| scholarly article | Q13442814 |
| review article | Q7318358 |
| P50 | author | Kullervo Hynynen | Q31088142 |
| P2860 | cites work | Blood-brain barrier disruption induced by focused ultrasound and circulating preformed microbubbles appears to be characterized by the mechanical index | Q24648329 |
| The status of gene therapy for brain tumors | Q24651009 | ||
| Observation on the integrity of the blood-brain barrier after microbubble destruction by diagnostic transcranial color-coded sonography | Q43947964 | ||
| A numerical study of transcranial focused ultrasound beam propagation at low frequency | Q46426104 | ||
| MRI-guided targeted blood-brain barrier disruption with focused ultrasound: histological findings in rabbits | Q46802417 | ||
| Osmotic blood-brain barrier disruption chemotherapy for diffuse pontine gliomas | Q46825473 | ||
| In vivo transcranial brain surgery with an ultrasonic time reversal mirror | Q48138470 | ||
| Quantitative evaluation of focused ultrasound with a contrast agent on blood-brain barrier disruption. | Q48140436 | ||
| Treatment for patients with cerebral metastases | Q48149273 | ||
| Blood-brain barrier disruption in experimental focal ischemia: comparison between in vivo MRI and immunocytochemistry | Q48216905 | ||
| Central nervous system metastases in women who receive trastuzumab-based therapy for metastatic breast carcinoma | Q48291216 | ||
| Noninvasive, transcranial and localized opening of the blood-brain barrier using focused ultrasound in mice | Q48327685 | ||
| The threshold for brain damage in rabbits induced by bursts of ultrasound in the presence of an ultrasound contrast agent (Optison®) | Q48330046 | ||
| Ultrasound augmentation of central nervous system tumor therapy | Q48481658 | ||
| Demonstration of potential noninvasive ultrasound brain therapy through an intact skull | Q48486462 | ||
| Multiphoton imaging of ultrasound/Optison mediated cerebrovascular effects in vivo | Q48548605 | ||
| Blood-brain barrier disruption by low-frequency ultrasound | Q48563571 | ||
| High-intensity focused ultrasound selectively disrupts the blood-brain barrier in vivo | Q48621051 | ||
| Targeted disruption of the blood-brain barrier with focused ultrasound: association with cavitation activity | Q48655725 | ||
| Treatment of malignant brain tumors with focused ultrasound hyperthermia and radiation: results of a phase I trial | Q48718369 | ||
| Cellular mechanisms of the blood-brain barrier opening induced by ultrasound in presence of microbubbles | Q50250294 | ||
| 500-element ultrasound phased array system for noninvasive focal surgery of the brain: a preliminary rabbit study with ex vivo human skulls. | Q50250325 | ||
| MRI investigation of the threshold for thermally induced blood-brain barrier disruption and brain tissue damage in the rabbit brain | Q50250371 | ||
| Histologic effects of high intensity pulsed ultrasound exposure with subharmonic emission in rabbit brain in vivo | Q50253319 | ||
| Optison (FS069) disrupts the blood-brain barrier in rats. | Q50509258 | ||
| P32 uptake by normal and ultrasonically irradiated brain tissue from cerebrospinal fluid. | Q51314462 | ||
| Safety and efficacy of a multicenter study using intraarterial chemotherapy in conjunction with osmotic opening of the blood-brain barrier for the treatment of patients with malignant brain tumors. | Q51421065 | ||
| Fundamental neurological research and human neurosurgery using intense ultrasound | Q78842280 | ||
| Enhanced ultrasound transmission through the human skull using shear mode conversion | Q79855437 | ||
| Acoustic radiation force in vivo: a mechanism to assist targeting of microbubbles | Q28138819 | ||
| Local and reversible blood-brain barrier disruption by noninvasive focused ultrasound at frequencies suitable for trans-skull sonications | Q28297458 | ||
| Acoustic cavitation: a possible consequence of biomedical uses of ultrasound | Q30486724 | ||
| Effect of focused ultrasound applied with an ultrasound contrast agent on the tight junctional integrity of the brain microvascular endothelium | Q30488665 | ||
| Effects of acoustic parameters and ultrasound contrast agent dose on focused-ultrasound induced blood-brain barrier disruption | Q30489416 | ||
| Use of ultrasound pulses combined with Definity for targeted blood-brain barrier disruption: a feasibility study | Q30496586 | ||
| Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruption | Q30500905 | ||
| Improved selective, simple, and contrast staining of acidophilic neurons with vanadium acid fuchsin | Q30860397 | ||
| Noninvasive MR imaging-guided focal opening of the blood-brain barrier in rabbits | Q33954300 | ||
| A non-invasive method for focusing ultrasound through the human skull | Q33959339 | ||
| Experimental demonstration of noninvasive transskull adaptive focusing based on prior computed tomography scans | Q33964036 | ||
| Ultrasonically produced changes in the blood-brain barrier. | Q33969350 | ||
| Progress and problems in the neurological applications of focused ultrasound | Q33970135 | ||
| Targeted delivery of antibodies through the blood-brain barrier by MRI-guided focused ultrasound | Q33992793 | ||
| Brain arterioles show more active vesicular transport of blood-borne tracer molecules than capillaries and venules after focused ultrasound-evoked opening of the blood-brain barrier | Q33999429 | ||
| Targeted delivery of doxorubicin to the rat brain at therapeutic levels using MRI-guided focused ultrasound | Q34003611 | ||
| Clinical trials of single-agent trastuzumab (Herceptin). | Q34069297 | ||
| Focal disruption of the blood-brain barrier due to 260-kHz ultrasound bursts: a method for molecular imaging and targeted drug delivery | Q34564681 | ||
| Drug and gene delivery to the brain: the vascular route | Q35003855 | ||
| Morphology and molecular properties of cellular components of normal cerebral vessels | Q35213058 | ||
| Therapeutic applications of lipid-coated microbubbles. | Q35756608 | ||
| Incidence of cerebral metastases in patients treated with trastuzumab for metastatic breast cancer. | Q35842144 | ||
| Studies on the in vivo disposition of adriamycin in human tumours which exhibit different responses to the drug | Q36027193 | ||
| Clinical applications of focused ultrasound-the brain. | Q36853097 | ||
| The physiology of the blood-brain barrier. | Q37990987 | ||
| Effect of heat preconditioning on the uptake and permeability of R123 in brain microvessel endothelial cells during mild heat treatment | Q40527528 | ||
| Outwitting the blood-brain barrier for therapeutic purposes: osmotic opening and other means | Q40859254 | ||
| Transporting therapeutics across the blood-brain barrier | Q41105360 | ||
| Ultrasound and the blood-brain barrier. | Q42477510 | ||
| P433 | issue | 10 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1209-1217 | |
| P577 | publication date | 2008-04-06 | |
| P1433 | published in | Advanced Drug Delivery Reviews | Q2825362 |
| P1476 | title | Ultrasound for drug and gene delivery to the brain | |
| P478 | volume | 60 |
| Q39139224 | Advances in Molecular Imaging of Locally Delivered Targeted Therapeutics for Central Nervous System Tumors. |
| Q47556738 | Antidepressant effects of focused ultrasound induced blood-brain-barrier opening. |
| Q58600222 | Applications of Focused Ultrasound in Cerebrovascular Diseases and Brain Tumors |
| Q53405050 | Association schemes perspective of microbubble cluster in ultrasonic fields. |
| Q39233422 | Brain-Targeted Polymers for Gene Delivery in the Treatment of Brain Diseases |
| Q30416852 | Calibration of the 1-MHz Sonitron ultrasound system. |
| Q27006059 | Can ultrasound enable efficient intracellular uptake of molecules? A retrospective literature review and analysis |
| Q30476829 | Cavitation properties of block copolymer stabilized phase-shift nanoemulsions used as drug carriers |
| Q30475367 | Contrast agent kinetics in the rabbit brain during exposure to therapeutic ultrasound |
| Q87419475 | Contribution of inertial cavitation in the enhancement of in vitro transscleral drug delivery |
| Q47984087 | Controlled release of liposome-encapsulated temozolomide for brain tumour treatment by convection-enhanced delivery. |
| Q38071680 | Current options for drug delivery to the spinal cord |
| Q30477374 | Delivery of molecules into cells using carbon nanoparticles activated by femtosecond laser pulses |
| Q30472420 | Doxorubicin as a Molecular Nanotheranostic Agent: Effect of Doxorubicin Encapsulation in Micelles or Nanoemulsions on the Ultrasound-Mediated Intracellular Delivery and Nuclear Trafficking |
| Q44960883 | Effect of 12-oxochenodeoxycholate on the pharmacokinetics and pharmacodynamics of morphine 6-glucuronide in Wistar rats |
| Q45879620 | Effective gene transfer into central nervous system following ultrasound-microbubbles-induced opening of the blood-brain barrier |
| Q39156541 | Effects of biophysical parameters in enhancing radiation responses of prostate tumors with ultrasound-stimulated microbubbles |
| Q48101075 | Effects of combining low frequency ultrasound irradiation with papaverine on the permeability of the blood–tumor barrier |
| Q92946138 | Encapsulation and Ultrasound-Triggered Release of G-Quadruplex DNA in Multilayer Hydrogel Microcapsules |
| Q30401360 | Enhancement of Blood-Brain Barrier Permeability and Delivery of Antisense Oligonucleotides or Plasmid DNA to the Brain by the Combination of Bubble Liposomes and High-Intensity Focused Ultrasound |
| Q48175287 | Evaluation of dose distribution of molecular delivery after blood-brain barrier disruption by focused ultrasound with treatment planning |
| Q93031515 | Fast qualitative two-dimensional mapping of ultrasound fields with acoustic cavitation-enhanced ultrasound imaging |
| Q98224395 | Focused Ultrasound for Noninvasive, Focal Pharmacologic Neurointervention |
| Q30429684 | Focused ultrasound and microbubbles for enhanced extravasation |
| Q30434475 | Focused ultrasound disruption of the blood-brain barrier: a new frontier for therapeutic delivery in molecular neurooncology |
| Q30386804 | Focused ultrasound enhanced molecular imaging and gene therapy for multifusion reporter gene in glioma-bearing rat model |
| Q91930510 | High-intensity focused ultrasound-induced mechanochemical transduction in synthetic elastomers |
| Q41677368 | Imaging grafted cells with [18F]FHBG using an optimized HSV1-TK mammalian expression vector in a brain injury rodent model. |
| Q30476124 | Improved algorithm for estimation of attenuation along propagation path using backscattered echoes from multiple sources |
| Q26861530 | Improving the performance of phase-change perfluorocarbon droplets for medical ultrasonography: current progress, challenges, and prospects |
| Q30395756 | In Vivo application and localization of transcranial focused ultrasound using dual-mode ultrasound arrays |
| Q30361413 | Increasing of Blood-Brain Tumor Barrier Permeability through Transcellular and Paracellular Pathways by Microbubble-Enhanced Diagnostic Ultrasound in a C6 Glioma Model. |
| Q43260643 | Interaction of a high-order Bessel beam with a submerged spherical ultrasound contrast agent shell - Scattering theory |
| Q30476853 | Intracellular delivery and calcium transients generated in sonoporation facilitated by microbubbles |
| Q38975707 | Magnetic field enhanced convective diffusion of iron oxide nanoparticles in an osmotically disrupted cell culture model of the blood-brain barrier |
| Q47987226 | Mathematical Modelling of Convection Enhanced Delivery of Carmustine and Paclitaxel for Brain Tumour Therapy |
| Q47105144 | Methods of Generating Submicrometer Phase-Shift Perfluorocarbon Droplets for Applications in Medical Ultrasonography |
| Q28766660 | Methods, potentials, and limitations of gene delivery to regenerate central nervous system cells |
| Q38244304 | Micro- and nanotechnologies for intracellular delivery |
| Q43163130 | Microbubble mediated sonoporation of cells in suspension: clonogenic viability and influence of molecular size on uptake |
| Q38685760 | Modulators of microglia: a patent review |
| Q30441159 | Multi-modality safety assessment of blood-brain barrier opening using focused ultrasound and definity microbubbles: a short-term study. |
| Q52586784 | Multi-resolution simulation of focused ultrasound propagation through ovine skull from a single-element transducer. |
| Q38686370 | Nanotechnology based theranostic approaches in Alzheimer's disease management: Current status and future perspective. |
| Q26801485 | Neurosurgical Techniques for Disruption of the Blood-Brain Barrier for Glioblastoma Treatment |
| Q31048620 | Noninvasive and targeted delivery of therapeutics to the brain using focused ultrasound |
| Q37855817 | Novel and emerging strategies in drug delivery for overcoming the blood-brain barrier |
| Q35064473 | Novel central nervous system drug delivery systems |
| Q59811145 | Opening the Blood-Brain Barrier and Improving the Efficacy of Temozolomide Treatments of Glioblastoma Using Pulsed, Focused Ultrasound with a Microbubble Contrast Agent |
| Q30469311 | Over-pressure suppresses ultrasonic-induced drug uptake |
| Q33618320 | Overcoming Biological Barriers with Ultrasound |
| Q38401187 | Parameters and characteristics governing cellular internalization and trans-barrier trafficking of nanostructures |
| Q47347678 | Passive acoustic mapping of cavitation using eigenspace-based robust Capon beamformer in ultrasound therapy |
| Q30408121 | Passive cavitation detection during pulsed HIFU exposures of ex vivo tissues and in vivo mouse pancreatic tumors |
| Q30478402 | Passive cavitation imaging with ultrasound arrays |
| Q92085385 | Passive cavitation mapping using dual apodization with cross-correlation in ultrasound therapy monitoring |
| Q28541576 | Pharmacokinetic changes induced by focused ultrasound in glioma-bearing rats as measured by dynamic contrast-enhanced MRI |
| Q51164308 | Phase transitions of perfluorocarbon nanoemulsion induced with ultrasound: a mathematical model. |
| Q30466278 | Phase-shift, stimuli-responsive drug carriers for targeted delivery |
| Q30450131 | Phase-shift, stimuli-responsive perfluorocarbon nanodroplets for drug delivery to cancer |
| Q39174128 | Physical constraints on the non-dimensional absorption coefficients of compressional and shear waves for viscoelastic cylinders |
| Q33646512 | Potential Pathways for CNS Drug Delivery Across the Blood-Cerebrospinal Fluid Barrier |
| Q35967411 | Preclinical approaches to study the biology and treatment of brain metastases |
| Q38001396 | Principles and emerging applications of nanomagnetic materials in medicine |
| Q26778701 | Promising approaches to circumvent the blood-brain barrier: progress, pitfalls and clinical prospects in brain cancer |
| Q30475028 | Protein expression of mesenchymal stem cells after transfection of pcDNA3.1⁻-hVEGF₁₆₅ by ultrasound-targeted microbubble destruction |
| Q27347648 | Pulsed High-Intensity Focused Ultrasound Enhances Delivery of Doxorubicin in a Preclinical Model of Pancreatic Cancer. |
| Q48365401 | Pulsed-wave low-dose ultrasound hyperthermia selectively enhances nanodrug delivery and improves antitumor efficacy for brain metastasis of breast cancer. |
| Q92322332 | Pyrosequencing versus methylation-specific PCR for assessment of MGMT methylation in tumor and blood samples of glioblastoma patients |
| Q30436709 | Recent advances in molecular, multimodal and theranostic ultrasound imaging |
| Q30399021 | Remote spatiotemporally controlled and biologically selective permeabilization of blood-brain barrier |
| Q84218639 | Safety and bio-effects of ultrasound contrast agents |
| Q45858068 | Sonoporation, drug delivery, and gene therapy |
| Q38610113 | Strategies to target drugs to gliomas and CNS metastases of solid tumors |
| Q42808770 | Structural and permeability sensitivity of cells to low intensity ultrasound: Infrared and fluorescence evidence in vitro |
| Q27010580 | Targeted delivery of antibody-based therapeutic and imaging agents to CNS tumors: crossing the blood-brain barrier divide |
| Q30472787 | Targeted delivery of neural stem cells to the brain using MRI-guided focused ultrasound to disrupt the blood-brain barrier |
| Q30474781 | Targeted drug delivery across the blood-brain barrier using ultrasound technique |
| Q48304889 | The breakup of intravascular microbubbles and its impact on the endothelium |
| Q90107233 | Therapeutic Potentials of Localized Blood-Brain Barrier Disruption by Noninvasive Transcranial Focused Ultrasound: A Technical Review |
| Q30354625 | Transcranial pulsed ultrasound facilitates brain uptake of laronidase in enzyme replacement therapy for Mucopolysaccharidosis type I disease |
| Q43278040 | Ultrasonic focusing through the ribs using the DORT method. |
| Q30477363 | Ultrasonic nanotherapy of pancreatic cancer: lessons from ultrasound imaging |
| Q30429594 | Ultrasound and microbubble guided drug delivery: mechanistic understanding and clinical implications |
| Q30478731 | Ultrasound-enhanced drug transport and distribution in the brain |
| Q30425538 | Ultrasound-enhanced protective effect of tetramethylpyrazine against cerebral ischemia/reperfusion injury |
| Q38012536 | Ultrasound-induced cell permeabilisation and hyperthermia: strategies for local delivery of compounds with intracellular mode of action |
| Q47862334 | Ultrasound-mediated delivery and distribution of polymeric nanoparticles in the normal brain parenchyma of a metastatic brain tumour model |
| Q26827216 | Ultrasound-mediated oncolytic virus delivery and uptake for increased therapeutic efficacy: state of art. |
| Q30465710 | Ultrasound-mediated tumor imaging and nanotherapy using drug loaded, block copolymer stabilized perfluorocarbon nanoemulsions |
| Q90022589 | Ultrasound-responsive droplets for therapy: A review |
| Q42174709 | Understanding Acoustic Cavitation Initiation by Porous Nanoparticles: Toward Nanoscale Agents for Ultrasound Imaging and Therapy. |
| Q30370707 | Vaporization dynamics of volatile perfluorocarbon droplets: a theoretical model and in vitro validation |
| Q42256825 | Variation of High-Intensity Therapeutic Ultrasound (HITU) Pressure Field Characterization: Effects of Hydrophone Choice, Nonlinearity, Spatial Averaging and Complex Deconvolution |
| Q36085336 | dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis |
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