Immature T-cell clustering and efficient differentiation require the polarity protein Scribble

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Immature T-cell clustering and efficient differentiation require the polarity protein Scribble is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2011PNAS..108.1116P
P356DOI10.1073/PNAS.1018224108
P932PMC publication ID3024664
P698PubMed publication ID21189299
P5875ResearchGate publication ID49712691

P2093author name stringTony Pawson
Kelly A Pike
Sarang Kulkarni
P2860cites workRAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1Q24307232
A focused and efficient genetic screening strategy in the mouse: identification of mutations that disrupt cortical developmentQ24798758
Integrin avidity regulation: are changes in affinity and conformation underemphasized?Q28205914
Disruption of scribble (Scrb1) causes severe neural tube defects in the circletail mouseQ28218970
The LFA-1-associated molecule PTA-1 (CD226) on T cells forms a dynamic molecular complex with protein 4.1G and human discs largeQ28261201
Scrib controls Cdc42 localization and activity to promote cell polarization during astrocyte migrationQ28571938
Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage developmentQ28584820
Plat-E: an efficient and stable system for transient packaging of retrovirusesQ29614830
NOS1AP associates with Scribble and regulates dendritic spine development.Q30355146
A synaptic basis for paracrine interleukin-2 signaling during homotypic T cell interactionQ30654313
Domains controlling cell polarity and proliferation in the Drosophila tumor suppressor ScribbleQ36322896
Positive and negative selection of T cell receptor V beta domains controlled by distinct cell populations in the thymusQ36357142
Mapping precursor movement through the postnatal thymus reveals specific microenvironments supporting defined stages of early lymphoid developmentQ36369382
Journey through the thymus: stromal guides for T-cell development and selectionQ36402237
Thymic microenvironments for T cell differentiation and selection.Q36426803
Kinetics of T cell receptor beta, gamma, and delta rearrangements during adult thymic development: T cell receptor rearrangements are present in CD44(+)CD25(+) Pro-T thymocytesQ36525985
Polarity regulators and the control of epithelial architecture, cell migration, and tumorigenesis.Q36881687
Upsides and downsides to polarity and asymmetric cell division in leukemia.Q37333623
In a radiation chimaera, host H–2 antigens determine immune responsiveness of donor cytotoxic cellsQ40658124
Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro.Q40683787
Kinetics of steady-state differentiation and mapping of intrathymic-signaling environments by stem cell transplantation in nonirradiated miceQ41854796
The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblastsQ42497218
The leading edge during dorsal closure as a model for epithelial plasticity: Pak is required for recruitment of the Scribble complex and septate junction formation.Q43054618
LFA-1 affinity regulation is necessary for the activation and proliferation of naive T cellsQ43136846
Deficient T cell fate specification in mice with an induced inactivation of Notch1.Q45345200
The role of Notch and IL-7 signaling in early thymocyte proliferation and differentiation.Q52054979
Thymocyte-thymocyte interaction for efficient positive selection and maturation of CD4 T cells.Q53612045
The two poles of the lymphocyte: specialized cell compartments for migration and recruitmentQ54966424
A Network of PDZ-Containing Proteins Regulates T Cell Polarity and Morphology during Migration and Immunological Synapse FormationQ60489489
Involvement of E-cadherin in thymus organogenesis and thymocyte maturationQ73167513
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)1116-1121
P577publication date2010-12-28
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleImmature T-cell clustering and efficient differentiation require the polarity protein Scribble
P478volume108

Reverse relations

cites work (P2860)
Q36269004Asymmetric Cell Division in T Lymphocyte Fate Diversification
Q36078235Asymmetric cell division during T cell development controls downstream fate
Q54479992Divergent lymphocyte signalling revealed by a powerful new tool for analysis of time-lapse microscopy.
Q58582714Influence of Scribble polarity complex on hematopoiesis and leukemia - a matter of where, when and how
Q41337629Lethal giant larvae-1 deficiency enhances the CD8(+) effector T-cell response to antigen challenge in vivo.
Q30826108Ligand-induced Epitope Masking: DISSOCIATION OF INTEGRIN α5β1-FIBRONECTIN COMPLEXES ONLY BY MONOCLONAL ANTIBODIES WITH AN ALLOSTERIC MODE OF ACTION.
Q49029848Measurement of lymphocyte aggregation by flow cytometry-physiological implications in chronic lymphocytic leukemia
Q36183371Polarity and lymphocyte fate determination
Q37489543Polarity gene discs large homolog 1 regulates the generation of memory T cells
Q38189357Polarized cells, polarized views: asymmetric cell division in hematopoietic cells.
Q41619411Pseudorabies virus triggers glycoprotein gE-mediated ERK1/2 activation and ERK1/2-dependent migratory behavior in T cells
Q44016137Regulation of asymmetric cell division and polarity by Scribble is not required for humoral immunity.
Q38873857Scribble acts as an oncogene in Eμ-myc-driven lymphoma
Q42378868TC-PTP regulates the IL-7 transcriptional response during murine early T cell development
Q51768160The cell fate determinant Scribble is required for maintenance of hematopoietic stem cell function.

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