scholarly article | Q13442814 |
P50 | author | Koji Eto | Q87047082 |
Hitoshi Takizawa | Q38523964 | ||
Yohei Morita | Q41779368 | ||
P2093 | author name string | Satoshi Yamazaki | |
Kiyoshi Takatsu | |||
Noriko Tamura | |||
Satoshi Takaki | |||
Hiromitsu Nakauchi | |||
Ichiro Manabe | |||
Naoya Takayama | |||
Satoshi Nishimura | |||
Shinya Goto | |||
Atsushi Oda | |||
Akira Sawaguchi | |||
Hidekazu Nishikii | |||
Sei Kakinuma | |||
Satoshi Okamura | |||
P2860 | cites work | Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton | Q24293554 |
Src kinase activation by direct interaction with the integrin β cytoplasmic domain | Q24298960 | ||
PTP-1B is an essential positive regulator of platelet integrin signaling | Q24317102 | ||
Newly identified genetic risk variants for celiac disease related to the immune response | Q24654340 | ||
Glycoprotein VI-dependent and -independent pathways of thrombus formation in vivo | Q24669536 | ||
Signal-dependent translation of a regulatory protein, Bcl-3, in activated human platelets | Q24675173 | ||
The integrin beta tail is required and sufficient to regulate adhesion signaling to Rac1. | Q44177176 | ||
Specification of the direction of adhesive signaling by the integrin beta cytoplasmic domain | Q46171254 | ||
A new functional role of the fibrinogen RGD motif as the molecular switch that selectively triggers integrin alphaIIbbeta3-dependent RhoA activation during cell spreading | Q46546710 | ||
Identification of a fibrin-independent platelet contractile mechanism regulating primary hemostasis and thrombus growth. | Q46725762 | ||
Tyrosine phosphorylation of the integrin beta 3 subunit regulates beta 3 cleavage by calpain. | Q53602922 | ||
Enhanced engraftment of hematopoietic stem/progenitor cells by the transient inhibition of an adaptor protein, Lnk. | Q53645271 | ||
Regional localization of Fyn in adult brain; studies with mice in which fyn gene was replaced by lacZ | Q72625240 | ||
Beta3 tyrosine phosphorylation in alphaIIbbeta3 (platelet membrane GP IIb-IIIa) outside-in integrin signaling | Q74314932 | ||
Real-time in vivo imaging of platelets, tissue factor and fibrin during arterial thrombus formation in the mouse | Q74817597 | ||
Rac GTPases differentially integrate signals regulating hematopoietic stem cell localization | Q80385968 | ||
Quantification of self-renewal capacity in single hematopoietic stem cells from normal and Lnk-deficient mice | Q81813892 | ||
Enhanced hematopoiesis by hematopoietic progenitor cells lacking intracellular adaptor protein, Lnk | Q24675202 | ||
The adaptor molecule Lnk negatively regulates tumor necrosis factor-alpha-dependent VCAM-1 expression in endothelial cells through inhibition of the ERK1 and -2 pathways | Q28236956 | ||
Integrins: dynamic scaffolds for adhesion and signaling in platelets | Q28267584 | ||
Growth and maturation of megakaryocytes is regulated by Lnk/Sh2b3 adaptor protein through crosstalk between cytokine- and integrin-mediated signals | Q28278879 | ||
Lnk negatively regulates self-renewal of hematopoietic stem cells by modifying thrombopoietin-mediated signal transduction | Q28287126 | ||
Lnk inhibits erythropoiesis and Epo-dependent JAK2 activation and downstream signaling pathways | Q28306960 | ||
Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction | Q28308221 | ||
Thrombin-initiated platelet activation in vivo is vWF independent during thrombus formation in a laser injury model | Q28509120 | ||
Inhibition of plasminogen activator inhibitor-1: its mechanism and effectiveness on coagulation and fibrosis | Q28579222 | ||
The WAVE2/Abi1 complex differentially regulates megakaryocyte development and spreading: implications for platelet biogenesis and spreading machinery | Q28589476 | ||
ADAP is required for normal alphaIIbbeta3 activation by VWF/GP Ib-IX-V and other agonists. | Q30159628 | ||
In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue | Q30481061 | ||
The molecular adapter SLP-76 relays signals from platelet integrin alphaIIbbeta3 to the actin cytoskeleton. | Q31673052 | ||
Eph kinases and ephrins support thrombus growth and stability by regulating integrin outside-in signaling in platelets. | Q33895889 | ||
Integrins and Src: dynamic duo of adhesion signaling | Q34432517 | ||
Cytokines regulate postnatal hematopoietic stem cell expansion: opposing roles of thrombopoietin and LNK. | Q34958781 | ||
Platelets in atherothrombosis | Q34986345 | ||
Adaptors as central mediators of signal transduction in immune cells | Q35055629 | ||
Integrin regulation of cell signalling and motility. | Q35780436 | ||
Laminin stimulates spreading of platelets through integrin alpha6beta1-dependent activation of GPVI. | Q35848605 | ||
The antithrombotic potential of selective blockade of talin-dependent integrin alpha IIb beta 3 (platelet GPIIb-IIIa) activation | Q35868825 | ||
Cytokine signaling and hematopoietic homeostasis are disrupted in Lnk-deficient mice | Q36369746 | ||
Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis | Q36402414 | ||
In vivo thrombus formation | Q36884296 | ||
Platelet integrin adhesive functions and signaling | Q36909800 | ||
Novel therapeutic targets at the platelet vascular interface. | Q37049864 | ||
Control of B cell production by the adaptor protein lnk. Definition Of a conserved family of signal-modulating proteins | Q37624302 | ||
Analysis of Fyn function in hemostasis and alphaIIbbeta3-integrin signaling | Q39989355 | ||
Integrin cytoplasmic tyrosine motif is required for outside-in alphaIIbbeta3 signalling and platelet function | Q41700251 | ||
Involvement of Src kinases and PLCgamma2 in clot retraction | Q42026902 | ||
Kinetic regulation of beta 3 integrin tyrosine phosphorylation | Q44164527 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 179-190 | |
P577 | publication date | 2009-12-21 | |
P1433 | published in | Journal of Clinical Investigation | Q3186904 |
P1476 | title | Lnk regulates integrin alphaIIbbeta3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo | |
P478 | volume | 120 |
Q56000938 | Determination of system level alterations in host transcriptome due to Zika virus (ZIKV) Infection in retinal pigment epithelium |
Q53205345 | Dok-1 negatively regulates platelet integrin αIIbβ3 outside-in signalling and inhibits thrombosis in mice. |
Q42582678 | Essential in vivo roles of the C-type lectin receptor CLEC-2: embryonic/neonatal lethality of CLEC-2-deficient mice by blood/lymphatic misconnections and impaired thrombus formation of CLEC-2-deficient platelets. |
Q35694571 | Evaluation of targeting c-Src by the RGT-containing peptide as a novel antithrombotic strategy |
Q33413336 | Expandable megakaryocyte cell lines enable clinically applicable generation of platelets from human induced pluripotent stem cells |
Q38000164 | Factor XIII is a key molecule at the intersection of coagulation and fibrinolysis as well as inflammation and infection control |
Q36194061 | Functional Effect of the Mutations Similar to the Cleavage during Platelet Activation at Integrin β3 Cytoplasmic Tail when Expressed in Mouse Platelets |
Q42742651 | Gene transfer of the adaptor Lnk (SH2B3) prevents porcine endothelial cell activation and apoptosis: implication for xenograft's cytoprotection |
Q37738343 | Genetics of atherothrombosis and thrombophilia |
Q30537307 | Hierarchical organization in the hemostatic response and its relationship to the platelet-signaling network |
Q27310713 | IL-1α induces thrombopoiesis through megakaryocyte rupture in response to acute platelet needs |
Q89820694 | Imaging Platelet Processes and Function-Current and Emerging Approaches for Imaging in vitro and in vivo |
Q64948132 | Impact of genetic polymorphisms on platelet function and response to anti platelet drugs. |
Q30514057 | In vivo imaging visualizes discoid platelet aggregations without endothelium disruption and implicates contribution of inflammatory cytokine and integrin signaling |
Q33911416 | In vivo real-time two-photon microscopic imaging of platelet aggregation induced by selective laser irradiation to the endothelium created in the beta-actin-green fluorescent protein transgenic mice |
Q38214958 | Insights into platelet-based control of coagulation. |
Q38644725 | Integrin αIIbβ3 outside-in signaling. |
Q47962159 | Integrin αvβ3 enhances the suppressive effect of interferon-γ on hematopoietic stem cells. |
Q35651764 | Integrin-αvβ3 regulates thrombopoietin-mediated maintenance of hematopoietic stem cells |
Q35987858 | LNK (SH2B3) is a key regulator of integrin signaling in endothelial cells and targets α-parvin to control cell adhesion and migration. |
Q40645397 | LNK/SH2B3 Loss of Function Promotes Atherosclerosis and Thrombosis |
Q26770863 | Linkage between the mechanisms of thrombocytopenia and thrombopoiesis |
Q35545925 | Nov/CCN3 regulates long-term repopulating activity of murine hematopoietic stem cells via integrin αvβ3 |
Q44522050 | Platelet Integrins in Tumor Metastasis: Do They Represent a Therapeutic Target? |
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Q26820857 | Platelet-based coagulation: different populations, different functions |
Q37081746 | Platelets as cellular effectors of inflammation in vascular diseases |
Q27026899 | Pluripotent stem cells reveal the developmental biology of human megakaryocytes and provide a source of platelets for clinical application |
Q35033219 | Recent findings in the genetics of blood pressure and hypertension traits |
Q38050407 | Role of the adaptor protein LNK in normal and malignant hematopoiesis |
Q38359111 | Shared genetic aetiology of coronary artery disease and atherosclerotic stroke - 2015. |
Q35791236 | TMEM16F is required for phosphatidylserine exposure and microparticle release in activated mouse platelets |
Q29417153 | The ATXN2-SH2B3 locus is associated with peripheral arterial disease: an electronic medical record-based genome-wide association study |
Q92881863 | The GABA receptor GABRR1 is expressed on and functional in hematopoietic stem cells and megakaryocyte progenitors |
Q38044625 | The Lnk adaptor protein: a key regulator of normal and pathological hematopoiesis |
Q38903897 | The function of SH2B3 (LNK) in the kidney |
Q35540524 | The genetic basis of peripheral arterial disease: current knowledge, challenges, and future directions |
Q26748869 | The impact of genome-wide association studies on the pathophysiology and therapy of cardiovascular disease |
Q39292396 | The role of LNK/SH2B3 genetic alterations in myeloproliferative neoplasms and other hematological disorders |
Q33392928 | Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells |
Q34181566 | Vinculin Is Indispensable for Repopulation by Hematopoietic Stem Cells, Independent of Integrin Function |
Q35574330 | Visualization of in vivo thromboprophylactic and thrombolytic efficacy of enoxaparin in laser-induced vascular endothelial injury model using multiphoton microscopy |
Q89777077 | Whole-exome sequencing in evaluation of patients with venous thromboembolism |
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