Induction of neurite outgrowth by v-src mimics critical aspects of nerve growth factor-induced differentiation

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Induction of neurite outgrowth by v-src mimics critical aspects of nerve growth factor-induced differentiation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.11.9.4739
P932PMC publication ID361372
P698PubMed publication ID1875950

P2093author name stringJ S Brugge
S M Thomas
B E Meyer
R C Armstrong
M Hayes
G D'Arcangelo
S Halegoua
A Zilberstein
P2860cites workProtein measurement with the Folin phenol reagentQ20900776
Expression and structure of the human NGF receptorQ24295226
Induction of the proto-oncogene fos by nerve growth factorQ37553567
Dissecting the mode of action of a neuronal growth factorQ37717396
Calcium-mobilizing receptors, polyphosphoinositides, and the generation of second messengers.Q39505415
PDGF stimulation of inositol phospholipid hydrolysis requires PLC-gamma 1 phosphorylation on tyrosine residues 783 and 1254.Q41684625
High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptorQ41687095
Association between the PDGF receptor and members of the src family of tyrosine kinasesQ41725198
Retinoic acid induces down-regulation of several growth factors and proto-oncogenes in a human embryonal cancer cell lineQ41738941
Calcium-dependent nerve growth factor-stimulated hydrolysis of phosphoinositides in PC12 cellsQ42509666
p1B15: a cDNA clone of the rat mRNA encoding cyclophilinQ42656764
Nerve growth factor stimulates phosphorylation of phospholipase C-gamma in PC12 cellsQ44100855
src kinase catalyzes the phosphorylation and activation of the insulin receptor kinase.Q44655466
Increase of the Catalytic Activity of Phospholipase C-γ1 by Tyrosine PhosphorylationQ44763188
Analysis of the catalytic domain of phosphotransferase activity of two avian sarcoma virus-transforming proteinsQ45796833
Polyphosphoinositide metabolism is rapidly stimulated by activation of a temperature-sensitive mutant of Rous sarcoma virus in rat fibroblasts.Q45841911
Role of protein tyrosine phosphorylation in the NGF responseQ46455649
Differentiation of PC12 cells with v-src: comparison with nerve growth factor.Q52085152
Gene transfer and molecular cloning of the human NGF receptor.Q53537335
Activated N-ras gene induces neuronal differentiation of PC12 rat pheochromocytoma cells.Q54421458
Differentiation of PC12 phaeochromocytoma cells induced by v-src oncogeneQ59073572
Sarcoma viruses carrying ras oncogenes induce differentiation-associated properties in a neuronal cell lineQ59094087
Inhibition of growth factor-induced differentiation of PC12 cells by microinjection of antibody to ras p21Q59094093
Cell-substratum adhesion of neurite growth cones, and its role in neurite elongationQ66959875
Characterization and isolation of proteolytically modified nerve growth factorQ67877030
K-252a: a specific inhibitor of the action of nerve growth factor on PC 12 cellsQ68259333
Magnesium-dependent attachment and neurite outgrowth by PC12 cells on collagen and laminin substrataQ69022212
EGF induces tyrosine phosphorylation of phospholipase C-II: a potential mechanism for EGF receptor signalingQ69078300
The induction of a neural-specific gene, SCG10, by nerve growth factor in PC12 cells is transcriptional, protein synthesis dependent, and glucocorticoid inhibitableQ69829027
Nerve growth factor and other agents mediate phosphorylation and activation of tyrosine hydroxylase. A convergence of multiple kinase activitiesQ69866745
Nerve growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PC12 cellsQ69874602
Microinjection of the ras oncogene protein into PC12 cells induces morphological differentiationQ70104566
Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factorQ24561804
Gene transfer and molecular cloning of the rat nerve growth factor receptorQ28288106
The trk proto-oncogene encodes a receptor for nerve growth factorQ28609788
The trk Proto-Oncogene Product: a Signal Transducing Receptor for Nerve Growth FactorQ28609789
Tyrosine kinase activity is essential for the association of phospholipase C-gamma with the epidermal growth factor receptorQ28609951
Phospholipase C-gamma is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitroQ28625928
Improved retroviral vectors for gene transfer and expressionQ29614384
Phosphorylation and activation of epidermal growth factor receptors in cells transformed by the src oncogeneQ30441810
Constitutive phosphorylation of the receptor for insulinlike growth factor I in cells transformed by the src oncogeneQ30450353
Monoclonal antibodies to Rous sarcoma virus pp60src react with enzymatically active cellular pp60src of avian and mammalian originQ30452279
Nerve growth factor induces protein-tyrosine phosphorylationQ33647811
Antibody to phosphatidylinositol 4,5-bisphosphate inhibits oncogene-induced mitogenesisQ33679375
Epidermal growth factor stimulates tyrosine phosphorylation of phospholipase C-II independently of receptor internalization and extracellular calciumQ33840438
A method for isolation of intact, translationally active ribonucleic acid.Q34054939
Steps in the neoplastic transformation of hamster embryo cells by polyoma virusQ34383690
Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF.Q34576586
K-252a, a potent protein kinase inhibitor, blocks nerve growth factor-induced neurite outgrowth and changes in the phosphorylation of proteins in PC12h cellsQ34681764
Regulation of the differentiation of PC12 pheochromocytoma cellsQ35032923
Alteration of cellular adhesion by nerve growth factorQ35053463
Nerve growth factor rapidly induces c-fos mRNA in PC12 rat pheochromocytoma cellsQ35614658
Nerve growth factor action is mediated by cyclic AMP- and Ca+2/phospholipid-dependent protein kinasesQ36215329
Interactions of a neuronal cell line (PC12) with laminin, collagen IV, and fibronectin: identification of integrin-related glycoproteins involved in attachment and process outgrowthQ36217781
Dissociation of inositol trisphosphate from diacylglycerol production in Rous sarcoma virus-transformed fibroblastsQ36220044
Transforming protein of avian sarcoma virus UR2 is associated with phosphatidylinositol kinase activity: possible role in tumorigenesisQ36259155
Evidence that the Rous sarcoma virus transforming gene product phosphorylates phosphatidylinositol and diacylglycerolQ36266572
A nerve growth factor-induced gene encodes a possible transcriptional regulatory factor.Q36472744
Effect of a dominant inhibitory Ha-ras mutation on neuronal differentiation of PC12 cellsQ36728456
Platelet-derived growth factor induces multisite phosphorylation of pp60c-src and increases its protein-tyrosine kinase activity.Q36793338
Genetic analysis of p60v-src domains involved in the induction of different cell transformation parametersQ36869296
Genetic lesions involved in temperature sensitivity of the src gene products of four Rous sarcoma virus mutantsQ36869418
Analysis of p60v-src mutants carrying lesions involved in temperature sensitivityQ36884430
Phosphatidylinositol kinase activities in normal and Rous sarcoma virus-transformed cellsQ36951652
Barium modulates c-fos expression and post-translational modificationQ37407154
The product of the protooncogene c-src is modified during the cellular response to platelet-derived growth factorQ37537225
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectneuriteQ1534415
P304page(s)4739-4750
P577publication date1991-09-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleInduction of neurite outgrowth by v-src mimics critical aspects of nerve growth factor-induced differentiation
P478volume11

Reverse relations

cites work (P2860)
Q36684518A branched signaling pathway for nerve growth factor is revealed by Src-, Ras-, and Raf-mediated gene inductions
Q40533238A novel lymphocyte signaling defect: trk A mutation in the syndrome of congenital insensitivity to pain and anhidrosis (CIPA).
Q36561816Activation of codependent transcription factors is required for transcriptional induction of the vgf gene by nerve growth factor and Ras.
Q40914124Adenosine A(2A) receptor mRNA regulation by nerve growth factor is TrkA-, Src-, and Ras-dependent via extracellular regulated kinase and stress-activated protein kinase/c-Jun NH(2)-terminal kinase
Q40423482CSK negatively regulates nerve growth factor induced neural differentiation and augments AKT kinase activity
Q30176318Distinctive regulation of v-Src-associated phosphatidylinositol 3-kinase during PC12 cell differentiation
Q72578612Enhanced expression of Ca2+ channels by nerve growth factor and the v-src oncogene in rat phaeochromocytoma cells
Q24613828Expression of the v-crk oncogene product in PC12 cells results in rapid differentiation by both nerve growth factor- and epidermal growth factor-dependent pathways
Q41452653Fibroblast growth factor-induced increases in calcium currents in the PC12 pheochromocytoma cell line are tyrosine phosphorylation dependent
Q33602323Ion channels as physiological effectors for growth factor receptor and Ras/ERK signaling pathways.
Q44925761K252a-potentiation of EGF-induced neurite outgrowth from PC12 cells is not mimicked or blocked by other protein kinase activators or inhibitors
Q37333802LRP1 assembles unique co-receptor systems to initiate cell signaling in response to tissue-type plasminogen activator and myelin-associated glycoprotein.
Q33964065Mapping of atypical protein kinase C within the nerve growth factor signaling cascade: relationship to differentiation and survival of PC12 cells
Q36552522Mitogen-activated protein kinase activation is insufficient for growth factor receptor-mediated PC12 cell differentiation
Q28244751Nerve growth factor regulates the subcellular localization of the nerve growth factor-inducible protein PC4 in PC12 cells
Q36232516Neuronal growth factor regulation of two different sodium channel types through distinct signal transduction pathways.
Q72691247Oncogenically activated or ligand-stimulated neu kinase stimulates neurite outgrowth in PC12 cells
Q35229328Protein tyrosine kinases in nervous system development
Q24564404Receptor protein tyrosine phosphatase alpha activates pp60c-src and is involved in neuronal differentiation
Q36678095SNT, a Differentiation-Specific Target of Neurotrophic Factor-Induced Tyrosine Kinase Activity in Neurons and PC12 Cells
Q36530489Signal transduction by nerve growth factor and fibroblast growth factor in PC12 cells requires a sequence of src and ras actions
Q73704050Simultaneous suppression of cdc2 and cdk2 activities induces neuronal differentiation of PC12 cells
Q71343407Src, ras, and rac mediate the migratory response elicited by NGF and PMA in PC12 cells
Q41516695The Wnt-1 proto-oncogene induces changes in morphology, gene expression, and growth factor responsiveness in PC12 cells
Q40485520The cell cycle and c-Src
Q36332163The cytoplasmic raf oncogene induces a neuronal phenotype in PC12 cells: a potential role for cellular raf kinases in neuronal growth factor signal transduction
Q36255177The neurite-initiating effect of microbial extracellular glycolipids in PC12 cells
Q32061981c-Src is required for glial cell line-derived neurotrophic factor (GDNF) family ligand-mediated neuronal survival via a phosphatidylinositol-3 kinase (PI-3K)-dependent pathway.
Q41634356ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK

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