Structure and function of the plasminogen/plasmin system

scientific article published on 01 April 2005

Structure and function of the plasminogen/plasmin system is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1160/TH04-12-0842
P698PubMed publication ID15841308

P50authorFrancis J CastellinoQ96229305
Victoria PloplisQ105826433
P433issue4
P304page(s)647-654
P577publication date2005-04-01
P1433published inThrombosis and HaemostasisQ15724413
P1476titleStructure and function of the plasminogen/plasmin system
P478volume93

Reverse relations

cites work (P2860)
Q61448811A Perspective of Coagulation Dysfunction in Multiple Sclerosis and in Experimental Allergic Encephalomyelitis
Q34808641A competitive hexapeptide inhibitor of annexin A2 prevents hypoxia-induced angiogenic events
Q90231776A critical role for plasminogen in inflammation
Q35559411A new class of orthosteric uPAR·uPA small-molecule antagonists are allosteric inhibitors of the uPAR·vitronectin interaction
Q80228171A new role for NF-kappaB in angiogenesis inhibition
Q82637377A new series of the SMTP plasminogen modulator with a phenylglycine-based side chain
Q83914923A new series of the SMTP plasminogen modulators with a phenylamine-based side chain
Q46635176A study of cutaneous lesions caused by Leishmania mexicana in plasminogen-deficient mice
Q39250587Accelerated fibrinolysis and its propagation on vascular endothelial cells by secreted and retained tPA.
Q42914615Activators and inhibitors of the plasminogen system in Alzheimer's disease.
Q58606295Amyloid beta soluble forms and plasminogen activation system in Alzheimer's disease: Consequences on extracellular maturation of brain-derived neurotrophic factor and therapeutic implications
Q90030308An ATF6-tPA pathway in hepatocytes contributes to systemic fibrinolysis and is repressed by DACH1
Q35169853Analysis of Paracoccidioides secreted proteins reveals fructose 1,6-bisphosphate aldolase as a plasminogen-binding protein
Q39367074Angiogenesis and Proteinases: Influence on Vascular Morphogenesis, Stabilization and Regression
Q33222336Angiostatin inhibits pancreatic cancer cell proliferation and growth in nude mice
Q36337574Bacterial plasminogen receptors utilize host plasminogen system for effective invasion and dissemination
Q38057217Bacterial plasminogen receptors: mediators of a multifaceted relationship.
Q39479495Benzyl isothiocyanate inhibits basal and hepatocyte growth factor-stimulated migration of breast cancer cells
Q58041426Beyond hemostasis: the challenge of treating plasminogen deficiency. A report of three cases
Q38669149Biophysical Mechanisms Mediating Fibrin Fiber Lysis.
Q81962689Blood coagulation and fibrinolysis: mechanisms of thrombosis
Q26781646Breaking boundaries-coagulation and fibrinolysis at the neurovascular interface
Q24337821CCBE1 enhances lymphangiogenesis via A disintegrin and metalloprotease with thrombospondin motifs-3-mediated vascular endothelial growth factor-C activation
Q38055477Cell surface remodeling by plasmin: a new function for an old enzyme
Q55239975Changed Expression of Cytoskeleton Proteins During Lung Injury in a Mouse Model of Streptococcus pneumoniae Infection.
Q36480477Curli biogenesis and function
Q57285296Curli-Containing Enteric Biofilms Inside and Out: Matrix Composition, Immune Recognition, and Disease Implications
Q35887881Data supporting the structural and functional characterization of Thrombin-Activatable Fibrinolysis Inhibitor in breast cancer
Q39067705Deciphering Key Residues Involved in the Virulence-promoting Interactions between Streptococcus pneumoniae and Human Plasminogen
Q35079577Decoy plasminogen receptor containing a selective Kunitz-inhibitory domain.
Q35883913Direct Host Plasminogen Binding to Bacterial Surface M-protein in Pattern D Strains of Streptococcus pyogenes Is Required for Activation by Its Natural Coinherited SK2b Protein
Q27644557Discovery of the Fibrinolysis Inhibitor AZD6564, Acting via Interference of a Protein–Protein Interaction
Q34413457Disease manifestations and pathogenic mechanisms of Group A Streptococcus
Q36080505Dissecting mannose 6-phosphate-insulin-like growth factor 2 receptor complexes that control activation and uptake of plasminogen in cells
Q37409534Early effects of paroxysmal atrial fibrillation on plasma markers of fibrinolysis
Q33759211Effects on human plasminogen conformation and activation rate caused by interaction with VEK-30, a peptide derived from the group A streptococcal M-like protein (PAM).
Q28476949Eimeria species and genetic background influence the serum protein profile of broilers with coccidiosis
Q86450783Elevated plasminogen activator inhibitor type-1 (PAI-1) as contributing factor in pathogenesis of hypercoagulable state in antiphospholipid syndrome
Q35586122Endogenously generated plasmin at the vascular wall injury site amplifies lysine binding site-dependent plasminogen accumulation in microthrombi
Q35042660Engineering streptokinase for generation of active site-labeled plasminogen analogs
Q34324817Enhanced venous thrombus resolution in plasminogen activator inhibitor type-2 deficient mice
Q34975047Enolase: a key player in the metabolism and a probable virulence factor of trypanosomatid parasites-perspectives for its use as a therapeutic target.
Q88576022Excessive Plasmin Compromises Hepatic Sinusoidal Vascular Integrity After Acetaminophen Overdose
Q38456535Exploitation of plasmin(ogen) by bacterial pathogens of veterinary significance
Q33244333Expression of angiostatin cDNA in human gallbladder carcinoma cell line GBC-SD and its effect on endothelial proliferation and growth
Q52606339Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics.
Q64937348Fibrinolysis and Inflammation in Venous Thrombus Resolution.
Q91763569Fibrinolysis protease receptors promote activation of astrocytes to express pro-inflammatory cytokines
Q38269342From plasminogen to plasmin: role of plasminogen receptors in human cancer.
Q30372842Genetically determined proteolytic cleavage modulates alpha7beta1 integrin function.
Q37100544How is plasminogen/plasmin system contributing to regulate sperm entry into the oocyte?
Q41928116Human monocyte-derived dendritic cells exposed to hyperthermia show a distinct gene expression profile and selective upregulation of IGFBP6.
Q33822542Impaired fibrinolysis in the antiphospholipid syndrome
Q42422328Intravitreal autologous plasmin as a therapeutic modality for diffuse diabetic macular edema
Q50716839Lack of plasminogen leads to milk stasis and premature mammary gland involution during lactation.
Q91793774Ligneous Periodontitis in a Patient with Type 1 Plasminogen Deficiency: A Case Report and Review of the Literature
Q48188580Markers of inflammation and fibrinolysis in relation to outcome after surgery for lumbar disc herniation. A prospective study on 177 patients
Q24337459Melanotransferrin stimulates t-PA-dependent activation of plasminogen in endothelial cells leading to cell detachment
Q34510846Mice deficient in urokinase-type plasminogen activator have delayed healing of tympanic membrane perforations
Q91729291Molecular characterization of a Trichinella spiralis enolase and its interaction with the host's plasminogen
Q35164287Monoclonal antibodies detect receptor-induced binding sites in Glu-plasminogen
Q99418171Multi-omic studies on missense PLG variants in families with otitis media
Q37088045NF-kappa B: a new player in angiostatic therapy
Q37981959New functions of the fibrinolytic system in bone marrow cell-derived angiogenesis
Q33768031New insights into the role of Plg-RKT in macrophage recruitment
Q37356686New insights into the role of brain-derived neurotrophic factor in synaptic plasticity
Q37115034Novel actions of tissue-type plasminogen activator in chronic kidney disease
Q30482426Nuclear translocation of urokinase-type plasminogen activator
Q91676502Numerous Fasciola plasminogen-binding proteins may underlie blood-brain barrier leakage and explain neurological disorder complexity and heterogeneity in the acute and chronic phases of human fascioliasis
Q61446738Origin and diversification of the plasminogen activation system among chordates
Q36940906Oxidative stress, plasminogen activator inhibitor 1, and lung fibrosis
Q35905628Oxidized phospholipids are present on plasminogen, affect fibrinolysis, and increase following acute myocardial infarction
Q34119378Paracoccidioides brasiliensis enolase is a surface protein that binds plasminogen and mediates interaction of yeast forms with host cells
Q38704015Peptides with 6-Aminohexanoic Acid: Synthesis and Evaluation as Plasmin Inhibitors
Q35032037Photonic activation of plasminogen induced by low dose UVB.
Q41174665Physiologic variations in blood plasminogen levels affect outcomes after acute cerebral thromboembolism in mice: a pathophysiologic role for microvascular thrombosis
Q90058442Plasmin improves oedematous blood-gas barrier by cleaving epithelial sodium channels
Q42124151Plasmin is essential in preventing periodontitis in mice
Q89776548Plasmin-mediated proteolysis of human factor IXa in the presence of calcium/phospholipid: Conversion of procoagulant factor IXa to a fibrinolytic enhancer
Q33884423Plasminogen Tochigi mice exhibit phenotypes similar to wild-type mice under experimental thrombotic conditions
Q90606599Plasminogen is a master regulator and a potential drug candidate for the healing of radiation wounds
Q36013653Plasminogen is an important regulator in the pathogenesis of a murine model of asthma
Q46947348Plasminogen potentiates thrombin cytotoxicity and contributes to pathology of intracerebral hemorrhage in rats
Q37609916Plasminogen receptors: the first quarter century
Q50102258Plasminogen replacement therapy for the treatment of children and adults with congenital plasminogen deficiency
Q34467715Platelets contain tissue factor pathway inhibitor-2 derived from megakaryocytes and inhibits fibrinolysis
Q35783075Porphyromonas gingivalis-derived RgpA-Kgp Complex Activates the Macrophage Urokinase Plasminogen Activator System: IMPLICATIONS FOR PERIODONTITIS
Q42683497Postlactational involution biomarkers plasminogen and phospho-STAT3 are linked with active age-related lobular involution.
Q33758094Probing binding and cellular activity of pyrrolidinone and piperidinone small molecules targeting the urokinase receptor
Q36949037Prothrombotic effects of thrombolytic therapy in a rat (Rattus norvegicus) model of venous thrombolysis
Q42166965Recombinant plasminogen activator inhibitor-1 inhibits intimal hyperplasia
Q33480978Reduction of canine plasminogen leads to an expanded molecule which precipitates
Q34562488Regulation of MMP2 and MMP9 metalloproteinases by FSH and growth factors in bovine granulosa cells
Q37660895Regulation of cell signalling by uPAR.
Q88739316Regulation of plasminogen activation on cell surfaces and fibrin
Q35142158Regulation of proteinases during mouse peri-implantation development: urokinase-type plasminogen activator expression and cross talk with matrix metalloproteinase 9
Q27692619Regulatory systems in bone marrow for hematopoietic stem/progenitor cells mobilization and homing.
Q24293140Residues essential for plasminogen binding by the cation-independent mannose 6-phosphate receptor
Q37189305Revisiting the biological roles of PAI2 (SERPINB2) in cancer
Q99565518Roles of fibrinolytic factors in the alterations in bone marrow hematopoietic stem/progenitor cells during bone repair
Q41958435SMTP (Stachybotrys microspora triprenyl phenol) enhances clot clearance in a pulmonary embolism model in rats
Q82261993SPARC-derived protease substrates to enhance the plasmin sensitivity of molecularly engineered PEG hydrogels
Q37394744Sculpting the blank slate: how fibrin's support of vascularization can inspire biomaterial design
Q36003719Streptococcus uberis plasminogen activator (SUPA) activates human plasminogen through novel species-specific and fibrin-targeted mechanisms
Q92277771Structural Biology and Protein Engineering of Thrombolytics
Q41923457Support vector machine (SVM) based multiclass prediction with basic statistical analysis of plasminogen activators
Q34163191Targeted thrombolysis strategies for neuroprotective effect
Q37695366That's my story, and I'm sticking to it--an update on B. burgdorferi adhesins
Q26741286The Expanding Landscape of Moonlighting Proteins in Yeasts
Q64076093The Long Pentraxin PTX3 as a Link Between Innate Immunity, Tissue Remodeling, and Cancer
Q38927516The Opportunity of Precision Medicine for Breast Cancer With Context-Sensitive Tumor Suppressor Maspin.
Q37401343The Prognostic Significance of Soluble Urokinase Plasminogen Activator Receptor in Acute Myeloid Leukemia
Q35500642The Tissue Fibrinolytic System Contributes to the Induction of Macrophage Function and CCL3 during Bone Repair in Mice
Q49817123The clinical value of soluble urokinase plasminogen activation receptor in febrile neutropenic patients with hematological malignancies after chemotherapy
Q38803641The evolution of recombinant thrombolytics: Current status and future directions
Q34249848The generation and characterization of mice expressing a plasmin-inactivating active site mutation
Q37817023The plasmin-antiplasmin system: structural and functional aspects
Q36228900The plasminogen activator system modulates sympathetic nerve function.
Q58698635The plasminogen binding protein PbsP is required for brain invasion by hypervirulent CC17 Group B streptococci
Q104459005The plasminogen receptor, Plg-RKT, plays a role in inflammation and fibrinolysis during cutaneous wound healing in mice
Q38057219The plasminogen system in regulating stem cell mobilization
Q38202723The porcine innate immune system: an update
Q90171163Therapeutics targeting the fibrinolytic system
Q38099731Three are better than one: plasminogen receptors as cancer theranostic targets.
Q28246124Thrombin and vascular inflammation
Q37419812Thrombolytic therapy for deep vein thrombosis: potential application of plasmin
Q34202920Tissue plasminogen activator and plasminogen activator inhibitor 1 contribute to sonic hedgehog-induced in vitro cerebral angiogenesis
Q92059092Tissue-type plasminogen activator-primed human iPSC-derived neural progenitor cells promote motor recovery after severe spinal cord injury
Q51731919Total urokinase-type plasminogen activator (uPA) levels in seminal plasma are associated with positive assisted reproductive technology outcomes.
Q33691725Tranexamic acid-induced ligneous conjunctivitis with renal failure showed reversible hypoplasminogenaemia
Q36832462Urinary angiostatin--a novel putative marker of renal pathology chronicity in lupus nephritis
Q39736356Urokinase-type plasminogen activator induces BV-2 microglial cell migration through activation of matrix metalloproteinase-9.
Q90258614tPA promotes the proliferation of lung fibroblasts and activates the Wnt/β-catenin signaling pathway in idiopathic pulmonary fibrosis

Search more.