Reelin supplementation recovers sensorimotor gating, synaptic plasticity and associative learning deficits in the heterozygous reeler mouse

scientific article

Reelin supplementation recovers sensorimotor gating, synaptic plasticity and associative learning deficits in the heterozygous reeler mouse is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1177/0269881112463468
P932PMC publication ID3820099
P698PubMed publication ID23104248

P50authorEdwin J WeeberQ92958180
P2093author name stringG William Rebeck
Hyang-Sook Hoe
Jessica L Banko
Qingyou Li
Gabriella D'Arcangelo
Justin H Trotter
Melinda M Peters
Lisa Zhao
Justin T Rogers
Erika Donaldson
Ian Rusiana
Kathleen E Keenoy
P2860cites workDirect binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylationQ22010836
On the epigenetic regulation of the human reelin promoterQ24533209
Reelin expression and glycosylation patterns are altered in Alzheimer's diseaseQ24541523
Regulation of protein tyrosine kinase signaling by substrate degradation during brain developmentQ24633286
The Reelin signaling pathway promotes dendritic spine development in hippocampal neuronsQ24648455
Reelin signaling antagonizes beta-amyloid at the synapseQ24651028
A decrease of reelin expression as a putative vulnerability factor in schizophreniaQ24657918
Cortical bitufted, horizontal, and Martinotti cells preferentially express and secrete reelin into perineuronal nets, nonsynaptically modulating gene expressionQ24672235
Colocalization of integrin receptors and reelin in dendritic spine postsynaptic densities of adult nonhuman primate cortexQ24677027
Reelin is preferentially expressed in neurons synthesizing gamma-aminobutyric acid in cortex and hippocampus of adult ratsQ24685255
Structure-stability-function relationships of dendritic spinesQ28185845
Reelin and ApoE receptors cooperate to enhance hippocampal synaptic plasticity and learningQ28217153
Reelin haploinsufficiency reduces the density of PV+ neurons in circumscribed regions of the striatum and selectively alters striatal-based behaviorsQ28237853
Reelin and apoE actions on signal transduction, synaptic function and memory formationQ28254650
DAB1 and Reelin effects on amyloid precursor protein and ApoE receptor 2 trafficking and processingQ28261752
Functional dissection of Reelin signaling by site-directed disruption of Disabled-1 adaptor binding to apolipoprotein E receptor 2: distinct roles in development and synaptic plasticityQ28297694
Gating and habituation of the startle reflex in schizophrenic patientsQ28304417
Dendritic spine geometry is critical for AMPA receptor expression in hippocampal CA1 pyramidal neuronsQ28363018
Reelin supplementation enhances cognitive ability, synaptic plasticity, and dendritic spine densityQ28504750
Modulation of synaptic plasticity and memory by Reelin involves differential splicing of the lipoprotein receptor Apoer2Q28566778
Reelin regulates postnatal neurogenesis and enhances spine hypertrophy and long-term potentiationQ28585624
Reelin in the extracellular matrix and dendritic spines of the cortex and hippocampus: a comparison between wild type and heterozygous reeler mice by immunoelectron microscopyQ28590563
Dendritic spine changes associated with hippocampal long-term synaptic plasticityQ29614373
Shrinkage of dendritic spines associated with long-term depression of hippocampal synapsesQ29615872
Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain studyQ29616193
A protein related to extracellular matrix proteins deleted in the mouse mutant reelerQ29618965
Experience-dependent structural synaptic plasticity in the mammalian brainQ29619661
Rapid Dendritic Morphogenesis in CA1 Hippocampal Dendrites Induced by Synaptic ActivityQ29997835
Synaptic interface surface area increases with long-term potentiation in the hippocampal dentate gyrusQ30462747
Learning and generalization in schizophrenia: effects of disease and antipsychotic drug treatmentQ33622586
GABA-ergic neurons and the neurobiology of schizophrenia and other psychosesQ33662308
Evidence for altered trisynaptic circuitry in schizophrenic hippocampusQ33725843
Lower number of cerebellar Purkinje neurons in psychosis is associated with reduced reelin expression.Q33732865
Role for Reelin in neurotransmitter release.Q33821827
Gender effect on Purkinje cell loss in the cerebellum of the heterozygous reeler mouseQ33907853
New neurochemical markers for psychosis: a working hypothesis of their operationQ34074201
Secreted Reelin molecules form homodimers.Q34140685
REELIN and schizophrenia: a disease at the interface of the genome and the epigenomeQ34302284
The reeler gene-associated antigen on Cajal-Retzius neurons is a crucial molecule for laminar organization of cortical neurons.Q34310467
Hypermethylation of the reelin (RELN) promoter in the brain of schizophrenic patients: a preliminary reportQ34395443
???Q56094599
Reelin is a secreted glycoprotein recognized by the CR-50 monoclonal antibody.Q34412746
The heterozygote reeler mouse as a model for the development of a new generation of antipsychoticsQ34489892
Molecular genetics and animal models in autistic disorderQ34517515
Reelin down-regulation in mice and psychosis endophenotypesQ34537189
Down-regulation of dendritic spine and glutamic acid decarboxylase 67 expressions in the reelin haploinsufficient heterozygous reeler mouseQ34742022
Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidenceQ34894451
From trans-methylation to cytosine methylation: evolution of the methylation hypothesis of schizophreniaQ34977902
The human reelin gene: transcription factors (+), repressors (-) and the methylation switch (+/-) in schizophrenia.Q36436017
Molecular and cellular mechanisms of altered GAD1/GAD67 expression in schizophrenia and related disordersQ36499391
Anatomical and physiological plasticity of dendritic spinesQ36728838
Gene-environment interaction during early development in the heterozygous reeler mouse: clues for modelling of major neurobehavioral syndromes.Q37290439
Startle response models of sensorimotor gating and habituation deficits in schizophreniaQ38037660
Altered hippocampus synaptic function in selenoprotein P deficient miceQ38470321
Differential reelin-induced enhancement of NMDA and AMPA receptor activity in the adult hippocampus.Q40196818
Polymorphic GGC repeat differentially regulates human reelin gene expression levelsQ40294194
Sensory gating and inhibitory function in late-life schizophreniaQ40812146
Symptom correlates of prepulse inhibition deficits in male schizophrenic patientsQ40817813
Startle habituation and sensorimotor gating in schizophrenia and related animal modelsQ41443315
Impulsivity-anxiety-related behavior and profiles of morphine-induced analgesia in heterozygous reeler mice.Q42505676
Combinatorial morphogenesis of dendritic spines and filopodia by SPAR and alpha-actinin2.Q42737897
Perseverative responding and neuroanatomical alterations in adult heterozygous reeler mice are mitigated by neonatal estrogen administration.Q43069354
Preferential alterations in the mesolimbic dopamine pathway of heterozygous reeler mice: an emerging animal-based model of schizophrenia.Q43975385
Tyrosine phosphorylation of Disabled-1 is essential for Reelin-stimulated activation of Akt and Src family kinasesQ44617813
Behavioral phenotype of the reeler mutant mouse: effects of RELN gene dosage and social isolationQ44692793
Reelin depletion in the entorhinal cortex of human amyloid precursor protein transgenic mice and humans with Alzheimer's disease.Q46854865
Cognitive disruption and altered hippocampus synaptic function in Reelin haploinsufficient miceQ46866779
The phenotypic characteristics of heterozygous reeler mouseQ48190249
The reeler mouse as a model of brain developmentQ48350261
Impairment on the hippocampal-dependent virtual Morris water task in schizophreniaQ48470283
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectsynaptic plasticityQ1551556
heterozygosityQ124059385
P304page(s)386-395
P577publication date2012-10-26
P1433published inJournal of PsychopharmacologyQ6295819
P1476titleReelin supplementation recovers sensorimotor gating, synaptic plasticity and associative learning deficits in the heterozygous reeler mouse
P478volume27

Reverse relations

cites work (P2860)
Q26738423Canonical and Non-canonical Reelin Signaling
Q34095829Characterization of hippocampal Cajal-Retzius cells during development in a mouse model of Alzheimer's disease (Tg2576)
Q33556306Cleavage within Reelin repeat 3 regulates the duration and range of the signaling activity of Reelin protein
Q26752594Epigenetic RELN Dysfunction in Schizophrenia and Related Neuropsychiatric Disorders
Q38264895Extracellular matrix control of dendritic spine and synapse structure and plasticity in adulthood
Q92571861Fast-acting antidepressant-like effects of Reelin evaluated in the repeated-corticosterone chronic stress paradigm
Q38578808From mice to men: lessons from mutant ataxic mice
Q89743437Generation and analysis of novel Reln-deleted mouse model corresponding to exonic Reln deletion in schizophrenia
Q48034984Hypervulnerability of the adolescent prefrontal cortex to nutritional stress via reelin deficiency.
Q37500060Identifying essential cell types and circuits in autism spectrum disorders.
Q35754509Increased Blood-Reelin-Levels in First Episode Schizophrenia
Q38165200Is the mTOR-signalling cascade disrupted in Schizophrenia?
Q27334994Mice that lack the C-terminal region of Reelin exhibit behavioral abnormalities related to neuropsychiatric disorders.
Q89963801Modulation of Hippocampal Gamma Oscillations by Dopamine in Heterozygous Reeler Mice in vitro
Q34557404More than cholesterol transporters: lipoprotein receptors in CNS function and neurodegeneration
Q50346016Neuronal migration disorders: Focus on the cytoskeleton and epilepsy.
Q26750436RELN Mutations in Autism Spectrum Disorder
Q42102539Reelin Exerts Structural, Biochemical and Transcriptional Regulation Over Presynaptic and Postsynaptic Elements in the Adult Hippocampus
Q26749956Reelin Proteolysis Affects Signaling Related to Normal Synapse Function and Neurodegeneration
Q30823270Reelin Regulates the Maturation of Dendritic Spines, Synaptogenesis and Glial Ensheathment of Newborn Granule Cells.
Q28072540Reelin and Neuropsychiatric Disorders
Q39875271Reelin in Alzheimer's Disease, Increased Levels but Impaired Signaling: When More is Less.
Q59047757Reelin in the Years: Controlling Neuronal Migration and Maturation in the Mammalian Brain
Q36299546Reelin protects against amyloid β toxicity in vivo
Q36364620Reelin supplementation recovers synaptic plasticity and cognitive deficits in a mouse model for Angelman syndrome
Q26768609Reelin-Related Disturbances in Depression: Implications for Translational Studies
Q37195872Schizophrenia patient-derived olfactory neurosphere-derived cells do not respond to extracellular reelin
Q48221943Secreted Metalloproteinase ADAMTS-3 Inactivates Reelin.
Q93112033Spermidine/spermine-N1-acetyltransferase ablation impacts tauopathy-induced polyamine stress response
Q48283957Subacute ibuprofen treatment rescues the synaptic and cognitive deficits in advanced-aged mice
Q91726833The Reeler Mouse: A Translational Model of Human Neurological Conditions, or Simply a Good Tool for Better Understanding Neurodevelopment?
Q89819985Two Novel Loci of RELN Associated With Antipsychotics Response in Chinese Han Population

Search more.