Neurosteroid regulation of GABA(A) receptors: Focus on the alpha4 and delta subunits

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Neurosteroid regulation of GABA(A) receptors: Focus on the alpha4 and delta subunits is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.PHARMTHERA.2007.03.008
P8608Fatcat IDrelease_opwcfsqrofdxnf6a27au67uikq
P932PMC publication ID2657726
P698PubMed publication ID17512983
P5875ResearchGate publication ID6319497

P50authorSheryl S. SmithQ43243561
P2093author name stringHui Shen
Qi Hua Gong
Xiangping Zhou
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3alpha-hydroxy-5alpha-pregnan-20-one exposure reduces GABA(A) receptor alpha4 subunit mRNA levels.Q51371265
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Gonadal steroids regulate GABAA receptor subunit mRNA expression in NT2-N neuronsQ40401351
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Neurosteroids shift partial agonist activation of GABA(A) receptor channels from low- to high-efficacy gating patterns.Q40611808
Oxytocin regulates neurosteroid modulation of GABA(A) receptors in supraoptic nucleus around parturition.Q40671885
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Properties of recombinant gamma-aminobutyric acid A receptor isoforms containing the alpha 5 subunit subtype.Q41189242
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GABA induces activity dependent delayed-onset uncoupling of GABA/benzodiazepine site interactions in neocortical neurons.Q42476389
Chronic neurosteroid treatment produces functional heterologous uncoupling at the gamma-aminobutyric acid type A/benzodiazepine receptor complex in mammalian cortical neurons.Q42484258
Brain-derived neurotrophic factor (BDNF)-induced synthesis of early growth response factor 3 (Egr3) controls the levels of type A GABA receptor alpha 4 subunits in hippocampal neuronsQ42499572
Withdrawal from 3alpha-OH-5alpha-pregnan-20-One using a pseudopregnancy model alters the kinetics of hippocampal GABAA-gated current and increases the GABAA receptor alpha4 subunit in association with increased anxiety.Q42541290
Estrous cycle and sex differences in performance on anxiety tasks coincide with increases in hippocampal progesterone and 3alpha,5alpha-THP.Q42641575
Changes in progesterone metabolites in the hippocampus can modulate open field and forced swim test behavior of proestrous ratsQ42674934
Steroid anesthetics and naturally occurring analogs modulate the gamma-aminobutyric acid receptor complex at a site distinct from barbituratesQ43468628
Regulation of uterine gamma-aminobutyric acid(A) receptor subunit expression throughout pregnancyQ43584820
Adaptive regulation of neuronal excitability by a voltage-independent potassium conductanceQ43601149
Neurosteroid withdrawal model of perimenstrual catamenial epilepsy.Q43665513
Enhanced anticonvulsant activity of neuroactive steroids in a rat model of catamenial epilepsy.Q43665517
Distinct signal transduction pathways for GABA-induced GABA(A) receptor down-regulation and uncoupling in neuronal culture: a role for voltage-gated calcium channelsQ43735220
Menstrual cycle interval and ovulation in women with localization-related epilepsyQ43820153
Changes in GABA(A) receptor gene expression induced by withdrawal of, but not by long-term exposure to, zaleplon or zolpidemQ43862488
Receptors with different affinities mediate phasic and tonic GABA(A) conductances in hippocampal neurons.Q43990181
Allopregnanolone levels and symptom improvement in severe premenstrual syndromeQ44156727
Alpha1 and alpha6 subunits specify distinct desensitization, deactivation and neurosteroid modulation of GABA(A) receptors containing the delta subunitQ44169931
The influence of subunit composition on the interaction of neurosteroids with GABA(A) receptorsQ44169994
Withdrawal from chronic intermittent ethanol treatment changes subunit composition, reduces synaptic function, and decreases behavioral responses to positive allosteric modulators of GABAA receptorsQ44253602
Excitatory actions of GABA in the cortex.Q44290626
Progesterone, neurosteroids, and the hormonal basis of catamenial epilepsyQ44325273
Anxiogenic effects of neurosteroid exposure: sex differences and altered GABAA receptor pharmacology in adult ratsQ44329196
Vigabatrin induces tonic inhibition via GABA transporter reversal without increasing vesicular GABA release.Q44336888
Reduced inhibition and sensitivity to neurosteroids in hippocampus of mice lacking the GABA(A) receptor delta subunitQ44408498
Chronic ethanol consumption enhances internalization of alpha1 subunit-containing GABAA receptors in cerebral cortex.Q44512257
Abnormal luteal phase excitability of the motor cortex in women with premenstrual syndromeQ44598183
The contraceptive agent Provera enhances GABA(A) receptor-mediated inhibitory neurotransmission in the rat hippocampus: evidence for endogenous neurosteroids?Q44645630
Altered pharmacology of synaptic and extrasynaptic GABAA receptors on CA1 hippocampal neurons is consistent with subunit changes in a model of alcohol withdrawal and dependenceQ44883361
Panic disorder in menopause: a case control studyQ44917275
Transcriptional regulation of the mouse gene encoding the alpha-4 subunit of the GABAA receptorQ44987410
Effects of PhD examination stress on allopregnanolone and cortisol plasma levels and peripheral benzodiazepine receptor densityQ45003478
P433issue1
P304page(s)58-76
P577publication date2007-04-21
P1433published inPharmacology & TherapeuticsQ3378596
P1476titleNeurosteroid regulation of GABA(A) receptors: Focus on the alpha4 and delta subunits
P478volume116

Reverse relations

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