Ethanol modulates synaptic and extrasynaptic GABAA receptors in the thalamus

scientific article published on 13 May 2008

Ethanol modulates synaptic and extrasynaptic GABAA receptors in the thalamus is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1124/JPET.108.139303
P932PMC publication ID2669290
P698PubMed publication ID18477766
P5875ResearchGate publication ID5373317

P50authorGregg E. HomanicsQ42574417
P2093author name stringDev Chandra
Fan Jia
Neil L Harrison
P2860cites workLow-dose alcohol actions on alpha4beta3delta GABAA receptors are reversed by the behavioral alcohol antagonist Ro15-4513Q24548486
Ethanol potently and competitively inhibits binding of the alcohol antagonist Ro15-4513 to alpha4/6beta3delta GABAA receptorsQ24548490
Neuroprotective and abstinence-promoting effects of acamprosate: elucidating the mechanism of actionQ28257222
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GABAA receptor alpha 4 subunits mediate extrasynaptic inhibition in thalamus and dentate gyrus and the action of gaboxadolQ28586656
Effects of Acamprosate on Neuronal Receptors and Ion Channels Expressed inXenopusOocytesQ29030837
Variations on an inhibitory theme: phasic and tonic activation of GABA(A) receptorsQ29616809
Hormonally regulated alpha(4)beta(2)delta GABA(A) receptors are a target for alcoholQ30481041
Alcohol-induced motor impairment caused by increased extrasynaptic GABA(A) receptor activityQ33787183
The contribution of electrophysiology to knowledge of the acute and chronic effects of ethanolQ33832821
Corticothalamic resonance, states of vigilance and mentationQ34080433
Interactions between taurine and ethanol in the central nervous system.Q34159416
Basis of the gabamimetic profile of ethanolQ34216724
A new naturally occurring GABA(A) receptor subunit partnership with high sensitivity to ethanolQ48341591
The role of GABA(A) receptors in the acute and chronic effects of ethanolQ48378043
Effects of ethanol on tonic GABA currents in cerebellar granule cells and mammalian cells recombinantly expressing GABA(A) receptorsQ48470142
The EEG effects of THIP (Gaboxadol) on sleep and waking are mediated by the GABA(A)delta-subunit-containing receptorsQ48472926
Ethanol potentiates GABAergic synaptic transmission in a postsynaptic neuron/synaptic bouton preparation from basolateral amygdalaQ48577598
Polysomnographic and subjective sleep predictors of alcoholic relapseQ48783194
How much alcohol should I use in my experiments?Q49147015
Developmental maturation of synaptic and extrasynaptic GABAA receptors in mouse thalamic ventrobasal neurones.Q51970335
Behavioral evidence for the involvement of gamma-aminobutyric acid in the actions of ethanolQ71763208
Ethanol sensitivity of GABAergic currents in cerebellar granule neurons is not increased by a single amino acid change (R100Q) in the alpha6 GABAA receptor subunitQ80807761
Ethanol enhances alpha 4 beta 3 delta and alpha 6 beta 3 delta gamma-aminobutyric acid type A receptors at low concentrations known to affect humansQ34277701
Perisynaptic localization of delta subunit-containing GABA(A) receptors and their activation by GABA spillover in the mouse dentate gyrus.Q34277867
Thalamic relay functionsQ34434223
Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.Q34440513
Nociceptin/orphanin FQ presynaptically decreases GABAergic transmission and blocks the ethanol-induced increase of GABA release in central amygdalaQ34687187
Ethanol increases GABAergic transmission at both pre- and postsynaptic sites in rat central amygdala neuronsQ34763227
Tonically active GABA A receptors: modulating gain and maintaining the tone.Q35757312
Aspects of the homeostaic plasticity of GABAA receptor-mediated inhibitionQ35940390
The tipsy terminal: presynaptic effects of ethanolQ36166542
Taurine analogues; a new class of therapeutics: retrospect and prospectsQ36230330
Ethanol modulation of GABAergic transmission: the view from the sliceQ36373898
GABAA receptors in the thalamus: alpha4 subunit expression and alcohol sensitivity.Q36830487
Thalamic synchrony and dynamic regulation of global forebrain oscillations.Q36838195
Does ethanol act preferentially via selected brain GABAA receptor subtypes? the current evidence is ambiguous.Q36859917
Taurine is a potent activator of extrasynaptic GABA(A) receptors in the thalamus.Q40028844
Isoflurane is a potent modulator of extrasynaptic GABA(A) receptors in the thalamusQ40032942
The delta subunit of gamma-aminobutyric acid type A receptors does not confer sensitivity to low concentrations of ethanol.Q40354319
Actions of acute and chronic ethanol on presynaptic terminals.Q40355245
Ethanol enhances gamma-aminobutyric acid responses in a subpopulation of nucleus accumbens neurons: role of metabotropic glutamate receptors.Q41731185
Competing presynaptic and postsynaptic effects of ethanol on cerebellar purkinje neuronsQ42023515
Intact synaptic GABAergic inhibition and altered neurosteroid modulation of thalamic relay neurons in mice lacking delta subunit.Q42438034
GABA(A) receptors: immunocytochemical distribution of 13 subunits in the adult rat brain.Q42497057
Brain steroidogenesis mediates ethanol modulation of GABAA receptor activity in rat hippocampus.Q42631943
The sleep of abstinent pure primary alcoholic patients: natural course and relationship to relapseQ43405068
Kinetic and pharmacological properties of GABA(A) receptors in single thalamic neurons and GABA(A) subunit expressionQ43792339
Diurnal effects of acute and chronic administration of ethanol on sleep in ratsQ44116460
Ethanol antagonizes kainate receptor-mediated inhibition of evoked GABA(A) inhibitory postsynaptic currents in the rat hippocampal CA1 regionQ44220841
Alcohol enhances GABAergic transmission to cerebellar granule cells via an increase in Golgi cell excitability.Q44844941
Low ethanol concentrations selectively augment the tonic inhibition mediated by delta subunit-containing GABAA receptors in hippocampal neurons.Q45072876
Increased GABA release in the central amygdala of ethanol-dependent rats.Q45146982
Ethanol potentiation of GABAergic synaptic transmission may be self-limiting: role of presynaptic GABA(B) receptors.Q45163153
Comparison of two forms of long-term potentiation in single hippocampal neuronsQ46461855
Alcohol is a potent stimulant of immature neuronal networks: implications for fetal alcohol spectrum disorderQ46586245
Single-amino-acid difference in the sequence of alpha6 subunit dramatically increases the ethanol sensitivity of recombinant GABAA receptorsQ46621166
An extrasynaptic GABAA receptor mediates tonic inhibition in thalamic VB neuronsQ46703347
The expression of GABAA beta subunit isoforms in synaptic and extrasynaptic receptor populations of mouse dentate gyrus granule cells.Q46851027
Extrasynaptic GABAA receptors of thalamocortical neurons: a molecular target for hypnotics.Q46851461
GABAA receptor-mediated tonic inhibition in thalamic neurons.Q46851471
Functional consequences of GABAA receptor alpha 4 subunit deletion on synaptic and extrasynaptic currents in mouse dentate granule cellsQ46857489
Calcium release from presynaptic internal stores is required for ethanol to increase spontaneous gamma-aminobutyric acid release onto cerebellum Purkinje neuronsQ48095757
Synaptic release generates a tonic GABA(A) receptor-mediated conductance that modulates burst precision in thalamic relay neuronsQ48250819
Recombinant GABAA receptor function and ethanolQ48267001
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)475-482
P577publication date2008-05-13
P1433published inJournal of Pharmacology and Experimental TherapeuticsQ1500272
P1476titleEthanol modulates synaptic and extrasynaptic GABAA receptors in the thalamus
P478volume326

Reverse relations

cites work (P2860)
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