| scholarly article | Q13442814 |
| P50 | author | Boris Hinz | Q40441058 |
| Botond Banfi | Q57439094 | ||
| P2093 | author name string | Jack L Arbiser | |
| Karl-Heinz Krause | |||
| Jean-Claude Pache | |||
| Yves Donati | |||
| Olivier Basset | |||
| Cecile Guichard | |||
| Olivier Preynat-Seauve | |||
| Constance Barazzone-Argiroffo | |||
| Stephanie Carnesecchi | |||
| Christine Deffert | |||
| P2860 | cites work | Identification of renox, an NAD(P)H oxidase in kidney | Q22254385 |
| Targeted injury of type II alveolar epithelial cells induces pulmonary fibrosis | Q42002715 | ||
| c-Jun N-terminal kinase 1 is required for the development of pulmonary fibrosis | Q43156994 | ||
| Transforming growth factor-beta1 gene polymorphisms are associated with disease progression in idiopathic pulmonary fibrosis. | Q44440456 | ||
| Antioxidant therapy for idiopathic pulmonary fibrosis | Q46818803 | ||
| Transforming growth factor (TGF)-beta1 stimulates pulmonary fibrosis and inflammation via a Bax-dependent, bid-activated pathway that involves matrix metalloproteinase-12. | Q50232161 | ||
| NOX-4 is expressed in thickened pulmonary arteries in idiopathic pulmonary fibrosis | Q59489621 | ||
| Isolation and primary culture of murine alveolar type II cells | Q70999865 | ||
| P21Waf1/Cip1/Sdi1 and p53 expression in association with DNA strand breaks in idiopathic pulmonary fibrosis | Q71395532 | ||
| Abrogation of bleomycin-induced epithelial apoptosis and lung fibrosis by captopril or by a caspase inhibitor | Q73992884 | ||
| A p38 MAPK inhibitor, FR-167653, ameliorates murine bleomycin-induced pulmonary fibrosis | Q74286472 | ||
| Alveolar epithelial cell death adjacent to underlying myofibroblasts in advanced fibrotic human lung | Q77649804 | ||
| Discrimination of C57BL/6J Rj and 129S2/SvPasCrl inbred mouse strains by use of simple sequence length polymorphisms | Q79892982 | ||
| Poly(ADP-ribose) polymerase-1 (PARP-1) controls lung cell proliferation and repair after hyperoxia-induced lung damage | Q80491319 | ||
| Hydrogen peroxide is a diffusible paracrine signal for the induction of epithelial cell death by activated myofibroblasts | Q81694298 | ||
| NAD(P)H oxidase Nox-4 mediates 7-ketocholesterol-induced endoplasmic reticulum stress and apoptosis in human aortic smooth muscle cells | Q24559719 | ||
| Cellular and molecular mechanisms of fibrosis | Q24648892 | ||
| The absence of reactive oxygen species production protects mice against bleomycin-induced pulmonary fibrosis | Q24803487 | ||
| The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology | Q27860991 | ||
| Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy | Q28200083 | ||
| Myofibroblasts and mechano-regulation of connective tissue remodelling | Q28216468 | ||
| High-dose acetylcysteine in idiopathic pulmonary fibrosis | Q28283438 | ||
| NADPH oxidase-1 plays a crucial role in hyperoxia-induced acute lung injury in mice | Q28588550 | ||
| How cells read TGF-beta signals | Q29619993 | ||
| NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases | Q33834313 | ||
| NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGFbeta1-induced fibroblast differentiation into myofibroblasts. | Q34415231 | ||
| Proapoptotic Bid is required for pulmonary fibrosis | Q34448290 | ||
| NAD(P)H oxidase 4 mediates transforming growth factor-beta1-induced differentiation of cardiac fibroblasts into myofibroblasts | Q34453246 | ||
| Oxidative stress in pulmonary fibrosis: a possible role for redox modulatory therapy | Q36128020 | ||
| A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation | Q36216808 | ||
| Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosis | Q36399732 | ||
| Evolving concepts of apoptosis in idiopathic pulmonary fibrosis | Q36493966 | ||
| Formation and function of the myofibroblast during tissue repair | Q36735389 | ||
| Innate host defense: Nox and Duox on phox's tail | Q36835213 | ||
| TGF-beta, Smad3 and the process of progressive fibrosis. | Q36883832 | ||
| TGF-beta signaling: a tale of two responses | Q36923146 | ||
| The bleomycin animal model: a useful tool to investigate treatment options for idiopathic pulmonary fibrosis? | Q36970923 | ||
| Transforming growth factor-beta activation in the lung: focus on fibrosis and reactive oxygen species | Q36981625 | ||
| Murine models of pulmonary fibrosis. | Q36997546 | ||
| Antioxidants as potential therapeutics for lung fibrosis | Q36999926 | ||
| How the Smads regulate transcription | Q37025325 | ||
| Epithelial cell apoptosis and lung remodeling. | Q37046829 | ||
| Dynamic control of TGF-beta signaling and its links to the cytoskeleton | Q37122606 | ||
| Fulvene-5 potently inhibits NADPH oxidase 4 and blocks the growth of endothelial tumors in mice. | Q37286610 | ||
| NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury. | Q37345265 | ||
| Nox proteins in signal transduction | Q37392163 | ||
| First in class, potent, and orally bioavailable NADPH oxidase isoform 4 (Nox4) inhibitors for the treatment of idiopathic pulmonary fibrosis | Q39645010 | ||
| Intracellular expression of reactive oxygen species-generating NADPH oxidase NOX4 in normal and cancer thyroid tissues | Q39944407 | ||
| NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation. | Q40133141 | ||
| P433 | issue | 3 | |
| P921 | main subject | pulmonary fibrosis | Q32446 |
| cell death | Q2383867 | ||
| P304 | page(s) | 607-619 | |
| P577 | publication date | 2011-05-25 | |
| P1433 | published in | Antioxidants & Redox Signaling | Q4775078 |
| P1476 | title | A key role for NOX4 in epithelial cell death during development of lung fibrosis | |
| P478 | volume | 15 |
| Q92572647 | 7-Ketocholesterol in disease and aging |
| Q39021776 | A far-upstream AP-1/Smad binding box regulates human NOX4 promoter activation by transforming growth factor-β |
| Q93336387 | Abrogation of transforming growth factor-β-induced tissue fibrosis in mice with a global genetic deletion of Nox4 |
| Q39234400 | Activation of calcium signaling through Trpv1 by nNOS and peroxynitrite as a key trigger of skeletal muscle hypertrophy |
| Q91960927 | Age-dependent dysregulation of redox genes may contribute to fibrotic pulmonary disease susceptibility |
| Q36105254 | BARD1 mediates TGF-β signaling in pulmonary fibrosis. |
| Q38140574 | Beneficial role of vitamin D3 in the prevention of certain respiratory diseases |
| Q46621289 | Bimodal role of NADPH oxidases in the regulation of biglycan-triggered IL-1β synthesis. |
| Q26991619 | Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system |
| Q97527734 | CSF-1 in Osteocytes Inhibits Nox4-mediated Oxidative Stress and Promotes Normal Bone Homeostasis |
| Q34991150 | Chronic administration of Δ9-tetrahydrocannabinol induces intestinal anti-inflammatory microRNA expression during acute simian immunodeficiency virus infection of rhesus macaques |
| Q47901277 | Correlation between plasminogen activator inhibitor-1 (PAI-1) promoter 4G/5G polymorphism and metabolic/proinflammatory factors in polycystic ovary syndrome |
| Q28487910 | Curcumin nanoparticles ameliorate ICAM-1 expression in TNF-α-treated lung epithelial cells through p47 (phox) and MAPKs/AP-1 pathways |
| Q54318425 | Deficiency in the NADPH oxidase 4 predisposes towards diet-induced obesity. |
| Q35984159 | Discovery of GSK2795039, a Novel Small Molecule NADPH Oxidase 2 Inhibitor |
| Q34372816 | Dual oxidase 2 in lung epithelia is essential for hyperoxia-induced acute lung injury in mice |
| Q36059818 | Ebselen and congeners inhibit NADPH oxidase 2-dependent superoxide generation by interrupting the binding of regulatory subunits |
| Q37359689 | Effect of Xinjiang Uyghur Vernonia anthelmintica Willd Injection Treatment with Silicosis Fibrosis |
| Q35580488 | Epithelial cell mitochondrial dysfunction and PINK1 are induced by transforming growth factor-beta1 in pulmonary fibrosis |
| Q33761211 | European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS). |
| Q26861119 | Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement |
| Q38057744 | From form to function: the role of Nox4 in the cardiovascular system |
| Q55211516 | Gefitinib Inhibits Bleomycin-Induced Pulmonary Fibrosis via Alleviating the Oxidative Damage in Mice. |
| Q37110889 | Glutathione peroxidase 3 localizes to the epithelial lining fluid and the extracellular matrix in interstitial lung disease |
| Q26852800 | Host responses in tissue repair and fibrosis |
| Q35895695 | IGF-I increases the expression of fibronectin by Nox4-dependent Akt phosphorylation in renal tubular epithelial cells |
| Q37386864 | Imatinib mesylate causes genome-wide transcriptional changes in systemic sclerosis fibroblasts in vitro. |
| Q30604902 | Innate immunity. A Spaetzle-like role for nerve growth factor β in vertebrate immunity to Staphylococcus aureus |
| Q46864542 | Is Nox4 a key regulator of the activated state of fibroblasts in systemic sclerosis? |
| Q36650779 | Lung extracellular matrix and redox regulation |
| Q34793732 | Macrophage-specific NOX2 contributes to the development of lung emphysema through modulation of SIRT1/MMP-9 pathways |
| Q36012612 | Mechanisms of pulmonary fibrosis: role of activated myofibroblasts and NADPH oxidase |
| Q40984750 | Metformin attenuates lung fibrosis development via NOX4 suppression |
| Q38946134 | Methods for Implant Acceptance and Wound Healing: Material Selection and Implant Location Modulate Macrophage and Fibroblast Phenotypes |
| Q36237168 | Molecular and cellular mechanisms of pulmonary fibrosis |
| Q38543053 | Molecular and cellular mechanisms of the inhibitory effects of ACE-2/ANG1-7/Mas axis on lung injury |
| Q27022840 | Myofibroblasts |
| Q64376400 | NADPH Oxidase 4 Regulates Inflammation in Ischemic Heart Failure: Role of Soluble Epoxide Hydrolase |
| Q90028399 | NADPH Oxidase Inhibition in Fibrotic Pathologies |
| Q37479906 | NADPH oxidase 4 deficiency increases tubular cell death during acute ischemic reperfusion injury. |
| Q46243640 | NADPH oxidase 4 mediates ROS production in radiation-induced senescent cells and promotes migration of inflammatory cells. |
| Q41083520 | NADPH oxidase 4-derived H2O2 promotes aberrant retinal neovascularization via activation of VEGF receptor 2 pathway in oxygen-induced retinopathy |
| Q36339543 | NADPH oxidase NOX2 defines a new antagonistic role for reactive oxygen species and cAMP/PKA in the regulation of insulin secretion. |
| Q34438060 | NADPH oxidase NOX4 mediates stellate cell activation and hepatocyte cell death during liver fibrosis development. |
| Q37541098 | NADPH oxidase-dependent redox signaling in TGF-β-mediated fibrotic responses. |
| Q27027435 | NADPH oxidases in lung health and disease |
| Q36426109 | NADPH-oxidase 4 protects against kidney fibrosis during chronic renal injury |
| Q35977261 | NOX Modifiers-Just a Step Away from Application in the Therapy of Airway Inflammation? |
| Q38009734 | NOX enzymes: potential target for the treatment of acute lung injury |
| Q37587341 | NOX1 is responsible for cell death through STAT3 activation in hyperoxia and is associated with the pathogenesis of acute respiratory distress syndrome |
| Q88354620 | NOX4 Deletion in Male Mice Exacerbates the Effect of Ethanol on Trabecular Bone and Osteoblastogenesis |
| Q92756602 | NOX4 modulates macrophage phenotype and mitochondrial biogenesis in asbestosis |
| Q37548406 | NOX4-dependent fatty acid oxidation promotes NLRP3 inflammasome activation in macrophages |
| Q42160197 | NOX4-derived reactive oxygen species limit fibrosis and inhibit proliferation of vascular smooth muscle cells in diabetic atherosclerosis |
| Q26862779 | Neuroprotection after stroke by targeting NOX4 as a source of oxidative stress |
| Q34432217 | New therapeutic targets in idiopathic pulmonary fibrosis. Aiming to rein in runaway wound-healing responses |
| Q38092960 | Nox4 and diabetic nephropathy: with a friend like this, who needs enemies? |
| Q28387033 | Nox4 and redox signaling mediate TGF-β-induced endothelial cell apoptosis and phenotypic switch |
| Q36252551 | Nox4 involvement in TGF-beta and SMAD3-driven induction of the epithelial-to-mesenchymal transition and migration of breast epithelial cells. |
| Q35104183 | Oxidants in Acute and Chronic Lung Disease |
| Q90260610 | Oxidative Stress in Pulmonary Fibrosis |
| Q27024861 | Oxidative stress and pulmonary fibrosis |
| Q36829487 | Oxidative stress mediates radiation lung injury by inducing apoptosis. |
| Q46473799 | Pharmacological inhibition of NOX4 ameliorates alcohol-induced liver injury in mice through improving oxidative stress and mitochondrial function |
| Q31133726 | Plumbagin ameliorates diabetic nephropathy via interruption of pathways that include NOX4 signalling |
| Q47774343 | Pulmonary complications post hematopoietic stem cell transplant in dyskeratosis congenita: analysis of oxidative stress in lung fibroblasts. |
| Q54976858 | RIPK3 promotes sepsis-induced acute kidney injury via mitochondrial dysfunction. |
| Q46280873 | ROS Signaling in the Pathogenesis of Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome (ARDS). |
| Q45834311 | Reactive Oxygen Species and NOX Enzymes Are Emerging as Key Players in Cutaneous Wound Repair |
| Q90308685 | Reactive Oxygen Species in Venous Thrombosis |
| Q27024762 | Reactive Oxygen-Related Diseases: Therapeutic Targets and Emerging Clinical Indications |
| Q28077930 | Reactive oxygen species and fibrosis: further evidence of a significant liaison |
| Q26863751 | Recent developments in myofibroblast biology: paradigms for connective tissue remodeling |
| Q26743421 | Redox mechanisms in age-related lung fibrosis |
| Q38202115 | Redox signaling as a therapeutic target to inhibit myofibroblast activation in degenerative fibrotic disease |
| Q26786129 | Redox-fibrosis: Impact of TGFβ1 on ROS generators, mediators and functional consequences |
| Q38138161 | Redox-relevant aspects of the extracellular matrix and its cellular contacts via integrins |
| Q64376891 | Reducing protein oxidation reverses lung fibrosis |
| Q35983620 | Reversal of persistent fibrosis in aging by targeting Nox4-Nrf2 redox imbalance |
| Q28298823 | Role of NADPH oxidase isoforms NOX1, NOX2 and NOX4 in myocardial ischemia/reperfusion injury |
| Q26800143 | Role of NADPH oxidases in the redox biology of liver fibrosis |
| Q36842965 | Role of nicotinamide adenine dinucleotide phosphate-reduced oxidase proteins in Pseudomonas aeruginosa-induced lung inflammation and permeability |
| Q26776555 | Role of redoximiRs in fibrogenesis |
| Q37209545 | Role of type II pneumocyte senescence in radiation-induced lung fibrosis |
| Q39372019 | Secreted protein acidic and rich in cysteine (SPARC) is upregulated by transforming growth factor (TGF)-β and is required for TGF-β-induced hydrogen peroxide production in fibroblasts |
| Q42468959 | Smad-independent pathway involved in transforming growth factor β1-induced Nox4 expression and proliferation of endothelial cells |
| Q36766182 | Strategies Aimed at Nox4 Oxidase Inhibition Employing Peptides from Nox4 B-Loop and C-Terminus and p22 (phox) N-Terminus: An Elusive Target |
| Q37519770 | TGF-β directs trafficking of the epithelial sodium channel ENaC which has implications for ion and fluid transport in acute lung injury |
| Q27022062 | TGF-β signaling in tissue fibrosis: redox controls, target genes and therapeutic opportunities |
| Q35671828 | Targeting NADPH oxidase with a novel dual Nox1/Nox4 inhibitor attenuates renal pathology in type 1 diabetes |
| Q37008372 | Targeting NOX enzymes in pulmonary fibrosis |
| Q99587532 | Targeting cardiac fibrosis in heart failure with preserved ejection fraction: mirage or miracle? |
| Q36112519 | The 1027th target candidate in stroke: Will NADPH oxidase hold up? |
| Q36060782 | The NOX toolbox: validating the role of NADPH oxidases in physiology and disease |
| Q26786969 | The Role of Mitochondrial DNA in Mediating Alveolar Epithelial Cell Apoptosis and Pulmonary Fibrosis |
| Q96126473 | The TSPO-NOX1 axis controls phagocyte-triggered pathological angiogenesis in the eye |
| Q34811358 | The angiotensin-converting enzyme 2/angiotensin (1-7)/Mas axis protects against lung fibroblast migration and lung fibrosis by inhibiting the NOX4-derived ROS-mediated RhoA/Rho kinase pathway |
| Q38261369 | The antioxidant paradox: what are antioxidants and how should they be used in a therapeutic context for cancer |
| Q94460545 | The dietary antioxidant quercetin reduces hallmarks of bleomycin-induced lung fibrogenesis in mice |
| Q30528605 | The liver-specific tumor suppressor STAT5 controls expression of the reactive oxygen species-generating enzyme NOX4 and the proapoptotic proteins PUMA and BIM in mice |
| Q90415361 | The mitochondria in lung fibrosis: friend or foe? |
| Q38858553 | Therapeutic potential of NADPH oxidase 1/4 inhibitors |
| Q51532190 | To Suppress the Radicals We Must Have Biomarkers of Oxidative Stress. |
| Q39010776 | Transforming Growth Factor β1 Function in Airway Remodeling and Hyperresponsiveness. The Missing Link? |
| Q37624843 | Transforming growth factor beta signaling in hepatocytes participates in steatohepatitis through regulation of cell death and lipid metabolism in mice |
| Q35867960 | Transforming growth factor-β1 requires NADPH oxidase 4 for angiogenesis in vitro and in vivo |
| Q37251585 | Trichostatin A, a histone deacetylase inhibitor suppresses NADPH Oxidase 4-Derived Redox Signalling and Angiogenesis |
| Q37013220 | Triptolide mitigates radiation-induced pulmonary fibrosis via inhibition of axis of alveolar macrophages-NOXes-ROS-myofibroblasts |
| Q53307575 | Upregulation of mitochondrial Nox4 mediates TGF-β-induced apoptosis in cultured mouse podocytes. |
| Q35450699 | Upstream regulators and downstream effectors of NADPH oxidases as novel therapeutic targets for diabetic kidney disease |
| Q33613596 | Wild-type and mutant p53 differentially regulate NADPH oxidase 4 in TGF-β-mediated migration of human lung and breast epithelial cells |
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