Fragile X mental retardation protein is required for rapid experience-dependent regulation of the potassium channel Kv3.1b

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Fragile X mental retardation protein is required for rapid experience-dependent regulation of the potassium channel Kv3.1b is …
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scholarly articleQ13442814

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P356DOI10.1523/JNEUROSCI.1125-10.2010
P932PMC publication ID3485078
P698PubMed publication ID20685971

P2093author name stringLeonard K Kaczmarek
Daniel B Polley
Jack Kronengold
Maile R Brown
John G Strumbos
P2860cites workFMR1 Protein: Conserved RNP Family Domains and Selective RNA BindingQ24311412
Fragile X syndrome: loss of local mRNA regulation alters synaptic development and functionQ24608468
Evidence that fragile X mental retardation protein is a negative regulator of translationQ28117211
Properties and expression of Kv3 channels in cerebellar Purkinje cellsQ48430589
Envelope coding in the lateral superior olive. III. Comparison with afferent pathwaysQ48531193
The potassium channel subunit KV3.1b is localized to somatic and axonal membranes of specific populations of CNS neuronsQ49049978
Topographic organization in the auditory brainstem of juvenile mice is disrupted in congenital deafness.Q50468437
Direct patch recording from identified presynaptic terminals mediating glutamatergic EPSCs in the rat CNS, in vitro.Q51625037
Electrodermal responses to sensory stimuli in individuals with fragile X syndrome: a preliminary report.Q51985541
Speech disturbances (cluttering) in mildly impaired males with the Martin-Bell/fragile X syndrome.Q52142657
Pre- and postsynaptic glutamate receptors at a giant excitatory synapse in rat auditory brainstem slicesQ70917657
The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapsesQ28208647
Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndromeQ28302665
Electrophysiological and pharmacological characterization of a mammalian Shaw channel expressed in NIH 3T3 fibroblastsQ28567774
Localization of two high-threshold potassium channel subunits in the rat central auditory systemQ28577619
Specific and rapid effects of acoustic stimulation on the tonotopic distribution of Kv3.1b potassium channels in the adult ratQ28581190
Expression of the mRNAs for the Kv3.1 potassium channel gene in the adult and developing rat brainQ28583610
The fragile X mental retardation protein inhibits translation via interacting with mRNAQ28588486
Fragile X mental retardation protein targets G quartet mRNAs important for neuronal functionQ29616372
Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndromeQ29616495
The medial nucleus of the trapezoid body in the gerbil is more than a relay: comparison of pre- and postsynaptic activityQ30473467
Encoding of temporal features of auditory stimuli in the medial nucleus of the trapezoid body and superior paraolivary nucleus of the rat.Q30496668
On the cellular and network bases of epileptic seizures.Q31963797
Synaptic mechanisms for coding timing in auditory neuronsQ33547248
Kv3 channels: voltage-gated K+ channels designed for high-frequency repetitive firingQ34086958
Fast delayed rectifier potassium current is required for circadian neural activityQ34595087
Activation of Kv3.1 channels in neuronal spine-like structures may induce local potassium ion depletionQ35895029
Regulation of the timing of MNTB neurons by short-term and long-term modulation of potassium channelsQ36218700
On BC1 RNA and the fragile X mental retardation protein.Q36393017
Fragile X-related proteins regulate mammalian circadian behavioral rhythmsQ36744675
The neural basis of auditory temporal discrimination in girls with fragile X syndromeQ37409328
The fragile X protein controls microtubule-associated protein 1B translation and microtubule stability in brain neuron development.Q37589711
Kv3.4 subunits enhance the repolarizing efficiency of Kv3.1 channels in fast-spiking neuronsQ39750760
Distinct roles of Kv1 and Kv3 potassium channels at the calyx of Held presynaptic terminal.Q39750979
Fragile X mental retardation protein is associated with translating polyribosomes in neuronal cells.Q40524276
Differential subcellular localization of the two alternatively spliced isoforms of the Kv3.1 potassium channel subunit in brain.Q40721414
Contribution of the Kv3.1 potassium channel to high-frequency firing in mouse auditory neuronesQ41034714
Encoding of timing in the brain stem auditory nuclei of vertebratesQ41656227
Fragile X mice develop sensory hyperreactivity to auditory stimuliQ43574481
Modulation of the kv3.1b potassium channel isoform adjusts the fidelity of the firing pattern of auditory neurons.Q44323425
The medial nucleus of the trapezoid body: comparative physiology.Q45374692
Systematic variation of potassium current amplitudes across the tonotopic axis of the rat medial nucleus of the trapezoid bodyQ46635126
Acoustic environment determines phosphorylation state of the Kv3.1 potassium channel in auditory neuronsQ46681614
Fine-tuning an auditory synapse for speed and fidelity: developmental changes in presynaptic waveform, EPSC kinetics, and synaptic plasticity.Q46689899
Synaptic mitochondria are more susceptible to Ca2+overload than nonsynaptic mitochondriaQ46975941
Distribution of HCN1 and HCN2 in rat auditory brainstem nucleiQ47221332
High-frequency firing helps replenish the readily releasable pool of synaptic vesiclesQ47741527
Heterologous expression of the Kv3.1 potassium channel eliminates spike broadening and the induction of a depolarizing afterpotential in the peptidergic bag cell neurons.Q47907181
When, where, and how much? Expression of the Kv3.1 potassium channel in high-frequency firing neuronsQ47907391
Loss of Kv3.1 tonotopicity and alterations in cAMP response element-binding protein signaling in central auditory neurons of hearing impaired mice.Q48033911
Epilepsy and EEG findings in males with fragile X syndrome.Q48135370
Slack and Slick K(Na) channels regulate the accuracy of timing of auditory neuronsQ48250784
Subcellular localization of the voltage-dependent potassium channel Kv3.1b in postnatal and adult rat medial nucleus of the trapezoid body.Q48317618
Principal cells of the rat medial nucleus of the trapezoid body: an intracellular in vivo study of their physiology and morphology.Q48381661
P4510describes a project that usesImageJQ1659584
P433issue31
P407language of work or nameEnglishQ1860
P304page(s)10263-10271
P577publication date2010-08-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleFragile X mental retardation protein is required for rapid experience-dependent regulation of the potassium channel Kv3.1b
P478volume30

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cites work (P2860)
Q30841903A resting EEG study of neocortical hyperexcitability and altered functional connectivity in fragile X syndrome
Q95930009ATP synthase c-subunit ring as the channel of mitochondrial permeability transition: Regulator of metabolism in development and degeneration
Q48244382Abnormal presynaptic short-term plasticity and information processing in a mouse model of fragile X syndrome
Q35514214Altered neocortical rhythmic activity states in Fmr1 KO mice are due to enhanced mGluR5 signaling and involve changes in excitatory circuitry
Q30442883Auditory processing in fragile x syndrome
Q34785622Bidirectional control of BK channel open probability by CAMKII and PKC in medial vestibular nucleus neurons
Q30460772Bidirectional regulation of dendritic voltage-gated potassium channels by the fragile X mental retardation protein
Q92920694Cataloguing and Selection of mRNAs Localized to Dendrites in Neurons and Regulated by RNA-Binding Proteins in RNA Granules
Q42054553Cell-Type Specific Channelopathies in the Prefrontal Cortex of the fmr1-/y Mouse Model of Fragile X Syndrome.
Q90910835Cellular and synaptic phenotypes lead to disrupted information processing in Fmr1-KO mouse layer 4 barrel cortex
Q41428079Cellular distribution of the fragile X mental retardation protein in the mouse brain
Q27022703Channelopathies and dendritic dysfunction in fragile X syndrome
Q92739252Characterization of Auditory and Binaural Spatial Hearing in a Fragile X Syndrome Mouse Model
Q30411291Degraded speech sound processing in a rat model of fragile X syndrome
Q30418164Deletion of Fmr1 alters function and synaptic inputs in the auditory brainstem.
Q48209105Disrupted-in-schizophrenia 1 regulates transport of ITPR1 mRNA for synaptic plasticity
Q92213850Disruption of GpI mGluR-Dependent Cav2.3 Translation in a Mouse Model of Fragile X Syndrome
Q95656749Dynamics of the Fragile X Mental Retardation Protein Correlates with Cellular and Synaptic Properties in Primary Auditory Neurons following Afferent Deprivation
Q26782616Dysregulation and restoration of translational homeostasis in fragile X syndrome
Q47678007Enhanced Excitatory Connectivity and Disturbed Sound Processing in the Auditory Brainstem of Fragile X Mice.
Q30536899FMRP regulates neurotransmitter release and synaptic information transmission by modulating action potential duration via BK channels
Q30432990Failed stabilization for long-term potentiation in the auditory cortex of FMR1 knockout mice
Q47626153Fragile X Mental Retardation Protein Restricts Small Dye Iontophoresis Entry into Central Neurons.
Q38097197Fragile X mental retardation protein and synaptic plasticity
Q48915976Fragile X mental retardation protein controls ion channel expression and activity
Q34952541Fragile X mental retardation protein regulates protein expression and mRNA translation of the potassium channel Kv4.2.
Q30448604Fragile X syndrome: mechanistic insights and therapeutic avenues regarding the role of potassium channels.
Q30410502From FMRP function to potential therapies for fragile X syndrome
Q50561718Genetic upregulation of BK channel activity normalizes multiple synaptic and circuit defects in a mouse model of fragile X syndrome.
Q30469392Gradients and modulation of K(+) channels optimize temporal accuracy in networks of auditory neurons
Q64289005Homeostatic Intrinsic Plasticity Is Functionally Altered in Fmr1 KO Cortical Neurons
Q48098924Identification and characterization of site-specific N-glycosylation in the potassium channel Kv3.1b.
Q91494891Identification of a molecular locus for normalizing dysregulated GABA release from interneurons in the Fragile X brain
Q47550815Imbalance of synaptic actin dynamics as a key to the Fragile X syndrome?
Q37564195Impaired activity-dependent neural circuit assembly and refinement in autism spectrum disorder genetic models
Q30440653Impaired critical period plasticity in primary auditory cortex of fragile X model mice
Q30406616In vivo synaptic transmission and morphology in mouse models of Tuberous sclerosis, Fragile X syndrome, Neurofibromatosis type 1, and Costello syndrome
Q34435526Increasing our understanding of human cognition through the study of Fragile X Syndrome
Q28115339Independent role for presynaptic FMRP revealed by an FMR1 missense mutation associated with intellectual disability and seizures
Q38441936Integrated transcriptome analysis of human iPS cells derived from a fragile X syndrome patient during neuronal differentiation
Q97522071Intellectual Disability and Potassium Channelopathies: A Systematic Review
Q41468658Intense and specialized dendritic localization of the fragile X mental retardation protein in binaural brainstem neurons: a comparative study in the alligator, chicken, gerbil, and human
Q47681198Kv3 Channels: Enablers of Rapid Firing, Neurotransmitter Release, and Neuronal Endurance
Q30416917Linking neural activity and molecular oscillations in the SCN.
Q37381803Loss of functional A-type potassium channels in the dendrites of CA1 pyramidal neurons from a mouse model of fragile X syndrome
Q30357779Matrix metalloproteinase-9 deletion rescues auditory evoked potential habituation deficit in a mouse model of Fragile X Syndrome
Q89624618Mechanisms underlying auditory processing deficits in Fragile X syndrome
Q92765746Modulators of Kv3 Potassium Channels Rescue the Auditory Function of Fragile X Mice
Q38639448Multifarious Functions of the Fragile X Mental Retardation Protein
Q64950869Neuroligin 1, 2, and 3 Regulation at the Synapse: FMRP-Dependent Translation and Activity-Induced Proteolytic Cleavage.
Q38884036Neuron class-specific requirements for Fragile X Mental Retardation Protein in critical period development of calcium signaling in learning and memory circuitry
Q37127783Physiological modulators of Kv3.1 channels adjust firing patterns of auditory brain stem neurons
Q92308939Polysomnographic Findings in Fragile X Syndrome Children with EEG Abnormalities
Q30464105Potassium channel modulation and auditory processing
Q42290506Reduced Lateral Inhibition Impairs Olfactory Computations and Behaviors in a Drosophila Model of Fragile X Syndrome
Q58718525Sensory Processing Phenotypes in Fragile X Syndrome
Q90029168Subtle differences in synaptic transmission in medial nucleus of trapezoid body neurons between wild-type and Fmr1 knockout mice
Q27023257Targeted pharmacological treatment of autism spectrum disorders: fragile X and Rett syndromes
Q35680726Targeted treatments for fragile X syndrome
Q38775856The need for new approaches in CNS drug discovery: Why drugs have failed, and what can be done to improve outcomes
Q38098906The translation of translational control by FMRP: therapeutic targets for FXS.
Q27337360Therapeutic Strategies in Fragile X Syndrome: From Bench to Bedside and Back
Q35614072Therapeutic strategies in fragile X syndrome: dysregulated mGluR signaling and beyond
Q47660831Tonotopic alterations in inhibitory input to the medial nucleus of the trapezoid body in a mouse model of Fragile X syndrome.
Q91062840Tsc1 represses parvalbumin expression and fast-spiking properties in somatostatin lineage cortical interneurons
Q58800979Unraveling the Pathways to Neuronal Homeostasis and Disease: Mechanistic Insights into the Role of RNA-Binding Proteins and Associated Factors
Q58617074Voltage-Independent SK Channel Dysfunction Causes Neuronal Hyperexcitability in the Hippocampus of KO mice

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