Large functional repertoire of regulatory T-cell suppressible autoimmune T cells in scurfy mice

scientific article

Large functional repertoire of regulatory T-cell suppressible autoimmune T cells in scurfy mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.JAUT.2007.04.001
P932PMC publication ID2099300
P698PubMed publication ID17521882
P5875ResearchGate publication ID6310700

P50authorShu Man FuQ57174082
Rahul SharmaQ57432005
Shyr-Te JuQ70422514
P2093author name stringFelicia Gaskin
Lingjie Zheng
Wael N Jarjour
P2860cites workWhere FoxP3-dependent regulatory T cells impinge on the development of inflammatory arthritisQ58228376
Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expressionQ59048389
Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor betaQ72287439
Impact of negative selection on the T cell repertoire reactive to a self-peptide: a large fraction of T cell clones escapes clonal deletionQ73406538
Pancreatic lymph node-derived CD4(+)CD25(+) Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signalsQ77704341
Origin and T cell receptor diversity of Foxp3+CD4+CD25+ T cellsQ80034250
Control of autoimmune myocarditis and multiorgan inflammation by glucocorticoid-induced TNF receptor family-related protein(high), Foxp3-expressing CD25+ and CD25- regulatory T cellsQ83059351
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouseQ24290693
Development and function of T cells in mice rendered interleukin-2 deficient by gene targetingQ24318910
Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndromeQ24679039
Foxp3 programs the development and function of CD4+CD25+ regulatory T cellsQ27860714
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseasesQ28131652
Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory diseaseQ28202655
Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4Q28284177
How defects in central tolerance impinge on a deficiency in regulatory T cellsQ28511833
Cellular and molecular characterization of the scurfy mouse mutantQ28513849
Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartmentQ28587823
An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoiresQ28590409
Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasisQ29547656
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfyQ29619109
Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of miceQ29622850
Novel animal models for Sjögren's syndrome: expression and transfer of salivary gland dysfunction from regulatory T cell-deficient miceQ30414128
Continuous control of autoimmune disease by antigen-dependent polyclonal CD4+CD25+ regulatory T cells in the regional lymph nodeQ30438088
Neonates support lymphopenia-induced proliferation.Q34170899
Cutting edge: cure of colitis by CD4+CD25+ regulatory T cellsQ34189120
Thymus and Reproduction: Sex-Linked Dysgenesia of the Gonad after Neonatal Thymectomy in MiceQ34705919
Naturally-occurring CD4+CD25+ immunoregulatory T cells: central players in the arena of peripheral toleranceQ35703487
Murine autoimmune oophoritis, epididymoorchitis, and gastritis induced by day 3 thymectomy. ImmunopathologyQ35855856
Lack of Foxp3 function and expression in the thymic epitheliumQ36267143
How do CD4+CD25+ regulatory T cells control autoimmunity?Q36279165
Innate cellular immune responses in newbornsQ36353231
Emerging possibilities in the development and function of regulatory T cellsQ36486882
Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecificQ40910998
Expression of self-antigen in the thymus: a little goes a long way.Q42090814
Autoreactive T cells in healthy individualsQ44885053
Rescue of the autoimmune scurfy mouse by partial bone marrow transplantation or by injection with T-enriched splenocytesQ45863745
Autoreactive T cells revealed in the normal repertoire: escape from negative selection and peripheral tolerance.Q52122341
Tolerogenic semimature dendritic cells suppress experimental autoimmune thyroiditis by activation of thyroglobulin-specific CD4+CD25+ T cellsQ56902811
Specific T regulatory cells display broad suppressive functions against experimental allergic encephalomyelitis upon activation with cognate antigenQ56902816
P433issue1
P304page(s)10-19
P577publication date2007-05-23
P1433published inJournal of AutoimmunityQ15716783
P1476titleLarge functional repertoire of regulatory T-cell suppressible autoimmune T cells in scurfy mice
P478volume29

Reverse relations

cites work (P2860)
Q30419044A novel function of IL-2: chemokine/chemoattractant/retention receptor genes induction in Th subsets for skin and lung inflammation
Q30423284A novel role of IL-2 in organ-specific autoimmune inflammation beyond regulatory T cell checkpoint: both IL-2 knockout and Fas mutation prolong lifespan of Scurfy mice but by different mechanisms
Q33661671Aberrant muscle antigen exposure in mice is sufficient to cause myositis in a Treg cell-deficient milieu
Q55103599Activation of CD4 and CD8 T cell receptors and regulatory T cells in response to human proteins.
Q34276576Cell-permeable Foxp3 protein alleviates autoimmune disease associated with inflammatory bowel disease and allergic airway inflammation.
Q46321148Clinical heterogeneity of immunodysregulation, polyendocrinopathy, enteropathy, X-linked: pulmonary involvement as a non-classical disease manifestation
Q37182941Etiopathogenesis of primary biliary cirrhosis
Q54530995FOXP3 expression in human kidney transplant biopsies is associated with rejection and time post transplant but not with favorable outcomes.
Q35541507Gene expression profiling in acute allograft rejection: challenging the immunologic constant of rejection hypothesis
Q30431210Genetic control of the inflammatory T-cell response in regulatory T-cell deficient scurfy mice
Q90941547Helios+ and Helios- Treg subpopulations are phenotypically and functionally distinct and express dissimilar TCR repertoires
Q30435491IL-2 regulates CD103 expression on CD4+ T cells in Scurfy mice that display both CD103-dependent and independent inflammation
Q30252348IL233, A Novel IL-2 and IL-33 Hybrid Cytokine, Ameliorates Renal injury
Q36843721Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells
Q30436735Pervasive and stochastic changes in the TCR repertoire of regulatory T-cell-deficient mice
Q30437887Rapid and selective expansion of nonclonotypic T cells in regulatory T cell-deficient, foreign antigen-specific TCR-transgenic scurfy mice: antigen-dependent expansion and TCR analysis
Q30440063Regulation of multi-organ inflammation in the regulatory T cell-deficient scurfy mice
Q35344378Regulatory T cell-deficient scurfy mice develop systemic autoimmune features resembling lupus-like disease
Q45066685Regulatory T cells in Acute and Chronic Kidney Diseases
Q30435312Regulatory T cells suppress innate immunity in kidney ischemia-reperfusion injury
Q41855339Species-specific immune responses generated by histidyl-tRNA synthetase immunization are associated with muscle and lung inflammation
Q43110424T-bet regulates differentiation of forkhead box protein 3+ regulatory T cells in programmed cell death-1-deficient mice
Q30413157The Biology of Autoimmune Response in the Scurfy Mice that Lack the CD4+Foxp3+ Regulatory T-Cells
Q36938320The Peyer's patch is a critical immunoregulatory site for mucosal tolerance in experimental autoimmune encephalomylelitis (EAE)
Q33826322The forkhead transcription factor, FOXP3: a critical role in male fertility in mice
Q30434942X-linked Foxp3 (Scurfy) mutation dominantly inhibits submandibular gland development and inflammation respectively through adaptive and innate immune mechanisms
Q36553627γδ T Cells Protect the Liver and Lungs of Mice from Autoimmunity Induced by Scurfy Lymphocytes

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