| scholarly article | Q13442814 |
| P2093 | author name string | Ji Hoon Yu | |
| Keunsoo Kang | |||
| Lothar Hennighausen | |||
| Bing-Mei Zhu | |||
| Gregory Riedlinger | |||
| P2860 | cites work | Hypoxia and defective apoptosis drive genomic instability and tumorigenesis | Q22242660 |
| Suppression of tumorigenesis by the p53 target PUMA | Q24563144 | ||
| The Bcl-2 apoptotic switch in cancer development and therapy | Q24620437 | ||
| Puma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis induction | Q24677017 | ||
| Upregulation of the NADPH oxidase NOX4 by TGF-beta in hepatocytes is required for its pro-apoptotic activity | Q28565751 | ||
| NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart. | Q34100612 | ||
| Fatal hepatitis mediated by tumor necrosis factor TNFalpha requires caspase-8 and involves the BH3-only proteins Bid and Bim. | Q34124538 | ||
| Nox4 NADPH oxidase-derived reactive oxygen species, via endogenous carbon monoxide, promote survival of brain endothelial cells during TNF-α-induced apoptosis | Q34597540 | ||
| The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91(phox) mediate hepatic fibrosis in mice | Q34860956 | ||
| PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and mice. | Q34876574 | ||
| Destruction of tumor vasculature and abated tumor growth upon VEGF blockade is driven by proapoptotic protein Bim in endothelial cells. | Q35102284 | ||
| The transcription factors signal transducer and activator of transcription 5A (STAT5A) and STAT5B negatively regulate cell proliferation through the activation of cyclin-dependent kinase inhibitor 2b (Cdkn2b) and Cdkn1a expression | Q35153143 | ||
| A key role for NOX4 in epithelial cell death during development of lung fibrosis. | Q35185363 | ||
| Loss of sexually dimorphic liver gene expression upon hepatocyte-specific deletion of Stat5a-Stat5b locus | Q35764581 | ||
| Normal growth and development in the absence of hepatic insulin-like growth factor I | Q36394699 | ||
| Interpretation of cytokine signaling through the transcription factors STAT5A and STAT5B | Q36672274 | ||
| Loss of STAT5 causes liver fibrosis and cancer development through increased TGF-{beta} and STAT3 activation. | Q37273279 | ||
| JNK1-dependent PUMA expression contributes to hepatocyte lipoapoptosis | Q37446730 | ||
| Bim is a suppressor of Myc-induced mouse B cell leukemia | Q37647369 | ||
| BID, BIM, and PUMA are essential for activation of the BAX- and BAK-dependent cell death program | Q38269004 | ||
| Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice. | Q39651056 | ||
| Transforming growth factor-beta induces senescence in hepatocellular carcinoma cells and inhibits tumor growth. | Q39687638 | ||
| Palmitoleate attenuates palmitate-induced Bim and PUMA up-regulation and hepatocyte lipoapoptosis | Q39731721 | ||
| SOCS1 links cytokine signaling to p53 and senescence | Q39764206 | ||
| Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes. | Q40057699 | ||
| STAT5A is epigenetically silenced by the tyrosine kinase NPM1-ALK and acts as a tumor suppressor by reciprocally inhibiting NPM1-ALK expression | Q40070793 | ||
| PUMA suppresses intestinal tumorigenesis in mice | Q40620684 | ||
| Reduced nicotinamide adenine dinucleotide phosphate oxidase 2 plays a key role in stellate cell activation and liver fibrogenesis in vivo | Q42084575 | ||
| The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence. | Q42123048 | ||
| Tumor necrosis factor α sensitizes primary murine hepatocytes to Fas/CD95-induced apoptosis in a Bim- and Bid-dependent manner | Q43718895 | ||
| Growth-hormone-induced signal transducer and activator of transcription 5 signaling causes gigantism, inflammation, and premature death but protects mice from aggressive liver cancer | Q58450503 | ||
| PUMA expression is significantly reduced in human cutaneous melanomas | Q64378968 | ||
| Loss of signal transducer and activator of transcription 5 leads to hepatosteatosis and impaired liver regeneration | Q80638835 | ||
| NOX1/nicotinamide adenine dinucleotide phosphate, reduced form (NADPH) oxidase promotes proliferation of stellate cells and aggravates liver fibrosis induced by bile duct ligation | Q84208245 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | reactive oxygen species | Q424361 |
| P304 | page(s) | 2375-2386 | |
| P577 | publication date | 2012-12-01 | |
| P1433 | published in | Hepatology | Q15724398 |
| P1476 | title | The liver-specific tumor suppressor STAT5 controls expression of the reactive oxygen species-generating enzyme NOX4 and the proapoptotic proteins PUMA and BIM in mice | |
| P478 | volume | 56 |
| Q92497909 | Adipocyte JAK2 mediates spontaneous metabolic liver disease and hepatocellular carcinoma |
| Q90069496 | CPAP promotes angiogenesis and metastasis by enhancing STAT3 activity |
| Q28550623 | Chemical and Hormonal Effects on STAT5b-Dependent Sexual Dimorphism of the Liver Transcriptome |
| Q34730646 | Evolution of hepatic steatosis to fibrosis and adenoma formation in liver-specific growth hormone receptor knockout mice |
| Q37227925 | GRAM domain-containing protein 1A (GRAMD1A) promotes the expansion of hepatocellular carcinoma stem cell and hepatocellular carcinoma growth through STAT5 |
| Q41361264 | Hepatic Deletion of Janus Kinase 2 Counteracts Oxidative Stress in Mice. |
| Q87869622 | IL-15 regulates Bcl-2 family members Bim and Mcl-1 through JAK/STAT and PI3K/AKT pathways in T cells |
| Q46430962 | Janus Kinase 2 (JAK2) Dissociates Hepatosteatosis from Hepatocellular Carcinoma in Mice. |
| Q34185231 | Modeling progressive non-alcoholic fatty liver disease in the laboratory mouse |
| Q38599090 | NADPH Oxidases in Chronic Liver Diseases |
| Q46679237 | NOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells |
| Q38177820 | Oxidative metabolism in cancer: A STAT affair? |
| Q33904328 | Oxidative stress and hepatic Nox proteins in chronic hepatitis C and hepatocellular carcinoma |
| Q64094674 | PEST-containing nuclear protein regulates cell proliferation, migration, and invasion in lung adenocarcinoma |
| Q40979812 | Quercetin Reverses Rat Liver Preneoplastic Lesions Induced by Chemical Carcinogenesis. |
| Q49895909 | Reply (to LTE HEP-17-2075). |
| Q45258708 | Reply: To PMID 21725989. |
| Q42153537 | STAT5 triggers BCR-ABL1 mutation by mediating ROS production in chronic myeloid leukaemia |
| Q37705443 | The NADPH oxidase NOX4 represses epithelial to amoeboid transition and efficient tumour dissemination. |
| Q89842501 | Unphosphorylated STAT3 in heterochromatin formation and tumor suppression in lung cancer |
| Q36754884 | p53-upregulated-modulator-of-apoptosis (PUMA) deficiency affects food intake but does not impact on body weight or glucose homeostasis in diet-induced obesity |
| Q35550985 | {2-[1-(3-Methoxycarbonylmethyl-1H-indol-2-yl)-1-methyl-ethyl]-1H-indol-3-yl}-acetic Acid Methyl Ester Inhibited Hepatocellular Carcinoma Growth in Bel-7402 Cells and Its Resistant Variants by Activation of NOX4 and SIRT3. |
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