| P50 | author | Tony Wyss-Coray | Q23782672 |
| | Lennart Mucke | Q56825889 |
| | Matthias Orth | Q42682284 |
| P2093 | author name string | R W Mahley | |
| | S Bellosta | |
| | R E Pitas | |
| | M Buttini | |
| | H Akeefe | |
| P2860 | cites work | Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease | Q22248076 |
| | Apolipoprotein E is localized to the cytoplasm of human cortical neurons: a light and electron microscopic study | Q24319783 |
| | Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families | Q27860677 |
| | Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium | Q28252389 |
| | Novel role of human CD4 molecule identified in neurodegeneration | Q46222222 |
| | Neurodegeneration in the central nervous system of apoE-deficient mice | Q46455236 |
| | Differential cellular accumulation/retention of apolipoprotein E mediated by cell surface heparan sulfate proteoglycans. Apolipoproteins E3 and E2 greater than e4. | Q46580059 |
| | Behavioural, physiological and morphological analysis of a line of apolipoprotein E knockout mouse | Q48024701 |
| | Levels and alternative splicing of amyloid beta protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer's disease | Q48069116 |
| | Axonal disruption and aberrant localization of tau protein characterize the neuropil pathology of Alzheimer's disease | Q48189763 |
| | Glial fibrillary acidic protein-apolipoprotein E (apoE) transgenic mice: astrocyte-specific expression and differing biological effects of astrocyte-secreted apoE3 and apoE4 lipoproteins. | Q48477194 |
| | Apolipoprotein E isoform-specific differences in outcome from focal ischemia in transgenic mice | Q48492024 |
| | Motor and cognitive deficits in apolipoprotein E-deficient mice after closed head injury | Q48624330 |
| | Loss of the presynaptic vesicle protein synaptophysin in hippocampus correlates with cognitive decline in Alzheimer disease. | Q48650804 |
| | Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease | Q48795523 |
| | Expression of apolipoprotein E in normal and diverse neurodegenerative disease brain. | Q48960211 |
| | Neurons of the human frontal cortex display apolipoprotein E immunoreactivity: implications for Alzheimer's disease | Q49082479 |
| | Apolipoprotein E epsilon4 and the risk of dementia with stroke. A population-based investigation. | Q50970844 |
| | Synergistic effects of traumatic head injury and apolipoprotein-epsilon 4 in patients with Alzheimer's disease. | Q53204218 |
| | Association of apolipoprotein E polymorphism with outcome after head injury. | Q53777504 |
| | Hippocampal damage produced by systemic injections of domoic acid in mice. | Q54083012 |
| | Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments | Q59053832 |
| | Synaptotrophic effects of human amyloid β protein precursors in the cortex of transgenic mice | Q60796700 |
| | Isolation and characterization of apolipoprotein E | Q69553515 |
| | Human apolipoprotein E. The complete amino acid sequence | Q70312109 |
| | Human E apoprotein heterogeneity. Cysteine-arginine interchanges in the amino acid sequence of the apo-E isoforms | Q70875567 |
| | Complete cerebral ischemia with short-term survival in rat induced by cardiac arrest. II. Extracellular and intracellular accumulation of apolipoproteins E and J in the brain | Q72346999 |
| | Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis | Q73500603 |
| | Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid | Q28279517 |
| | Apolipoprotein E: cholesterol transport protein with expanding role in cell biology | Q28294791 |
| | Selective alterations in the cellular distribution of apolipoprotein E immunoreactivity following transient cerebral ischaemia in the rat | Q28569838 |
| | Stable expression and secretion of apolipoproteins E3 and E4 in mouse neuroblastoma cells produces differential effects on neurite outgrowth | Q28771743 |
| | Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment | Q29547294 |
| | Genetic determinants of susceptibility to excitotoxic cell death: implications for gene targeting approaches | Q30454438 |
| | Neuropathological changes in scrapie and Alzheimer's disease are associated with increased expression of apolipoprotein E and cathepsin D in astrocytes | Q33360009 |
| | Isoform-specific effects of human apolipoprotein E on brain function revealed in ApoE knockout mice: increased susceptibility of females | Q33563135 |
| | Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation | Q34225777 |
| | Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3 | Q34229659 |
| | Excitatory amino acids as a final common pathway for neurologic disorders. | Q34321926 |
| | High and low annealing temperatures increase both specificity and yield in touchdown and stepdown PCR. | Q34386574 |
| | Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system | Q34559847 |
| | Expression of apolipoprotein E during nerve degeneration and regeneration | Q35591346 |
| | Specific regional transcription of apolipoprotein E in human brain neurons | Q35745315 |
| | Macrophage-specific expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic apolipoprotein E-null mice | Q35765799 |
| | Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice. | Q36840098 |
| | Amyloid precursor proteins protect neurons of transgenic mice against acute and chronic excitotoxic injuries in vivo. | Q36858269 |
| | Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells | Q37011453 |
| | Apolipoprotein E mRNA is abundant in the brain and adrenals, as well as in the liver, and is present in other peripheral tissues of rats and marmosets | Q37672903 |
| | Excitatory amino acid neurotoxicity and neurodegenerative disease | Q37989602 |
| | Polymorphism of apolipoprotein E and occurrence of dysbetalipoproteinaemia in man | Q40108225 |
| | Apolipoprotein E: impact of cytoskeletal stability in neurons and the relationship to Alzheimer's disease. | Q40540743 |
| | Central nervous system damage produced by expression of the HIV-1 coat protein gp120 in transgenic mice. | Q40717934 |
| | Hypothesis: microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype | Q40817463 |
| | Amyloid beta-protein, APOE genotype and head injury | Q40983097 |
| | Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides | Q41172424 |
| | Human apolipoprotein E: the Alzheimer's disease connection. | Q41239700 |
| | The inhibitory effect of apolipoprotein E4 on neurite outgrowth is associated with microtubule depolymerization | Q41308477 |
| | An improved T1/A ribonuclease protection assay. | Q41485791 |
| | Molecular biology of glutamate receptors in the central nervous system and their role in excitotoxicity, oxidative stress and aging | Q41729394 |
| | An antibody against phosphorylated neurofilaments identifies a subset of damaged association axons in Alzheimer's disease. | Q41922551 |
| | Evidence for normal aging of the septo-hippocampal cholinergic system in apoE (-/-) mice but impaired clearance of axonal degeneration products following injury | Q42456741 |
| | Correlations of synaptic and pathological markers with cognition of the elderly | Q42478788 |
| | Plastic neuronal remodeling is impaired in patients with Alzheimer's disease carrying apolipoprotein epsilon 4 allele | Q42528671 |
| | A Method for Obtaining Cerebrospinal Fluid from Mice | Q43902483 |
| | Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro | Q45081026 |
| | Quantitative assessment of the synaptophysin immuno-reactivity of the cortical neuropil in various neurodegenerative disorders with dementia. | Q45290696 |
| | Spectrum of human immunodeficiency virus-associated neocortical damage | Q45871285 |
| | Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain. | Q46034439 |
| | Indicator expression directed by regulatory sequences of the glial fibrillary acidic protein (GFAP) gene: in vivo comparison of distinct GFAP-lacZ transgenes | Q46156203 |
| | Transgenic mice expressing beta-galactosidase in mature neurons under neuron-specific enolase promoter control | Q46168479 |
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | neurodegeneration | Q1755122 |
| P304 | page(s) | 4867-4880 | |
| P577 | publication date | 1999-06-01 | |
| P1433 | published in | Journal of Neuroscience | Q1709864 |
| P1476 | title | Expression of human apolipoprotein E3 or E4 in the brains of Apoe-/- mice: isoform-specific effects on neurodegeneration | |
| P478 | volume | 19 | |