Neutralization resistance of virological synapse-mediated HIV-1 Infection is regulated by the gp41 cytoplasmic tail

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Neutralization resistance of virological synapse-mediated HIV-1 Infection is regulated by the gp41 cytoplasmic tail is …
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scholarly articleQ13442814

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P356DOI10.1128/JVI.00230-12
P932PMC publication ID3416307
P698PubMed publication ID22553332
P5875ResearchGate publication ID224889060

P2093author name stringRebecca Lee
Ping Chen
James E Robinson
Benjamin K Chen
Natasha D Durham
Chati Zony
Alice W Yewdall
P2860cites workHIV-1 cell to cell transfer across an Env-induced, actin-dependent synapseQ22242967
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Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infectionQ28369033
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Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodiesQ29619015
Sequence of human immunodeficiency virus type 1 (HIV-1) Gag localization and oligomerization monitored with live confocal imaging of a replication-competent, fluorescently tagged HIV-1.Q30480956
Predominant mode of human immunodeficiency virus transfer between T cells is mediated by sustained Env-dependent neutralization-resistant virological synapsesQ30480959
Quantitative 3D video microscopy of HIV transfer across T cell virological synapsesQ30490761
On the steps of cell-to-cell HIV transmission between CD4 T cellsQ30491261
Virological synapse-mediated spread of human immunodeficiency virus type 1 between T cells is sensitive to entry inhibitionQ30493649
Cell-to-cell transfer of HIV-1 via virological synapses leads to endosomal virion maturation that activates viral membrane fusionQ30505286
Tiered categorization of a diverse panel of HIV-1 Env pseudoviruses for assessment of neutralizing antibodiesQ33614365
Functional mimicry of a human immunodeficiency virus type 1 coreceptor by a neutralizing monoclonal antibodyQ33780450
Regulation of human immunodeficiency virus type 1 envelope glycoprotein fusion by a membrane-interactive domain in the gp41 cytoplasmic tailQ33984243
Maturation-induced cloaking of neutralization epitopes on HIV-1 particlesQ34023008
Cell-cell transmission enables HIV-1 to evade inhibition by potent CD4bs directed antibodiesQ34229664
A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1Q34306804
Truncation of the cytoplasmic domain induces exposure of conserved regions in the ectodomain of human immunodeficiency virus type 1 envelope proteinQ34332519
The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120.Q34342352
High level of coreceptor-independent HIV transfer induced by contacts between primary CD4 T cellsQ34550922
Enhanced HIV-1 neutralization by antibody heteroligationQ35735385
HIV cell-to-cell transmission requires the production of infectious virus particles and does not proceed through env-mediated fusion poresQ35826780
Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp120 epitopes induced by receptor bindingQ35845976
Retroviral spread by induction of virological synapsesQ35856741
Dangerous liaisons at the virological synapseQ35877219
Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1.Q36623941
Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 bindingQ36649958
Quantitation of human immunodeficiency virus type 1 infection kineticsQ36686530
Cell-to-cell transmission of human immunodeficiency virus type 1 in the presence of azidothymidine and neutralizing antibodyQ36827670
Regulation of human immunodeficiency virus type 1 Env-mediated membrane fusion by viral protease activityQ36944098
Neutralizing antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine?Q37519312
Toward an antibody-based HIV-1 vaccineQ37613695
Cell-to-Cell Spread of RetrovirusesQ37945208
Bicyclams, a class of potent anti-HIV agents, are targeted at the HIV coreceptor fusin/CXCR-4.Q39438533
A cell-to-cell HIV transfer assay identifies humoral responses with broad neutralization activity.Q39537121
Role of the C-terminal domain of the HIV-1 glycoprotein in cell-to-cell viral transmission between T lymphocytesQ39705226
Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies.Q40429324
Coupling of human immunodeficiency virus type 1 fusion to virion maturation: a novel role of the gp41 cytoplasmic tailQ40579232
Epitope mapping and characterization of a novel CD4-induced human monoclonal antibody capable of neutralizing primary HIV-1 strainsQ40621073
Characterization of CD4-induced epitopes on the HIV type 1 gp120 envelope glycoprotein recognized by neutralizing human monoclonal antibodiesQ40682865
A potent cross-clade neutralizing human monoclonal antibody against a novel epitope on gp41 of human immunodeficiency virus type 1.Q40757568
Maturation-dependent human immunodeficiency virus type 1 particle fusion requires a carboxyl-terminal region of the gp41 cytoplasmic tailQ41898146
A novel gene of HIV-1, vpu, and its 16-kilodalton productQ42656133
Inefficient human immunodeficiency virus replication in mobile lymphocytesQ42957159
Antigp41 antibodies fail to block early events of virological synapses but inhibit HIV spread between T cellsQ58023483
Conformational changes in env oligomer induced by an antibody dependent on the V3 loop baseQ73149534
P433issue14
P921main subjectvirologyQ7215
P304page(s)7484-7495
P577publication date2012-05-02
P1433published inJournal of VirologyQ1251128
P1476titleNeutralization resistance of virological synapse-mediated HIV-1 Infection is regulated by the gp41 cytoplasmic tail
P478volume86

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