Nuclear translocation of urokinase-type plasminogen activator

scientific article

Nuclear translocation of urokinase-type plasminogen activator is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1182/BLOOD-2007-07-104455
P932PMC publication ID2435680
P698PubMed publication ID18337556

P50authorDouglas CinesQ16204220
Serge YarovoiQ124218059
Khalil BdeirQ124218060
Victoria StepanovaQ125230015
Michael S. MarksQ38305771
P2093author name stringAbd Al-Roof Higazi
Yelena Parfyonova
Tatiana Lebedeva
Sergei Zaitsev
Inna Dumler
Alice Kuo
Vsevolod A Tkachuk
Sergei Tkachuk
P2860cites workThe chemotactic action of urokinase on smooth muscle cells is dependent on its kringle domain. Characterization of interactions and contribution to chemotaxisQ22253459
Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysisQ24299135
The angiogenic function of nucleolin is mediated by vascular endothelial growth factor and nonmuscle myosinQ24300666
Nucleolin is a receptor that mediates antiangiogenic and antitumor activity of endostatinQ24317515
Recycling of the urokinase receptor upon internalization of the uPA:serpin complexesQ24532196
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
The urokinase plasminogen activator receptor in the regulation of the actin cytoskeleton and cell motilityQ28212178
The anti-HIV cytokine midkine binds the cell surface-expressed nucleolin as a low affinity receptorQ28216327
The urokinase plasminogen activator and its receptor: role in cell growth and apoptosisQ28235072
Pleiotrophin inhibits HIV infection by binding the cell surface-expressed nucleolinQ28271787
Surface nucleolin participates in both the binding and endocytosis of lactoferrin in target cellsQ43551857
Binding of urokinase to low density lipoprotein-related receptor (LRP) regulates vascular smooth muscle cell contractionQ44097437
The receptor-binding sequence of urokinase. A biological function for the growth-factor module of proteasesQ44354200
The kringle stabilizes urokinase binding to the urokinase receptorQ47735737
Nucleolin interacts with several ribosomal proteins through its RGG domain.Q47828267
Protein phosphorylation sites regulate the function of the bipartite NLS of nucleolinQ48953948
Nuclear export of proteins: the role of nuclear retention.Q49136533
Nuclei from rat liver: isolation method that combines purity with high yieldQ49488035
Direct interaction of the kringle domain of urokinase-type plasminogen activator (uPA) and integrin alpha v beta 3 induces signal transduction and enhances plasminogen activation.Q51809541
LDL receptor-related protein internalizes and degrades uPA-PAI-1 complexes and is essential for embryo implantationQ52478181
Anchorage of HIV on permissive cells leads to coaggregation of viral particles with surface nucleolin at membrane raft microdomains.Q53970125
Enzymatic properties of single-chain and two-chain forms of a Lys158----Glu158 mutant of urokinase-type plasminogen activatorQ69914168
Urokinase receptor antagonists inhibit angiogenesis and primary tumor growth in syngeneic miceQ71067669
Low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor mediates cellular uptake of pro-urokinaseQ72098003
Induction of plasminogen activator inhibitor-1 by urokinase in lung epithelial cellsQ73140073
Induction in human osteoblastic cells (SaOS2) of the early response genes fos, jun, and myc by the amino terminal fragment (ATF) of urokinaseQ73589777
Activation of p38 MAP-kinase and caldesmon phosphorylation are essential for urokinase-induced human smooth muscle cell migrationQ77873801
Structure and function of the plasminogen/plasmin systemQ81668319
Nucleolin: a multifunctional major nucleolar phosphoproteinQ28295172
Human DNA helicase IV is nucleolin, an RNA helicase modulated by phosphorylationQ28295537
Ecto-protein kinase substrate p120 revealed as the cell-surface-expressed nucleolar phosphoprotein Nopp140: a candidate protein for extracellular Ca2+-sensingQ28365833
Urokinase plasminogen activator in injured adventitia increases the number of myofibroblasts and augments early proliferationQ28565046
A 110-kD nuclear shuttling protein, nucleolin, binds to the neurite-promoting IKVAV site of laminin-1Q28574881
Multiply attenuated lentiviral vector achieves efficient gene delivery in vivoQ29616612
Major nucleolar proteins shuttle between nucleus and cytoplasmQ29620425
Regulation of dna replication after heat shock by replication protein a-nucleolin interactionsQ30673624
Urokinase-induced mitogenesis is mediated by casein kinase 2 and nucleolin.Q30828562
Novel checkpoint response to genotoxic stress mediated by nucleolin-replication protein a complex formationQ31150971
In vitro selection of single-stranded DNA aptamers that bind human pro-urokinaseQ33209224
FGF-1 and FGF-2 require the cytosolic chaperone Hsp90 for translocation into the cytosol and the cell nucleusQ33234533
Structure and functions of nucleolin.Q33536089
Molecular dissection of nucleolin's role in growth and cell proliferation: new insightsQ33764019
Alpha-smooth muscle actin expression upregulates fibroblast contractile activityQ33946717
uPAR: a versatile signalling orchestratorQ34162183
Nuclear targeting by the growth factor midkineQ34286252
Tumor-associated urokinase-type plasminogen activator: biological and clinical significanceQ35777083
Nucleolin expressed at the cell surface is a marker of endothelial cells in angiogenic blood vesselsQ36324866
Nucleolin as activator of human papillomavirus type 18 oncogene transcription in cervical cancerQ36371206
Determination of the functional domains involved in nucleolar targeting of nucleolinQ37376748
Nucleolin is a matrix attachment region DNA-binding protein that specifically recognizes a region with high base-unpairing potentialQ38300450
Urokinase-derived peptides regulate vascular smooth muscle contraction in vitro and in vivoQ38310818
Anti-angiogenic activity of the recombinant kringle domain of urokinase and its specific entry into endothelial cells.Q38358693
The receptor for urokinase-plasminogen activator.Q39505756
Proteomic identification of lynchpin urokinase plasminogen activator receptor protein interactions associated with epithelial cancer malignancy.Q40165011
Induction of p53 by urokinase in lung epithelial cellsQ40413239
Translocation of FGF-1 and FGF-2 across vesicular membranes occurs during G1-phase by a common mechanismQ40509934
Convergence of the adhesive and fibrinolytic systems: recognition of urokinase by integrin alpha Mbeta 2 as well as by the urokinase receptor regulates cell adhesion and migrationQ40695132
Urokinase induces its own expression in Beas2B lung epithelial cellsQ40718884
Identification of nucleolin as a new L-selectin ligandQ40764932
Nuclear localization of EGF receptor and its potential new role as a transcription factorQ40782527
A 110-kDa nuclear shuttle protein, nucleolin, specifically binds to adeno-associated virus type 2 (AAV-2) capsidQ40954235
siRNA Selection Server: an automated siRNA oligonucleotide prediction serverQ41010535
Induction of alpha-smooth muscle actin by transforming growth factor-beta 1 in quiescent human breast gland fibroblasts. Implications for myofibroblast generation in breast neoplasiaQ41548309
A protein partially expressed on the surface of HepG2 cells that binds lipoproteins specifically is nucleolinQ41717933
Plasminogen activators, their inhibitors, and urokinase receptor emerge in late stages of melanocytic tumor progressionQ42754658
Genetic deficiency in low density lipoprotein receptor-related protein confers cellular resistance to Pseudomonas exotoxin A. Evidence that this protein is required for uptake and degradation of multiple ligandsQ42807171
Regions involved in binding of urokinase-type-1 inhibitor complex and pro-urokinase to the endocytic alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein. Evidence that the urokinase receptor protects pro-urokinase againstQ42833221
Plasmin-dependent elimination of the growth-factor-like domain in urokinase causes its rapid cellular uptake and degradation.Q42999092
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectplasminogenQ107129060
P304page(s)100-110
P577publication date2008-03-12
P1433published inBloodQ885070
P1476titleNuclear translocation of urokinase-type plasminogen activator
P478volume112

Reverse relations

cites work (P2860)
Q34385625Aggregated low-density lipoprotein induce impairment of the cytoskeleton dynamics through urokinase-type plasminogen activator/urokinase-type plasminogen activator receptor in human vascular smooth muscle cell
Q39368829Angiogenesis biomarkers and their targeting ligands as potential targets for tumor angiogenesis.
Q37566249Chronic myeloproliferative diseases with and without the Ph chromosome: some unresolved issues.
Q41197179Copine-7 binds to the cell surface receptor, nucleolin, and regulates ciliogenesis and Dspp expression during odontoblast differentiation.
Q39028976Current status of biomarker and targeted nanoparticle development: The precision oncology approach for pancreatic cancer therapy
Q33774606DNA damage-induced translocation of S100A11 into the nucleus regulates cell proliferation
Q35005500Disrupting the oncogenic synergism between nucleolin and Ras results in cell growth inhibition and cell death
Q37529843Emerging drugs for the therapy of primary and post essential thrombocythemia, post polycythemia vera myelofibrosis
Q38367291Enhancing FTS (Salirasib) efficiency via combinatorial treatment
Q36053965Expression of Nucleolin Affects Microtubule Dynamics
Q36112952Fibulin-5 binds urokinase-type plasminogen activator and mediates urokinase-stimulated β1-integrin-dependent cell migration.
Q37152354Human tissue factor pathway inhibitor-2 is internalized by cells and translocated to the nucleus by the importin system
Q38303924Interfering with the interaction between ErbB1, nucleolin and Ras as a potential treatment for glioblastoma.
Q37131462Multifunctional roles of urokinase plasminogen activator (uPA) in cancer stemness and chemoresistance of pancreatic cancer.
Q34656695Novel mechanism regulating endothelial permeability via T-cadherin-dependent VE-cadherin phosphorylation and clathrin-mediated endocytosis
Q34475097Nucleolin mediates the antiangiogenesis effect of the pseudopeptide N6L
Q50739041Proteomic analysis reveals a proteolytic feedback loop in murine seminal fluid.
Q34606581Regulation of arterial remodeling and angiogenesis by urokinase-type plasminogen activator.
Q37372370Senescence, apoptosis, and stem cell biology: the rationale for an expanded view of intracrine action
Q33478425Structure-function analysis of nucleolin and ErbB receptors interactions
Q28472975Suppression of tumor growth and angiogenesis by a specific antagonist of the cell-surface expressed nucleolin
Q33784401Surface expressed nucleolin is constantly induced in tumor cells to mediate calcium-dependent ligand internalization
Q33614407Targeting surface nucleolin with a multivalent pseudopeptide delays development of spontaneous melanoma in RET transgenic mice
Q33980633Targeting surface nucleolin with multivalent HB-19 and related Nucant pseudopeptides results in distinct inhibitory mechanisms depending on the malignant tumor cell type
Q54077957The nuclear translocation of endostatin is mediated by its receptor nucleolin in endothelial cells.
Q39232685The pseudopeptide HB-19 binds to cell surface nucleolin and inhibits angiogenesis
Q37968531Transformation of a chronic myeloproliferative neoplasm to acute myelogenous leukemia: does anything work?
Q37098900Urokinase-type Plasminogen Activator (uPA) Promotes Angiogenesis by Attenuating Proline-rich Homeodomain Protein (PRH) Transcription Factor Activity and De-repressing Vascular Endothelial Growth Factor (VEGF) Receptor Expression
Q35067747Urokinase-type plasminogen activator (uPA) induces pulmonary microvascular endothelial permeability through low density lipoprotein receptor-related protein (LRP)-dependent activation of endothelial nitric-oxide synthase
Q41973656Urokinase-type plasminogen activator inhibits efferocytosis of neutrophils

Search more.