| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2011PNAS..10811458S |
| P356 | DOI | 10.1073/PNAS.1017474108 |
| P932 | PMC publication ID | 3136287 |
| P698 | PubMed publication ID | 21709232 |
| P5875 | ResearchGate publication ID | 51253703 |
| P50 | author | Dennis Discher | Q42675760 |
| P2093 | author name string | Joe Swift | |
| Jae-Won Shin | |||
| Kyle R Spinler | |||
| P2860 | cites work | Differential localization of myosin-II isozymes in human cultured cells and blood cells | Q24312703 |
| Megakaryocytes derived from embryonic stem cells implicate CalDAG-GEFI in integrin signaling | Q24538576 | ||
| Matrix elasticity directs stem cell lineage specification | Q27860761 | ||
| Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor | Q28183531 | ||
| Bone marrow osteoblastic niche: a new model to study physiological regulation of megakaryopoiesis | Q28472310 | ||
| Defects in cell adhesion and the visceral endoderm following ablation of nonmuscle myosin heavy chain II-A in mice | Q28511656 | ||
| Osteoblastic cells regulate the haematopoietic stem cell niche | Q29615007 | ||
| Properties of the demarcation membrane system in living rat megakaryocytes. | Q30476424 | ||
| Infusion of mature megakaryocytes into mice yields functional platelets | Q30497158 | ||
| Myosin II contributes to cell-scale actin network treadmilling through network disassembly | Q30540043 | ||
| Mutations in MYH9 result in the May-Hegglin anomaly, and Fechtner and Sebastian syndromes. The May-Heggllin/Fechtner Syndrome Consortium | Q33333965 | ||
| Mutation of MYH9, encoding non-muscle myosin heavy chain A, in May-Hegglin anomaly. | Q33333969 | ||
| Platelet-derived growth factor enhances ex vivo expansion of megakaryocytic progenitors from human cord blood | Q33337997 | ||
| Carboplatin and paclitaxel interact antagonistically in a megakaryoblast cell line--a potential mechanism for paclitaxel-mediated sparing of carboplatin-induced thrombocytopenia. | Q33339216 | ||
| Defective expression of GPIb/IX/V complex in platelets from patients with May-Hegglin anomaly and Sebastian syndrome. | Q33344163 | ||
| Prophylactic platelet transfusions: which dose is the best dose? A review of the literature | Q33349172 | ||
| The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway | Q33374705 | ||
| Abnormal megakaryocyte morphology and proplatelet formation in mice with megakaryocyte-restricted MYH9 inactivation. | Q33381908 | ||
| Proplatelet formation deficit and megakaryocyte death contribute to thrombocytopenia in Myh9 knockout mice. | Q33391298 | ||
| Adhesively-tensed cell membranes: lysis kinetics and atomic force microscopy probing | Q34183247 | ||
| Cytoskeletal mechanics of proplatelet maturation and platelet release. | Q34317068 | ||
| Inhibition of "self" engulfment through deactivation of myosin-II at the phagocytic synapse between human cells | Q34760500 | ||
| Myosin-IIA heavy-chain phosphorylation regulates the motility of MDA-MB-231 carcinoma cells | Q35942363 | ||
| Blood platelets are assembled principally at the ends of proplatelet processes produced by differentiated megakaryocytes | Q36313419 | ||
| On the role of myosin-II in cytokinesis: division of Dictyostelium cells under adhesive and nonadhesive conditions | Q36949652 | ||
| Regulation of alpha 2 integrin gene expression in cells with megakaryocytic features: a common theme of three necessary elements | Q38508347 | ||
| Receptor heterodimerization: essential mechanism for platelet-derived growth factor-induced epidermal growth factor receptor transactivation | Q39528062 | ||
| Myosin is an in vivo substrate of the protein tyrosine phosphatase (SHP-1) after mIgM cross-linking | Q40653756 | ||
| Expression and function of the collagen receptor GPVI during megakaryocyte maturation. | Q43559487 | ||
| Micropipette aspiration of guinea pig megakaryocytes: absence of fragmentation and dependence on maturation stage | Q46232431 | ||
| Bone marrow-derived human mesenchymal stem cells become quiescent on soft substrates but remain responsive to chemical or mechanical stimuli | Q47420367 | ||
| Interrelation between polyploidization and megakaryocyte differentiation: a gene profiling approach. | Q51999245 | ||
| Disruption of the Dictyostelium myosin heavy chain gene by homologous recombination. | Q52256480 | ||
| Dynamic Visualization of Thrombopoiesis Within Bone Marrow | Q58450371 | ||
| Human platelets produced in nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice upon transplantation of human cord blood CD34+ cells are functionally active in an ex vivo flow model of thrombosis | Q58481423 | ||
| Immunofluorescence characterization of key extracellular matrix proteins in murine bone marrow in situ | Q74258250 | ||
| Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors | Q81015137 | ||
| P433 | issue | 28 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 11458-11463 | |
| P577 | publication date | 2011-06-27 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Myosin-II inhibition and soft 2D matrix maximize multinucleation and cellular projections typical of platelet-producing megakaryocytes | |
| P478 | volume | 108 |
| Q38568042 | A journey to produce platelets in vitro |
| Q41480921 | A new path to platelet production through matrix sensing. |
| Q34562161 | Absence of platelet phenotype in mice lacking the motor protein myosin Va |
| Q35981814 | Blood and immune cell engineering: Cytoskeletal contractility and nuclear rheology impact cell lineage and localization: Biophysical regulation of hematopoietic differentiation and trafficking |
| Q39909113 | Cdc42-dependent F-actin dynamics drive structuration of the demarcation membrane system in megakaryocytes |
| Q84603820 | Cell culture: Soft gels select tumorigenic cells |
| Q38074224 | Challenges and promises for the development of donor-independent platelet transfusions |
| Q38213259 | Combining insoluble and soluble factors to steer stem cell fate. |
| Q30528218 | Crawling from soft to stiff matrix polarizes the cytoskeleton and phosphoregulates myosin-II heavy chain |
| Q27322516 | Defects in TRPM7 channel function deregulate thrombopoiesis through altered cellular Mg(2+) homeostasis and cytoskeletal architecture |
| Q30452421 | Enhancing the efficacy of drug-loaded nanocarriers against brain tumors by targeted radiation therapy. |
| Q38187494 | Ex vivo production of platelets from stem cells |
| Q58776914 | Hematopoietic stem cell loss and hematopoietic failure in severe aplastic anemia is driven by macrophages and aberrant podoplanin expression |
| Q41510461 | Hyaluronan based hydrogels provide an improved model to study megakaryocyte-matrix interactions |
| Q58883947 | Hyaluronic acid matrices show matrix stiffness in 2D and 3D dictates cytoskeletal order and myosin-II phosphorylation within stem cells |
| Q37586976 | Label-free mass spectrometry exploits dozens of detected peptides to quantify lamins in wildtype and knockdown cells. |
| Q36916403 | Local 3D matrix confinement determines division axis through cell shape |
| Q33424186 | Manipulating megakaryocytes to manufacture platelets ex vivo |
| Q33726992 | Matrix Mechanosensing: From Scaling Concepts in 'Omics Data to Mechanisms in the Nucleus, Regeneration, and Cancer |
| Q30536938 | Matrix stiffness reverses the effect of actomyosin tension on cell proliferation |
| Q37661138 | Mechanobiology of bone marrow stem cells: from myosin-II forces to compliance of matrix and nucleus in cell forms and fates. |
| Q38777454 | Megakaryocyte Polyploidization and Proplatelet Formation in Low-Attachment Conditions |
| Q36778744 | Megakaryocytic Maturation in Response to Shear Flow Is Mediated by the Activator Protein 1 (AP-1) Transcription Factor via Mitogen-activated Protein Kinase (MAPK) Mechanotransduction |
| Q57376195 | Moving from static to dynamic complexity in hydrogel design |
| Q57214406 | Multi-channel silk sponge mimicking bone marrow vascular niche for platelet production |
| Q33418701 | Myosin-II repression favors pre/proplatelets but shear activation generates platelets and fails in macrothrombocytopenia |
| Q30511966 | Nonmuscle myosin II exerts tension but does not translocate actin in vertebrate cytokinesis. |
| Q37686106 | Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation |
| Q91869736 | Perspective: Biophysical regulation of cancerous and normal blood cell lineages in hematopoietic malignancies |
| Q34209300 | Platelet bioreactor-on-a-chip |
| Q35252648 | Programmable 3D silk bone marrow niche for platelet generation ex vivo and modeling of megakaryopoiesis pathologies. |
| Q36185474 | Proposed megakaryocytic regulon of p53: the genes engaged to control cell cycle and apoptosis during megakaryocytic differentiation |
| Q39384298 | RUNX1-induced silencing of non-muscle myosin heavy chain IIB contributes to megakaryocyte polyploidization |
| Q38784723 | Recent developments in ex vivo platelet production. |
| Q43068017 | Reduced matrix rigidity promotes neonatal cardiomyocyte dedifferentiation, proliferation and clonal expansion |
| Q33409693 | RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generation |
| Q34671302 | Road blocks in making platelets for transfusion |
| Q40402310 | Role of tumor suppressor p53 in megakaryopoiesis and platelet function |
| Q28081679 | Stem cell mechanobiology: diverse lessons from bone marrow |
| Q33411165 | The abnormal proplatelet formation in MYH9-related macrothrombocytopenia results from an increased actomyosin contractility and is rescued by myosin IIA inhibition. |
| Q48106053 | The role of extracellular matrix stiffness in megakaryocyte and platelet development and function. |
| Q28082685 | The secret life of a megakaryocyte: emerging roles in bone marrow homeostasis control |
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