GRP94 is essential for mesoderm induction and muscle development because it regulates insulin-like growth factor secretion

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GRP94 is essential for mesoderm induction and muscle development because it regulates insulin-like growth factor secretion is …
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scholarly articleQ13442814

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P356DOI10.1091/MBC.E07-03-0275
P932PMC publication ID1995707
P698PubMed publication ID17634284

P2093author name stringBirgitte B Simen
Sherry Wanderling
Yair Argon
Tali Gidalevitz
Olga Ostrovsky
Noreen T Ahmed
Shawn M Vogen
P2860cites workA vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryoQ24564561
Heat shock protein gp96 is a master chaperone for toll-like receptors and is important in the innate function of macrophagesQ24609722
Eomesodermin is required for mouse trophoblast development and mesoderm formationQ28507697
Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogeneQ28512170
The type I activin receptor ActRIB is required for egg cylinder organization and gastrulation in the mouseQ28586850
Murine gastrulation requires HNF-4 regulated gene expression in the visceral endoderm: tetraploid rescue of Hnf-4(-/-) embryosQ28588392
Multiple roles for activin-like kinase-2 signaling during mouse embryogenesisQ28591124
Mice lacking HSP90beta fail to develop a placental labyrinthQ28592177
Oct-4 transcription factor is differentially expressed in the mouse embryo during establishment of the first two extraembryonic cell lineages involved in implantationQ28593883
Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscleQ29615169
Expression pattern of the mouse T gene and its role in mesoderm formationQ29618646
Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)Q29619910
Role of insulin-like growth factors in embryonic and postnatal growthQ29620034
Expression of the T-box gene Eomesodermin during early mouse development.Q30630109
The bHLH class protein pMesogenin1 can specify paraxial mesoderm phenotypes.Q30874654
SHEPHERD is the Arabidopsis GRP94 responsible for the formation of functional CLAVATA proteinsQ33336944
Endoplasmic reticulum chaperone gp96 is required for innate immunity but not cell viabilityQ34093483
The insulin-like growth factor system and cancerQ34200058
Differentiation of pluripotent embryonic stem cells into cardiomyocytes.Q34778309
Biology of insulin-like growth factors in development.Q35639975
Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor smad2.Q36258971
Membrane biogenesis during B cell differentiation: most endoplasmic reticulum proteins are expressed coordinatelyQ36383421
Embryonic expression of Lim-1, the mouse homolog of Xenopus Xlim-1, suggests a role in lateral mesoderm differentiation and neurogenesisQ36721320
A protein kinase isolated from porcine brain microvessels is similar to a class of heat-shock proteinsQ36726411
Overexpression of the stress protein Grp94 reduces cardiomyocyte necrosis due to calcium overload and simulated ischemiaQ40659239
IGF-II promotes mesoderm formationQ40842744
Reduced amount of the glucose-regulated protein GRP94 in skeletal myoblasts results in loss of fusion competenceQ40896563
Interaction of radicicol with members of the heat shock protein 90 family of molecular chaperonesQ40930400
Post-translational processing of the insulin-like growth factor-2 precursor. Analysis of O-glycosylation and endoproteolysisQ41026364
Pattern of the insulin-like growth factor II gene expression during early mouse embryogenesisQ41173042
Regulation of the glucose-regulated protein genes by beta-mercaptoethanol requires de novo protein synthesis and correlates with inhibition of protein glycosylationQ41467340
Establishment of a Chinese hamster ovary cell line that expresses grp78 antisense transcripts and suppresses A23187 induction of both GRP78 and GRP94Q41592653
Competitive inhibition of a set of endoplasmic reticulum protein genes (GRP78, GRP94, and ERp72) retards cell growth and lowers viability after ionophore treatmentQ41676067
In vitro differentiation of embryonic stem cells into hepatocyte-like cells identified by cellular uptake of indocyanine greenQ43920142
Cardiac-specific expression of calcineurin reverses embryonic lethality in calreticulin-deficient mouseQ44177975
Immunolocalization and heart levels of GRP94 in the mouse during post-implantation developmentQ44868949
Expression of the glucose-regulated proteins (GRP94 and GRP78) in differentiated and undifferentiated mouse embryonic cells and the use of the GRP78 promoter as an expression system in embryonic cells.Q45949129
BMP signaling plays a role in visceral endoderm differentiation and cavitation in the early mouse embryo.Q46724342
Establishment of dorsal-ventral polarity in the Drosophila embryo: the induction of polarity by the Toll gene productQ47072878
The transcription factor HNF3beta is required in visceral endoderm for normal primitive streak morphogenesisQ47812788
MyoD cannot compensate for the absence of myogenin during skeletal muscle differentiation in murine embryonic stem cells.Q51069969
Activation of an unfolded protein response during differentiation of antibody-secreting B cells.Q52113898
The Toll/IL-1 receptor binding protein MyD88 is required for Xenopus axis formation.Q52164552
Hex: a homeobox gene revealing peri-implantation asymmetry in the mouse embryo and an early transient marker of endothelial cell precursors.Q52191962
Differential expression of BMP receptors in early mouse development.Q52193152
Ontogenic changes in the circulating concentrations of insulin-like growth factor (IGF)-I, IGF-II, and IGF-binding proteins in the chicken embryo.Q52194807
A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting.Q52241373
Sequential interaction of the chaperones BiP and GRP94 with immunoglobulin chains in the endoplasmic reticulumQ59060210
Mapping of the genes for human endoplasmic reticular heat shock protein gp96/grp94Q60021890
Transcriptional regulation of two genes specifically induced by glucose starvation in a hamster mutant fibroblast cell lineQ67246516
Chromosomal assignment of the gene encoding the mouse tumor rejection antigen gp96Q68487713
Histochemical localization of IGF-I and -II mRNA in the developing rat embryoQ68703081
Structure and assembly of the endoplasmic reticulum. The synthesis of three major endoplasmic reticulum proteins during lipopolysaccharide-induced differentiation of murine lymphocytesQ69939120
Developmentally regulated expression of insulin-like growth factors by differentiated murine teratocarcinomas and extraembryonic mesodermQ70020138
Depletion of intracellular calcium stores by calcium ionophore A23187 induces the genes for glucose-regulated proteins in hamster fibroblastsQ70355655
Expression of a glucose-regulated cell surface protein in early mouse embryosQ70381386
Expression levels of stress protein gp96 are not limiting for major histocompatibility complex class I-restricted antigen presentationQ71069075
Embryonic stem cells express neuronal properties in vitroQ72189372
nodal expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulationQ73124215
Differentiation of embryonic stem cells into adipocytes in vitroQ73457048
Phylogenetic conservation of the molecular and immunological properties of the chaperones gp96 and hsp70Q73665310
Ligand interactions in the adenosine nucleotide-binding domain of the Hsp90 chaperone, GRP94. I. Evidence for allosteric regulation of ligand bindingQ73804897
Radicicol-sensitive peptide binding to the N-terminal portion of GRP94Q74633065
Generation of a mammalian cell line deficient in glucose-regulated protein stress induction through targeted ribozyme driven by a stress-inducible promoterQ95806626
P433issue10
P921main subjectpreproinsulinQ7240673
P304page(s)3764-3775
P577publication date2007-07-18
P1433published inMolecular Biology of the CellQ2338259
P1476titleGRP94 is essential for mesoderm induction and muscle development because it regulates insulin-like growth factor secretion
P478volume18

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cites work (P2860)
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