| scholarly article | Q13442814 |
| P50 | author | Delia Belelli | Q48580164 |
| P2093 | author name string | Jeremy J Lambert | |
| Keith A Wafford | |||
| Thomas W Rosahl | |||
| Dianne R Peden | |||
| P2860 | cites work | Development of a tonic form of synaptic inhibition in rat cerebellar granule cells resulting from persistent activation of GABAA receptors | Q24530653 |
| The interaction of the general anesthetic etomidate with the gamma-aminobutyric acid type A receptor is influenced by a single amino acid | Q24654417 | ||
| Pharmacological characterization of a novel cell line expressing human alpha(4)beta(3)delta GABA(A) receptors | Q24673026 | ||
| Neurosteroids: endogenous regulators of the GABA(A) receptor | Q28256904 | ||
| Variations on an inhibitory theme: phasic and tonic activation of GABA(A) receptors | Q29616809 | ||
| On the cellular and network bases of epileptic seizures. | Q31963797 | ||
| Neuroactive steroids reduce neuronal excitability by selectively enhancing tonic inhibition mediated by delta subunit-containing GABAA receptors | Q33717685 | ||
| General anaesthetic action at transmitter-gated inhibitory amino acid receptors | Q33798108 | ||
| Ethanol enhances alpha 4 beta 3 delta and alpha 6 beta 3 delta gamma-aminobutyric acid type A receptors at low concentrations known to affect humans | Q34277701 | ||
| Ovarian cycle-linked changes in GABA(A) receptors mediating tonic inhibition alter seizure susceptibility and anxiety | Q34419058 | ||
| Thalamic circuitry and thalamocortical synchrony | Q35081236 | ||
| The corticothalamic system in sleep | Q35109437 | ||
| Molecular and neuronal substrates for general anaesthetics | Q35868065 | ||
| Diazepam-induced changes in sleep: role of the alpha 1 GABA(A) receptor subtype | Q35949371 | ||
| Sleep, epilepsy and thalamic reticular inhibitory neurons | Q36146227 | ||
| Tonic inhibition in mouse hippocampal CA1 pyramidal neurons is mediated by alpha5 subunit-containing gamma-aminobutyric acid type A receptors | Q37074693 | ||
| Modulation of rhythmic brain activity by diazepam: GABA(A) receptor subtype and state specificity. | Q37074743 | ||
| Selective modulation of tonic and phasic inhibitions in dentate gyrus granule cells | Q40644380 | ||
| Nucleus-specific differences in GABA(A)-receptor-mediated inhibition are enhanced during thalamic development | Q41714103 | ||
| Intact synaptic GABAergic inhibition and altered neurosteroid modulation of thalamic relay neurons in mice lacking delta subunit. | Q42438034 | ||
| GABA(A) receptors: immunocytochemical distribution of 13 subunits in the adult rat brain. | Q42497057 | ||
| Subunit-dependent interaction of the general anaesthetic etomidate with the gamma-aminobutyric acid type A receptor | Q43168431 | ||
| Loss of the major GABA(A) receptor subtype in the brain is not lethal in mice. | Q43594220 | ||
| Receptors with different affinities mediate phasic and tonic GABA(A) conductances in hippocampal neurons. | Q43990181 | ||
| Sleep states and sleep electroencephalographic spectral power in mice lacking the beta 3 subunit of the GABA(A) receptor | Q44207392 | ||
| GABA(A) agonists and partial agonists: THIP (Gaboxadol) as a non-opioid analgesic and a novel type of hypnotic | Q44346867 | ||
| Dynamic GABA(A) receptor subtype-specific modulation of the synchrony and duration of thalamic oscillations. | Q44433373 | ||
| Diazepam-induced changes on sleep and the EEG spectrum in mice: role of the alpha3-GABA(A) receptor subtype | Q44465609 | ||
| Sedation and anesthesia mediated by distinct GABA(A) receptor isoforms. | Q44588647 | ||
| The contraceptive agent Provera enhances GABA(A) receptor-mediated inhibitory neurotransmission in the rat hippocampus: evidence for endogenous neurosteroids? | Q44645630 | ||
| Low ethanol concentrations selectively augment the tonic inhibition mediated by delta subunit-containing GABAA receptors in hippocampal neurons. | Q45072876 | ||
| Toward a unified theory of narcosis: brain imaging evidence for a thalamocortical switch as the neurophysiologic basis of anesthetic-induced unconsciousness. | Q45962033 | ||
| Brain mechanisms of propofol-induced loss of consciousness in humans: a positron emission tomographic study | Q48181125 | ||
| Reciprocal inhibitory connections and network synchrony in the mammalian thalamus | Q48301232 | ||
| The GABAA receptor agonist THIP alters the EEG in waking and sleep of mice | Q48556845 | ||
| Network modulation of a slow intrinsic oscillation of cat thalamocortical neurons implicated in sleep delta waves: cortically induced synchronization and brainstem cholinergic suppression | Q48641576 | ||
| Three types of inhibitory postsynaptic potentials generated by interneurons in the anterior thalamic complex of cat. | Q48651877 | ||
| Sleep and Its Modulation by Drugs That Affect GABA(A) Receptor Function | Q48737070 | ||
| Effect of benzodiazepine hypnotics on all-night sleep EEG spectra | Q49060283 | ||
| Role of GABAA receptors in sleep regulation. Differential effects of muscimol and midazolam on sleep in rats. | Q51567837 | ||
| Pharmacokinetics of the gamma-aminobutyric acid agonist THIP (Gaboxadol) following intramuscular administration to man, with observations in dog | Q71160196 | ||
| The GABAA agonist THIP (gaboxadol) increases non-REM sleep and enhances delta activity in the rat | Q71806435 | ||
| P433 | issue | 50 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 11513-11520 | |
| P577 | publication date | 2005-12-01 | |
| P1433 | published in | Journal of Neuroscience | Q1709864 |
| P1476 | title | Extrasynaptic GABAA receptors of thalamocortical neurons: a molecular target for hypnotics | |
| P478 | volume | 25 |
| Q34207469 | A neuron-glia interaction involving GABA transaminase contributes to sleep loss in sleepless mutants |
| Q36675803 | A study of subunit selectivity, mechanism and site of action of the delta selective compound 2 (DS2) at human recombinant and rodent native GABA(A) receptors |
| Q42976609 | A thalamic sleep tonic |
| Q33883592 | Aberrant GABA(A) receptor-mediated inhibition in cortico-thalamic networks of succinic semialdehyde dehydrogenase deficient mice. |
| Q45417258 | Acting locally but sensing globally: impact of GABAergic synaptic plasticity on phasic and tonic inhibition in the thalamus. |
| Q30439233 | Age-related GABAA receptor changes in rat auditory cortex |
| Q33393899 | Allopregnanolone-induced rise in intracellular calcium in embryonic hippocampal neurons parallels their proliferative potential |
| Q49228452 | Allosteric Modulation of αβδ GABAA Receptors. |
| Q33624043 | Altered localization of the δ subunit of the GABAA receptor in the thalamus of α4 subunit knockout mice |
| Q47865440 | Altered temporal variance and neural synchronization of spontaneous brain activity in anesthesia |
| Q64899064 | Animal Models of PTSD: The Socially Isolated Mouse and the Biomarker Role of Allopregnanolone. |
| Q47822542 | Attenuated benzodiazepine-sensitive tonic GABAA currents of supraoptic magnocellular neuroendocrine cells in 24-h water-deprived rats. |
| Q34017529 | Augmentation of Tonic GABA(A) Inhibition in Absence Epilepsy: Therapeutic Value of Inverse Agonists at Extrasynaptic GABA(A) Receptors |
| Q45387344 | Bicuculline- and neurosteroid-sensitive tonic chloride current in rat hypoglossal motoneurons and atypical dual effect of SR95531. |
| Q48458377 | Changes in expression of the delta subunit of the GABA (A) receptor and in receptor function induced by progesterone exposure and withdrawal. |
| Q57987415 | Chemogenetic Isolation Reveals Synaptic Contribution of δ GABA Receptors in Mouse Dentate Granule Neurons |
| Q46320832 | Chronic intermittent ethanol-induced switch of ethanol actions from extrasynaptic to synaptic hippocampal GABAA receptors. |
| Q60914551 | Clinical Development of Targeted Fragile X Syndrome Treatments: An Industry Perspective |
| Q37319964 | Comparing the discriminative stimulus effects of modulators of GABAA receptors containing α4-δ subunits with those of gaboxadol in rats |
| Q47215880 | Comparison of αβδ and αβγ GABAA receptors: Allosteric modulation and identification of subunit arrangement by site-selective general anesthetics |
| Q47258075 | Competitive Antagonism of Anesthetic Action at the γ-Aminobutyric Acid Type A Receptor by a Novel Etomidate Analog with Low Intrinsic Efficacy. |
| Q48427544 | Deletion of the GABA(A) receptor alpha1 subunit increases tonic GABA(A) receptor current: a role for GABA uptake transporters. |
| Q51970335 | Developmental maturation of synaptic and extrasynaptic GABAA receptors in mouse thalamic ventrobasal neurones. |
| Q41628434 | Developmentally regulated neurosteroid synthesis enhances GABAergic neurotransmission in mouse thalamocortical neurones |
| Q46782245 | Differential tonic GABA conductances in striatal medium spiny neurons |
| Q43137749 | Disinhibition of olfactory bulb granule cells accelerates odour discrimination in mice |
| Q37381812 | Dysfunctional astrocytic and synaptic regulation of hypothalamic glutamatergic transmission in a mouse model of early-life adversity: relevance to neurosteroids and programming of the stress response. |
| Q35311652 | EEG power spectra response to a 4-h phase advance and gaboxadol treatment in 822 men and women |
| Q36729857 | Early postnatal switch in GABAA receptor α-subunits in the reticular thalamic nucleus |
| Q58792105 | Early-life adversity selectively impairs α2-GABA receptor expression in the mouse nucleus accumbens and influences the behavioral effects of cocaine |
| Q36948422 | Effect of gaboxadol on sleep in adult and elderly patients with primary insomnia: results from two randomized, placebo-controlled, 30-night polysomnography studies |
| Q41896998 | Effect of microdialysis perfusion of 4,5,6,7-tetrahydroisoxazolo-[5,4-c]pyridine-3-ol in the perifornical hypothalamus on sleep-wakefulness: role of delta-subunit containing extrasynaptic GABAA receptors |
| Q37177059 | Emerging anti-insomnia drugs: tackling sleeplessness and the quality of wake time |
| Q34778241 | Endogenous GABA levels in the pontine reticular formation are greater during wakefulness than during rapid eye movement sleep |
| Q30395385 | Enhanced GABAA-Mediated Tonic Inhibition in Auditory Thalamus of Rats with Behavioral Evidence of Tinnitus |
| Q46894690 | Enhanced behavioral sensitivity to the competitive GABA agonist, gaboxadol, in transgenic mice over-expressing hippocampal extrasynaptic alpha6beta GABA(A) receptors |
| Q24684762 | Enhanced macroscopic desensitization shapes the response of alpha4 subtype-containing GABAA receptors to synaptic and extrasynaptic GABA |
| Q30493216 | Enhanced tonic GABAA inhibition in typical absence epilepsy. |
| Q36852883 | Epilepsy, E/I Balance and GABA(A) Receptor Plasticity. |
| Q92442153 | Escape From Oblivion: Neural Mechanisms of Emergence From General Anesthesia |
| Q37158840 | Ethanol modulates synaptic and extrasynaptic GABAA receptors in the thalamus |
| Q58617168 | Etomidate Effects on Desensitization and Deactivation of α4β3δ GABA Receptors Inducibly Expressed in HEK293 TetR Cells |
| Q48631976 | Etomidate reduces initiation of backpropagating dendritic action potentials: implications for sensory processing and synaptic plasticity during anesthesia |
| Q35794756 | Etomidate uniquely modulates the desensitization of recombinant α1β3δ GABA(A) receptors |
| Q43218936 | Excitability of cortical neurons depends upon a powerful tonic conductance in inhibitory networks |
| Q28743254 | Extrasynaptic GABA(A) receptors and tonic inhibition in rat auditory thalamus. |
| Q48155809 | Extrasynaptic GABA(A) receptors couple presynaptic activity to postsynaptic inhibition in the somatosensory thalamus. |
| Q36101696 | Extrasynaptic GABA(A) receptors: their function in the CNS and implications for disease |
| Q37442515 | Extrasynaptic GABAA receptors: form, pharmacology, and function |
| Q42701697 | Functional characterization of GABAA receptor-mediated modulation of cortical neuron network activity in microelectrode array recordings |
| Q38130493 | Functional role of ambient GABA in refining neuronal circuits early in postnatal development |
| Q47675999 | GABA Receptors and the Pharmacology of Sleep. |
| Q57165010 | GABA beyond the synapse: defining the subtype-specific pharmacodynamics of non-synaptic GABA receptors |
| Q42066094 | GABAA , NMDA and mGlu2 receptors tonically regulate inhibition and excitation in the thalamic reticular nucleus. |
| Q48580098 | GABAA and glycine receptor-mediated transmission in rat lamina II neurones: relevance to the analgesic actions of neuroactive steroids |
| Q28586656 | GABAA receptor alpha 4 subunits mediate extrasynaptic inhibition in thalamus and dentate gyrus and the action of gaboxadol |
| Q34537848 | GABAA receptor subtype involvement in addictive behaviour. |
| Q38136071 | GABAA receptor-mediated tonic depolarization in developing neural circuits |
| Q36696598 | GABAB Receptors Regulate Extrasynaptic GABAA Receptors. |
| Q41978499 | GABAergic currents in RT and VB thalamic nuclei follow kinetic pattern of alpha3- and alpha1-subunit-containing GABAA receptors |
| Q36302879 | GABAergic inhibition of histaminergic neurons regulates active waking but not the sleep-wake switch or propofol-induced loss of consciousness |
| Q33954029 | Gamma-aminobutyric acid type A receptor alpha 4 subunit knockout mice are resistant to the amnestic effect of isoflurane |
| Q37344996 | Gamma-aminobutyric acid-mediated neurotransmission in the pontine reticular formation modulates hypnosis, immobility, and breathing during isoflurane anesthesia. |
| Q37784402 | General Anesthetic Actions on GABAA Receptors |
| Q37143127 | General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal |
| Q37823450 | Inhibition of learning and memory by general anesthetics |
| Q37457565 | Inhibition of thalamic excitability by 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine-3-ol: a selective role for delta-GABA(A) receptors |
| Q24608968 | International Union of Pharmacology. LXX. Subtypes of gamma-aminobutyric acid(A) receptors: classification on the basis of subunit composition, pharmacology, and function. Update |
| Q37156667 | Isoflurane modulates excitability in the mouse thalamus via GABA-dependent and GABA-independent mechanisms. |
| Q48433751 | KCC2-deficient mice show reduced sensitivity to diazepam, but normal alcohol-induced motor impairment, gaboxadol-induced sedation, and neurosteroid-induced hypnosis |
| Q51991769 | Lack of generalisation between the GABAA receptor agonist, gaboxadol, and allosteric modulators of the benzodiazepine binding site in the rat drug discrimination procedure. |
| Q36102032 | Mechanisms of neurosteroid interactions with GABA(A) receptors. |
| Q42785877 | Modeling the GABAergic action of etomidate on the thalamocortical system |
| Q48313674 | Modulation of extrasynaptic THIP conductances by GABAA-receptor modulators in mouse neocortex |
| Q35326774 | Molecular basis for the high THIP/gaboxadol sensitivity of extrasynaptic GABA(A) receptors |
| Q37774867 | Molecular mechanisms of general anesthesia |
| Q30459685 | Monaural conductive hearing loss alters the expression of the GluA3 AMPA and glycine receptor α1 subunits in bushy and fusiform cells of the cochlear nucleus |
| Q47134980 | Nestorone® as a Novel Progestin for Nonoral Contraception: Structure-Activity Relationships and Brain Metabolism Studies. |
| Q37043553 | Neuronal Expression and Cell-Type-Specific Gene-Silencing of Best1 in Thalamic Reticular Nucleus Neurons Using pSico-Red System |
| Q30490678 | Neurosteroid regulation of GABA(A) receptors: Focus on the alpha4 and delta subunits |
| Q48304162 | Neurosteroids for a successful pregnancy |
| Q35031754 | Non-neuronal, slow GABA signalling in the ventrobasal thalamus targets δ-subunit-containing GABA(A) receptors |
| Q33958269 | Normal acute behavioral responses to moderate/high dose ethanol in GABAA receptor alpha 4 subunit knockout mice |
| Q36708363 | Patterns of mRNA and protein expression for 12 GABAA receptor subunits in the mouse brain. |
| Q30374468 | Persistent Thalamic Sound Processing Despite Profound Cochlear Denervation |
| Q34053899 | Phosphorylation of GABAA receptors influences receptor trafficking and neurosteroid actions |
| Q89819187 | Photosensitive inhibition of the GABA system in vitro |
| Q37295580 | Presynaptic actions of propofol enhance inhibitory synaptic transmission in isolated solitary tract nucleus neurons. |
| Q48424850 | Probing α4βδ GABAA receptor heterogeneity: differential regional effects of a functionally selective α4β1δ/α4β3δ receptor agonist on tonic and phasic inhibition in rat brain. |
| Q34688851 | Profound desensitization by ambient GABA limits activation of δ-containing GABAA receptors during spillover |
| Q36600032 | Propofol enhances both tonic and phasic inhibitory currents in second-order neurons of the solitary tract nucleus (NTS). |
| Q34193221 | Protein kinase C regulates tonic GABA(A) receptor-mediated inhibition in the hippocampus and thalamus |
| Q33661170 | Prototypic GABA(A) receptor agonist muscimol acts preferentially through forebrain high-affinity binding sites. |
| Q37479936 | Puberty, steroids and GABA(A) receptor plasticity |
| Q35806141 | Quantitative localisation of synaptic and extrasynaptic GABAA receptor subunits on hippocampal pyramidal cells by freeze-fracture replica immunolabelling. |
| Q95269714 | Realising the therapeutic potential of neuroactive steroid modulators of the GABAA receptor |
| Q30452018 | Reduced GABA(A) receptor-mediated tonic inhibition in aged rat auditory thalamus. |
| Q35338580 | Reduction in focal ictal activity following transplantation of MGE interneurons requires expression of the GABAA receptor α4 subunit. |
| Q40153467 | Regional mRNA expression of GABAergic receptor subunits in brains of C57BL/6J and 129P3/J mice: strain and heroin effects |
| Q38861076 | Regulating the Efficacy of Inhibition Through Trafficking of γ-Aminobutyric Acid Type A Receptors. |
| Q34678100 | Retrochalcone derivatives are positive allosteric modulators at synaptic and extrasynaptic GABA(A) receptors in vitro |
| Q35765765 | Reversal of neurosteroid effects at alpha4beta2delta GABAA receptors triggers anxiety at puberty |
| Q34518723 | Ro 15-4513 Antagonizes Alcohol-Induced Sedation in Mice Through αβγ2-type GABA(A) Receptors. |
| Q39938998 | Sensory learning differentially affects GABAergic tonic currents in excitatory neurons and fast spiking interneurons in layer 4 of mouse barrel cortex. |
| Q48461687 | Short-term treatment with gaboxadol improves sleep maintenance and enhances slow wave sleep in adult patients with primary insomnia |
| Q48250819 | Synaptic release generates a tonic GABA(A) receptor-mediated conductance that modulates burst precision in thalamic relay neurons |
| Q40028844 | Taurine is a potent activator of extrasynaptic GABA(A) receptors in the thalamus. |
| Q47816049 | Thalamic δ-subunit containing GABAA receptors promote electrocortical signatures of deep non-REM sleep but do not mediate the effects of etomidate at the thalamus in vivo |
| Q89923969 | The Effects of General Anesthetics on Synaptic Transmission |
| Q36820573 | The cellular, molecular and ionic basis of GABA(A) receptor signalling |
| Q46851027 | The expression of GABAA beta subunit isoforms in synaptic and extrasynaptic receptor populations of mouse dentate gyrus granule cells. |
| Q34432957 | The general anaesthetic etomidate inhibits the excitability of mouse thalamocortical relay neurons by modulating multiple modes of GABAA receptor-mediated inhibition |
| Q37541565 | The impact of tonic GABAA receptor-mediated inhibition on neuronal excitability varies across brain region and cell type. |
| Q30430187 | The influence of stress at puberty on mood and learning: role of the α4βδ GABAA receptor |
| Q39365083 | The orthosteric GABAA receptor ligand Thio-4-PIOL displays distinctly different functional properties at synaptic and extrasynaptic receptors. |
| Q42094690 | The wake-promoting transmitter histamine preferentially enhances α-4 subunit-containing GABAA receptors |
| Q37479497 | Tonic inhibition of accumbal spiny neurons by extrasynaptic α4βδ GABAA receptors modulates the actions of psychostimulants. |
| Q34010417 | Transition to absence seizures and the role of GABA(A) receptors |
| Q37814088 | Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders |
| Q37879217 | Translocator protein (18 kDa) as a target for novel anxiolytics with a favourable side-effect profile |
| Q42035556 | mGluR control of interneuron output regulates feedforward tonic GABAA inhibition in the visual thalamus. |
| Q37138725 | α4βδ GABAA receptors and tonic inhibitory current during adolescence: effects on mood and synaptic plasticity |
| Q28535012 | γ-Hydroxybutyric acid (GHB) is not an agonist of extrasynaptic GABAA receptors |
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