Amyloid precursor proteins protect neurons of transgenic mice against acute and chronic excitotoxic injuries in vivo.

scientific article published on May 1997

Amyloid precursor proteins protect neurons of transgenic mice against acute and chronic excitotoxic injuries in vivo. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0306-4522(96)00553-2
P8608Fatcat IDrelease_vmlku2otmnd4lcfkh7ycespqea
P698PubMed publication ID9135095

P50authorEliezer MasliahQ28324209
Carmela R AbrahamQ47844873
Lennart MuckeQ56825889
P2093author name stringE M Rockenstein
M Mallory
E Sheldon
C E Westland
I Veinberg
P2860cites workAlzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor proteinQ22251280
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Prevention of HIV-1 gp120-induced neuronal damage in the central nervous system of transgenic mice by the NMDA receptor antagonist memantineQ28290906
Behavioral and anatomical deficits in mice homozygous for a modified beta-amyloid precursor protein geneQ28586800
beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activityQ28593175
Axonal sprouting induced in the sciatic nerve by the amyloid precursor protein (APP) and other antiproteases.Q31001104
Amyloid precursor protein is localized in growing neurites of neonatal rat brainQ33193350
Reactive synaptogenesis assessed by synaptophysin immunoreactivity is associated with GAP-43 in the dentate gyrus of the adult ratQ33321887
Early Alzheimer disease-like histopathology increases in frequency with age in mice transgenic for beta-APP751.Q34329828
Heterogeneity of high affinity uptake of L-glutamate and L-aspartate in the mammalian central nervous systemQ35270604
Increase of synaptic density and memory retention by a peptide representing the trophic domain of the amyloid beta/A4 protein precursorQ35638734
The envelope glycoprotein of human immunodeficiency virus type 1 stimulates release of neurotoxins from monocytesQ36198708
Human immunodeficiency virus type 1 coat protein neurotoxicity mediated by nitric oxide in primary cortical culturesQ36233456
Protection against HIV-1 gp120-induced brain damage by neuronal expression of human amyloid precursor proteinQ36364676
Calcium-destabilizing and neurodegenerative effects of aggregated beta-amyloid peptide are attenuated by basic FGF.Q36753784
Neurotrophic and neuroprotective effects of hAPP in transgenic miceQ36798319
Protein inhibitors of proteinases from brainQ36836252
Dysregulation of signal transduction pathways as a potential mechanism of nervous system alterations in HIV-1 gp120 transgenic mice and humans with HIV-1 encephalitisQ37351753
Cell-derived proteases and protease inhibitors as regulators of neurite outgrowthQ38203041
Biological differences between ischemia, hypoglycemia, and epilepsyQ39550601
HIV-related neuronal injury. Potential therapeutic intervention with calcium channel antagonists and NMDA antagonistsQ40654337
Alzheimer's disease: a central role for amyloidQ40701623
Central nervous system damage produced by expression of the HIV-1 coat protein gp120 in transgenic mice.Q40717934
Glial calciumQ40781991
Neurite outgrowth activity of protease nexin-1 on neuroblastoma cells requires thrombin inhibitionQ41223116
Secreted forms of beta-amyloid precursor protein protect against ischemic brain injuryQ41451125
Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1.Q41710744
Beta-amyloid precursor protein isoforms in various rat brain regions and during brain developmentQ41966102
The secreted form of the Alzheimer's amyloid precursor protein with the Kunitz domain is protease nexin-II.Q43466747
Sham transplantation protects against 6-hydroxydopamine-induced dopaminergic toxicity in rats: behavioral and morphological evidenceQ43536135
Formation of beta-amyloid protein deposits in brains of transgenic miceQ44671370
Patterns of aberrant sprouting in Alzheimer's diseaseQ45166469
Spectrum of human immunodeficiency virus-associated neocortical damageQ45871285
Protease nexin-II, a potent antichymotrypsin, shows identity to amyloid beta-protein precursorQ46359315
Reduction of neurological damage by a peptide segment of the amyloid beta/A4 protein precursor in a rabbit spinal cord ischemia modelQ46736730
Levels and alternative splicing of amyloid beta protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer's diseaseQ48069116
Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor proteinQ48342880
In vivo effects of beta-amyloid implants in rodents: lack of potentiation of damage associated with transient global forebrain ischemiaQ48454195
Hippocampal damage produced by systemic injections of domoic acid in mice.Q54083012
Molecular Genetics of Alzheimer's DiseaseQ56770140
gp120 HIV envelope glycoprotein increases the production of nitric oxide in human monocyte-derived macrophagesQ57616786
Synaptotrophic effects of human amyloid β protein precursors in the cortex of transgenic miceQ60796700
Requirement for macrophages in neuronal injury induced by HIV envelope protein gp120Q67572030
Excitatory amino acid receptors, neural membrane phospholipid metabolism and neurological disordersQ68268628
Amyloid precursor protein gene mutation at codon 670/671 in familial Alzheimer's disease in SwedenQ72524640
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectexcitotoxicityQ901117
P304page(s)135-146
P577publication date1997-05-01
P1433published inNeuroscienceQ15708571
P1476titleAmyloid precursor proteins protect neurons of transgenic mice against acute and chronic excitotoxic injuries in vivo
P478volume78

Reverse relations

cites work (P2860)
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