scholarly article | Q13442814 |
P2093 | author name string | S J Parsons | |
J T Parsons | |||
L K Wilson | |||
D K Luttrell | |||
P2860 | cites work | A novel viral oncogene with structural similarity to phospholipase C | Q28307371 |
Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter | Q29614259 | ||
Activation of the oncogenic potential of the avian cellular src protein by specific structural alteration of the carboxy terminus. | Q30448511 | ||
Amino Acid Alterations Within a Highly Conserved Region of the Rous Sarcoma Virus src Gene Product pp60src Inactivate Tyrosine Protein Kinase Activity | Q30449986 | ||
Augmented mitogenic responsiveness to epidermal growth factor in murine fibroblasts that overexpress pp60c-src | Q30450435 | ||
Reduced tyrosine kinase specific activity is associated with hypophosphorylation of pp60c-src in cells infected with avian erythroblastosis virus | Q30450893 | ||
Deletions and insertions within an amino-terminal domain of pp60v-src inactivate transformation and modulate membrane stability | Q30452209 | ||
Localization of conserved and nonconserved epitopes within the Rous sarcoma virus-encoded src protein. | Q30452242 | ||
Activation of pp60c-src tyrosine kinase specific activity in tumor-derived Syrian hamster embryo cells. | Q30457411 | ||
Identification of an amino terminal domain required for the transforming activity of the Rous sarcoma virus src protein | Q30463102 | ||
Mutations around the NG59 lesion indicate an active association of polyoma virus middle-T antigen with pp60c-src is required for cell transformation | Q33879388 | ||
Activation of the pp60c-src kinase by middle T antigen binding or by dephosphorylation | Q33931404 | ||
DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells | Q34048204 | ||
Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation | Q34166097 | ||
Structure and sequence of the cellular gene homologous to the RSV src gene and the mechanism for generating the transforming virus | Q34254297 | ||
Blood platelets express high levels of the pp60c-src-specific tyrosine kinase activity | Q35589675 | ||
Activation of the transforming potential of p60c-src by a single amino acid change | Q35610574 | ||
The first seven amino acids encoded by the v-src oncogene act as a myristylation signal: lysine 7 is a critical determinant | Q36790275 | ||
Platelet-derived growth factor induces multisite phosphorylation of pp60c-src and increases its protein-tyrosine kinase activity. | Q36793338 | ||
Platelet tyrosine-specific protein phosphorylation is regulated by thrombin | Q36844443 | ||
The absence of myristic acid decreases membrane binding of p60src but does not affect tyrosine protein kinase activity | Q36862547 | ||
Overexpressed pp60c-src can induce focus formation without complete transformation of NIH 3T3 cells | Q36888885 | ||
N-terminal deletions in Rous sarcoma virus p60src: effects on tyrosine kinase and biological activities and on recombination in tissue culture with the cellular src gene | Q36895142 | ||
Myristic acid, a rare fatty acid, is the lipid attached to the transforming protein of Rous sarcoma virus and its cellular homolog | Q36903643 | ||
Isolation of monoclonal antibodies that recognize the transforming proteins of avian sarcoma viruses | Q36909345 | ||
Tyrosine phosphorylation of specific proteins after mitogen stimulation of chicken embryo fibroblasts | Q36937100 | ||
Mutation of NH2-terminal glycine of p60src prevents both myristoylation and morphological transformation | Q37523303 | ||
The product of the protooncogene c-src is modified during the cellular response to platelet-derived growth factor | Q37537225 | ||
Subcellular localization of pp60src in RSV-transformed cells | Q40140350 | ||
Reconstitution of the Rous sarcoma virus transforming protein pp60v-src into phospholipid vesicles | Q40649687 | ||
Amino acid substitutions sufficient to convert the nontransforming p60c-src protein to a transforming protein | Q40667798 | ||
Altered sites of tyrosine phosphorylation in pp60c-src associated with polyomavirus middle tumor antigen | Q40669975 | ||
An N-terminal peptide from p60src can direct myristylation and plasma membrane localization when fused to heterologous proteins | Q41488933 | ||
Activation of the pp60c-src kinase during differentiation of monomyelocytic cells in vitro | Q42273784 | ||
Altered phosphorylation and activation of pp60c-src during fibroblast mitosis | Q42804505 | ||
The cellular src gene product regulates junctional cell-to-cell communication | Q42805146 | ||
Cell transformation by pp60c-src mutated in the carboxy-terminal regulatory domain | Q42808327 | ||
Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src | Q44049774 | ||
Oncogene-mediated multistep transformation of C3H10T1/2 cells | Q44806159 | ||
pp60c-src is a substrate for phosphorylation when cells are stimulated to enter cycle | Q44966106 | ||
Analysis of the catalytic domain of phosphotransferase activity of two avian sarcoma virus-transforming proteins | Q45796833 | ||
Polyoma virus transforming protein associates with the product of the c-src cellular gene | Q45798405 | ||
Enhancement of polyoma virus middle T antigen tyrosine phosphorylation by epidermal growth factor | Q45804706 | ||
The nucleotide sequence and the tissue-specific expression of Drosophila c-src | Q47072139 | ||
Sequence similarity of phospholipase C with the non-catalytic region of src. | Q48099424 | ||
pp60c-src is developmentally regulated in the neural retina | Q60654496 | ||
Fetal Bovine Serum: A Multivariate Standard | Q66961587 | ||
p60c-src activity detected in the chromaffin granule membrane | Q68860356 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | overexpression | Q61643320 |
P304 | page(s) | 1536-1544 | |
P577 | publication date | 1989-04-01 | |
P1433 | published in | Molecular and Cellular Biology | Q3319478 |
P1476 | title | pp60c-src tyrosine kinase, myristylation, and modulatory domains are required for enhanced mitogenic responsiveness to epidermal growth factor seen in cells overexpressing c-src | |
P478 | volume | 9 |
Q30450210 | A protein that is highly related to GTPase-activating protein-associated p62 complexes with phospholipase C gamma |
Q30468973 | Activation of Fyn tyrosine kinase upon secretagogue stimulation of bovine chromaffin cells |
Q58134938 | Activation of Src in human breast tumor cell lines: elevated levels of phosphotyrosine phosphatase activity that preferentially recognizes the Src carboxy terminal negative regulatory tyrosine 530 |
Q53396671 | Activation of c-Src gene product in hepatocellular carcinoma is highly correlated with the indices of early stage phenotype. |
Q44582560 | Agonist-specific transactivation of phosphoinositide 3-kinase signaling pathway mediated by the dopamine D2 receptor |
Q28298083 | Brk, a breast tumor-derived non-receptor protein-tyrosine kinase, sensitizes mammary epithelial cells to epidermal growth factor |
Q30175350 | Cas mediates transcriptional activation of the serum response element by Src. |
Q38109021 | Cellular functions regulated by phosphorylation of EGFR on Tyr845. |
Q30472067 | Characterization of human epidermal growth factor receptor and c-Src interactions in human breast tumor cells |
Q30454300 | Complex formation with focal adhesion kinase: A mechanism to regulate activity and subcellular localization of Src kinases |
Q43649346 | Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells |
Q30450353 | Constitutive phosphorylation of the receptor for insulinlike growth factor I in cells transformed by the src oncogene |
Q28236497 | Csk-binding protein (Cbp) negatively regulates epidermal growth factor-induced cell transformation by controlling Src activation |
Q40021748 | DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases. |
Q30175829 | Dissection of the molecular basis of pp60(v-src) induced gating of connexin 43 gap junction channels |
Q40342689 | Elevated Src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells. |
Q28139023 | Enhancement of tyrosyl phosphorylation and protein expression of eps8 by v-Src |
Q62604103 | Epidermal Growth Factor-induced DNA Synthesis |
Q41436659 | Functional interaction between the epidermal growth factor receptor and c‐Src kinase activity |
Q40631092 | Ganglioside GM3 blocks the activation of epidermal growth factor receptor induced by integrin at specific tyrosine sites |
Q30463936 | Identification of the in vitro phosphorylation sites on Gs alpha mediated by pp60c-src |
Q30442141 | Induction of apoptosis after expression of PYK2, a tyrosine kinase structurally related to focal adhesion kinase |
Q40962053 | Integrin-mediated migration of murine B82L fibroblasts is dependent on the expression of an intact epidermal growth factor receptor |
Q41326657 | Interaction between lck and syk family tyrosine kinases in Fc gamma receptor-initiated activation of natural killer cells |
Q30194582 | Involvement of pp60c-src with two major signaling pathways in human breast cancer |
Q33897202 | Kinase inhibitors in cancer therapy: a look ahead |
Q30454480 | Mechanism of biological synergy between cellular Src and epidermal growth factor receptor |
Q34224865 | Mechanisms of action of flavopiridol |
Q36675443 | Myristylation is required for Tyr-527 dephosphorylation and activation of pp60c-src in mitosis |
Q28323490 | Overexpression of c-src enhances beta-adrenergic-induced cAMP accumulation |
Q41075249 | Overexpression of cellular Src in fibroblasts enhances endocytic internalization of epidermal growth factor receptor |
Q41605774 | Overexpression of pp60c-src is associated with altered regulation of adenylyl cyclase |
Q30441810 | Phosphorylation and activation of epidermal growth factor receptors in cells transformed by the src oncogene |
Q30434083 | Phosphorylation of Y845 on the epidermal growth factor receptor mediates binding to the mitochondrial protein cytochrome c oxidase subunit II. |
Q30453620 | Phosphotyrosine (p-Tyr)-dependent and -independent mechanisms of p190 RhoGAP-p120 RasGAP interaction: Tyr 1105 of p190, a substrate for c-Src, is the sole p-Tyr mediator of complex formation |
Q45204444 | Plasminogen activator inhibitor type-1 gene expression and induced migration in TGF-beta1-stimulated smooth muscle cells is pp60(c-src)/MEK-dependent |
Q30453944 | Potentiation of epidermal growth factor receptor-mediated oncogenesis by c-Src: implications for the etiology of multiple human cancers |
Q33631172 | Protein myristoylation in health and disease |
Q28243770 | Regulation of SRC family kinases in human cancers |
Q30176895 | Requirement for c-Src catalytic activity and the SH3 domain in platelet-derived growth factor BB and epidermal growth factor mitogenic signaling |
Q46372936 | Requirement of inducible nitric-oxide synthase in lipopolysaccharide-mediated Src induction and macrophage migration |
Q30310214 | STAT5b, a Mediator of Synergism between c-Src and the Epidermal Growth Factor Receptor |
Q46407291 | Src activation triggers capacitation and acrosome reaction but not motility in human spermatozoa |
Q30307291 | Src family kinases and HER2 interactions in human breast cancer cell growth and survival |
Q22253382 | Src family kinases negatively regulate platelet-derived growth factor alpha receptor-dependent signaling and disease progression |
Q30470153 | Src family protein tyrosine kinases: cooperating with growth factor and adhesion signaling pathways |
Q33959239 | Src in cancer: deregulation and consequences for cell behaviour |
Q34481586 | Src inhibitors: genomics to therapeutics |
Q34806104 | Src promotes destruction of c-Cbl: implications for oncogenic synergy between Src and growth factor receptors |
Q30360087 | Src-dependent tyrosine phosphorylation of non-muscle myosin heavy chain-IIA restricts Listeria monocytogenes cellular infection |
Q41846085 | Targeting SRC and epidermal growth factor receptor in colorectal cancer: rationale and progress into the clinic. |
Q37167029 | Targeting Src in breast cancer |
Q30164215 | The C terminus of c-Src inhibits breast tumor cell growth by a kinase-independent mechanism |
Q37066428 | The RON receptor tyrosine kinase promotes MSP-independent cell spreading and survival in breast epithelial cells |
Q30450277 | The Sites of Phosphorylation by Protein Kinase C and an Intact SH2 Domain Are Required for the Enhanced Response to β-Adrenergic Agonists in Cells Overexpressing c-src |
Q30176898 | The Src SH3 domain is required for DNA synthesis induced by platelet-derived growth factor and epidermal growth factor |
Q42378470 | The activation of SRC family kinases and focal adhesion kinase with the loss of the amplified, mutated EGFR gene contributes to the resistance to afatinib, erlotinib and osimertinib in human lung cancer cells |
Q28210439 | The epidermal growth factor receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and beta-catenin |
Q26853018 | The molecular rationale of Src inhibition in colorectal carcinomas |
Q44002704 | The presence of a single tyrosine residue at the carboxyl domain of vascular endothelial growth factor receptor-2/FLK-1 regulates its autophosphorylation and activation of signaling molecules |
Q30438058 | Transactivating agonists of the EGF receptor require Tyr 845 phosphorylation for induction of DNA synthesis |
Q30441879 | Transformation by pp60src or stimulation of cells with epidermal growth factor induces the stable association of tyrosine-phosphorylated cellular proteins with GTPase-activating protein |
Q24803054 | Tyrosine kinase signalling in breast cancer: epidermal growth factor receptor and c-Src interactions in breast cancer |
Q24648808 | Tyrosine phosphorylation of selected secretory carrier membrane proteins, SCAMP1 and SCAMP3, and association with the EGF receptor |
Q30442121 | Tyrosine phosphorylation of three cellular proteins correlates with transformation of rat 1 cells by pp60src |
Q30448769 | c-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGF |
Q30442226 | c-Src regulates the simultaneous rearrangement of actin cytoskeleton, p190RhoGAP, and p120RasGAP following epidermal growth factor stimulation |
Q40090625 | c-Src trafficking and co-localization with the EGF receptor promotes EGF ligand-independent EGF receptor activation and signaling |
Q30303932 | c-Src, receptor tyrosine kinases, and human cancer |
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