Switching on and off fear by distinct neuronal circuits.

scientific article published on 9 July 2008

Switching on and off fear by distinct neuronal circuits. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1025323867
P356DOI10.1038/NATURE07166
P698PubMed publication ID18615015

P50authorCyril HerryQ57005783
P2093author name stringChristian Müller
Andreas Lüthi
Stephane Ciocchi
Lynda Demmou
Verena Senn
P2860cites workEmotion circuits in the brainQ27860733
The role of ventromedial prefrontal cortex in the recovery of extinguished fearQ28143094
Mechanisms of fear extinctionQ28278209
Neurons in medial prefrontal cortex signal memory for fear extinctionQ29619996
Chronic, multisite, multielectrode recordings in macaque monkeysQ30480032
Contextual and auditory fear conditioning are mediated by the lateral, basal, and central amygdaloid nuclei in ratsQ30500317
Damage to the lateral and central, but not other, amygdaloid nuclei prevents the acquisition of auditory fear conditioningQ30500322
Differential fear conditioning induces reciprocal changes in the sensory responses of lateral amygdala neurons to the CS(+) and CS(-).Q30500336
The learning curve: implications of a quantitative analysisQ30832358
Hippocampal inactivation disrupts contextual retrieval of fear memory after extinction.Q32062025
Reciprocal connections between the amygdala and the hippocampal formation, perirhinal cortex, and postrhinal cortex in rat. A reviewQ33981295
Context, ambiguity, and unlearning: sources of relapse after behavioral extinctionQ34159550
Extinction of fear-potentiated startle: blockade by infusion of an NMDA antagonist into the amygdalaQ34242260
The amygdala modulates the consolidation of memories of emotionally arousing experiencesQ34329049
New vistas on amygdala networks in conditioned fearQ35814347
Emotional perseveration: an update on prefrontal-amygdala interactions in fear extinction.Q35909923
Neuronal signalling of fear memoryQ35924365
Contextual and temporal modulation of extinction: behavioral and biological mechanisms.Q36450189
Prefrontal mechanisms in extinction of conditioned fear.Q36483236
Cocaine-induced decision-making deficits are mediated by miscoding in basolateral amygdalaQ36925748
Processing of temporal unpredictability in human and animal amygdala.Q40208173
Context-specificity of relapse: effects of therapist and environmental context on return of fearQ40800411
Fear conditioning enhances short-latency auditory responses of lateral amygdala neurons: Parallel recordings in the freely behaving ratQ41670504
Infralimbic cortex activation increases c-Fos expression in intercalated neurons of the amygdalaQ42488425
Projections of the medial and lateral prefrontal cortices to the amygdala: a Phaseolus vulgaris leucoagglutinin study in the rat.Q42524163
Mitogen-activated protein kinase cascade in the basolateral nucleus of amygdala is involved in extinction of fear-potentiated startle.Q43687987
Organization of amygdaloid projections to the prefrontal cortex and associated striatum in the ratQ43887072
Dopamine-mediated modulation of odour-evoked amygdala potentials during pavlovian conditioningQ43996878
Hippocampal inactivation disrupts the acquisition and contextual encoding of fear extinction.Q46726663
Ventral hippocampal muscimol disrupts context-specific fear memory retrieval after extinction in ratsQ46854109
A receptor that mediates the post-mating switch in Drosophila reproductive behaviour.Q47070137
Auditory-evoked spike firing in the lateral amygdala and Pavlovian fear conditioning: mnemonic code or fear bias?Q47338307
The prefrontal cortex regulates lateral amygdala neuronal plasticity and responses to previously conditioned stimuli.Q48125179
Basolateral amygdala lesions abolish orbitofrontal-dependent reversal impairmentsQ48217752
Acquisition of fear extinction requires activation of NR2B-containing NMDA receptors in the lateral amygdala.Q48314739
Rat amygdaloid neuron responses during auditory discriminationQ48336256
Identification of basolateral amygdala projection cells and interneurons using extracellular recordingsQ48367457
Emotional enhancement of memory via amygdala-driven facilitation of rhinal interactionsQ48424225
Extinction of auditory fear conditioning requires MAPK/ERK activation in the basolateral amygdalaQ48457487
Basolateral amygdaloid multi-unit neuronal correlates of discriminative avoidance learning in rabbitsQ48720297
Lesions of the basal amygdala block expression of conditioned fear but not extinction.Q48723193
Two different lateral amygdala cell populations contribute to the initiation and storage of memory.Q48829280
Compact movable microwire array for long-term chronic unit recording in cerebral cortex of primatesQ50912365
Context modulation of memory for fear extinction in humansQ50962603
Resistance to extinction is associated with impaired immediate early gene induction in medial prefrontal cortex and amygdalaQ50996520
Prefrontal cortex long-term potentiation, but not long-term depression, is associated with the maintenance of extinction of learned fear in mice.Q51057814
Different lateral amygdala outputs mediate reactions and actions elicited by a fear-arousing stimulus.Q51083974
Escape swim network interneurons have diverse roles in behavioral switching and putative arousal in PleurobranchaeaQ73537056
Role of the basolateral amygdala in memory consolidationQ79085655
P433issue7204
P407language of work or nameEnglishQ1860
P304page(s)600-606
P577publication date2008-07-09
P1433published inNatureQ180445
P1476titleSwitching on and off fear by distinct neuronal circuits
P478volume454

Reverse relations

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Q30382249Neurochemical correlates of accumbal dopamine D2 and amygdaloid 5-HT 1B receptor densities on observational learning of aggression.
Q90101961Neuroepigenetic mechanisms underlying fear extinction: emerging concepts
Q48395902Neurogliaform cells of amygdala: a source of slow phasic inhibition in the basolateral complex.
Q64895477Neuromodulation for Treatment-Refractory PTSD.
Q34477053Neuronal circuits for fear and anxiety.
Q98464641Neuronal diversity of the amygdala and the bed nucleus of the stria terminalis
Q47783573Neuronal encoding of the switch from specific to generalized fear
Q28595097Neuropeptide S-Mediated Facilitation of Synaptic Transmission Enforces Subthreshold Theta Oscillations within the Lateral Amygdala
Q36103969Neurophysiological correlates of object recognition in the dorsal subiculum.
Q38808613New Learning and Unlearning: Strangers or Accomplices in Threat Memory Attenuation?
Q50420320Nicotine exposure leads to deficits in differential cued fear conditioning in mice and humans: a potential role of the anterior cingulate cortex
Q40058614On and Off switches in the brain
Q44332493Opioid Inhibition of Intercalated Input to the Central Amygdala.
Q33740875Opposing effects of D-cycloserine on fear despite a common extinction duration: interactions between brain regions and behavior
Q48654851Opposite effects of fear conditioning and extinction on dendritic spine remodelling
Q30434815Optogenetic dissection of neural circuits underlying emotional valence and motivated behaviors
Q60949848Orexin Depolarizes Central Amygdala Neurons via Orexin Receptor 1, Phospholipase C and Sodium-Calcium Exchanger and Modulates Conditioned Fear
Q50527311Over-generalization in youth with anxiety disorders
Q40103310Overexpression of Protein Kinase Mζ in the Hippocampus Enhances Long-Term Potentiation and Long-Term Contextual But Not Cued Fear Memory in Rats.
Q47349650Overlapping memory trace indispensable for linking, but not recalling, individual memories.
Q30558405Overlapping neural systems mediating extinction, reversal and regulation of fear
Q35534876Oxytocin signaling in basolateral and central amygdala nuclei differentially regulates the acquisition, expression, and extinction of context-conditioned fear in rats
Q36948942PTSD and DNA Methylation in Select Immune Function Gene Promoter Regions: A Repeated Measures Case-Control Study of U.S. Military Service Members
Q35543943Pain-related deactivation of medial prefrontal cortical neurons involves mGluR1 and GABAA receptors
Q30844529Parvalbumin-expressing interneurons coordinate hippocampal network dynamics required for memory consolidation
Q38268772Pathological circuit function underlying addiction and anxiety disorders.
Q27333897Patterns of coupled theta activity in amygdala-hippocampal-prefrontal cortical circuits during fear extinction
Q30500044Pax6 is required at the telencephalic pallial-subpallial boundary for the generation of neuronal diversity in the postnatal limbic system
Q39279816Perineuronal nets protect fear memories from erasure
Q37568195Perisomatic GABAergic synapses of basket cells effectively control principal neuron activity in amygdala networks
Q35851816Persistent active avoidance correlates with activity in prelimbic cortex and ventral striatum
Q64285398Persistent pain intensifies recall of consolidated fear memories
Q50026702Perturbation of GABAergic Synapses at the Axon Initial Segment of Basolateral Amygdala Induces Trans-regional Metaplasticity at the Medial Prefrontal Cortex
Q47431728Perturbed connectivity of the amygdala and its subregions with the central executive and default mode networks in chronic pain.
Q34721646Pharmacological enhancement of drug cue extinction learning: translational challenges
Q27006437Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders
Q36374909Pituitary Adenylate Cyclase-Activating Polypeptide Induces Postsynaptically Expressed Potentiation in the Intra-amygdala Circuit
Q30476116Plastic synaptic networks of the amygdala for the acquisition, expression, and extinction of conditioned fear
Q36400690Plasticity of Fear and Safety Neurons of the Amygdala in Response to Fear Extinction
Q47439066Post-training reversible disconnection of the ventral hippocampal-basolateral amygdaloid circuits impairs consolidation of inhibitory avoidance memory in rats
Q33706856Post-training reversible inactivation of the hippocampus enhances novel object recognition memory
Q89554287Posterior parietal cortex mediates fear renewal in a novel context
Q48020770Potential of microRNAs as novel targets in the alleviation of pathological fear
Q41335298Pre-synaptic TrkB in basolateral amygdala neurons mediates BDNF signaling transmission in memory extinction
Q47140920Prefrontal Cortex Drives Distinct Projection Neurons in the Basolateral Amygdala
Q47779016Prefrontal Cortex Stimulation Enhances Fear Extinction Memory in Humans
Q37715147Prefrontal control of fear: more than just extinction.
Q89838175Prefrontal cortex circuits in depression and anxiety: contribution of discrete neuronal populations and target regions
Q30578917Prefrontal entrainment of amygdala activity signals safety in learned fear and innate anxiety
Q36201622Prefrontal inputs to the amygdala instruct fear extinction memory formation.
Q38257319Prefrontal neuronal circuits of contextual fear conditioning.
Q47954570Prefrontal parvalbumin interneurons shape neuronal activity to drive fear expression.
Q92026070Prefrontal somatostatin interneurons encode fear memory
Q47124514Prefrontal-Amygdala Connectivity and State Anxiety during Fear Extinction Recall in Adolescents
Q26773131Prefrontal-Hippocampal Interactions in Memory and Emotion
Q38636774Prefrontal-amygdala fear networks come into focus.
Q48422221Prelimbic prefrontal neurons drive fear expression: a clue for extinction--reconsolidation interactions.
Q48090014Priming stimulation of basal but not lateral amygdala affects long-term potentiation in the rat dentate gyrus in vivo
Q30419931Psychological and neural mechanisms of experimental extinction: a selective review
Q41849490Putting the brakes on fear
Q49789519Quantified Coexpression Analysis of Central Amygdala Subpopulations
Q33823251Re-valuing the amygdala
Q64105220Reactivation of Recall-Induced Neurons in the Infralimbic Cortex and the Basolateral Amygdala After Remote Fear Memory Attenuation
Q47297665Reactivations of emotional memory in the hippocampus-amygdala system during sleep.
Q34415711Reactive searching and infotaxis in odor source localization
Q30480270Reciprocal patterns of c-Fos expression in the medial prefrontal cortex and amygdala after extinction and renewal of conditioned fear
Q37578425Reconsolidation and extinction are dissociable and mutually exclusive processes: behavioral and molecular evidence
Q34292746Recording single neurons' action potentials from freely moving pigeons across three stages of learning
Q64119010Reimplantable Microdrive for Long-Term Chronic Extracellular Recordings in Freely Moving Rats
Q41654430Renewal of extinguished fear activates ventral hippocampal neurons projecting to the prelimbic and infralimbic cortices in rats
Q35146447Rescue of impaired fear extinction and normalization of cortico-amygdala circuit dysfunction in a genetic mouse model by dietary zinc restriction
Q38592633Resolving the neural circuits of anxiety
Q50642494Retrieval of conditioned fear activates the basolateral and intercalated nucleus of amygdala
Q30364631Retrieving fear memories, as time goes by…
Q41906656Reversible Inactivation of the Bed Nucleus of the Stria Terminalis Prevents Reinstatement But Not Renewal of Extinguished Fear(1,2,3)
Q41108007Reversible Inactivation of the Higher Order Auditory Cortex during Fear Memory Consolidation Prevents Memory-Related Activity in the Basolateral Amygdala during Remote Memory Retrieval
Q36007841Revisiting the hippocampal-amygdala pathway in primates: association with immature-appearing neurons
Q37350962Risk for anxiety and implications for treatment: developmental, environmental, and genetic factors governing fear regulation
Q37876896Role of the basolateral amygdala and NMDA receptors in higher-order conditioned fear
Q48151810Role of the bed nucleus of the stria terminalis in aversive learning and memory.
Q30410912SERT and uncertainty: serotonin transporter expression influences information processing biases for ambiguous aversive cues in mice.
Q42434909Safety encoding in the basal amygdala
Q30438581Safety signals in the primate amygdala
Q30466738Seeking a spotless mind: extinction, deconsolidation, and erasure of fear memory
Q33941014Segregated populations of hippocampal principal CA1 neurons mediating conditioning and extinction of contextual fear
Q26852984Sensitive periods in affective development: nonlinear maturation of fear learning
Q37502461Sensory cortical population dynamics uniquely track behavior across learning and extinction
Q37051560Serotonin 5-HT7 Receptor in the Ventral Hippocampus Modulates the Retrieval of Fear Memory and Stress-Induced Defecation.
Q37266163Sex differences and chronic stress effects on the neural circuitry underlying fear conditioning and extinction.
Q36061685Sex differences, gonadal hormones and the fear extinction network: implications for anxiety disorders
Q38784548Sex specific recruitment of a medial prefrontal cortex-hippocampal-thalamic system during context-dependent renewal of responding to food cues in rats
Q37432170Sex-specific mechanisms for responding to stress
Q35666027Sex-specific neuroanatomical correlates of fear expression in prefrontal-amygdala circuits
Q30499971Sidman instrumental avoidance initially depends on lateral and basal amygdala and is constrained by central amygdala-mediated Pavlovian processes.
Q33654116Single-unit activity in the medial prefrontal cortex during immediate and delayed extinction of fear in rats
Q90704175State-specific gating of salient cues by midbrain dopaminergic input to basal amygdala
Q37130259Steps in the design, development and formative evaluation of obesity prevention-related behavior change trials
Q34283226Stimulation of serotonin 2A receptors facilitates consolidation and extinction of fear memory in C57BL/6J mice.
Q30556974Stimulus-specific enhancement of fear extinction during slow-wave sleep
Q57169437Stress in Regulation of GABA Amygdala System and Relevance to Neuropsychiatric Diseases
Q34139931Stress-induced prefrontal reorganization and executive dysfunction in rodents
Q92212844Structural and functional neuroimaging studies in generalized anxiety disorder: a systematic review
Q30484368Sustained conditioned responses in prelimbic prefrontal neurons are correlated with fear expression and extinction failure
Q30467444Synaptic Interactions Underlying Synchronized Inhibition in the Basal Amygdala: Evidence for Existence of Two Types of Projection Cells
Q36656544Synaptic Organization of Perisomatic GABAergic Inputs onto the Principal Cells of the Mouse Basolateral Amygdala
Q36144757Synaptic competition in the lateral amygdala and the stimulus specificity of conditioned fear: a biophysical modeling study
Q30493920Synaptic correlates of fear extinction in the amygdala
Q30560626Synaptic encoding of fear extinction in mPFC-amygdala circuits
Q37196281Synaptic mechanisms underlying strong reciprocal connectivity between the medial prefrontal cortex and basolateral amygdala
Q37407557Synaptic protein degradation as a mechanism in memory reorganization
Q46627176Synaptology of ventral CA1 and subiculum projections to the basomedial nucleus of the amygdala in the mouse: relation to GABAergic interneurons
Q64074980Systemic Cellular Activation Mapping of an Extinction-Impaired Animal Model
Q47727311Target-specific vulnerability of excitatory synapses leads to deficits in associative memory in a model of intellectual disorder.
Q37013398Thalamic Contribution to Cortical Processing of Taste and Expectation
Q35210765The Class I HDAC inhibitor RGFP963 enhances consolidation of cued fear extinction
Q92152797The Conditions under Which Consolidation of Serial-Order Conditioned Fear Requires De Novo Protein Synthesis in the Basolateral Amygdala Complex
Q64263267The Divergent Effects of CDPPB and Cannabidiol on Fear Extinction and Anxiety in a Predator Scent Stress Model of PTSD in Rats
Q47781311The L-type voltage-gated calcium channel CaV1.2 mediates fear extinction and modulates synaptic tone in the lateral amygdala
Q38629075The Origins and Organization of Vertebrate Pavlovian Conditioning
Q37816219The Potent Effect of Environmental Context on Relapse to Alcohol-Seeking After Extinction
Q26776203The Role of the Medial Prefrontal Cortex in the Conditioning and Extinction of Fear
Q39057354The Sensory Neocortex and Associative Memory
Q30462832The age of anxiety: role of animal models of anxiolytic action in drug discovery
Q38082742The amygdala and medial prefrontal cortex: partners in the fear circuit
Q26851538The amygdala: securing pleasure and avoiding pain
Q47991465The basolateral amygdala is critical for learning about neutral stimuli in the presence of danger, and the perirhinal cortex is critical in the absence of danger.
Q42879305The basolateral amygdala is critical for the acquisition and extinction of associations between a neutral stimulus and a learned danger signal but not between two neutral stimuli.
Q34540999The blockade of the transient receptor potential vanilloid type 1 and fatty acid amide hydrolase decreases symptoms and central sequelae in the medial prefrontal cortex of neuropathic rats
Q30372063The contextual brain: implications for fear conditioning, extinction and psychopathology
Q47900609The dynamic nature of fear engrams in the basolateral amygdala
Q30414743The ecology of human fear: survival optimization and the nervous system
Q42626810The effect of chronic administration of corticosterone on anxiety- and depression-like behavior and the expression of GABA-A receptor alpha-2 subunits in brain structures of low- and high-anxiety rats.
Q39298397The fear circuit revisited: contributions of the basal amygdala nuclei to conditioned fear
Q26822528The hippocampal-prefrontal pathway: the weak link in psychiatric disorders?
Q34357064The hypocretin/orexin system mediates the extinction of fear memories.
Q34720448The influence of acute stress on the regulation of conditioned fear
Q60713018The neurobiology of anxiety disorders: brain imaging, genetics, and psychoneuroendocrinology
Q26786672The role of Neuropeptide Y in fear conditioning and extinction
Q64329876The role of prefrontal-subcortical circuitry in negative bias in anxiety: Translational, developmental and treatment perspectives
Q26779278The role of serotonin 5-HT2A receptors in memory and cognition
Q89357284The role of the basolateral amygdala and infralimbic cortex in (re)learning extinction
Q34352202Thy1-expressing neurons in the basolateral amygdala may mediate fear inhibition
Q64265300Tinbergen's challenge for the neuroscience of behavior
Q48308362Transgenic labeling of higher order neuronal circuits linked to phospholipase C‐β2–expressing taste bud cells in medaka fish
Q37438375Transitions in infant learning are modulated by dopamine in the amygdala
Q36129780Uncertainty-Dependent Extinction of Fear Memory in an Amygdala-mPFC Neural Circuit Model.
Q47887702Using c-Jun to identify fear extinction learning-specific patterns of neural activity that are affected by single prolonged stress
Q30437445Variation in serotonin transporter expression modulates fear-evoked hemodynamic responses and theta-frequency neuronal oscillations in the amygdala
Q34722583Ventral hippocampal kappa opioid receptors mediate the renewal of fear following extinction in the rat
Q50113136Vigilance-Associated Gamma Oscillations Coordinate the Ensemble Activity of Basolateral Amygdala Neurons
Q57302141WHEN SCIENTIFIC PARADIGMS LEAD TO TUNNEL VISION: LESSONS FROM THE STUDY OF FEAR
Q35914998Wired for behaviors: from development to function of innate limbic system circuitry
Q35160493mGluR1, but not mGluR5, activates feed-forward inhibition in the medial prefrontal cortex to impair decision making
Q36894465mGluR2/3 in the Lateral Amygdala is Required for Fear Extinction: Cortical Input Synapses onto the Lateral Amygdala as a Target Site of the mGluR2/3 Action.
Q36303815p300/CBP-associated factor selectively regulates the extinction of conditioned fear