Impact of apolipoprotein E ε4 and HIV on cognition and brain atrophy: antagonistic pleiotropy and premature brain aging

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Impact of apolipoprotein E ε4 and HIV on cognition and brain atrophy: antagonistic pleiotropy and premature brain aging is …
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scholarly articleQ13442814

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P8978DBLP publication IDjournals/neuroimage/ChangASJNME11
P356DOI10.1016/J.NEUROIMAGE.2011.07.010
P932PMC publication ID3171637
P698PubMed publication ID21803164
P5875ResearchGate publication ID51534455

P50authorEric N MillerQ56566453
P2093author name stringL Chang
T Ernst
C S Jiang
H Nakama
M Andres
J Sadino
P2860cites workCerebellar atrophy associated with human immunodeficiency virus infectionQ45376096
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APOE genotype and cognitive functioning in a large age-stratified population sample.Q51908317
Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filamentsQ59053832
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HIV dementia and apolipoprotein EQ73428371
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Effects of nadir CD4 count and duration of human immunodeficiency virus infection on brain volumes in the highly active antiretroviral therapy eraQ24632654
Better memory and neural efficiency in young apolipoprotein E epsilon4 carriersQ28271343
Apolipoprotein (apo) E4 enhances HIV-1 cell entry in vitro, and the APOE epsilon4/epsilon4 genotype accelerates HIV disease progressionQ28284354
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The human immunodeficiency virus reduces network capacity: acoustic noise effectQ30494107
A unified approach for morphometric and functional data analysis in young, old, and demented adults using automated atlas-based head size normalization: reliability and validation against manual measurement of total intracranial volumeQ30970553
HIV infection and aging independently affect brain function as measured by functional magnetic resonance imagingQ33583519
ApoE4 decreases spine density and dendritic complexity in cortical neurons in vivo.Q33758196
Thinning of the cerebral cortex visualized in HIV/AIDS reflects CD4+ T lymphocyte declineQ34098327
Lower brain glutamate is associated with cognitive deficits in HIV patients: A new mechanism for HIV‐associated neurocognitive disorderQ34257820
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APOE epsilon4 and MBL-2 O/O genotypes are associated with neurocognitive impairment in HIV-infected plasma donorsQ34714286
Compromised fronto-striatal functioning in HIV: an fMRI investigation of semantic event sequencingQ34744492
3D pattern of brain atrophy in HIV/AIDS visualized using tensor-based morphometryQ35401301
Updated research nosology for HIV-associated neurocognitive disordersQ35755761
Apolipoprotein E and traumatic brain injury in a military population: evidence of a neuropsychological compensatory mechanism?Q36226653
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Mapping cerebellar degeneration in HIV/AIDSQ37268035
Decreased brain dopamine transporters are related to cognitive deficits in HIV patients with or without cocaine abuseQ37314434
Declined neural efficiency in cognitively stable human immunodeficiency virus patientsQ37325321
Human immunodeficiency virus downregulates podocyte apoE expressionQ37337364
APOE genotype-specific differences in the innate immune responseQ37434999
Brain deposition of beta-amyloid is a common pathologic feature in HIV positive patientsQ38443652
The apolipoprotein E epsilon4 allele and memory performance in HIV-1 seropositive subjects: differences at baseline but not after acute oral lorazepam challengeQ40064649
Expression of human apolipoprotein E3 or E4 in the brains of Apoe-/- mice: isoform-specific effects on neurodegeneration.Q41671941
Human apolipoprotein E isoform-specific differences in neuronal sprouting in organotypic hippocampal cultureQ41705313
Abnormal contingent negative variation in HIV patients receiving antiretroviral therapyQ42112369
Adaptation of the attention network in human immunodeficiency virus brain injuryQ43489247
Does possession of apolipoprotein E ɛ4 benefit cognitive function in healthy young adults?Q44699908
Neural correlates of attention and working memory deficits in HIV patients.Q45029853
Whole brain imaging of HIV-infected patients: quantitative analysis of magnetization transfer ratio histogram and fractional brain volume.Q45048077
Lowest ever CD4 lymphocyte count (CD4 nadir) as a predictor of current cognitive and neurological status in human immunodeficiency virus type 1 infection--The Hawaii Aging with HIV CohortQ45181283
Differential effects of the APOE genotype on brain function across the lifespanQ45239574
Association between apolipoprotein E4 genotype and human immunodeficiency virus-associated dementia in younger adults starting antiretroviral therapy in South AfricaQ45373223
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectpleiotropyQ1134884
P304page(s)1017-1027
P577publication date2011-07-21
P1433published inNeuroImageQ1981225
P1476titleImpact of apolipoprotein E ε4 and HIV on cognition and brain atrophy: antagonistic pleiotropy and premature brain aging
P478volume58

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