted minor histocompatibility antigens HA-1- or HA-2-specific T cells can induce complete remissions of relapsed leukemiaQ34808353
Pathogenesis and treatment of graft-versus-host disease after bone marrow transplantQ34931009
The current status of hematopoietic cell transplantationQ34987985
Alloreactive killer cells: hindrance and help for haematopoietic transplantsQ35058540
Adoptive-cell-transfer therapy for the treatment of patients with cancerQ35210008
Minor histocompatibility antigens in human stem cell transplantationQ35214671
CD8(+) minor histocompatibility antigen-specific cytotoxic T lymphocyte clones eliminate human acute myeloid leukemia stem cellsQ35558987
Growth inhibition of clonogenic leukemic precursor cells by minor histocompatibility antigen-specific cytotoxic T lymphocytesQ36230215
A human minor histocompatibility antigen resulting from differential expression due to a gene deletionQ36370375
Antileukemic Effect of Graft-versus-Host Disease in Human Recipients of Allogeneic-Marrow GraftsQ39244446
Chronic myelogenous leukemia shapes host immunity by selective deletion of high-avidity leukemia-specific T cells.Q39741064
Transfer of allogeneic CD62L- memory T cells without graft-versus-host diseaseQ40627364
Bi-directional allelic recognition of the human minor histocompatibility antigen HB-1 by cytotoxic T lymphocytesQ40700703
Identification of a novel HLA-B60-restricted T cell epitope of the minor histocompatibility antigen HA-1 locusQ40705556
Identification of a novel WT1-derived peptide which induces human leucocyte antigen-A24-restricted anti-leukaemia cytotoxic T lymphocytesQ40750584
Circumventing tolerance to a human MDM2-derived tumor antigen by TCR gene transferQ40777946
Identification of human telomerase reverse transcriptase-derived peptides that induce HLA-A24-restricted antileukemia cytotoxic T lymphocytesQ40811313
The minor histocompatibility antigen HA-1: a diallelic gene with a single amino acid polymorphism.Q41061835
Nonablative allogeneic hematopoietic transplantation as adoptive immunotherapy for indolent lymphoma: low incidence of toxicity, acute graft-versus-host disease, and treatment-related mortalityQ43819629
Interferon-alpha, but not the ABL-kinase inhibitor imatinib (STI571), induces expression of myeloblastin and a specific T-cell response in chronic myeloid leukemiaQ44189831
HLA-matched unrelated donor hematopoietic cell transplantation after nonmyeloablative conditioning for patients with hematologic malignanciesQ44468881
Frequency of major molecular responses to imatinib or interferon alfa plus cytarabine in newly diagnosed chronic myeloid leukemiaQ44611047
Long-term restoration of immunity against Epstein-Barr virus infection by adoptive transfer of gene-modified virus-specific T lymphocytesQ45771097
A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiencyQ45857796
T-cell mediated rejection of gene-modified HIV-specific cytotoxic T lymphocytes in HIV-infected patientsQ45876112
HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemiaQ45882160
Disparity for a newly identified minor histocompatibility antigen, HA-8, correlates with acute graft-versus-host disease after haematopoietic stem cell transplantation from an HLA-identical sibling.Q47385454
Pharmacologically regulated Fas-mediated death of adoptively transferred T cells in a nonhuman primate model.Q47438492
Graft-versus-leukemia effects in T lineage and B lineage acute lymphoblastic leukemiaQ47626366
Female donors contribute to a selective graft-versus-leukemia effect in male recipients of HLA-matched, related hematopoietic stem cell transplantsQ47631013
Induction of cytotoxic T-cell responses against the oncofetal antigen-immature laminin receptor for the treatment of hematologic malignanciesQ47752014
Human cytotoxic T lymphocytes specific for Wilms' tumor antigen-1 inhibit engraftment of leukemia-initiating stem cells in non-obese diabetic-severe combined immunodeficient recipientsQ47853618
In vivo migration and function of transferred HIV-1-specific cytotoxic T cellsQ47995100
Functional leukemia-associated antigen-specific memory CD8+ T cells exist in healthy individuals and in patients with chronic myelogenous leukemia before and after stem cell transplantation.Q52006998
Adoptive tumor therapy with T lymphocytes enriched through an IFN-gamma capture assay.Q52961647
Eradication of systemic B-cell tumors by genetically targeted human T lymphocytes co-stimulated by CD80 and interleukin-15.Q53659254
Abnormal expression of apoptosis-related genes in haematological malignancies: overexpression of MYC is poor prognostic sign in mantle cell lymphoma.Q54790078
Treatment of murine leukaemia with X rays and homologous bone marrow; preliminary communication.Q55510169
Identification of a graft versus host disease-associated human minor histocompatibility antigenQ56929110
The shared tumor-associated antigen cytochrome P450 1B1 is recognized by specific cytotoxic T cellsQ57556495
Regression of Metastatic Renal-Cell Carcinoma after Nonmyeloablative Allogeneic Peripheral-Blood Stem-Cell TransplantationQ64038880
Restoration of viral immunity in immunodeficient humans by the adoptive transfer of T cell clonesQ67518698
Mismatches of minor histocompatibility antigens between HLA-identical donors and recipients and the development of graft-versus-host disease after bone marrow transplantationQ70812614
Reconstitution of Cellular Immunity against Cytomegalovirus in Recipients of Allogeneic Bone Marrow by Transfer of T-Cell Clones from the DonorQ72059554
Immunocytochemical and flow cytometric detection of proteinase 3 (myeloblastin) in normal and leukaemic myeloid cellsQ72585119
Donor leukocyte infusions in 140 patients with relapsed malignancy after allogeneic bone marrow transplantationQ73117300
Redirection of antileukemic reactivity of peripheral T lymphocytes using gene transfer of minor histocompatibility antigen HA-2-specific T-cell receptor complexes expressing a conserved alpha joining regionQ73686876
Identification of HLA class II-restricted H-Y-specific T-helper epitope evoking CD4+ T-helper cells in H-Y-mismatched transplantationQ73874939
Adoptive transfer of minor histocompatibility antigen-specific T lymphocytes eradicates leukemia cells without causing graft-versus-host diseaseQ74122363
Acute graft-versus-host disease does not require alloantigen expression on host epitheliumQ74221421
Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemiaQ74268543
Induction of HA-1-specific cytotoxic T-cell clones parallels the therapeutic effect of donor lymphocyte infusionQ74284634
Generation of bcr-abl specific cytotoxic T-lymphocytes by using dendritic cells pulsed with bcr-abl (b3a2) peptide: its applicability for donor leukocyte transfusions in marrow grafted CML patientsQ74456064
Efficient induction of minor histocompatibility antigen HA-1-specific cytotoxic T-cells using dendritic cells retrovirally transduced with HA-1-coding cDNAQ74794179
Absence of statistically significant correlation between disparity for the minor histocompatibility antigen-HA-1 and outcome after allogeneic hematopoietic cell transplantationQ77228594
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
P304page(s)371-380
P577publication date2004-05-01
P1433published inNature Reviews CancerQ641657
P1476titleMolecules and mechanisms of the graft-versus-leukaemia effect
P478volume4

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