Synaptic correlates of fear extinction in the amygdala

scientific article

Synaptic correlates of fear extinction in the amygdala is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/NN.2499
P932PMC publication ID2847017
P698PubMed publication ID20208529
P5875ResearchGate publication ID41809144

P2093author name stringDenis Paré
Taiju Amano
Cagri T Unal
P2860cites workDistribution of GABA immunoreactivity in the amygdaloid complex of the cat.Q36762800
Organization of intra-amygdaloid circuitries in the rat: an emerging framework for understanding functions of the amygdalaQ41639943
Switching on and off fear by distinct neuronal circuits.Q42438392
Amygdaloid projections to the mesencephalon, pons and medulla oblongata in the catQ42442331
Projections of the medial and lateral prefrontal cortices to the amygdala: a Phaseolus vulgaris leucoagglutinin study in the rat.Q42524163
The amygdala is essential for the development of neuronal plasticity in the medial geniculate nucleus during auditory fear conditioning in rats.Q43540500
Facilitation of conditioned fear extinction by systemic administration or intra-amygdala infusions of D-cycloserine as assessed with fear-potentiated startle in rats.Q43918852
Bidirectional synaptic plasticity in intercalated amygdala neurons and the extinction of conditioned fear responsesQ44209093
The distribution of dopamine D1 receptor and mu-opioid receptor 1 receptor immunoreactivities in the amygdala and interstitial nucleus of the posterior limb of the anterior commissure: relationships to tyrosine hydroxylase and opioid peptide terminaQ44331221
Electrophysiological characteristics of amygdaloid central nucleus neurons during Pavlovian fear conditioning in the rabbitQ45087467
Block of gamma-aminobutyric acid-A receptor insertion in the amygdala impairs extinction of conditioned fear.Q45989556
Projections from the lateral part of the central amygdalar nucleus to the postulated fear conditioning circuit.Q46001694
Stimulation of Medial Prefrontal Cortex Decreases the Responsiveness of Central Amygdala Output NeuronsQ48189814
A description of the amygdaloid complex in the rat and cat with observations on intra-amygdaloid axonal connectionsQ48203376
Consolidation of fear extinction requires NMDA receptor-dependent bursting in the ventromedial prefrontal cortexQ48243061
Amygdalar NMDA receptors are critical for new fear learning in previously fear-conditioned rats.Q48380126
Lesions of the basal amygdala block expression of conditioned fear but not extinction.Q48723193
Two different lateral amygdala cell populations contribute to the initiation and storage of memory.Q48829280
Light microscopic localization of brain opiate receptors: a general autoradiographic method which preserves tissue qualityQ48918925
Different lateral amygdala outputs mediate reactions and actions elicited by a fear-arousing stimulus.Q51083974
Evidence that GABA transmission mediates context-specific extinction of learned fear.Q51092856
Conditioned inhibition of fear resulting from negative CS-US contingenciesQ51335178
Information cascade from primary auditory cortex to the amygdala: corticocortical and corticoamygdaloid projections of temporal cortex in the ratQ71614992
The intercalated cell masses project to the central and medial nuclei of the amygdala in catsQ72776610
An inhibitory interface gates impulse traffic between the input and output stations of the amygdalaQ73212264
Neuropeptide S-mediated control of fear expression and extinction: role of intercalated GABAergic neurons in the amygdalaQ24655895
Amygdala, medial prefrontal cortex, and hippocampal function in PTSDQ28256150
Mechanisms of fear extinctionQ28278209
Neural mechanisms of extinction learning and retrievalQ29616240
Neurons in medial prefrontal cortex signal memory for fear extinctionQ29619996
Amygdala intercalated neurons are required for expression of fear extinctionQ30483357
Context-dependent neuronal activity in the lateral amygdala represents fear memories after extinction.Q30496479
Extinction of fear-potentiated startle: blockade by infusion of an NMDA antagonist into the amygdalaQ34242260
The lateral amygdaloid nucleus: sensory interface of the amygdala in fear conditioningQ34321108
Structural and functional plasticity of the human brain in posttraumatic stress disorderQ35580511
New vistas on amygdala networks in conditioned fearQ35814347
Presence and acquired origin of reduced recall for fear extinction in PTSD: results of a twin studyQ36648583
Training-induced changes in the expression of GABAA-associated genes in the amygdala after the acquisition and extinction of Pavlovian fearQ36744289
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)489-494
P577publication date2010-03-07
P1433published inNature NeuroscienceQ1535359
P1476titleSynaptic correlates of fear extinction in the amygdala
P478volume13

Reverse relations

cites work (P2860)
Q64285443A model of amygdala function following plastic changes at specific synapses during extinction
Q30443504A model of amygdala-hippocampal-prefrontal interaction in fear conditioning and extinction in animals
Q43191780A pavlovian model of the amygdala and its influence within the medial temporal lobe
Q97592388A reciprocal inhibition model of alternations between under-/overemotional modulatory states in patients with PTSD
Q57177225A translational perspective on neural circuits of fear extinction: Current promises and challenges
Q34310202Activation of the infralimbic cortex in a fear context enhances extinction learning
Q57292216Acute and long-lasting effects of oxytocin in cortico-limbic circuits: consequences for fear recall and extinction
Q100513530Adult neurogenesis alters response to an aversive distractor in a labyrinth maze without affecting spatial learning or memory
Q36184942Alteration of the Centromedial Amygdala Glutamatergic Synapses by the BDNF Val66Met Polymorphism
Q40460932Altered activity of the medial prefrontal cortex and amygdala during acquisition and extinction of an active avoidance task.
Q33866449Amount of fear extinction changes its underlying mechanisms.
Q47109472Amygdala Plasticity and Pain
Q92736517Amygdala Reward Neurons Form and Store Fear Extinction Memory
Q29248204Amygdala hyperactivity and tonotopic shift after salicylate exposure
Q26852300Amygdala microcircuits controlling learned fear
Q27028062Amygdala microcircuits mediating fear expression and extinction
Q35661585Amygdala regulation of fear and emotionality in fragile X syndrome
Q28652688Amygdala-prefrontal interactions in (mal)adaptive learning
Q35592859Anticorrelated resting-state functional connectivity in awake rat brain.
Q48463879Aversive-bias and stage-selectivity in neurons of the primate amygdala during acquisition, extinction, and overnight retention
Q27304422Bi-Directional Tuning of Amygdala Sensitivity in Combat Veterans Investigated with fMRI.
Q36302912Brain activation during fear conditioning in humans depends on genetic variations related to functioning of the hypothalamic-pituitary-adrenal axis: first evidence from two independent subsamples.
Q46767561Brain morphology correlates of interindividual differences in conditioned fear acquisition and extinction learning
Q34889241CB1 augments mGluR5 function in medial prefrontal cortical neurons to inhibit amygdala hyperactivity in an arthritis pain model
Q38736569Calcium signalling in medial intercalated cell dendrites and spines.
Q36471452Candesartan ameliorates impaired fear extinction induced by innate immune activation
Q34355727Cannabinoid modulation of fear extinction brain circuits: a novel target to advance anxiety treatment
Q47293470Cellular and oscillatory substrates of fear extinction learning.
Q35636279Cellular correlates of enhanced anxiety caused by acute treatment with the selective serotonin reuptake inhibitor fluoxetine in rats
Q93195982Chemogenetic activation of an infralimbic cortex to basolateral amygdala projection promotes resistance to acute social defeat stress
Q93216241Chronic inhibition of GABA synthesis in the infralimbic cortex facilitates conditioned safety memory and reduces contextual fear
Q41892156Combined Optogenetic and Freeze-fracture Replica Immunolabeling to Examine Input-specific Arrangement of Glutamate Receptors in the Mouse Amygdala
Q41353871Computational search for hypotheses concerning the endocannabinoid contribution to the extinction of fear conditioning
Q39812467Contextual fear conditioning depresses infralimbic excitability
Q90067546Cortical oxygenation during exposure therapy - in situ fNIRS measurements in arachnophobia
Q96229748D-Serine as the gatekeeper of NMDA receptor activity: implications for the pharmacologic management of anxiety disorders
Q47844335DBS in Treatment of Post-Traumatic Stress Disorder
Q38757215Deep Brain Stimulation in Animal Models of Fear, Anxiety, and Posttraumatic Stress Disorder
Q30587237Deep brain stimulation of the basolateral amygdala for treatment-refractory combat post-traumatic stress disorder (PTSD): study protocol for a pilot randomized controlled trial with blinded, staggered onset of stimulation
Q37080190Deep brain stimulation of the ventral striatum increases BDNF in the fear extinction circuit.
Q37676473Delta-subunit-containing GABAA-receptors mediate tonic inhibition in paracapsular cells of the mouse amygdala
Q43598973Depletion of perineuronal nets in the amygdala to enhance the erasure of drug memories
Q30474522Design of a neurally plausible model of fear learning.
Q50635830Different fear states engage distinct networks within the intercalated cell clusters of the amygdala.
Q27303749Directional theta coherence in prefrontal cortical to amygdalo-hippocampal pathways signals fear extinction
Q48112087Discriminative auditory fear learning requires both tuned and nontuned auditory pathways to the amygdala.
Q47639733Dopamine Regulation of Amygdala Inhibitory Circuits for Expression of Learned Fear
Q50632990Dousing the flames of fear.
Q50205866Dynamic expression of FKBP5 in the medial prefrontal cortex regulates resiliency to conditioned fear
Q36901973Effect of D-cycloserine in conjunction with fear extinction training on extracellular signal-regulated kinase activation in the medial prefrontal cortex and amygdala in rat.
Q57040144Effects of acute Δ9-tetrahydrocannabinol on next-day extinction recall is mediated by post-extinction resting-state brain dynamics
Q47930741Efferents of anterior cingulate areas 24a and 24b and midcingulate areas 24a' and 24b' in the mouse.
Q92641689Elevated dopamine signaling from ventral tegmental area to prefrontal cortical parvalbumin neurons drives conditioned inhibition
Q24629806Emotional processing in anterior cingulate and medial prefrontal cortex
Q37925172Endocannabinoid signaling in the amygdala: anatomy, synaptic signaling, behavior, and adaptations to stress
Q93020824Environmental variables that ameliorate extinction learning deficits in the 129S1/SvlmJ mouse strain
Q36050594Erasing fear memories with extinction training.
Q50083269Exposure to an Obesogenic Diet During Adolescence Leads to Abnormal Maturation of Neural and Behavioral Substrates Underpinning Fear and Anxiety
Q61805017Expression and Function of Neuron-Glia-Related Cell Adhesion Molecule (NrCAM) in the Amygdalar Pathway
Q37156104Failure of neural responses to safety cues in schizophrenia
Q38777375Fear Memory
Q34076976Fear and safety engage competing patterns of theta-gamma coupling in the basolateral amygdala
Q30459672Fear conditioning, synaptic plasticity and the amygdala: implications for posttraumatic stress disorder
Q48008381Fear extinction and acute stress reactivity reveal a role of LPA(1) receptor in regulating emotional-like behaviors.
Q28254365Fear extinction as a model for translational neuroscience: ten years of progress
Q37341518Fear extinction causes target-specific remodeling of perisomatic inhibitory synapses
Q36948897Fear extinction induces mGluR5-mediated synaptic and intrinsic plasticity in infralimbic neurons
Q30418429Fear renewal preferentially activates ventral hippocampal neurons projecting to both amygdala and prefrontal cortex in rats.
Q41270330Forgetting fear associations through tES: which memory process might be critical?
Q90745368From Isolated Emotional Memories to Their Competition During Conflict
Q26851172From Pavlov to PTSD: the extinction of conditioned fear in rodents, humans, and anxiety disorders
Q36045805From circuits to behaviour in the amygdala
Q43481265Functional connectivity of the main intercalated nucleus of the mouse amygdala
Q42182070Functional expression of the GABA(A) receptor α2 and α3 subunits at synapses between intercalated medial paracapsular neurons of mouse amygdala
Q30446954Gating of fear in prelimbic cortex by hippocampal and amygdala inputs.
Q34395647Grin1 receptor deletion within CRF neurons enhances fear memory
Q35545600Highly differentiated cellular and circuit properties of infralimbic pyramidal neurons projecting to the periaqueductal gray and amygdala
Q24626934Hippocampal and prefrontal projections to the basal amygdala mediate contextual regulation of fear after extinction.
Q33923610Hippocampal--prefrontal BDNF and memory for fear extinction
Q27310813Hunger Promotes Fear Extinction by Activation of an Amygdala Microcircuit.
Q42712789Impact of infralimbic inputs on intercalated amygdala neurons: a biophysical modeling study
Q26767340Impaired Functional Connectivity in the Prefrontal Cortex: A Mechanism for Chronic Stress-Induced Neuropsychiatric Disorders
Q36591220In vivo knockdown of GAD67 in the amygdala disrupts fear extinction and the anxiolytic-like effect of diazepam in mice
Q36521000Inhibition of fear by learned safety signals: a mini-symposium review
Q26828055Inhibitory networks of the amygdala for emotional memory
Q47696154Interplay of prefrontal cortex and amygdala during extinction of drug seeking.
Q35036750Is an epigenetic switch the key to persistent extinction?
Q91637255Kainate receptor auxiliary subunit NETO2 is required for normal fear expression and extinction
Q98499788L-DOPA and consolidation of fear extinction learning among women with posttraumatic stress disorder
Q35844258Lack of cortico-limbic coupling in bipolar disorder and schizophrenia during emotion regulation
Q41476781Large intercalated neurons of amygdala relay noxious sensory information.
Q39247666Learning enhances intrinsic excitability in a subset of lateral amygdala neurons
Q46657621Long-term neural correlates of reversible fear learning in the lateral amygdala.
Q47914166Long-term potentiation at excitatory synaptic inputs to the intercalated cell masses of the amygdala
Q48463891Low-frequency stimulation depresses the primate anterior-cingulate-cortex and prevents spontaneous recovery of aversive memories.
Q38428844Maintenance of aversive memories shown by fear extinction-impaired phenotypes is associated with increased activity in the amygdaloid-prefrontal circuit
Q58557874Mechanisms of fear learning and extinction: synaptic plasticity-fear memory connection
Q28396555Mechanisms to medicines: elucidating neural and molecular substrates of fear extinction to identify novel treatments for anxiety disorders
Q38054599Medial prefrontal cortex: multiple roles in fear and extinction
Q30402294Medial prefrontal cortical innervation of the intercalated nuclear region of the amygdala
Q37863149Modulation of fear memory by retrieval and extinction: a clue for memory deconsolidation
Q36532070Morphology, PKCδ expression, and synaptic responsiveness of different types of rat central lateral amygdala neurons
Q30357301Mouse models of fear-related disorders: Cell-type-specific manipulations in amygdala.
Q38280778Multiple mechanistically distinct modes of endocannabinoid mobilization at central amygdala glutamatergic synapses
Q93010692NPY2 Receptors Reduce Tonic Action Potential-Independent GABAB Currents in the Basolateral Amygdala
Q33713267Nasal application of neuropeptide S inhibits arthritis pain-related behaviors through an action in the amygdala
Q26853333Neural and cellular mechanisms of fear and extinction memory formation
Q91559995Neural circuits underlying a psychotherapeutic regimen for fear disorders
Q26859202Neural mechanisms of pain and alcohol dependence
Q33906630Neural structures mediating expression and extinction of platform-mediated avoidance.
Q24630212Neural substrates for the distinct effects of presynaptic group III metabotropic glutamate receptors on extinction of contextual fear conditioning in mice
Q30461311Neural substrates of childhood anxiety disorders: a review of neuroimaging findings
Q50429791Neurobiology of fear and specific phobias.
Q64244268Neuromodulation Strategies in Post-Traumatic Stress Disorder: From Preclinical Models to Clinical Applications
Q34477053Neuronal circuits for fear and anxiety.
Q37235432Neuropeptide S: a novel regulator of pain-related amygdala plasticity and behaviors
Q91601937Neuropeptides at the crossroad of fear and hunger: a special focus on neuropeptide Y
Q38808613New Learning and Unlearning: Strangers or Accomplices in Threat Memory Attenuation?
Q30300197Observation of Distressed Conspecific as a Model of Emotional Trauma Generates Silent Synapses in the Prefrontal-Amygdala Pathway and Enhances Fear Learning, but Ketamine Abolishes those Effects
Q98906979Oestradiol as a neuromodulator of learning and memory
Q40058614On and Off switches in the brain
Q44332493Opioid Inhibition of Intercalated Input to the Central Amygdala.
Q36880278Orexin, stress, and anxiety/panic states
Q35374571Out with the old and in with the new: Synaptic mechanisms of extinction in the amygdala
Q30558405Overlapping neural systems mediating extinction, reversal and regulation of fear
Q42493116Oxytocin suppresses basal glutamatergic transmission but facilitates activity-dependent synaptic potentiation in the medial prefrontal cortex
Q34468302Pain-related increase of excitatory transmission and decrease of inhibitory transmission in the central nucleus of the amygdala are mediated by mGluR1
Q30440363Pain-relief learning in flies, rats, and man: basic research and applied perspectives
Q38268772Pathological circuit function underlying addiction and anxiety disorders.
Q88306394Pathway-Specific Alterations of Cortico-Amygdala Transmission in an Arthritis Pain Model
Q24633256Pharmacological treatment of PTSD - established and new approaches
Q35056006Physiological identification and infralimbic responsiveness of rat intercalated amygdala neurons
Q36374909Pituitary adenylate cyclase-activating polypeptide induces postsynaptically expressed potentiation in the intra-amygdala circuit
Q64230475Plasticity at Thalamo-amygdala Synapses Regulates Cocaine-Cue Memory Formation and Extinction
Q39491252Posterior insular cortex is necessary for conditioned inhibition of fear
Q39043179Posttraumatic Stress Disorder: Perspectives for the Use of Deep Brain Stimulation
Q35989378Prefrontal dopamine regulates fear reinstatement through the downregulation of extinction circuits
Q30578917Prefrontal entrainment of amygdala activity signals safety in learned fear and innate anxiety
Q36201622Prefrontal inputs to the amygdala instruct fear extinction memory formation.
Q92026070Prefrontal somatostatin interneurons encode fear memory
Q38636774Prefrontal-amygdala fear networks come into focus.
Q34608692Prelimbic and infralimbic neurons signal distinct aspects of appetitive instrumental behavior
Q89454956Promoting long-term inhibition of human fear responses by non-invasive transcutaneous vagus nerve stimulation during extinction training
Q47820916Protein kinase C is essential for kainate-induced anxiety-related behavior and glutamatergic synapse upregulation in prelimbic cortex.
Q30419931Psychological and neural mechanisms of experimental extinction: a selective review
Q42970214Reactivation of fear memory renders consolidated amygdala synapses labile
Q35146447Rescue of impaired fear extinction and normalization of cortico-amygdala circuit dysfunction in a genetic mouse model by dietary zinc restriction
Q28257827Revisiting the role of infralimbic cortex in fear extinction with optogenetics
Q91726358Role of Human Ventromedial Prefrontal Cortex in Learning and Recall of Enhanced Extinction
Q42434909Safety encoding in the basal amygdala
Q30438581Safety signals in the primate amygdala
Q35174566Safety signals mitigate the consequences of uncontrollable stress via a circuit involving the sensory insular cortex and bed nucleus of the stria terminalis
Q30466738Seeking a spotless mind: extinction, deconsolidation, and erasure of fear memory
Q30359974Selective Control of Fear Expression by Optogenetic Manipulation of Infralimbic Cortex after Extinction.
Q36061685Sex differences, gonadal hormones and the fear extinction network: implications for anxiety disorders
Q30498563Short-term adaptation of conditioned fear responses through endocannabinoid signaling in the central amygdala
Q49615764Sleep deprivation affects fear memory consolidation: Bi-stable amygdala connectivity with insula and ventromedial prefrontal cortex
Q90741119Social Dominance Modulates Stress-induced Neural Activity in Medial Prefrontal Cortex Projections to the Basolateral Amygdala
Q49599254Spatial Representation of Hippocampal Place Cells in a T-Maze with an Aversive Stimulation.
Q36719882Specific Targeting of the Basolateral Amygdala to Projectionally Defined Pyramidal Neurons in Prelimbic and Infralimbic Cortex.
Q35218437Spontaneous recovery of fear reverses extinction-induced excitability of infralimbic neurons
Q26769043Stress as a one-armed bandit: Differential effects of stress paradigms on the morphology, neurochemistry and behavior in the rodent amygdala
Q35634398Stress, trauma and PTSD: translational insights into the core synaptic circuitry and its modulation.
Q36416743Structure and function of the amygdaloid NPY system: NPY Y2 receptors regulate excitatory and inhibitory synaptic transmission in the centromedial amygdala.
Q47294734Synapse-specific astrocyte gating of amygdala-related behavior
Q30560626Synaptic encoding of fear extinction in mPFC-amygdala circuits
Q39219489Synaptic potentiation in the nociceptive amygdala following fear learning in mice
Q41883330The BDNF Val66Met polymorphism impairs synaptic transmission and plasticity in the infralimbic medial prefrontal cortex
Q26795477The Physiology of Fear: Reconceptualizing the Role of the Central Amygdala in Fear Learning
Q38082742The amygdala and medial prefrontal cortex: partners in the fear circuit
Q30413016The basolateral amygdala determines the effects of fear memory on sleep in an animal model of PTSD
Q30383734The central amygdala as an integrative hub for anxiety and alcohol use disorders
Q39298397The fear circuit revisited: contributions of the basal amygdala nuclei to conditioned fear
Q42274709The intercalated nuclear complex of the primate amygdala
Q48603219The neural consequences of combat stress: long-term follow-up.
Q26786672The role of Neuropeptide Y in fear conditioning and extinction
Q35738226Toward a translational approach to targeting the endocannabinoid system in posttraumatic stress disorder: a critical review of preclinical research.
Q42503930Trace fear conditioning enhances synaptic and intrinsic plasticity in rat hippocampus
Q36129780Uncertainty-Dependent Extinction of Fear Memory in an Amygdala-mPFC Neural Circuit Model.
Q34582789Unique inhibitory synapse with particularly rich endocannabinoid signaling machinery on pyramidal neurons in basal amygdaloid nucleus
Q48413119Viewpoints: Dialogues on the functional role of the ventromedial prefrontal cortex
Q35566621Where and what is the paralaminar nucleus? A review on a unique and frequently overlooked area of the primate amygdala.
Q48057569Wiring Specificity and Synaptic Diversity in the Mouse Lateral Central Amygdala.
Q36329100mGluR₁,5 activation improves network asynchrony and GABAergic synapse attenuation in the amygdala: implication for anxiety-like behavior in DBA/2 mice
Q41718261α2-adrenoceptor-mediated inhibition in the central amygdala blocks fear-conditioning.
Q35598702μ-Opioid Receptor-Mediated Inhibition of Intercalated Neurons and Effect on Synaptic Transmission to the Central Amygdala.

Search more.