NADPH-oxidase 4 protects against kidney fibrosis during chronic renal injury

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NADPH-oxidase 4 protects against kidney fibrosis during chronic renal injury is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1681/ASN.2012040373
P932PMC publication ID3507365
P698PubMed publication ID23100220

P50authorStellor Nlandu KhodoQ58642993
Ildiko SzantoQ64497565
P2093author name stringPierre-Yves Martin
Sophie de Seigneux
Eva Dizin
Eric Feraille
Karl Heinz Krause
Gaetan Sossauer
P2860cites workReactive oxygen species regulate angiogenesis and tumor growth through vascular endothelial growth factorQ40050607
NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation.Q40133141
Mineralocorticoid versus glucocorticoid receptor occupancy mediating aldosterone-stimulated sodium transport in a novel renal cell line.Q40451493
Antibodies against vascular endothelial growth factor improve early renal dysfunction in experimental diabetesQ43584934
Amelioration of long-term renal changes in obese type 2 diabetic mice by a neutralizing vascular endothelial growth factor antibodyQ44155579
Nox4 NAD(P)H oxidase mediates hypertrophy and fibronectin expression in the diabetic kidneyQ46681131
Peritubular capillary regression during the progression of experimental obstructive nephropathy.Q52546515
Structural-functional correlations in renal disease. II. The correlations.Q53005548
Number of interstitial capillary cross-sections assessed by monoclonal antibodies: relation to interstitial damageQ68381985
Protein kinase C-dependent phosphorylation of Na(+)-K(+)-ATPase alpha-subunit in rat kidney cortical tubulesQ71404365
Increased expression of TGF-beta 1 mRNA in the obstructed kidney of rats with unilateral ureteral ligationQ72934152
The definition, classification, and prognosis of chronic kidney disease: a KDIGO Controversies Conference reportQ82851228
Identification of renox, an NAD(P)H oxidase in kidneyQ22254385
Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transitionQ24301382
PDGF receptor-{beta} modulates metanephric mesenchyme chemotaxis induced by PDGF AAQ24316140
Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 geneQ24649776
The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiologyQ27860991
Subcellular localization of Nox4 and regulation in diabetesQ28566200
Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensingQ29617570
Proximal tubular injury and rapid formation of atubular glomeruli in mice with unilateral ureteral obstruction: a new look at an old modelQ30426142
Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathyQ30448126
Growth factors and apoptosis in neonatal ureteral obstructionQ30469396
NAD(P)H oxidase mediates TGF-beta1-induced activation of kidney myofibroblastsQ33562191
Activation of NRF2 by nitrosative agents and H2O2 involves KEAP1 disulfide formationQ33707203
Sirt1 activation protects the mouse renal medulla from oxidative injuryQ33755433
The NADPH oxidase subunit p22phox inhibits the function of the tumor suppressor protein tuberinQ33816437
NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis.Q34241578
Morphometric and visual evaluation of fibrosis in renal biopsiesQ34457313
Nox4 regulates Nrf2 and glutathione redox in cardiomyocytes in vivo.Q35038777
A key role for NOX4 in epithelial cell death during development of lung fibrosis.Q35185363
Reactive oxygen species derived from Nox4 mediate BMP2 gene transcription and osteoblast differentiation.Q35963391
Early loss of peritubular capillaries after kidney transplantation.Q36029152
Mechanisms of podocyte injury in diabetes: role of cytochrome P450 and NADPH oxidasesQ37163466
Oxidative stress in early diabetic nephropathy: fueling the fireQ37820092
P4510describes a project that usesImageJQ1659584
P433issue12
P304page(s)1967-1976
P577publication date2012-10-25
P1433published inJournal of the American Society of NephrologyQ17123893
P1476titleNADPH-oxidase 4 protects against kidney fibrosis during chronic renal injury
P478volume23

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cites work (P2860)
Q39120747Albuminuria induces a proinflammatory and profibrotic response in cortical collecting ducts via the 24p3 receptor
Q46558845Apocynin attenuates renal fibrosis via inhibition of NOXs-ROS-ERK-myofibroblast accumulation in UUO rats
Q46282840Both cardiomyocyte and endothelial cell Nox4 mediate protection against hemodynamic overload-induced remodeling
Q46155210Cardiac and renal upregulation of Nox2 and NF-κB and repression of Nox4 and Nrf2 in season- and diabetes-mediated models of vascular oxidative stress in guinea-pig and rat.
Q28533529Citral is renoprotective for focal segmental glomerulosclerosis by inhibiting oxidative stress and apoptosis and activating Nrf2 pathway in mice
Q38970003Coordinate activities of BRD4 and CDK9 in the transcriptional elongation complex are required for TGFβ-induced Nox4 expression and myofibroblast transdifferentiation.
Q38663704Crohn's Strictures-Moving Away from the Knife
Q48136402Cyclophilin D promotes tubular cell damage and the development of interstitial fibrosis in the obstructed kidney
Q37349206Diabetes and Kidney Disease: Role of Oxidative Stress
Q90343694Differential contribution of Nox1, Nox2 and Nox4 to kidney vascular oxidative stress and endothelial dysfunction in obesity
Q36125061GSTA3 Attenuates Renal Interstitial Fibrosis by Inhibiting TGF-Beta-Induced Tubular Epithelial-Mesenchymal Transition and Fibronectin Expression
Q33660629Genetic targeting or pharmacologic inhibition of NADPH oxidase nox4 provides renoprotection in long-term diabetic nephropathy
Q58797030Hydrogen peroxide derived from NADPH oxidase 4- and 2 contributes to the endothelium-dependent vasodilatation of intrarenal arteries
Q46419349Hydrogen sulfide inhibits high glucose-induced NADPH oxidase 4 expression and matrix increase by recruiting inducible nitric oxide synthase in kidney proximal tubular epithelial cells
Q46723438Intermedin is upregulated and attenuates renal fibrosis by inhibition of oxidative stress in rats with unilateral ureteral obstruction
Q36516977Matrix metalloproteinase 12 modulates high-fat-diet induced glomerular fibrogenesis and inflammation in a mouse model of obesity
Q35837331Myocardin-related Transcription Factor Regulates Nox4 Protein Expression: LINKING CYTOSKELETAL ORGANIZATION TO REDOX STATE.
Q37479906NADPH oxidase 4 deficiency increases tubular cell death during acute ischemic reperfusion injury.
Q37510779NADPH oxidase 4 deficiency reduces aquaporin-2 mRNA expression in cultured renal collecting duct principal cells via increased PDE3 and PDE4 activity
Q91989777NADPH oxidase 4 mediates TGF-β1/Smad signaling pathway induced acute kidney injury in hypoxia
Q37585797NADPH oxidase-mediated redox signaling promotes oxidative stress resistance and longevity through memo-1 in C. elegans
Q27027435NADPH oxidases in lung health and disease
Q37670311Nephropathy and elevated BP in mice with podocyte-specific NADPH oxidase 5 expression
Q37112788New Magnetic Resonance Imaging Index for Renal Fibrosis Assessment: A Comparison between Diffusion-Weighted Imaging and T1 Mapping with Histological Validation
Q38198872Novel targets of antifibrotic and anti-inflammatory treatment in CKD.
Q38335626Nox and renal disease.
Q36259413Nox2 is a mediator of ischemia reperfusion injury
Q38092960Nox4 and diabetic nephropathy: with a friend like this, who needs enemies?
Q47416018Nrf2 deficiency promotes the progression from acute tubular damage to chronic renal fibrosis following unilateral ureteral obstruction
Q52674866Oxidative Stress and Renal Fibrosis: Recent Insights for the Development of Novel Therapeutic Strategies.
Q92290748Oxidative Stress in the Pathogenesis and Evolution of Chronic Kidney Disease: Untangling Ariadne's Thread
Q31133726Plumbagin ameliorates diabetic nephropathy via interruption of pathways that include NOX4 signalling
Q55114983Possible Role of NADPH Oxidase 4 in Angiotensin II-Induced Muscle Wasting in Mice.
Q35880186Reactive Oxygen Species and Nuclear Factor Erythroid 2-Related Factor 2 Activation in Diabetic Nephropathy: A Hidden Target
Q27024762Reactive Oxygen-Related Diseases: Therapeutic Targets and Emerging Clinical Indications
Q26778527Redox Signaling in Diabetic Nephropathy: Hypertrophy versus Death Choices in Mesangial Cells and Podocytes
Q38188338Redox regulation of cardiac hypertrophy
Q37225203Redox signaling is an early event in the pathogenesis of renovascular hypertension
Q38938657Research review on the pharmacological effects of astragaloside IV.
Q35983620Reversal of persistent fibrosis in aging by targeting Nox4-Nrf2 redox imbalance
Q36764244Role of Nox2 in diabetic kidney disease
Q50062993TGF-β-mediated NADPH oxidase 4-dependent oxidative stress promotes colistin-induced acute kidney injury
Q36543727Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2α-mediated stress signaling
Q60961215The Use of Targeted Next Generation Sequencing to Explore Candidate Regulators of TGF-β1's Impact on Kidney Cells
Q34811358The angiotensin-converting enzyme 2/angiotensin (1-7)/Mas axis protects against lung fibroblast migration and lung fibrosis by inhibiting the NOX4-derived ROS-mediated RhoA/Rho kinase pathway
Q26786137The balance of powers: Redox regulation of fibrogenic pathways in kidney injury
Q34836065The role of reactive oxygen species in microvascular remodeling
Q38155196The signaling pathway of NADPH oxidase and its role in glomerular diseases
Q38858553Therapeutic potential of NADPH oxidase 1/4 inhibitors
Q92013418Transcription Factor 4 Regulates the Regeneration of Corneal Endothelial Cells
Q90699870Transient Receptor Potential Channel Canonical Type 3 Deficiency Antagonizes Myofibroblast Transdifferentiation In Vivo
Q93078156Tubular NOX4 expression decreases in chronic kidney disease but does not modify fibrosis evolution
Q38553671Tubular atrophy in the pathogenesis of chronic kidney disease progression
Q35587361p47(phox) contributes to albuminuria and kidney fibrosis in mice

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