Cellular and molecular mechanisms of fibrosis

scientific article

Cellular and molecular mechanisms of fibrosis is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1002/PATH.2277
P8608Fatcat IDrelease_ehg37mtqkbhwvenbsl2y37xmym
P3181OpenCitations bibliographic resource ID325300
P932PMC publication ID2693329
P698PubMed publication ID18161745
P5875ResearchGate publication ID5687235

P2093author name stringT A Wynn
P2860cites workInterleukin-10 and the interleukin-10 receptorQ24290912
Epithelial-mesenchymal transition and its implications for fibrosisQ24302042
The murine IL-13 receptor alpha 2: molecular cloning, characterization, and comparison with murine IL-13 receptor alpha 1Q24310131
Toll-like receptor signallingQ24570126
IL-13 receptor alpha 2 down-modulates granulomatous inflammation and prolongs host survival in schistosomiasisQ24597767
High-Throughput GoMiner, an 'industrial-strength' integrative gene ontology tool for interpretation of multiple-microarray experiments, with application to studies of Common Variable Immune Deficiency (CVID).Q24815153
The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosisQ28137622
IL-13 effector functionsQ28180348
Myofibroblasts and mechano-regulation of connective tissue remodellingQ28216468
Regulation of immune responses by TGF-betaQ28271433
IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosisQ28285105
Transforming growth factor-beta regulation of immune responsesQ28303115
RANTES and monocyte chemoattractant protein-1 (MCP-1) play an important role in the inflammatory phase of crescentic nephritis, but only MCP-1 is involved in crescent formation and interstitial fibrosisQ28307643
Eosinophils and T lymphocytes possess distinct roles in bleomycin-induced lung injury and fibrosisQ28510600
Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory responseQ28512142
Impaired host defense, hematopoiesis, granulomatous inflammation and type 1-type 2 cytokine balance in mice lacking CC chemokine receptor 1Q28591681
TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epitheliaQ29618875
Gelatinase A (MMP-2) is necessary and sufficient for renal tubular cell epithelial-mesenchymal transformationQ40646262
BMP7 antagonizes TGF-beta -dependent fibrogenesis in mesangial cellsQ40658343
Biology of the scleroderma fibroblastQ40835784
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin productionQ40849898
Introduction of the interleukin-10 gene into mice inhibited bleomycin-induced lung injury in vivoQ40883930
Anti-IL-4 treatment prevents dermal collagen deposition in the tight-skin mouse model of sclerodermaQ41005869
Lysyl oxidase-like protein localizes to sites of de novo fibrinogenesis in fibrosis and in the early stromal reaction of ductal breast carcinomas.Q41063030
Natural inhibitor of transforming growth factor-β protects against scarring in experimental kidney diseaseQ41078715
Plasmin regulates the activation of cell-associated latent TGF-beta 1 secreted by rat alveolar macrophages after in vivo bleomycin injuryQ41182225
Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1).Q42101278
Expression of interleukin-10 by in vitro and in vivo activated hepatic stellate cellsQ42448855
Protection from fluorescein isothiocyanate-induced fibrosis in IL-13-deficient, but not IL-4-deficient, mice results from impaired collagen synthesis by fibroblastsQ42458917
Impaired development of Th2 cells in IL-13-deficient mice.Q42462315
IL-13-induced chemokine responses in the lung: role of CCR2 in the pathogenesis of IL-13-induced inflammation and remodelingQ42518399
Blockade of transforming growth factor beta/Smad signaling in T cells by overexpression of Smad7 enhances antigen-induced airway inflammation and airway reactivityQ42944220
IL-21 receptor signaling is integral to the development of Th2 effector responses in vivoQ43459130
IL-12 attenuates bleomycin-induced pulmonary fibrosisQ43638697
Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in ratsQ43720079
Protection from pulmonary fibrosis in the absence of CCR2 signalingQ43760123
Disease fingerprinting with cDNA microarrays reveals distinct gene expression profiles in lethal type 1 and type 2 cytokine-mediated inflammatory reactions.Q43771291
Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: granulomatous pathology is shaped by the pattern of L-arginine metabolismQ43803694
Endogenous interleukin-10 modulates fibrosis and regeneration in experimental chronic pancreatitisQ43997200
IL-13 activates a mechanism of tissue fibrosis that is completely TGF-beta independentQ44007756
Alterations of beta-adrenergic signaling and cardiac hypertrophy in transgenic mice overexpressing TGF-beta(1).Q44103977
Interaction of IL-13 and C10 in the pathogenesis of bleomycin-induced pulmonary fibrosisQ44160763
In vitro production of B cell growth factor and B cell differentiation factor by peripheral blood mononuclear cells and bronchoalveolar lavage T lymphocytes from patients with idiopathic pulmonary fibrosisQ44536872
Multiple organ engraftment by bone-marrow-derived myofibroblasts and fibroblasts in bone-marrow-transplanted mice.Q44580904
Long-term interleukin 10 therapy in chronic hepatitis C patients has a proviral and anti-inflammatory effect.Q44598571
Role of interleukin-5 and eosinophils in allergen-induced airway remodeling in miceQ44771554
Schistosome infection of transgenic mice defines distinct and contrasting pathogenic roles for IL-4 and IL-13: IL-13 is a profibrotic agentQ44826352
Spontaneous recovery from micronodular cirrhosis: evidence for incomplete resolution associated with matrix cross-linkingQ44929886
A 7 gene signature identifies the risk of developing cirrhosis in patients with chronic hepatitis C.Q45965385
Interleukin 5 is required for the blood and tissue eosinophilia but not granuloma formation induced by infection with Schistosoma mansoniQ37656800
Subsets of murine lung fibroblasts express membrane-bound and soluble IL-4 receptors. Role of IL-4 in enhancing fibroblast proliferation and collagen synthesis.Q38309766
Receptors for interleukin-13 and interleukin-4 are complex and share a novel component that functions in signal transductionQ38317997
Loss or inhibition of uPA or MMP-9 attenuates LV remodeling and dysfunction after acute pressure overload in miceQ38584976
Periportal fibrosis in human Schistosoma mansoni infection is associated with low IL-10, low IFN-gamma, high TNF-alpha, or low RANTES, depending on age and genderQ38882456
Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13-induced inflammation and remodelingQ39735936
A chemokine receptor CCR-1 antagonist reduces renal fibrosis after unilateral ureter ligationQ39737420
Interleukin (IL) 4 and IL-13 act on human lung fibroblasts. Implication in asthma.Q39804205
Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitorsQ39807542
Human embryonic stem cell-derived cells rescue visual function in dystrophic RCS rats.Q40225932
A role for C-C chemokines in fibrotic lung diseaseQ40400981
Inhibition of airway remodeling in IL-5-deficient miceQ40553706
Mesenchymal stem cells as trophic mediatorsQ29619806
Endothelial-to-mesenchymal transition contributes to cardiac fibrosisQ29620566
The role of CXC chemokines in pulmonary fibrosisQ30443091
Macular degeneration: recent advances and therapeutic opportunities.Q33260025
Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repairQ33565774
Airway remodeling in asthmaQ33753444
Critical roles for IL-4, IL-5, and eosinophils in chronic skin allograft rejectionQ33852941
An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory responseQ33853821
Epithelial origin of myofibroblasts during fibrosis in the lungQ33996286
Lysyl oxidase-related protein-1 promotes tumor fibrosis and tumor progression in vivoQ34187677
Molecular mechanisms of antifibrotic effect of interferon gamma in bleomycin-mouse model of lung fibrosis: downregulation of TGF-beta and procollagen I and III gene expressionQ34371002
Angiotensin II and renal fibrosis.Q34376512
Matrix as a modulator of hepatic fibrogenesisQ34391368
CCR2-mediated recruitment of fibrocytes to the alveolar space after fibrotic injuryQ34399563
Non-Smad TGF-beta signalsQ34443708
Interleukin-5 (IL-5) augments the progression of liver fibrosis by regulating IL-13 activity.Q34491845
Transforming growth factor-beta in T-cell biologyQ34572232
The enemy within: keeping self-reactive T cells at bay in the peripheryQ34573771
The IL-21 receptor augments Th2 effector function and alternative macrophage activationQ34682153
Bone marrow-derived fibroblast precursors mediate ischemic cardiomyopathy in miceQ35141654
Smad3: a key player in pathogenetic mechanisms dependent on TGF-betaQ35157728
Bone marrow derivation of pericryptal myofibroblasts in the mouse and human small intestine and colonQ35594665
Viral hepatitis C.Q35617324
Mechanisms of pulmonary fibrosisQ35640281
Systemic sclerosis: a prototypic multisystem fibrotic disorderQ35649427
Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organQ35649446
Infectious disease, the innate immune response, and fibrosisQ35649461
Common and unique mechanisms regulate fibrosis in various fibroproliferative diseasesQ35649473
Fibrosis and diseases of the eye.Q35649477
Transcription factor T-bet regulates skin sclerosis through its function in innate immunity and via IL-13Q35669762
Mechanisms of tubulointerstitial fibrosisQ35741776
Stat6-deficient mice develop airway hyperresponsiveness and peribronchial fibrosis during chronic fungal asthma.Q35747373
Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiationQ35788867
Transforming Growth Factor-β-Dependent and -Independent Pathways of Induction of Tubulointerstitial Fibrosis in β6−/− MiceQ35792147
NOS-2 mediates the protective anti-inflammatory and antifibrotic effects of the Th1-inducing adjuvant, IL-12, in a Th2 model of granulomatous diseaseQ35829420
TGF-beta1 and angiotensin networking in cardiac remodelingQ35846911
Fibrotic disease and the T(H)1/T(H)2 paradigmQ35852270
Morbidity in schistosomiasis: an updateQ35881149
IL-13Ralpha2 and IL-10 coordinately suppress airway inflammation, airway-hyperreactivity, and fibrosis in miceQ35995705
Angiotensin II and the endothelium: diverse signals and effectsQ35998553
The eosinophil enigmaQ36057112
Pathogenesis of systemic sclerosis: altered B cell function is the key linking systemic autoimmunity and tissue fibrosis.Q36123039
Critical role for the chemokine MCP-1/CCR2 in the pathogenesis of bronchiolitis obliterans syndromeQ36168370
Chemokines provide the sustained inflammatory bridge between innate and acquired immunityQ36168977
Angiotensin and diabetic retinopathyQ36258479
Scleroderma: from cell and molecular mechanisms to disease modelsQ36259889
Mechanisms of disease: Mechanisms of hepatic fibrosis and therapeutic implicationsQ36304061
Intrinsic defect in T cell production of interleukin (IL)-13 in the absence of both IL-5 and eotaxin precludes the development of eosinophilia and airways hyperreactivity in experimental asthmaQ36369722
Enhanced interleukin (IL)-13 responses in mice lacking IL-13 receptor alpha 2.Q36370592
Regulation and function of the interleukin 13 receptor alpha 2 during a T helper cell type 2-dominant immune responseQ36370595
Transforming growth factor (TGF)-beta1-producing regulatory T cells induce Smad-mediated interleukin 10 secretion that facilitates coordinated immunoregulatory activity and amelioration of TGF-beta1-mediated fibrosisQ36371784
Immunostimulatory oligonucleotides block allergic airway inflammation by inhibiting Th2 cell activation and IgE-mediated cytokine inductionQ36403987
The role of circulating fibrocytes in fibrosisQ36434149
Circulating fibrocytes define a new leukocyte subpopulation that mediates tissue repairQ36437461
Matrix metalloproteases in aberrant fibrotic tissue remodelingQ36493982
NADPH oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosisQ36524368
Reversal of fibrosis: no longer a pipe dream?Q36680444
ECM remodeling in hypertensive heart diseaseQ36749281
Molecular mechanisms of hepatic fibrogenesisQ36849062
Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosisQ36849123
Local production of interleukin-4 during radiation-induced pneumonitis and pulmonary fibrosis in rats: macrophages as a prominent source of interleukin-4.Q36884168
Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstructionQ36991087
Global analysis of gene expression in pulmonary fibrosis reveals distinct programs regulating lung inflammation and fibrosisQ37117400
CD4(+) T helper cells engineered to produce latent TGF-beta1 reverse allergen-induced airway hyperreactivity and inflammationQ37303070
Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lungQ37370914
Hepatic fibrosis, glomerulosclerosis, and a lipodystrophy-like syndrome in PEPCK-TGF-beta1 transgenic miceQ37375446
Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: lymphocytic and eosinophilic inflammation without airway hyperreactivityQ37443188
Imatinib mesylate inhibits the profibrogenic activity of TGF-beta and prevents bleomycin-mediated lung fibrosisQ37591872
IL-13 is pivotal in the fibro-obliterative process of bronchiolitis obliterans syndromeQ46046480
SB 239063, a p38 MAPK inhibitor, reduces neutrophilia, inflammatory cytokines, MMP-9, and fibrosis in lungQ46903300
A significant proportion of myofibroblasts are of bone marrow origin in human liver fibrosisQ47839389
The interleukin-4/interleukin-13 receptor of human synovial fibroblasts: overexpression of the nonsignaling interleukin-13 receptor alpha2.Q48032045
Hematopoietic origins of fibroblasts: II. In vitro studies of fibroblasts, CFU-F, and fibrocytes.Q48662058
The C10/CCL6 chemokine and CCR1 play critical roles in the pathogenesis of IL-13-induced inflammation and remodeling.Q50232342
The role of IL-13 in established allergic airway disease.Q51696824
The bone marrow functionally contributes to liver fibrosis.Q51805517
Studies of murine schistosomiasis reveal interleukin-13 blockade as a treatment for established and progressive liver fibrosis.Q52543547
Antigen-specific production of interleukin (IL)-13 and IL-5 cooperate to mediate IL-4Ralpha-independent airway hyperreactivity.Q52957179
Increased bleomycin-induced skin fibrosis in mice lacking the Th1-specific transcription factor T-bet.Q53569849
TIMP-1 deficiency does not attenuate interstitial fibrosis in obstructive nephropathy.Q54276983
IL-10 regulates liver pathology in acute murine Schistosomiasis mansoni but is not required for immune down-modulation of chronic diseaseQ57339957
An IL-12-based vaccination method for preventing fibrosis induced by schistosome infectionQ59054213
Bone marrow endothelial progenitors are defective in systemic sclerosisQ62395162
The 72-kilodalton IE-1 protein of human cytomegalovirus (HCMV) is a potent inducer of connective tissue growth factor (CTGF) in human dermal fibroblastsQ64379370
Interleukin-4 stimulates collagen synthesis by normal and scleroderma fibroblasts in dermal equivalentsQ67881646
Production and function of murine macrophage inflammatory protein-1 alpha in bleomycin-induced lung injuryQ71656900
A type 2 (Th2-like) pattern of immune response predominates in the pulmonary interstitium of patients with cryptogenic fibrosing alveolitis (CFA)Q72034277
Anti-IL-4 treatment of Schistosoma mansoni-infected mice inhibits development of T cells and non-B, non-T cells expressing Th2 cytokines while decreasing egg-induced hepatic fibrosisQ72037712
A role for T helper 2 cells in mediating skin fibrosis in tight-skin miceQ72989109
Bleomycin-induced pulmonary fibrosis is independent of eosinophilsQ73092965
Lung interleukin-5 expression in murine bleomycin-induced pulmonary fibrosisQ73258653
Interferon-gamma inhibits experimental renal fibrosisQ73265447
Interleukin-10- and corticosteroid-induced reduction in type I procollagen in a human ex vivo scar cultureQ73372275
Pivotal role of CCR1-positive leukocytes in bleomycin-induced lung fibrosis in miceQ73458501
Interleukin-13 modulates collagen homeostasis in human skin and keloid fibroblastsQ73478890
Intestinal myofibroblasts in innate immune responses of the intestineQ73524252
Overexpression of transforming growth factor-beta1 and insulin-like growth factor-I in patients with idiopathic hypertrophic cardiomyopathyQ73606421
Therapeutic effect of IL-13 immunoneutralization during chronic experimental fungal asthmaQ73720946
IL-10 and the dangers of immune polarization: excessive type 1 and type 2 cytokine responses induce distinct forms of lethal immunopathology in murine schistosomiasisQ73869153
Airway remodeling is absent in CCR1-/- mice during chronic fungal allergic airway diseaseQ74027234
Proteome analysis of rat hepatic stellate cellsQ74071343
IL-5 deficiency abolishes aspects of airway remodelling in a murine model of lung inflammationQ74080040
Airway subepithelial fibrosis in a murine model of atopic asthma: suppression by dexamethasone or anti-interleukin-5 antibodyQ74089397
IL-13 induces airways hyperreactivity independently of the IL-4R alpha chain in the allergic lungQ74244301
Role of interleukin-13 in eosinophil accumulation and airway remodelling in a mouse model of chronic asthmaQ74417771
Regulation of hepatic fibrosis and extracellular matrix genes by the th response: new insight into the role of tissue inhibitors of matrix metalloproteinasesQ77337921
The role of IL-5 in bleomycin-induced pulmonary fibrosisQ77584421
Interleukin-10 expression and function in experimental murine liver inflammation and fibrosisQ77598613
Interleukin-10 controls neutrophilic infiltration, hepatocyte proliferation, and liver fibrosis induced by carbon tetrachloride in miceQ77598616
Global gene expression profiles during acute pathogen-induced pulmonary inflammation reveal divergent roles for Th1 and Th2 responses in tissue repairQ79074374
Association between enhanced type I collagen expression and epigenetic repression of the FLI1 gene in scleroderma fibroblastsQ79795007
Coexpression of IL-5 and eotaxin-2 in mice creates an eosinophil-dependent model of respiratory inflammation with characteristics of severe asthmaQ80427980
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)199-210
P577publication date2008-01-01
P1433published inJournal of PathologyQ400296
P1476titleCellular and molecular mechanisms of fibrosis
P478volume214

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cites work (P2860)
Q33784875"Hypoxia-induced down-regulation of microRNA-449a/b impairs control over targeted SERPINE1 (PAI-1) mRNA - a mechanism involved in SERPINE1 (PAI-1) overexpression".
Q42594342"Scar-cinoma": viewing the fibrotic lung mesenchymal cell in the context of cancer biology.
Q4810069111Beta-hydroxysteroid dehydrogenase-1 deficiency or inhibition enhances hepatic myofibroblast activation in murine liver fibrosis.
Q9299641815-Deoxy-∆-12,14-Prostaglandin J2 (15d-PGJ2), an Endogenous Ligand of PPAR-γ: Function and Mechanism
Q3659790617(R)-resolvin D1 ameliorates bleomycin-induced pulmonary fibrosis in mice
Q903933752-Methoxyestradiol attenuates liver fibrosis in mice: implications for M2 macrophages
Q928758645-Aryl-1,3,4-oxadiazol-2-ylthioalkanoic Acids: A Highly Potent New Class of Inhibitors of Rho/Myocardin-Related Transcription Factor (MRTF)/Serum Response Factor (SRF)-Mediated Gene Transcription as Potential Antifibrotic Agents for Scleroderma
Q355585335Z-7-Oxozeanol Inhibits the Effects of TGFβ1 on Human Gingival Fibroblasts
Q88418993A High-Throughput Assay for Collagen Secretion Suggests an Unanticipated Role for Hsp90 in Collagen Production
Q41789743A Hypothesis Concerning the Biphasic Dose-response of Tumors to Angiostatin and Endostatin
Q27333100A New Mouse Model That Spontaneously Develops Chronic Liver Inflammation and Fibrosis
Q36987505A Novel Nude Mouse Model of Hypertrophic Scarring Using Scratched Full Thickness Human Skin Grafts
Q36074303A Preliminary Study on Racial Differences in HMOX1, NFE2L2, and TGFβ1 Gene Polymorphisms and Radiation-Induced Late Normal Tissue Toxicity.
Q37402787A TGFbeta-responsive gene signature is associated with a subset of diffuse scleroderma with increased disease severity
Q36421134A TRPC6-dependent pathway for myofibroblast transdifferentiation and wound healing in vivo
Q41294425A Targeted Multiple Antigenic Peptide Vaccine Augments the Immune Response to Self TGF-β1 and Suppresses Ongoing Hepatic Fibrosis
Q46276542A Trickster in Disguise: Hyaluronan's Ambivalent Roles in the Matrix
Q36468611A case of biopsy-proven chronic kidney disease on progression from acute phosphate nephropathy
Q40642188A combination of liver fluke infection and traditional northeastern Thai foods associated with cholangiocarcinoma development
Q49964268A comparative study of different amniotic membrane orientations during extraocular muscle surgery in rabbits.
Q60932297A distinct epigenetic profile distinguishes stenotic from non-inflamed fibroblasts in the ileal mucosa of Crohn's disease patients
Q91895471A dose-ranging, parallel group, split-face, single-blind phase II study of light emitting diode-red light (LED-RL) for skin scarring prevention: study protocol for a randomized controlled trial
Q41642597A hepatic stellate cell gene expression signature associated with outcomes in hepatitis C cirrhosis and hepatocellular carcinoma after curative resection
Q35185363A key role for NOX4 in epithelial cell death during development of lung fibrosis.
Q42795715A large shRNA library approach identifies lncRNA Ntep as an essential regulator of cell proliferation
Q30155283A lipocalin-derived Peptide modulating fibroblasts and extracellular matrix proteins
Q33761119A longitudinal study of BCG vaccination in early childhood: the development of innate and adaptive immune responses
Q38393165A loss of telocytes accompanies fibrosis of multiple organs in systemic sclerosis
Q39697103A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy
Q47291343A novel personalized 3D injectable protein scaffold for regenerative medicine
Q34116805A novel, orally active LPA(1) receptor antagonist inhibits lung fibrosis in the mouse bleomycin model
Q55026656A phosphatidylinositol 3-kinase inhibitor strongly suppressed pulmonary vascular remodeling of allergic vasculitis in a murine model.
Q38929057A potent peptide as adiponectin receptor 1 agonist to against fibrosis
Q82770866A randomized prospective study of rehabilitation therapy in the treatment of radiation-induced dysphagia and trismus
Q37404262A review of the foreign-body response to subcutaneously-implanted devices: the role of macrophages and cytokines in biofouling and fibrosis
Q36905046A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response
Q34870775A2B adenosine receptor-mediated induction of IL-6 promotes CKD.
Q35138448ACE2 is augmented in dystrophic skeletal muscle and plays a role in decreasing associated fibrosis.
Q36375659ALS skeletal muscle shows enhanced TGF-β signaling, fibrosis and induction of fibro/adipogenic progenitor markers
Q50873709AMP-activated protein kinase/myocardin-related transcription factor-A signaling regulates fibroblast activation and renal fibrosis.
Q38698086AMPK in cardiac fibrosis and repair: Actions beyond metabolic regulation.
Q41822988Aberrant repair and fibrosis development in skeletal muscle
Q41520500Ablation of endothelial prolyl hydroxylase domain protein-2 promotes renal vascular remodelling and fibrosis in mice
Q39999843Absence of K-Ras Reduces Proliferation and Migration But Increases Extracellular Matrix Synthesis in Fibroblasts
Q33396838Accelerated and progressive and lethal liver fibrosis in mice that lack interleukin (IL)-10, IL-12p40, and IL-13Rα2.
Q38448103Accumulation of isolevuglandin-modified protein in normal and fibrotic lung
Q36488760Acellular normal and fibrotic human lung matrices as a culture system for in vitro investigation
Q42283646Acid sphingomyelinase deficiency contributes to resistance of scleroderma fibroblasts to Fas-mediated apoptosis
Q39010818Activated human hepatic stellate cells promote growth of human hepatocellular carcinoma in a subcutaneous xenograft nude mouse model
Q35767861Activated rat hepatic stellate cells influence Th1/Th2 profile in vitro
Q37240461Activation of MRTF-A-dependent gene expression with a small molecule promotes myofibroblast differentiation and wound healing
Q42638573Activation of STAT3 integrates common profibrotic pathways to promote fibroblast activation and tissue fibrosis
Q35863725Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis
Q37649641Activation of mTOR (mechanistic target of rapamycin) in rheumatic diseases
Q51859653Activation of the renin-angiotensin system in hyperoxia-induced lung fibrosis in neonatal rats.
Q64052496Activin a promotes myofibroblast differentiation of endometrial mesenchymal stem cells via STAT3-dependent Smad/CTGF pathway
Q36478984Adamts1 mediates ethanol-induced alterations in collagen and elastin via a FoxO1-sestrin3-AMPK signaling cascade in myocytes
Q33765783Adenosine A(2A) receptors promote collagen production by a Fli1- and CTGF-mediated mechanism.
Q36385392Adenosine A2A receptor plays an important role in radiation-induced dermal injury
Q50197688Adenosine A2a Receptor Blockade Diminishes Wnt/β-Catenin Signaling in a Murine Model of Bleomycin-Induced Dermal Fibrosis.
Q98158698Adipocytes protect fibroblasts from radiation-induced damage by adiponectin secretion
Q37202779Adiponectin promotes monocyte-to-fibroblast transition in renal fibrosis
Q36306603Adipose tissue fibrosis in human cancer cachexia: the role of TGFβ pathway
Q53187823Adipose tissue-derived stem cell treatment prevents renal disease progression.
Q37813497Adipose-derived stem cells for myocardial infarction
Q89976304Administration of Steamed and Freeze-Dried Mature Silkworm Larval Powder Prevents Hepatic Fibrosis and Hepatocellular Carcinogenesis by Blocking TGF-β/STAT3 Signaling Cascades in Rats
Q96953397Administration of Δ9-Tetrahydrocannabinol (THC) Post-Staphylococcal Enterotoxin B Exposure Protects Mice From Acute Respiratory Distress Syndrome and Toxicity
Q42719423Adrenomedullin in inflammatory process associated with experimental pulmonary fibrosis
Q36929585Advanced periductal fibrosis from infection with the carcinogenic human liver fluke Opisthorchis viverrini correlates with elevated levels of interleukin-6.
Q26799872Advances in Skin Substitutes-Potential of Tissue Engineered Skin for Facilitating Anti-Fibrotic Healing
Q99551284Advantage of fat-derived CD73 positive cells from multiple human tissues, prospective isolated mesenchymal stromal cells
Q46280910Adventitial Fibroblast Nox4 Expression and ROS Signaling in Pulmonary Arterial Hypertension
Q35235846Adverse host factors exacerbate occult HIV-associated nephropathy
Q38932043Adverse outcome pathway development from protein alkylation to liver fibrosis
Q42307037Adverse outcome pathways: opportunities, limitations and open questions
Q36063298Adverse renal and metabolic effects associated with oral sodium phosphate bowel preparation
Q57100000Aerosolized polymerized type I collagen reduces airway inflammation and remodelling in a guinea pig model of allergic asthma
Q45977362Age-related external anal sphincter muscle dysfunction and fibrosis: possible role of Wnt/β-catenin signaling pathways.
Q35155965Aging and Cardiac Fibrosis.
Q87851625Allograft inflammatory factor-1 alleviates liver disease of BALB/c mice infected with Schistosoma japonicum
Q45807860Allopurinol reverses liver damage induced by chronic carbon tetrachloride treatment by decreasing oxidative stress, TGF-β production and NF-κB nuclear translocation
Q42665165Alphav integrins lead the way for colorectal metastases
Q33686113Altered immunohistochemical expression of mast cell tryptase and chymase in the pathogenesis of oral submucous fibrosis and malignant transformation of the overlying epithelium
Q37972397Alternative origins of stroma in normal organs and disease
Q51193055Amelioration of high fat diet-induced nephropathy by cilostazol and rosuvastatin.
Q47235420Amnion Epithelial Cell-Derived Exosomes Restrict Lung Injury and Enhance Endogenous Lung Repair
Q34964361Amniotic fluid stem cells inhibit the progression of bleomycin-induced pulmonary fibrosis via CCL2 modulation in bronchoalveolar lavage
Q42396082Amphiregulin, an epidermal growth factor receptor ligand, plays an essential role in the pathogenesis of transforming growth factor-β-induced pulmonary fibrosis
Q35009520Amplified inhibition of stellate cell activation pathways by PPAR-γ, RAR and RXR agonists
Q33882346An alternative to lung inflammation and fibrosis
Q37294934Analysis of molecular mechanisms and anti-tumoural effects of zoledronic acid in breast cancer cells.
Q102152233Anatomical and histological analyses reveal that tail repair is coupled with regrowth in wild-caught, juvenile American alligators (Alligator mississippiensis)
Q39629598Andrographolide attenuates skeletal muscle dystrophy in mdx mice and increases efficiency of cell therapy by reducing fibrosis
Q40428093Angiopoietin-2/angiopoietin-1 as non-invasive biomarker of cirrhosis in chronic hepatitis C.
Q37490648Angiopoietin-like protein 2 induced by mechanical stress accelerates degeneration and hypertrophy of the ligamentum flavum in lumbar spinal canal stenosis
Q43015011Angiotensin II increases mRNA levels of all TGF-beta isoforms in quiescent and activated rat hepatic stellate cells.
Q30501039Angiotensin II overcomes strain-dependent resistance of rapid CKD progression in a new remnant kidney mouse model
Q28567529Angiotensin II promotes development of the renal microcirculation through AT1 receptors
Q34769458Angiotensin II type 1 receptor antagonist attenuates lacrimal gland, lung, and liver fibrosis in a murine model of chronic graft-versus-host disease
Q37626862Angiotensin Type-2 (AT-2)-Receptor activation reduces renal fibrosis in cyclosporine nephropathy: Evidence for blood-pressure independent effect
Q31053453Angiotensin-(1-7) suppresses the number and function of the circulating fibrocytes by upregulating endothelial nitric oxide synthase expression
Q33830299Angiotensin-II-induced apoptosis requires regulation of nucleolin and Bcl-xL by SHP-2 in primary lung endothelial cells
Q34086852Angiotensin-converting enzyme N-terminal inactivation alleviates bleomycin-induced lung injury
Q37122480Angiotensin-receptor blockers as therapy for mild-to-moderate hypertension-associated non-alcoholic steatohepatitis
Q38033380Animal models of intestinal fibrosis: new tools for the understanding of pathogenesis and therapy of human disease
Q40096184Another dimension to the importance of the extracellular matrix in fibrosis.
Q37706081Antagonism of Interleukin-17A ameliorates experimental hepatic fibrosis by restoring the IL-10/STAT3-suppressed autophagy in hepatocytes.
Q39427043Antagonistic regulation of transmembrane 4 L6 family member 5 attenuates fibrotic phenotypes in CCl(4) -treated mice
Q59803350Anti-Carcinogenic Glucosinolates in Cruciferous Vegetables and Their Antagonistic Effects on Prevention of Cancers
Q39453169Anti-TNFα alters the natural history of experimental Crohn's disease in rats when begun early, but not late, in disease
Q38850557Anti-fibrotic actions of relaxin.
Q35808540Anti-fibrotic effect of natural toxin bee venom on animal model of unilateral ureteral obstruction
Q38727002Anti-fibrotic effects of Salvia miltiorrhiza and Ligustrazine Injection on LX-2 cells involved with increased N-myc downstream-regulated gene 2 expression
Q41642089Anti-fibrotic effects of the Masson pine pollen aqueous extract on hepatic fibrosis rat model.
Q38895546Anti-fibrotic effects of valproic acid: role of HDAC inhibition and associated mechanisms
Q36837922Anti-melanin-concentrating hormone treatment attenuates chronic experimental colitis and fibrosis.
Q44132897Anti-tumor necrosis factor α prevents bowel fibrosis assessed by messenger RNA, histology, and magnetization transfer MRI in rats with Crohn's disease
Q33943907Antifibrotic effects of CXCL9 and its receptor CXCR3 in livers of mice and humans
Q39238770Antifibrotics in chronic liver disease: tractable targets and translational challenges
Q39182906Antiproliferative and cytotoxic effects of purple pitanga (Eugenia uniflora L.) extract on activated hepatic stellate cells.
Q24611248Aortic carboxypeptidase-like protein (ACLP) enhances lung myofibroblast differentiation through transforming growth factor β receptor-dependent and -independent pathways
Q54978248Aortic carboxypeptidase-like protein enhances adipose tissue stromal progenitor differentiation into myofibroblasts and is upregulated in fibrotic white adipose tissue.
Q37150761Aortic carboxypeptidase-like protein is expressed in fibrotic human lung and its absence protects against bleomycin-induced lung fibrosis.
Q36667057Apobec-1 Complementation Factor (A1CF) Inhibits Epithelial-Mesenchymal Transition and Migration of Normal Rat Kidney Proximal Tubular Epithelial Cells
Q90290725Apoptosis Resistance in Fibroblasts Precedes Progressive Scarring in Pulmonary Fibrosis and Is Partially Mediated by Toll-Like Receptor 4 Activation
Q53069927Apoptosis induction of cardiomyocytes and subsequent fibrosis after irradiation and neoadjuvant chemotherapy.
Q64094470Application of Manual Therapy for Dysphagia in Head and Neck Cancer Patients: A Preliminary National Survey of Treatment Trends and Adverse Events
Q37848921Architecture and the extracellular matrix: the still unappreciated components of the adipose tissue
Q39386624Arp2/3 is critical for lamellipodia and response to extracellular matrix cues but is dispensable for chemotaxis
Q50128617Arteriovenous fistula stenosis in hemodialysis patients is characterized by an increased adventitial fibrosis.
Q28387702Asbestos-associated mesothelial cell autoantibodies promote collagen deposition in vitro
Q37317161Asiatic acid isolated from Centella asiatica inhibits TGF-β1-induced collagen expression in human keloid fibroblasts via PPAR-γ activation
Q38873704Asiaticoside hinders the invasive growth of keloid fibroblasts through inhibition of the GDF-9/MAPK/Smad pathway
Q30444857Assessment of clinical signs of liver cirrhosis using T1 mapping on Gd-EOB-DTPA-enhanced 3T MRI
Q53382047Assessment of liver fibrosis by variable flip angle T1 mapping at 3.0T.
Q33637776Association between depressive symptoms and fibrosis markers: the Cardiovascular Health Study
Q28070358Astaxanthin as a Potential Protector of Liver Function: A Review
Q34112121Asthmatic airway epithelial cells differentially regulate fibroblast expression of extracellular matrix components.
Q55000649Astragaloside Inhibits Hepatic Fibrosis by Modulation of TGF-β1/Smad Signaling Pathway.
Q57268472Atrophy, Fibrosis, and Increased PAX7-Positive Cells in Pharyngeal Muscles of Oculopharyngeal Muscular Dystrophy Patients
Q38023852Autoantibodies and resident renal cells in the pathogenesis of lupus nephritis: getting to know the unknown.
Q39319936Autophagy and mesenchymal cell fibrogenesis
Q35274466Autophagy is a regulator of TGF-β1-induced fibrogenesis in primary human atrial myofibroblasts
Q36227227Autophagy releases lipid that promotes fibrogenesis by activated hepatic stellate cells in mice and in human tissues.
Q42875432Azithromycin reduces pulmonary fibrosis in a bleomycin mouse model
Q24658641B-cell depletion attenuates serological biomarkers of fibrosis and myofibroblast activation in IgG4-related disease
Q36105254BARD1 mediates TGF-β signaling in pulmonary fibrosis.
Q47432301BDNF-ERK1/2 signaling pathway in ketamine-associated lower urinary tract symptoms
Q57046535BML-111 suppresses TGF-β1-induced lung fibroblast activation in vitro and decreases experimental pulmonary fibrosis in vivo
Q50583140BMP-2 induces a profibrotic phenotype in adult renal progenitor cells through Nox4 activation.
Q42709318BMP-6 emerges as a potential major regulator of fibrosis in the kidney
Q43613927BMP-7 attenuates TGF-β1-induced fibroblast-like differentiation of rat dermal papilla cells
Q90651745BRD4 inhibitor JQ1 inhibits and reverses mechanical injury-induced corneal scarring
Q36419888BRD4 is a novel therapeutic target for liver fibrosis
Q37696175Babao Dan attenuates hepatic fibrosis by inhibiting hepatic stellate cells activation and proliferation via TLR4 signaling pathway.
Q28383273Bacterial lipopolysaccharide enhances PDGF signaling and pulmonary fibrosis in rats exposed to carbon nanotubes
Q54250942Baicalein attenuates hypertrophic scar formation via inhibition of the transforming growth factor-β/Smad2/3 signalling pathway.
Q38967954Basic Signaling in Cardiac Fibroblasts
Q53159771Basophils Trigger Fibroblast Activation in Cardiac Allograft Fibrosis Development.
Q45170033Betel-derived alkaloid up-regulates keratinocyte alphavbeta6 integrin expression and promotes oral submucous fibrosis.
Q93364846Biomarkers Associated with Lymphedema and Fibrosis in Patients with Cancer of the Head and Neck
Q35208530Biomaterials that regulate growth factor activity via bioinspired interactions
Q38237390Biomechanics of TGFβ-induced epithelial-mesenchymal transition: implications for fibrosis and cancer
Q33730117Bleomycin and IL-1beta-mediated pulmonary fibrosis is IL-17A dependent
Q47776900Blockade of Bradykinin receptors worsens the dystrophic phenotype of mdx mice: differential effects for B1 and B2 receptors
Q34263666Blockade of osteopontin inhibits glomerular fibrosis in a model of anti-glomerular basement membrane glomerulonephritis.
Q34358339Blockade of transforming growth factor-beta1 accelerates lymphatic regeneration during wound repair
Q41643283Blocking HMGB1 signal pathway protects early radiation-induced lung injury.
Q35064880Blocking follistatin-like 1 attenuates bleomycin-induced pulmonary fibrosis in mice
Q91690142Blocking interleukin-6 trans-signaling protects against renal fibrosis by suppressing STAT3 activation
Q33360714Blocking of angiotensin II is more than blocking of transforming growth factor-beta
Q33943997Blocking sirtuin 1 and 2 inhibits renal interstitial fibroblast activation and attenuates renal interstitial fibrosis in obstructive nephropathy
Q29048610Blocking the 4-1BB Pathway Ameliorates Crystalline Silica-induced Lung Inflammation and Fibrosis in Mice
Q34559028Blocking the class I histone deacetylase ameliorates renal fibrosis and inhibits renal fibroblast activation via modulating TGF-beta and EGFR signaling
Q39402781Bone morphogenetic protein-7 inhibits proximal tubular epithelial cell Smad3 signaling via increased SnoN expression.
Q37617540Bone regeneration: the stem/progenitor cells point of view
Q50087003Brg1 promotes liver fibrosis via activation of hepatic stellate cells.
Q90492059CARdiac Immunotherapy: T Cells Engineered to Treat the Fibrotic Heart
Q38861910CB1 cannabinoid receptor antagonist attenuates left ventricular hypertrophy and Akt-mediated cardiac fibrosis in experimental uremia
Q35740902CB2R orchestrates fibrogenesis through regulation of inflammatory response during the repair of skeletal muscle contusion
Q92377646CCAAT/enhancer binding protein delta (C/EBPδ) deficiency does not affect bleomycin-induced pulmonary fibrosis
Q55024109CCL20 is up-regulated in non-alcoholic fatty liver disease fibrosis and is produced by hepatic stellate cells in response to fatty acid loading.
Q34027926CCN1/CYR61: the very model of a modern matricellular protein.
Q53404791CCN2 and CCN5 exerts opposing effect on fibroblast proliferation and transdifferentiation induced by TGF-β.
Q36703006CD11b+ and Sca-1+ Cells Exert the Main Beneficial Effects of Systemically Administered Bone Marrow-Derived Mononuclear Cells in a Murine Model of Mixed Th2/Th17 Allergic Airway Inflammation
Q52844028CD31+ Cells From Peripheral Blood Facilitate Bone Regeneration in Biologically Impaired Conditions Through Combined Effects on Immunomodulation and Angiogenesis.
Q34490750CD4(+) cells regulate fibrosis and lymphangiogenesis in response to lymphatic fluid stasis
Q37394389CD4+ T cells control the differentiation of Gr1+ monocytes into fibrocytes
Q84618859CD4+ T cells: a potential player in renal fibrosis
Q45715929CD44v3-v10 reduces the profibrotic effects of TGF-β1 and attenuates tubular injury in the early stage of chronic obstructive nephropathy
Q39493006CTGF/CCN-2 over-expression can directly induce features of skeletal muscle dystrophy
Q43159403CXC chemokine ligand 4 (Cxcl4) is a platelet-derived mediator of experimental liver fibrosis
Q34485215CXC-type chemokines promote myofibroblast phenoconversion and prostatic fibrosis
Q50309115CXCL12/CXCR4-Mediated Procollagen Secretion Is Coupled To Cullin-RING Ubiquitin Ligase Activation.
Q58779664CXCL6-EGFR-induced Kupffer cells secrete TGF-β1 promoting hepatic stellate cell activation via the SMAD2/BRD4/C-MYC/EZH2 pathway in liver fibrosis
Q35790264Cadherin-11 contributes to pulmonary fibrosis: potential role in TGF-β production and epithelial to mesenchymal transition
Q41840520Caffeic Acid Phenethyl Ester inhibit Hepatic Fibrosis by Nitric Oxide Synthase and Cystathionine Gamma-Lyase in Rats
Q92752898Can Nrf2 Modulate the Development of Intestinal Fibrosis and Cancer in Inflammatory Bowel Disease?
Q42334109Can a fibrotic liver afford epithelial-mesenchymal transition?
Q57170745Can host reaction animal models be used to predict and modulate skin regeneration?
Q86151439Canine visceral leishmaniasis as a systemic fibrotic disease
Q42178812Cardiac Lymphatic Vessels, Transport, and Healing of the Infarcted Heart.
Q35174316Cardiac MR imaging to probe tissue composition of the heart by using T1 mapping
Q38103213Cardiac and respiratory dysfunction in Duchenne muscular dystrophy and the role of second messengers.
Q34162142Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-β.
Q37253735Cardiac repair and regeneration: the Rubik's cube of cell therapy for heart disease
Q51695893Cartilage oligomeric matrix protein participates in the pathogenesis of liver fibrosis.
Q52659952Cartilage oligomeric matrix protein: COMPopathies and beyond.
Q46816517Caspase-3 activation and increased procollagen type I in irradiated hearts.
Q41347086Casticin attenuates liver fibrosis and hepatic stellate cell activation by blocking TGF-β/Smad signaling pathway
Q34256372Cathepsin S deficiency results in abnormal accumulation of autophagosomes in macrophages and enhances Ang II-induced cardiac inflammation
Q41382922Cell plasticity in wound healing: paracrine factors of M1/ M2 polarized macrophages influence the phenotypical state of dermal fibroblasts
Q36220879Cell signals influencing hepatic fibrosis
Q38259227Cellular and Molecular Mediators of Intestinal Fibrosis
Q42252132Cellular and molecular mechanisms of intestinal fibrosis
Q35903772Cellular and molecular mechanisms of renal fibrosis
Q96126917Cellular census of human fibrosis defines functionally distinct stromal cell types and states
Q37093579Cellular mechanisms of tissue fibrosis. 4. Structural and functional consequences of skeletal muscle fibrosis
Q33840143Cellular mechanisms of tissue fibrosis. 8. Current and future drug targets in fibrosis: focus on Rho GTPase-regulated gene transcription.
Q50484272Cellular or Exosomal microRNAs Associated with CCN Gene Expression in Liver Fibrosis.
Q24602488Cellular senescence controls fibrosis in wound healing
Q37848468Cellular/extracellular matrix cross-talk in scar evolution and control.
Q92048945Characterization of IL-19, -20, and -24 in acute and chronic kidney diseases reveals a pro-fibrotic role of IL-24
Q47839477Characterization of dermal myofibroblast differentiation in pseudoxanthoma elasticum.
Q49570420Characterization of pulmonary responses in mice to asbestos/asbestiform fibers using gene expression profiles.
Q37434655Characterization of the inflammatory and fibrotic response in a mouse model of cardiac pressure overload.
Q58758969Chemokine-Induced Macrophage Polarization in Inflammatory Conditions
Q37502208Chemokines and cardiac fibrosis.
Q26778684Chemokines in Wound Healing and as Potential Therapeutic Targets for Reducing Cutaneous Scarring
Q34056271Chemokines in the immunopathogenesis of hepatitis C infection
Q28484977Chitinase 3-like 1 protein levels are elevated in Schistosoma haematobium infected children
Q84797678Chronic alcohol consumption induces cardiac remodeling in mice from Th1 or Th2 background
Q38027046Chronic inflammation and lung fibrosis: pleotropic syndromes but limited distinct phenotypes
Q34448187Chronic nerve growth factor exposure increases apoptosis in a model of in vitro induced conjunctival myofibroblasts
Q35102810Cinnabar induces renal inflammation and fibrogenesis in rats
Q49344588Circuit Design Features of a Stable Two-Cell System.
Q64244673Circular RNAs in immune responses and immune diseases
Q34785428Circulating microRNAs as a Fingerprint for Liver Cirrhosis
Q35675409Clarithromycin Attenuates Radiation-Induced Lung Injury in Mice
Q37477801Clinical Benefits of Biochemical Markers of Fibrosis in Egyptian Children With Chronic Liver Diseases.
Q30583901Clinical and biochemical profiles suggest fibromuscular dysplasia is a systemic disease with altered TGF-β expression and connective tissue features
Q91741461Clinical significance of the immune cell landscape in hepatocellular carcinoma patients with different degrees of fibrosis
Q51428417Clinical strategies for the alleviation of contractures from a predictive mathematical model of dermal repair.
Q86867451Co-localization of LTBP-2 with FGF-2 in fibrotic human keloid and hypertrophic scar
Q38950679Coculture with intraocular lens material-activated macrophages induces an inflammatory phenotype in lens epithelial cells
Q89551749ColXV Aggravates Adipocyte Apoptosis by Facilitating Abnormal Extracellular Matrix Remodeling in Mice
Q64091690Collagen Fibrils Mechanically Contribute to Tissue Contraction in an In Vitro Wound Healing Scenario
Q33840471Collagen I matrix turnover is regulated by fibronectin polymerization
Q34959537Combined effect of pro- and anti-inflammatory cytokine gene polymorphisms on susceptibility to liver cirrhosis in Tunisian HCV-infected patients.
Q52366287Comparative regenerative mechanisms across different mammalian tissues.
Q36630982Comparison of acute proton, photon, and low-dose priming effects on genes associated with extracellular matrix and adhesion molecules in the lungs
Q40374177Comparison of collagen content in skin wounds evaluated by biochemical assay and by computer-aided histomorphometric analysis
Q41632625Comprehensive phenotyping of regulatory T cells after liver transplantation.
Q37777427Congenital ureteropelvic junction obstruction: human disease and animal models
Q44783314Connective tissue cells expressing fibro/adipogenic progenitor markers increase under chronic damage: relevance in fibroblast-myofibroblast differentiation and skeletal muscle fibrosis
Q36903759Connective tissue growth factor causes EMT-like cell fate changes in vivo and in vitro.
Q33637142Connexins, Pannexins, and Their Channels in Fibroproliferative Diseases
Q53763050Contractile function recovery in severely injured gastrocnemius muscle of rats treated with either oleic or linoleic acid.
Q36353622Contribution and Mobilization of Mesenchymal Stem Cells in a mouse model of carbon tetrachloride-induced liver fibrosis.
Q58799997Contribution of STAT3 to Inflammatory and Fibrotic Diseases and Prospects for its Targeting for Treatment
Q38879377Contribution of collagen adhesion receptors to tissue fibrosis
Q34905520Contribution of intestinal smooth muscle to Crohn's disease fibrogenesis
Q38046545Contribution of myeloid cell subsets to liver fibrosis in parasite infection
Q36007887Corneal myofibroblast biology and pathobiology: generation, persistence, and transparency
Q53180514Correlation between circulating fibrocytes, and activity and progression of interstitial lung diseases.
Q64068193Critical Role of Cysteine-Rich Protein 61 in Mediating the Activation of Renal Fibroblasts
Q36420270Cross regulation between hypoxia-inducible transcription factor-1α (HIF-1α) and transforming growth factor (TGF)-ß1 mediates nickel oxide nanoparticles (NiONPs)-induced pulmonary fibrosis
Q38204265Crosstalk between fibroblasts and inflammatory cells
Q47415780Cryopreserved rabbit amniotic membrane alleviated inflammatory response and fibrosis following experimental strabismus surgery in rabbits
Q46682082Curative diet supplementation with a melon superoxide dismutase reduces adipose tissue in obese hamsters by improving insulin sensitivity
Q37624991Curcumin Suppresses Intestinal Fibrosis by Inhibition of PPARγ-Mediated Epithelial-Mesenchymal Transition
Q46654417Curcumin prevents cisplatin-induced decrease in the tight and adherens junctions: relation to oxidative stress
Q37603804Current concepts in clinical radiation oncology
Q49507866Current perspectives on the role of CD8+ T cells in systemic sclerosis.
Q35228505Curtailing endothelial TGF-β signaling is sufficient to reduce endothelial-mesenchymal transition and fibrosis in CKD
Q39481263Cysteine-rich protein 1 is regulated by transforming growth factor-β1 and expressed in lung fibrosis.
Q37899786Cytoglobin: biochemical, functional and clinical perspective of the newest member of the globin family
Q37209512Cytokine mediated tissue fibrosis
Q50082480Cytokines in tendon disease: A Systematic Review.
Q38543692Cytokines in the immunopathology of systemic sclerosis
Q53105395Cytologic features of hepatic fibrosis in dogs: a retrospective study on 22 cases.
Q35886245Cytosolic phospholipase A₂: physiological function and role in disease
Q93210153DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome
Q33722844Dabigatran, a direct thrombin inhibitor, demonstrates antifibrotic effects on lung fibroblasts.
Q54231908Dasatinib attenuated bleomycin-induced pulmonary fibrosis in mice.
Q92750611Dasatinib plus quercetin prevents uterine age-related dysfunction and fibrosis in mice
Q28607792Dating Endometriotic Ovarian Cysts Based on the Content of Cyst Fluid and its Potential Clinical Implications
Q36158847Deciphering mechanisms of staphylococcal biofilm evasion of host immunity
Q57716457Deciphering the disease-related molecular networks using urine proteomics
Q37044614Deconstructing the mechanisms and consequences of TGF-β-induced EMT during cancer progression
Q35085132Decorin interacts with connective tissue growth factor (CTGF)/CCN2 by LRR12 inhibiting its biological activity
Q92354819Deficient Skeletal Muscle Regeneration after Injury Induced by a Clostridium perfringens Strain Associated with Gas Gangrene
Q34217585Degradation of internalized αvβ5 integrin is controlled by uPAR bound uPA: effect on β1 integrin activity and α-SMA stress fiber assembly
Q35188138Delayed administration of suramin attenuates the progression of renal fibrosis in obstructive nephropathy
Q42156139Deletion of a tumor necrosis superfamily gene in mice leads to impaired healing that mimics chronic wounds in humans.
Q37057161Delta-Like Ligand 4 Modulates Liver Damage by Down-Regulating Chemokine Expression
Q42095796Delta-like 1 serves as a new target and contributor to liver fibrosis down-regulated by mesenchymal stem cell transplantation
Q53206104Depletion of Hepatic Macrophages Aggravates Liver Lesions Induced in Rats by Thioacetamide (TAA).
Q39402319Design, synthesis and anti-fibrosis activity study of N₁-substituted phenylhydroquinolinone derivatives.
Q45392095Detection of Epstein-Barr virus-encoded small RNA-expressed myofibroblasts and IgG4-producing plasma cells in sclerosing angiomatoid nodular transformation of the spleen
Q44206690Development of Fibrosis in Acute and Longstanding Ulcerative Colitis
Q98196787Development of a miniaturized 96-Transwell air-liquid interface human small airway epithelial model
Q51502123Development of an In Vitro Assay to Evaluate Contractile Function of Mesenchymal Cells that Underwent Epithelial-Mesenchymal Transition.
Q36296876Diabetes-induced renal injury in rats is attenuated by suramin
Q36589609Diabetic nephropathy: the role of inflammation in fibroblast activation and kidney fibrosis
Q33820556Differences in irradiated lung gene transcription between fibrosis-prone C57BL/6NHsd and fibrosis-resistant C3H/HeNHsd mice
Q36414956Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis
Q38568865Differential effects of Smad3 targeting in a murine model of chronic kidney disease
Q48300010Differential expression and localization of human tissue inhibitors of metalloproteinases in proliferative diabetic retinopathy
Q40173528Differential expression of microRNA and predicted targets in pulmonary sarcoidosis
Q47135902Dioscin Exerts Protective Effects Against Crystalline Silica-induced Pulmonary Fibrosis in Mice
Q64264709Dipeptidyl peptidase-4 plays a pathogenic role in BSA-induced kidney injury in diabetic mice
Q28387716Direct isolation of myofibroblasts and fibroblasts from bleomycin-injured lungs reveals their functional similarities and differences
Q36040154Discovery and validation of a molecular signature for the noninvasive diagnosis of human renal allograft fibrosis
Q86531984Disease modification in systemic sclerosis. Do integrated approaches offer new challenges?
Q48341303Disruption of the Hedgehog signaling pathway in inflammatory bowel disease fosters chronic intestinal inflammation
Q37129967Distinct roles for mammalian target of rapamycin complexes in the fibroblast response to transforming growth factor-beta
Q43791563Distinct spatio-temporal extracellular matrix accumulation within demyelinated spinal cord lesions in Theiler's murine encephalomyelitis
Q26825368Diverse functions of matrix metalloproteinases during fibrosis
Q35581445Diverse inflammatory responses in transgenic mouse models of Alzheimer's disease and the effect of immunotherapy on these responses
Q36923555Diversity of lipid mediators in human adipose tissue depots.
Q41551456Doxazosin Treatment Attenuates Carbon Tetrachloride-Induced Liver Fibrosis in Hamsters through a Decrease in Transforming Growth Factor β Secretion
Q47119118Drugs and Targets in Fibrosis
Q91846149Dual TBK1/IKKɛ inhibitor amlexanox attenuates the severity of hepatotoxin-induced liver fibrosis and biliary fibrosis in mice
Q41894002Dual targeting of MEK and PI3K pathways attenuates established and progressive pulmonary fibrosis.
Q26775091Dynamic role of myofibroblasts in oral lesions
Q29619873Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis
Q49428049Dystrophic Cardiomyopathy: Complex Pathobiological Processes to Generate Clinical Phenotype.
Q92494590ERK Pathway in Activated, Myofibroblast-Like, Hepatic Stellate Cells: A Critical Signaling Crossroad Sustaining Liver Fibrosis
Q39879394ERK and PI3K regulate different aspects of the epithelial to mesenchymal transition of mammary tumor cells induced by truncated MUC1.
Q91933381ERK1/2 drives IL-1β-induced expression of TGF-β1 and BMP-2 in torn tendons
Q38930830EW-7197 inhibits hepatic, renal, and pulmonary fibrosis by blocking TGF-β/Smad and ROS signaling
Q60641610Early Systemic Sclerosis: Serum Profiling of Factors Involved in Endothelial, T-cell, and Fibroblast Interplay is Marked by Elevated Interleukin-33 Levels
Q37216048Early infiltration of p40IL12(+)CCR7(+)CD11b(+) cells is critical for fibrosis development
Q50070886Early intervention by Captopril does not improve wound healing of partial thickness burn wounds in a rat model.
Q36655405Early loss of pericytes and perivascular stromal cell-induced scar formation after stroke
Q34231374Effect of RhoA on transforming growth factor β1-induced rat hepatic stellate cell migration
Q43021349Effect of an immunotoxin to folate receptor beta on bleomycin-induced experimental pulmonary fibrosis
Q46590750Effect of cryopreserved amniotic membrane on the development of adhesions and fibrosis after extraocular muscle surgery in rabbits
Q34526130Effect of interleukin 6 deficiency on renal interstitial fibrosis
Q54365521Effect of nilotinib on bleomycin-induced acute lung injury and pulmonary fibrosis in mice.
Q49580788Effect of photobiomodulation on connective tissue remodeling and regeneration of skeletal muscle in elderly rats.
Q89606643Effect of sarcolipin-mediated cell transdifferentiation in sarcopenia-associated skeletal muscle fibrosis
Q37227633Effectiveness of rosiglitazone in reducing flexion contracture in a rabbit model of arthrofibrosis with surgical capsular release: A biomechanical, histological, and genetic analysis
Q27027082Effector mechanisms of rejection
Q92526479Effects of PARP-1 Deficiency and Histamine H4 Receptor Inhibition in an Inflammatory Model of Lung Fibrosis in Mice
Q33686400Effects of nanoporous alumina on inflammatory cell response
Q54394597Effects of silencing transforming growth factor-β1 by RNA interference plasmid on rat renal allograft fibrosis using Smads pathway.
Q44119643Effects of vitamin C on cytotherapy-mediated muscle regeneration
Q34533385Effects on contralateral muscles after unilateral electrical muscle stimulation and exercise
Q28482283Efficacy of a novel class of RNA interference therapeutic agents
Q37754720Eicosanoids in inflammation and cancer: the role of COX-2.
Q38779316Electrostatic and Hydrophobic Interactions Mediate Single-Stranded DNA Recognition and Acta2 Repression by Purine-Rich Element-Binding Protein B.
Q54237984Elevated Levels of Urinary 8-oxodG Correlate with Persistent Periductal Fibrosis after Praziquantel Treatment in Chronic Opisthorchiasis.
Q34784648Elevated serum beta-glucuronidase reflects hepatic lysosomal fragility following toxic liver injury in rats.
Q36063833Emerging PPARγ-Independent Role of PPARγ Ligands in Lung Diseases
Q92106745Emerging Roles for Eph Receptors and Ephrin Ligands in Immunity
Q38603674Enalapril treatment discloses an early role of angiotensin II in inflammation- and oxidative stress-related muscle damage in dystrophic mdx mice
Q38990632Endostar, a novel human recombinant endostatin, attenuates liver fibrosis in CCl4-induced mice
Q54122943Endostatin Stimulates Proliferation and Migration of Myofibroblasts Isolated from Myocardial Infarction Model Rats.
Q47118793Endostatin inhibits fibrosis by modulating the PDGFR/ERK signal pathway: an in vitro study.
Q54982965Endothelial to Mesenchymal Transition Represents a Key Link in the Interaction between Inflammation and Endothelial Dysfunction.
Q37278453Endothelial to mesenchymal transition via transforming growth factor-beta1/Smad activation is associated with portal venous stenosis in idiopathic portal hypertension.
Q36173804Endothelial-mesenchymal transition and its contribution to the emergence of stem cell phenotype
Q38555492Endothelial-to-mesenchymal transition contributes to the myofibroblast population in proliferative diabetic retinopathy
Q90522780Endothelin Receptor Antagonists: Status Quo and Future Perspectives for Targeted Therapy
Q35141755Endotoxin induces fibrosis in vascular endothelial cells through a mechanism dependent on transient receptor protein melastatin 7 activity.
Q38754809Engineering approaches to study fibrosis in 3-D in vitro systems.
Q37026406Enhanced protection from fibrosis and inflammation in the combined absence of IL-13 and IFN-γ
Q37052016Enhancer of Zeste Homolog 2 Inhibition Attenuates Renal Fibrosis by Maintaining Smad7 and Phosphatase and Tensin Homolog Expression
Q26829416Environmental attributes to respiratory diseases of small ruminants
Q28543011Environmental particulate (PM2.5) augments stiffness-induced alveolar epithelial cell mechanoactivation of transforming growth factor beta
Q91720874Eosinophils and Macrophages within the Th2-Induced Granuloma: Balancing Killing and Healing in a Tight Space
Q43257498Eosinophils infiltrate thyroids, but have no apparent role in induction or resolution of experimental autoimmune thyroiditis in interferon-gamma(-/-) mice
Q34735424Eosinophils promote epithelial to mesenchymal transition of bronchial epithelial cells.
Q38858284Epigenetic Therapy for the Treatment of Hypertension-Induced Cardiac Hypertrophy and Fibrosis.
Q38985933Epigenetic regulation of hepatic stellate cell activation and liver fibrosis
Q36113039Epigenetics and the overhealing wound: the role of DNA methylation in fibrosis
Q38218535Epigenetics in radiation-induced fibrosis
Q38034837Epigenetics within the matrix: a neo-regulator of fibrotic disease
Q90246026Epithelial Cell Cycle Behaviour in the Injured Kidney
Q37591248Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury
Q37762478Epithelial mesenchymal transition traits in human breast cancer cell lines parallel the CD44(hi/)CD24 (lo/-) stem cell phenotype in human breast cancer
Q35107649Epithelial regulation of mesenchymal tissue behavior
Q39242491Epithelial to Mesenchymal Transition (EMT) and Endothelial to Mesenchymal Transition (EndMT): Role and Implications in Kidney Fibrosis
Q33947224Epithelial to mesenchymal transition in gingival overgrowth
Q59800302Epithelial-mesenchymal transition in keloid tissue
Q53482048Epithelial-mesenchymal transition in keloid tissues and TGF-β1-induced hair follicle outer root sheath keratinocytes.
Q36104434Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis
Q37456459Epithelial-to-mesenchymal transitions in the liver
Q30656354Esophageal epithelial cells acquire functional characteristics of activated myofibroblasts after undergoing an epithelial to mesenchymal transition
Q57821348Established and novel pathophysiological mechanisms of pericardial injury and constrictive pericarditis
Q53759519Evaluation of Antivascular Combretastatin A4 P Efficacy Using Supersonic Shear Imaging Technique of Ectopic Colon Carcinoma CT26.
Q37648477Evaluation of TGF-β1 and MCP-1 expression and tubulointerstitial fibrosis in children with Henoch-Schönlein purpura nephritis and IgA nephropathy: A clinical correlation
Q34575461Evaluation of capsular and acapsular strains of S. aureus in an experimental brain abscess model
Q55155378Evaluation of liver fibrosis with a monoexponential model of intravoxel incoherent motion magnetic resonance imaging.
Q49207421Evaluation of myofibroblasts in oral submucous fibrosis and oral squamous cell carcinoma: The pathogenesis and correlation.
Q64901830Evaluation of the Diagnostic Potential of uPAR as a Biomarker in Renal Biopsies of Patients with FSGS.
Q93335290Evaluation of the antifibrotic potency by knocking down SPARC, CCR2 and SMAD3
Q90416829Evaluation of transforming growth factor beta 1 in dogs with osteoarthritis
Q90218556Evaluation via Supervised Machine Learning of the Broiler Pectoralis Major and Liver Transcriptome in Association With the Muscle Myopathy Wooden Breast
Q35903075Evidence of a Role for Fibroblast Transient Receptor Potential Canonical 3 Ca2+ Channel in Renal Fibrosis
Q47763199Evodiamine ameliorates liver fibrosis in rats via TGF-β1/Smad signaling pathway
Q38006732Evolving role of molecular imaging for new understanding: targeting myofibroblasts to predict remodeling
Q91649266Evolving therapies for Peyronie's disease: how can we work towards new drugs?
Q64235554Exercise promotes a cardioprotective gene program in resident cardiac fibroblasts
Q35204841Exogenous administration of thiosulfate, a donor of hydrogen sulfide, attenuates angiotensin II-induced hypertensive heart disease in rats
Q49918232Expression of CTGF/CCN2 in response to LPA is stimulated by fibrotic extracellular matrix via the integrin/FAK axis.
Q94595628Expression of Collagen (Types I, III, and V), HSP47, MMP-2, and TIMP-1 in Retrobulbar Adipose Tissue of Patients with Thyroid-Associated Orbitopathy
Q54548435Expression of autotaxin and acylglycerol kinase in proliferative vitreoretinal epiretinal membranes.
Q42619210Expression of high-mobility groups box-1/receptor for advanced glycation end products/osteopontin/early growth response-1 pathway in proliferative vitreoretinal epiretinal membranes.
Q41846598Expression of nestin, vimentin, and NCAM by renal interstitial cells after ischemic tubular injury
Q28472170Expression-based network biology identifies alteration in key regulatory pathways of type 2 diabetes and associated risk/complications
Q50513904Extracellular matrix alterations and acute inflammation; developing in parallel during early induction of pulmonary fibrosis.
Q58725635Extracellular matrix collagen I promotes the tumor progression of residual hepatocellular carcinoma after heat treatment
Q92092671Extracellular matrix composition of connective tissues: a systematic review and meta-analysis
Q33694487Extracellular matrix molecules: potential targets in pharmacotherapy.
Q36672445Extracellular matrix remodeling: the common denominator in connective tissue diseases. Possibilities for evaluation and current understanding of the matrix as more than a passive architecture, but a key player in tissue failure
Q37776560Extracellular matrix roles during cardiac repair.
Q91869856FGF-2 inhibits contractile properties of valvular interstitial cell myofibroblasts encapsulated in 3D MMP-degradable hydrogels
Q45869235FOXA2 alleviates CCl4-induced liver fibrosis by protecting hepatocytes in mice
Q42577317Fabrication of biocompatible, vibrational magnetoelastic materials for controlling cellular adhesion
Q49721777Falcarindiol inhibits LPS-induced inflammation via attenuating MAPK and JAK-STAT signaling pathways in murine macrophage RAW 264.7 cells.
Q98226258Fate of Adipose Progenitor Cells in Obesity-Related Chronic Inflammation
Q24627446Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression
Q89822068FibroAtlas: A Database for the Exploration of Fibrotic Diseases and Their Genes
Q64296038Fibroadhesive scarring of grafted collagen scaffolds interferes with implant-host neural tissue integration and bridging in experimental spinal cord injury
Q38047232Fibroblast autophagy in fibrotic disorders
Q41090863Fibroblast paracrine TNF-α signaling elevates integrin A5 expression in idiopathic pulmonary fibrosis (IPF).
Q83190809Fibroblast progenitor cells are recruited into the myocardium prior to the development of myocardial fibrosis
Q41151245Fibroblast-Extracellular Matrix Interactions in Tissue Fibrosis
Q38737904Fibroblast-Specific Genetic Manipulation of p38 Mitogen-Activated Protein Kinase In Vivo Reveals Its Central Regulatory Role in Fibrosis
Q47094281Fibroblast-specific TGF-β-Smad2/3 signaling underlies cardiac fibrosis
Q33916995Fibroblast-specific expression of AC6 enhances beta-adrenergic and prostacyclin signaling and blunts bleomycin-induced pulmonary fibrosis.
Q39589852Fibroblast/fibrocyte: surface interaction dictates tissue reactions to micropillar implants
Q37836316Fibroblasts and myofibroblasts: what are we talking about?
Q28390280Fibrocytes Regulate Wilms Tumor 1-Positive Cell Accumulation in Severe Fibrotic Lung Disease
Q89831197Fibrocytes, Wound Healing, and Corneal Fibrosis
Q30432829Fibrocytes: bringing new insights into mechanisms of inflammation and fibrosis
Q38542592Fibrogenesis, novel lessons from animal models
Q36515027Fibronectin regulates Wnt7a signaling and satellite cell expansion
Q37983629Fibroproliferative disorders and their mechanobiology
Q64954227Fibroproliferative genes are preferentially expressed in central centrifugal cicatricial alopecia.
Q35584016Fibrosing mediastinitis complicating prior histoplasmosis is associated with human leukocyte antigen DQB1*04:02 - a case control study
Q26801150Fibrosis Related Inflammatory Mediators: Role of the IL-10 Cytokine Family
Q91511304Fibrosis and secondary lymphedema: chicken or egg?
Q47376188Fibrosis imaging: Current concepts and future directions
Q40556586Fibrosis is not just fibrosis - basement membrane modelling and collagen metabolism differs between hepatitis B- and C-induced injury
Q35825861Fibrosis is regulated by Th2 and Th17 responses and by dynamic interactions between fibroblasts and macrophages
Q42908292Fibrosis under arrest
Q33865082Fibrosis-dependent mechanisms of hepatocarcinogenesis
Q34076151Fibrosis-related biomarkers and incident cardiovascular disease in older adults: the cardiovascular health study
Q37834449Fibrotic response of tissue remodeling in COPD.
Q38947654Flightless I is a key regulator of the fibroproliferative process in hypertrophic scarring and a target for a novel antiscarring therapy
Q47942170Fluorescence of Picrosirius Red Multiplexed With Immunohistochemistry for the Quantitative Assessment of Collagen in Tissue Sections.
Q54571621Fluorofenidone attenuates tubulointerstitial fibrosis by inhibiting TGF-β(1)-induced fibroblast activation.
Q53066784Focal adhesion kinase (FAK) siRNA inhibits human hypertrophic scar by suppressing integrin α, TGF-β and α-SMA.
Q35688439Focal adhesion kinase links mechanical force to skin fibrosis via inflammatory signaling.
Q33518024Focus on collagen: in vitro systems to study fibrogenesis and antifibrosis state of the art.
Q36310562Follistatin attenuates radiation-induced fibrosis in a murine model
Q35035034Follistatin is induced by ionizing radiation and potentially predictive of radiosensitivity in radiation-induced fibrosis patient derived fibroblasts
Q37411925Fractalkine and TGF-beta1 levels reflect the severity of chronic pancreatitis in humans
Q36040200Fresolimumab treatment decreases biomarkers and improves clinical symptoms in systemic sclerosis patients
Q34935524From fish to amphibians to mammals: in search of novel strategies to optimize cardiac regeneration
Q38839005Frontal fibrosing alopecia: reflections and hypotheses on aetiology and pathogenesis
Q89564286Fructose-1,6-Bisphosphate Prevents Bleomycin-Induced Pulmonary Fibrosis in Mice and Inhibits the Proliferation of Lung Fibroblasts
Q33886281Functional genomics unique to week 20 post wounding in the deep cone/fat dome of the Duroc/Yorkshire porcine model of fibroproliferative scarring.
Q37107125Functions of autophagy in normal and diseased liver
Q53566281GGPPS deficiency aggravates CCl4-induced liver injury by inducing hepatocyte apoptosis.
Q64949910Gal-3 Deficiency Suppresses Novosphyngobium aromaticivorans Inflammasome Activation and IL-17 Driven Autoimmune Cholangitis in Mice.
Q48159180Galectin-3: One Molecule for an Alphabet of Diseases, from A to Z.
Q37396937Gammadelta T cells and Th17 cytokines in hypersensitivity pneumonitis and lung fibrosis
Q26829291Gammaherpesviruses and pulmonary fibrosis: evidence from humans, horses, and rodents
Q24634120Garcinia Cambogia attenuates diet-induced adiposity but exacerbates hepatic collagen accumulation and inflammation
Q90722857Gas6/TAM System: A Key Modulator of the Interplay between Inflammation and Fibrosis
Q82577081Gender-related distribution of the interleukin-1 beta and interleukin-1 receptor antagonist gene polymorphisms in patients with end-stage liver disease
Q37047953Gene delivery of TGF-β1 induces arthrofibrosis and chondrometaplasia of synovium in vivo
Q34516594Gene expression analysis of the pleiotropic effects of TGF-β1 in an in vitro model of flexor tendon healing
Q41779182Gene expression profiling of connective tissue growth factor (CTGF) stimulated primary human tenon fibroblasts reveals an inflammatory and wound healing response in vitro.
Q38507233Gene set analysis of lung samples provides insight into pathogenesis of progressive, fibrotic pulmonary sarcoidosis.
Q37207519Genes regulated by caloric restriction have unique roles within transcriptional networks
Q38210815Genetic determinants of pulmonary fibrosis: evolving concepts
Q36722534Genetic differences in oxidative stress and inflammatory responses to diet-induced obesity do not alter liver fibrosis in mice
Q35110974Genetic factors regulating lung vasculature and immune cell functions associate with resistance to pneumococcal infection
Q30429015Genetic inactivation of IL-1 signaling enhances atherosclerotic plaque instability and reduces outward vessel remodeling in advanced atherosclerosis in mice
Q35917468Genetic or pharmacologic blockade of EGFR inhibits renal fibrosis.
Q90451156Genetic or pharmacologic blockade of enhancer of zeste homolog 2 inhibits the progression of peritoneal fibrosis
Q36373332Genetic testing in diffuse parenchymal lung disease
Q33912109Genome-wide RNA-Sequencing analysis identifies a distinct fibrosis gene signature in the conjunctiva after glaucoma surgery
Q39875402Genomic phenotype of non-cultured pulmonary fibroblasts in idiopathic pulmonary fibrosis
Q58800112Ghrelin Ameliorates Angiotensin II-Induced Myocardial Fibrosis by Upregulating Peroxisome Proliferator-Activated Receptor Gamma in Young Male Rats
Q94560412Ginsenosides: potential therapeutic source for fibrosis-associated human diseases
Q55966751Glibenclamide protects against thioacetamide-induced hepatic damage in Wistar rat: investigation on NLRP3, MMP-2, and stellate cell activation
Q28533371Global gene expression profiling in PAI-1 knockout murine heart and kidney: molecular basis of cardiac-selective fibrosis
Q35707164Glucagon-Like Peptide 1 Protects against Hyperglycemic-Induced Endothelial-to-Mesenchymal Transition and Improves Myocardial Dysfunction by Suppressing Poly(ADP-Ribose) Polymerase 1 Activity
Q40244126Glycyrrhizic acid inhibits apoptosis and fibrosis in carbon-tetrachloride-induced rat liver injury
Q36999185Gradually softening hydrogels for modeling hepatic stellate cell behavior during fibrosis regression
Q34408266Graft versus host disease in the bone marrow, liver and thymus humanized mouse model
Q64043403Growth rate and myofibroblast differentiation of desmoid fibroblast-like cells are modulated by TGF-β signaling
Q35914655Gualou Xiebai decoction inhibits cardiac dysfunction and inflammation in cardiac fibrosis rats
Q64084368HDAC Inhibitors: Therapeutic Potential in Fibrosis-Associated Human Diseases
Q36588493HDAC inhibitors in experimental liver and kidney fibrosis
Q47835828HIF1A up-regulates the ADORA2B receptor on alternatively activated macrophages and contributes to pulmonary fibrosis
Q50045865HIV and Cardiovascular Disease: Role of Immunometabolic Perturbations.
Q36991838Halofuginone suppresses growth of human uterine leiomyoma cells in a mouse xenograft model
Q38046124Hanging in the balance: endogenous anti-inflammatory mechanisms in tissue repair and fibrosis
Q40858204Healing the scars of life-targeting redox imbalance in fibrotic disorders of the elderly
Q35918416Heat Shock Protein 27 Plays a Pivotal Role in Myofibroblast Differentiation and in the Development of Bleomycin-Induced Pulmonary Fibrosis.
Q34978646Hematopoietic progenitor cell mobilization is mediated through beta-2 and beta-3 receptors after injury
Q38010172Heme oxygenase, inflammation, and fibrosis: the good, the bad, and the ugly?
Q98771721Hepatic Stellate Cells and Hepatocarcinogenesis
Q36167581Hepatic expression of serum amyloid A1 is induced by traumatic brain injury and modulated by telmisartan
Q41707214Hepatic fibrogenesis and transforming growth factor/Smad signaling activation in rats chronically exposed to low doses of lead
Q50061923Hepatic fibropoiesis in dogs naturally infected with Leishmania (Leishmania) infantum treated with liposome-encapsulated meglumine antimoniate and allopurinol.
Q36699261Hepatic regeneration and the epithelial to mesenchymal transition
Q34361002Hepatocyte growth factor inhibits apoptosis by the profibrotic factor angiotensin II via extracellular signal-regulated kinase 1/2 in endothelial cells and tissue explants
Q41360012Hepatocyte-specific ablation of PP2A catalytic subunit α attenuates liver fibrosis progression via TGF-β1/Smad signaling.
Q43045645Hepatotrophic factors reduce hepatic fibrosis in rats
Q36502066Hepcidin in non-alcoholic fatty liver disease regulated by the TLR4/NF-κB signaling pathway
Q34690834Herbal compound "Songyou Yin" attenuates hepatoma cell invasiveness and metastasis through downregulation of cytokines secreted by activated hepatic stellate cells
Q42041903High doses of TGF-β potently suppress type I collagen via the transcription factor CUX1.
Q33916249High throughput determination of TGFβ1/SMAD3 targets in A549 lung epithelial cells
Q47402576High-throughput approaches for screening and analysis of cell behaviors
Q35632155Histone acetyltransferase inhibitor C646 reverses epithelial to mesenchymal transition of human peritoneal mesothelial cells via blocking TGF-β1/Smad3 signaling pathway in vitro
Q28571005Histone deacetylase 1/2 mediates proliferation of renal interstitial fibroblasts and expression of cell cycle proteins
Q41774831Histone methyltransferase ASH1 orchestrates fibrogenic gene transcription during myofibroblast transdifferentiation
Q36907090Histone modifications are responsible for decreased Fas expression and apoptosis resistance in fibrotic lung fibroblasts.
Q48297020Histopathological characteristics of interstitial cystitis/bladder pain syndrome without Hunner lesion.
Q26852800Host responses in tissue repair and fibrosis
Q37842633How has research into cytokine interactions and their role in driving immune responses impacted our understanding of periodontitis?
Q52536468Human Fibrotic Diseases: Current Challenges in Fibrosis Research.
Q45501605Human alternatives to fetal bovine serum for the expansion of mesenchymal stromal cells from bone marrow.
Q42465609Human lung parenchyma but not proximal bronchi produces fibroblasts with enhanced TGF-beta signaling and alpha-SMA expression.
Q41762985Human relaxin gene expression delivered by bioreducible dendrimer polymer for post-infarct cardiac remodeling in rats
Q28544929Hyaluronidase modulates inflammatory response and accelerates the cutaneous wound healing
Q92246784Hydrogel-based delivery of Il-10 improves treatment of bleomycin-induced lung fibrosis in mice
Q27011111Hydrogen Sulfide as a Potential Therapeutic Target in Fibrosis
Q35640718Hydrogen Sulfide: A Therapeutic Candidate for Fibrotic Disease?
Q28383532Hypoxia-Induced Epithelial-Mesenchymal Transition Is Involved in Bleomycin-Induced Lung Fibrosis
Q37420926Hypoxia-induced collagen synthesis of human lung fibroblasts by activating the angiotensin system
Q35022857Hypoxia-inducible factor-1α contributes to the profibrotic action of angiotensin II in renal medullary interstitial cells
Q38038330ICRP publication 118: ICRP statement on tissue reactions and early and late effects of radiation in normal tissues and organs--threshold doses for tissue reactions in a radiation protection context
Q89542063IL-11 in cardiac and renal fibrosis: Late to the party but a central player
Q46257233IL-11 is a crucial determinant of cardiovascular fibrosis.
Q38010706IL-13 Signaling in Liver Fibrogenesis
Q36102435IL-13 induces skin fibrosis in atopic dermatitis by thymic stromal lymphopoietin.
Q37396941IL-17A-expressing T cells are essential for bacterial clearance in a murine model of hypersensitivity pneumonitis
Q37474764IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis.
Q38990683ISSLS PRIZE IN BASIC SCIENCE 2017: Intervertebral disc/bone marrow cross-talk with Modic changes
Q37424190Iatrogenic inflammatory fibrosis of hard palate in a 13-year-old female patient
Q35942655Identification and characterization of an anti-fibrotic benzopyran compound isolated from mangrove-derived Streptomyces xiamenensis
Q99371195Identification of differentially expressed long non-coding RNAs and mRNAs in orbital adipose/connective tissue of thyroid-associated ophthalmopathy
Q34089734Identification of protein marker in vaginal wall tissues of women with stress urinary incontinence by protein chip array
Q59136293Identification of the Toxicity Pathways Associated With Thioacetamide-Induced Injuries in Rat Liver and Kidney
Q37304042Identification of two novel anti-fibrotic benzopyran compounds produced by engineered strains derived from Streptomyces xiamenensis M1-94P that originated from deep-sea sediments
Q41856522Identifying common genes and networks in multi-organ fibrosis
Q60956228Identifying the Growth Factors for Improving Neointestinal Regeneration in Rats through Transcriptome Analysis Using RNA-Seq Data
Q27015533Immune Components of Liver Damage Associated with Connective Tissue Diseases
Q55519564Immune Regulation of Skin Wound Healing: Mechanisms and Novel Therapeutic Targets.
Q91666106Immune heterogeneity of head and tail pancreatic lymph nodes in non-obese diabetic mice
Q58795413Immune mechanisms in the different phases of acute tubular necrosis
Q30471805Immune-inflammatory dysregulation modulates the incidence of progressive fibrosis and diastolic stiffness in the aging heart
Q42730468Immunohistochemical characterization of macrophages and myofibroblasts in α-Naphthylisothiocyanate (ANIT)--induced bile duct injury and subsequent fibrogenesis in rats
Q37802002Immunological aspect of cardiac remodeling: T lymphocyte subsets in inflammation-mediated cardiac fibrosis
Q46412441Immunological detection of the type V collagen propeptide fragment, PVCP-1230, in connective tissue remodeling associated with liver fibrosis
Q38018539Immunological orchestration of liver fibrosis
Q52658037Immunology Guides Skeletal Muscle Regeneration.
Q90612947Immunomodulation for maxillofacial reconstructive surgery
Q64935041Immunomodulation of liver injury by Ascaris suum extract in an experimental model of autoimmune hepatitis.
Q38407555Immunopathogenesis of Myocarditis: The Interplay Between Cardiac Fibroblast Cells, Dendritic Cells, Macrophages and CD4+ T Cells
Q38262108Immunopathogenesis of chronic hepatitis B.
Q36070624Immunophenotypic alterations in resident immune cells and myocardial fibrosis in the aging rhesus macaque (Macaca mulatta) heart
Q27339979Impaired skeletal muscle regeneration in the absence of fibrosis during hibernation in 13-lined ground squirrels
Q37403094In liver fibrosis, dendritic cells govern hepatic inflammation in mice via TNF-alpha
Q39003492In vitro methods of assessing ocular biocompatibility using THP-1-derived macrophages
Q30313657In vitro study of the host responses to model biomaterials via a fibroblast/macrophage co-culture system.
Q35131446In vivo metabolism study of xiamenmycin A in mouse plasma by UPLC-QTOF-MS and LC-MS/MS.
Q37325619Increase in cellular cyclic AMP concentrations reverses the profibrogenic phenotype of cardiac myofibroblasts: a novel therapeutic approach for cardiac fibrosis
Q33390722Increased Expression of Connective Tissue Growth Factor (CTGF) in Multiple Organs After Exposure of Non-Human Primates (NHP) to Lethal Doses of Radiation
Q35587144Increased Expression of TGF-β Signaling Components in a Mouse Model of Fibrosis Induced by Submandibular Gland Duct Ligation
Q36446246Increased peri-ductal collagen micro-organization may contribute to raised mammographic density.
Q45348104Increased plasma tissue inhibitors of metalloproteinase concentrations as negative predictors associated with deterioration of kidney allograft function upon long-term observation
Q41625139Indoleamine 2, 3-dioxygenase (IDO) increases during renal fibrogenesis and its inhibition potentiates TGF-β 1-induced epithelial to mesenchymal transition.
Q36015400Induction of MiR-21 by Stereotactic Body Radiotherapy Contributes to the Pulmonary Fibrotic Response.
Q36414300Induction of alternatively activated macrophages enhances pathogenesis during severe acute respiratory syndrome coronavirus infection
Q83358567Induction of elastin expression in vascular endothelial cells relates to hepatoportal sclerosis in idiopathic portal hypertension: possible link to serum anti-endothelial cell antibodies
Q46103260Induction of phenotype modifying cytokines by FERMT1 mutations.
Q92691246Infiltrating CCR2+ monocytes and their progenies, fibrocytes, contribute to colon fibrosis by inhibiting collagen degradation through the production of TIMP-1
Q38047815Inflammasomes in wound healing and fibrosis
Q38107461Inflammation and liver tumorigenesis
Q47305480Inflammation and renal fibrosis: Recent developments on key signaling molecules as potential therapeutic targets.
Q36352894Inflammatory Gene Expression Upon TGF-β1-Induced p38 Activation in Primary Dupuytren's Disease Fibroblasts.
Q37631642Inflammatory Manifestations of Lymphedema
Q34857355Inflammatory leukocyte phenotypes correlate with disease progression in idiopathic pulmonary fibrosis.
Q43877721Inflammatory response of intervertebral disc cells is reduced by fibrin sealant scaffold in vitro
Q53580573Influence of Renal Sympathetic Denervation on Cardiac Extracellular Matrix Turnover and Cardiac Fibrosis.
Q33785553Influence of sex and disease severity on gene expression profiles in individuals with idiopathic pulmonary fibrosis
Q29615715Inhaled multiwalled carbon nanotubes potentiate airway fibrosis in murine allergic asthma
Q39668344Inhibition of ATIR by shRNA prevents collagen synthesis in hepatic stellate cells
Q38829813Inhibition of H3K9 histone methyltransferase G9a attenuates renal fibrosis and retains klotho expression
Q38740549Inhibition of connective tissue growth factor attenuates paraquat-induced lung fibrosis in a human MRC-5 cell line
Q43269848Inhibition of extracellular signal-regulated kinase 1 by adenovirus mediated small interfering RNA attenuates hepatic fibrosis in rats
Q37417291Inhibition of histone deacetylase activity attenuates renal fibroblast activation and interstitial fibrosis in obstructive nephropathy.
Q35387975Inhibition of mechanical stress-induced hypertrophic scar inflammation by emodin
Q35236478Inhibition of myocardin-related transcription factor/serum response factor signaling decreases lung fibrosis and promotes mesenchymal cell apoptosis.
Q37314369Inhibition of platelet activation by clopidogrel prevents hypertension-induced cardiac inflammation and fibrosis
Q51302199Inhibition of radiation-induced skin fibrosis with imatinib.
Q46501803Inhibitory Effects of Astragaloside IV on Bleomycin-Induced Pulmonary Fibrosis in Rats Via Attenuation of Oxidative Stress and Inflammation
Q35137520Inhibitory role of the KEAP1-NRF2 pathway in TGFβ1-stimulated renal epithelial transition to fibroblastic cells: a modulatory effect on SMAD signaling.
Q38855505Injectable nanofibrous spongy microspheres for NR4A1 plasmid DNA transfection to reverse fibrotic degeneration and support disc regeneration.
Q53402699Innate Lymphoid Cells: A Promising New Regulator in Fibrotic Diseases.
Q35665474Innate immune responses and modified extracellular matrix regulation characterize bacterial infection and cellular/connective tissue changes in scarring trachoma.
Q39488300Insulin-like growth factor binding protein 5 enhances survival of LX2 human hepatic stellate cells
Q77790315Integration of inflammation, fibrosis, and cancer induced by carbon nanotubes
Q42110868Integrative Systems Biology Investigation of Fabry Disease.
Q47139621Integrin alpha 11 in the regulation of the myofibroblast phenotype: implications for fibrotic diseases.
Q97421999Integrin alpha-5 silencing leads to myofibroblastic differentiation in IPF-derived human lung fibroblasts
Q38219401Integrins and cadherins as therapeutic targets in fibrosis
Q90666328Interaction between sphingosine kinase/sphingosine 1 phosphate and transforming growth factor-β/Smads pathways in experimental intestinal fibrosis. An in vivo immunohistochemical study
Q47109594Interactions between TGF-β1, canonical WNT/β-catenin pathway and PPAR γ in radiation-induced fibrosis
Q38675553Interferon-γ Treatment of Human Laryngotracheal Stenosis-Derived Fibroblasts
Q35197060Interferon-λ rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease.
Q39855944Interleukin-1 beta regulates proximal tubular cell transforming growth factor beta-1 signalling
Q39609153Interleukin-13 is involved in the formation of liver fibrosis in Clonorchis sinensis-infected mice
Q36379539Interleukin-13 protects from atherosclerosis and modulates plaque composition by skewing the macrophage phenotype
Q38753216Interleukin-33 in tumorigenesis, tumor immune evasion, and cancer immunotherapy
Q37572817Interleukin-6 signaling drives fibrosis in unresolved inflammation
Q37433780Intestinal fibrosis in IBD--a dynamic, multifactorial process
Q48174194Intestinal fibrosis is associated with lack of response to Infliximab therapy in Crohn's disease
Q64893939Intratunical Injection of Human Adipose Tissue-Derived Stem Cells Restores Collagen III/I Ratio in a Rat Model of Chronic Peyronie's Disease.
Q93112241Intratunical injection of autologous adipose stromal vascular fraction reduces collagen III expression in a rat model of chronic penile fibrosis
Q33559677Investigating the role of P311 in the hypertrophic scar
Q38992978Involvement of Nrf2-GSH signaling in TGFβ1-stimulated epithelial-to-mesenchymal transition changes in rat renal tubular cells
Q37820315Involvement of bone-marrow-derived cells in kidney fibrosis
Q99588205Is there a role for oxidative stress and mitochondrial dysfunction in age-associated bladder disorders?
Q38756929Is there any role of epithelial to mesenchymal transition in the pathogenesis of contrast nephropathy?
Q36101161Isoform-Specific Modulation of Inflammation Induced by Adenoviral Mediated Delivery of Platelet-Derived Growth Factors in the Adult Mouse Heart
Q88947003Isoform-specific effects of transforming growth factor β on endothelial-to-mesenchymal transition
Q39945162IκB kinase-beta inhibitor attenuates hepatic fibrosis in mice
Q44062259JNK1/2 siRNA inhibits transforming-growth factor-beta1-induced connective tissue growth factor expression and fibrotic function in THSFs
Q33756048KLF4 Plays an Essential Role in Corneal Epithelial Homeostasis by Promoting Epithelial Cell Fate and Suppressing Epithelial-Mesenchymal Transition
Q64269669Ketamine‑induced bladder dysfunction is associated with extracellular matrix accumulation and impairment of calcium signaling in a mouse model
Q38282776Klotho and renal fibrosis
Q57718617La fibrose tubulo-interstitielle rénale
Q54309806Lack of the serum- and glucocorticoid-inducible kinase SGK1 improves muscle force characteristics and attenuates fibrosis in dystrophic mdx mouse muscle.
Q41894225Laser capture microdissection and multiplex-tandem PCR analysis of proximal tubular epithelial cell signaling in human kidney disease.
Q48337942Late urinary morbidity and quality of life after radical prostatectomy and salvage radiotherapy for prostate cancer
Q49613258LepR+ cells dispute hegemony with Gli1+ cells in bone marrow fibrosis.
Q34299086Leptin promotes the myofibroblastic phenotype in hepatic stellate cells by activating the hedgehog pathway.
Q40757564Leukemia inhibitory factor attenuates renal fibrosis through Stat3-miR-29c
Q26777122Leukocytes: The Double-Edged Sword in Fibrosis
Q43777578Lineage tracing and genetic ablation of ADAM12(+) perivascular cells identify a major source of profibrotic cells during acute tissue injury
Q33747884Linking optics and mechanics in an in vivo model of airway fibrosis and epithelial injury
Q93103164Links between Fibrogenesis and Cancer: Mechanistic and Therapeutic Challenges
Q41894153Lipopolysaccharide induces a fibrotic-like phenotype in endothelial cells
Q57640526Lipopolysaccharide influences on the toxicity of oxidised multiwalled carbon nanotubes to murine splenocytesin vitro
Q37109402Liver Injury and the Activation of the Hepatic Myofibroblasts
Q30359290Liver fibrosis and Gd-EOB-DTPA-enhanced MRI: A histopathologic correlation
Q38014650Liver fibrosis: a bidirectional model of fibrogenesis and resolution.
Q34159097Liver fibrosis: an intravoxel incoherent motion (IVIM) study
Q91942500Liver, Tumor and Viral Hepatitis: Key Players in the Complex Balance Between Tolerance and Immune Activation
Q33438643Living-cell microarrays
Q41879637Localization of ανβ6 integrin-TGF-β1/Smad3, mTOR and PPARγ in experimental colorectal fibrosis
Q46405828Long non-coding RNA CHCHD4P4 promotes epithelial-mesenchymal transition and inhibits cell proliferation in calcium oxalate-induced kidney damage
Q34117553Long-term alterations of cytokines and growth factors expression in irradiated tissues and relation with histological severity scoring
Q58590513Long-term effectiveness of local BM-MSCs for skeletal muscle regeneration: a proof of concept obtained on a pig model of severe radiation burn
Q38880396Long-term efficacy and tolerability of mycophenolate mofetil therapy in diffuse scleroderma skin disease.
Q58699037Losartan Alleviates Renal Fibrosis and Inhibits Endothelial-to-Mesenchymal Transition (EMT) Under High-Fat Diet-Induced Hyperglycemia
Q35744613Losartan reduces trinitrobenzene sulphonic acid-induced colorectal fibrosis in rats
Q50116500Loss of CDKN2B Promotes Fibrosis via Increased Fibroblast Differentiation Rather Than Proliferation.
Q43272251Loss of renal microvascular integrity in postnatal Crim1 hypomorphic transgenic mice
Q36749958Loss of steroid receptor co-activator-3 attenuates carbon tetrachloride-induced murine hepatic injury and fibrosis
Q58803095Loureirin B inhibits the proliferation of hepatic stellate cells and the Wnt/β-catenin signaling pathway by regulating miR-148-3p
Q64084650Low Density Lipoprotein Receptor-Related Protein-1 in Cardiac Inflammation and Infarct Healing
Q47130392Low density lipoprotein - rosiglitazone - chitosan-calcium alginate/nanoparticles inhibition of human tenon's fibroblasts activation and proliferation
Q42696954Low oxygen tension positively influences cardiomyocyte progenitor cell function
Q34470104Low-level laser therapy decreases renal interstitial fibrosis.
Q27302984Lung Transcriptomics during Protective Ventilatory Support in Sepsis-Induced Acute Lung Injury
Q58571239Lung fibroblasts express a miR-19a-19b-20a sub-cluster to suppress TGF-β-associated fibroblast activation in murine pulmonary fibrosis
Q50142593Lymphocytes contribute to biliary injury and fibrosis in experimental xenobiotic-induced cholestasis.
Q35736010Lysophosphatidic acid mediates fibrosis in injured joints by regulating collagen type I biosynthesis.
Q37857284Lysophosphatidic acid-1-receptor targeting agents for fibrosis.
Q36680112M10, a caspase cleavage product of the hepatocyte growth factor receptor, interacts with Smad2 and demonstrates antifibrotic properties in vitro and in vivo
Q36437997MBNL1-mediated regulation of differentiation RNAs promotes myofibroblast transformation and the fibrotic response
Q35889180MEK-ERK pathway modulation ameliorates pulmonary fibrosis associated with epidermal growth factor receptor activation
Q37811895MET signalling: principles and functions in development, organ regeneration and cancer
Q60909538MET/HGF Co-Targeting in Pancreatic Cancer: A Tool to Provide Insight into the Tumor/Stroma Crosstalk
Q99566895MFGE8 is down-regulated in cardiac fibrosis and attenuates endothelial-mesenchymal transition through Smad2/3-Snail signalling pathway
Q33623144MLN4924 protects against bleomycin-induced pulmonary fibrosis by inhibiting the early inflammatory process
Q35078509MMP mediated degradation of type IV collagen alpha 1 and alpha 3 chains reflects basement membrane remodeling in experimental and clinical fibrosis--validation of two novel biomarker assays
Q54911489MMP-2 and MMP-9 activities and TIMP-1 and TIMP-2 expression in the prostatic tissue of two ethanol-preferring rat models.
Q33858748MRI-based estimation of liver function: Gd-EOB-DTPA-enhanced T1 relaxometry of 3T vs. the MELD score
Q35687488MUCOSAL IMMUNOLOGY. The microbiota regulates type 2 immunity through RORγt⁺ T cells
Q39125397Macrophage heterogeneity and renin-angiotensin system disorders.
Q36369742Macrophage imbalance (M1 vs. M2) and upregulation of mast cells in wall of ruptured human cerebral aneurysms: preliminary results
Q57801720Macrophage migration inhibitory factor contributes to the pathogenesis of benign lymphoepithelial lesion of the lacrimal gland
Q36610415Macrophage plasticity and the role of inflammation in skeletal muscle repair
Q37990243Macrophage polarization: an opportunity for improved outcomes in biomaterials and regenerative medicine
Q28084850Macrophage responses to implants: prospects for personalized medicine
Q26774649Macrophages During the Fibrotic Process: M2 as Friend and Foe
Q33793909Macrophages and fibroblasts during inflammation and tissue repair in models of organ regeneration.
Q33694114Macrophages are necessary for epimorphic regeneration in African spiny mice.
Q34345718Macrophages are required for adult salamander limb regeneration
Q34847925Macrophages are required for host survival in experimental urogenital schistosomiasis
Q39331723Macrophages as Effectors of Acute and Chronic Allograft Injury
Q40138821Macrophages commit postnatal endothelium-derived progenitors to angiogenesis and restrict endothelial to mesenchymal transition during muscle regeneration.
Q34518415Macrophages in Tissue Repair, Regeneration, and Fibrosis
Q49609112Macrophages: Key orchestrators of a tumor microenvironment defined by therapeutic resistance.
Q34076279Macrophages: master regulators of inflammation and fibrosis
Q39203728Magnetoelastic vibrational biomaterials for real-time monitoring and modulation of the host response
Q26827231Management of fibrosis: the mesenchymal stromal cells breakthrough
Q46362609Mast cell chymase protects against renal fibrosis in murine unilateral ureteral obstruction
Q46028248Master regulators in primary skin fibroblast fate reprogramming in a human ex vivo model of chronic wounds.
Q35947519Matrix Metalloproteinase Mediated Type I Collagen Degradation - An Independent Risk Factor for Mortality in Women.
Q37589790Matrix Metalloproteinases and Tissue Inhibitor of Metalloproteinases in Inflammation and Fibrosis of Skeletal Muscles
Q37150483Matrix control of scarring.
Q35125630Matrix metalloproteinase 9 secreted by hypoxia cardiac fibroblasts triggers cardiac stem cell migration in vitro
Q55097343Matrix metalloproteinase-14 is a biomarker of angiogenic activity in proliferative diabetic retinopathy.
Q85789375Matrix remodeling response of human periodontal tissue cells toward fibrosis upon nicotine exposure
Q37331561Mature adult dystrophic mouse muscle environment does not impede efficient engrafted satellite cell regeneration and self-renewal.
Q33643242MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis
Q51423153Measurement of liver T₁ and T₂ relaxation times in an experimental mouse model of liver fibrosis.
Q42861912Mechanical offloading of incisional wounds is associated with transcriptional downregulation of inflammatory pathways in a large animal model
Q54982400Mechanical signaling through the discoidin domain receptor 1 plays a central role in tissue fibrosis.
Q89724754Mechanisms of Cannabinoids and Potential Applicability to Skin Diseases
Q29620307Mechanisms of fibrosis: therapeutic translation for fibrotic disease
Q28079649Mechanisms of mesenchymal stem/stromal cell function
Q34325432Mechanisms of radiation-induced normal tissue toxicity and implications for future clinical trials
Q33754181Mechanisms that mediate the development of fibrosis in patients with Crohn's disease
Q26740308Mechanoregulation of Wound Healing and Skin Homeostasis
Q38415445Mechanotransduction map: simulation model, molecular pathway, gene set.
Q47318940Mechanotransduction-modulated fibrotic microniches reveal the contribution of angiogenesis in liver fibrosis.
Q34159587Mediators leading to fibrosis - how to measure and control them in tissue engineering.
Q36191671Memory CD8+ T cells are sufficient to alleviate impaired host resistance to influenza A virus infection caused by neonatal oxygen supplementation
Q39036654Meprin β contributes to collagen deposition in lung fibrosis
Q41855310Mesenchymal cell survival in airway and interstitial pulmonary fibrosis
Q42007158Mesenchymal stem cell-mediated suppression of hypertrophic scarring is p53 dependent in a rabbit ear model
Q37536886Mesenchymal stem cells: innovative therapeutic tools for rheumatic diseases.
Q47261430Mesenchymal stromal cells prevent bleomycin-induced lung and skin fibrosis in aged mice and restore wound healing.
Q36752368Metabolic reprogramming and inflammation act in concert to control vascular remodeling in hypoxic pulmonary hypertension
Q35577477Metchnikoff's policemen: macrophages in development, homeostasis and regeneration
Q37452352Mfge8 diminishes the severity of tissue fibrosis in mice by binding and targeting collagen for uptake by macrophages
Q41073242MiRNA-21 promotes fibrosis in orbital fibroblasts from thyroid-associated ophthalmopathy
Q37745389MiRNA199a-3p suppresses tumor growth, migration, invasion and angiogenesis in hepatocellular carcinoma by targeting VEGFA, VEGFR1, VEGFR2, HGF and MMP2.
Q35251059MicroRNA 181b regulates decorin production by dermal fibroblasts and may be a potential therapy for hypertrophic scar
Q34252230MicroRNA expression abnormalities in limited cutaneous scleroderma and diffuse cutaneous scleroderma
Q89043624MicroRNA-21a-5p promotes fibrosis in spinal fibroblasts after mechanical trauma
Q36249425MicroRNAs as potential targets for progressive pulmonary fibrosis
Q28067380MicroRNAs in fibrosis: opportunities and challenges
Q54484920Microarray analysis of Dupuytren's disease cells: the profibrogenic role of the TGF-β inducible p38 MAPK pathway.
Q33827977Microarray analysis of differentially expressed genes in L929 mouse fibroblast cells exposed to leptin and hypoxia
Q36122424Microarray expression analysis and identification of serum biomarkers for Niemann-Pick disease, type C1.
Q34040933Microarray profiling reveals the integrated stress response is activated by halofuginone in mammary epithelial cells
Q38981232Microbes Are Associated with Host Innate Immune Response in Idiopathic Pulmonary Fibrosis
Q38153432Microdeformation in wound healing
Q38165635Microdialysis sampling techniques applied to studies of the foreign body reaction
Q90414220Microenvironmental Alterations in Carbon Nanotube-Induced Lung Inflammation and Fibrosis
Q36455290Migratory CD103+ dendritic cells suppress helminth-driven type 2 immunity through constitutive expression of IL-12
Q38119546Mineralocorticoid receptors and the heart, multiple cell types and multiple mechanisms: a focus on the cardiomyocyte.
Q36723373Mitigation of myocardial fibrosis by molecular cardiac surgery-mediated gene overexpression
Q27312202Modulation of wound healing and scar formation by MG53 protein-mediated cell membrane repair.
Q48176161Molecular Magnetic Resonance Imaging of Lung Fibrogenesis with an Oxyamine-Based Probe
Q55497904Molecular Mechanisms and Treatment of Radiation-Induced Lung Fibrosis.
Q59821288Molecular Probes for Imaging Fibrosis and Fibrogenesis
Q38767584Molecular and Immunological Basis of Tubulo-Interstitial Injury in Lupus Nephritis: a Comprehensive Review.
Q53337186Molecular and cellular mechanisms of glucagon-like peptide-1 receptor agonist-mediated attenuation of cardiac fibrosis.
Q52643365Molecular and histomorphological evaluation of female rats' urethral tissues after an innovative trauma model of prolonged vaginal distention: immediate, short-term and long-term effects.
Q38121751Molecular basis of organ fibrosis: potential therapeutic approaches
Q90348644Molecular determinants of mesenchymal cell activation in fibroproliferative diseases
Q42230916Molecular imaging of oxidized collagen quantifies pulmonary and hepatic fibrogenesis
Q27692609Molecular mechanism and treatment of viral hepatitis-related liver fibrosis
Q34142102Molecular mechanisms and treatment of radiation-induced lung fibrosis
Q42185518Molecular mechanisms of endothelial to mesenchymal cell transition (EndoMT) in experimentally induced fibrotic diseases
Q38032835Molecular serum markers of liver fibrosis.
Q39369473Molecular targets of dietary phytochemicals for possible prevention and therapy of uterine fibroids: Focus on fibrosis.
Q34854719Monocyte chemoattractant protein-1 deficiency does not affect steatosis or inflammation in livers of mice fed a methionine-choline-deficient diet
Q38956732Monocyte chemotactic protein-1 (MCP-1/CCL2) is associated with prostatic growth dysregulation and benign prostatic hyperplasia
Q42097897Monocytic fibroblast precursors mediate fibrosis in angiotensin-II-induced cardiac hypertrophy
Q36017652Morphological Retrospective Study of Peritoneal Biopsies from Patients with Encapsulating Peritoneal Sclerosis: Underestimated Role of Adipocytes as New Fibroblasts Lineage?
Q36102198Multidimensional vocal assessment after laser treatment for recurrent respiratory papillomatosis.
Q35641181Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition
Q33576976Multivariable analysis of risk factors for enlargement of the tracheoesophageal puncture after total laryngectomy
Q45266023Multiwall carbon nanotubes mediate macrophage activation and promote pulmonary fibrosis through TGF-β/Smad signaling pathway
Q50890635Murine Dermal Fibroblast Isolation by FACS.
Q27011291Musculoskeletal regeneration and its implications for the treatment of tendinopathy
Q97595650Mutations in COMP cause familial carpal tunnel syndrome
Q34192783Mutations in fibrillin-1 cause congenital scleroderma: stiff skin syndrome
Q31083702MyD88-dependent signaling influences fibrosis and alternative macrophage activation during Staphylococcus aureus biofilm infection
Q38829400Mycophenolic acid reverses TGF beta-induced cell motility, collagen matrix contraction and cell morphology in vitro
Q92155348Myeloid Differentiation Protein 2 Mediates Angiotensin II-Induced Liver Inflammation and Fibrosis in Mice
Q37398699Myocardial Infarction Alters Adaptation of the Tethered Mitral Valve.
Q35174325Myocardial T1 mapping: techniques and potential applications
Q45832826Myocardial fibrosis in response to Angiotensin II is preceded by the recruitment of mesenchymal progenitor cells
Q38596113Myocardial interstitial remodelling in non-ischaemic dilated cardiomyopathy: insights from cardiovascular magnetic resonance.
Q37641749Myocardial remodeling after infarction: the role of myofibroblasts
Q35626103Myocardin-related transcription factor-A complexes activate type I collagen expression in lung fibroblasts.
Q50522901Myofibroblast persistence and collagen type I accumulation in the human stenotic trachea.
Q39063947Myofibroblast repair mechanisms post-inflammatory response: a fibrotic perspective
Q38294134Myofibroblast secretome and its auto-/paracrine signaling
Q38064729Myofibroblast-mediated mechanisms of pathological remodelling of the heart
Q42504323Myofibroblasts Are Evidence of Chronic Tissue Microtrauma at the Endometrial-Myometrial Junctional Zone in Uteri With Adenomyosis
Q27969008Myofibroblasts and lung fibrosis induced by carbon nanotube exposure
Q42503590Myofibroblasts could be recruited in a chemokine (C-C motif) ligand 2-dependent manner in pathogenesis of oral submucous fibrosis
Q27692541Myofibroblasts: trust your heart and let fate decide.
Q89779500N-Acetyl-L-Cysteine Reduces Fibrosis and Improves Muscle Function After Acute Compartment Syndrome Injury
Q34495678NADPH oxidase 4 is expressed in pulmonary artery adventitia and contributes to hypertensive vascular remodeling
Q33705075NADPH oxidase enzymes in skin fibrosis: molecular targets and therapeutic agents
Q47869398NLRP3 participates in the regulation of EMT in bleomycin-induced pulmonary fibrosis
Q42378502NOGO-B promotes EMT in lung fibrosis via MMP14 mediates free TGF-beta1 formation
Q33649864NOX enzymes and pulmonary disease
Q34645331Naja naja atra venom ameliorates pulmonary fibrosis by inhibiting inflammatory response and oxidative stress
Q40487949Negative regulation of lung inflammation and immunopathology by TNF-α during acute influenza infection
Q89630010Neovascularization is a key feature of liver fibrosis progression: anti-angiogenesis as an innovative way of liver fibrosis treatment
Q92276550Nephropathy in Hypertensive Animals Is Linked to M2 Macrophages and Increased Expression of the YM1/Chi3l3 Protein
Q42486965Nestin expression is lost in ventricular fibroblasts during postnatal development of the rat heart and re-expressed in scar myofibroblasts
Q64106971Neuropeptides Substance P and Calcitonin Gene Related Peptide Accelerate the Development and Fibrogenesis of Endometriosis
Q34769969Neurotrophins and neurotrophin receptors in proliferative diabetic retinopathy
Q42711532Neutralization of interleukin-1 beta attenuates silica-induced lung inflammation and fibrosis in C57BL/6 mice
Q35928300New Lives Given by Cell Death: Macrophage Differentiation Following Their Encounter with Apoptotic Leukocytes during the Resolution of Inflammation
Q52595252New and Emerging Treatments for Lymphedema.
Q34720147New concepts of IL-10-induced lung fibrosis: fibrocyte recruitment and M2 activation in a CCL2/CCR2 axis
Q37709579New developments in the therapy of pulmonary fibrosis
Q38388349New dog and new tricks: evolving roles for IL-33 in type 2 immunity
Q27001340New insights into the morphogenic role of stromal cells and their relevance for regenerative medicine. lessons from the heart
Q33560989New molecular medicine-based scar management strategies
Q38246640New renal drug development to face chronic renal disease
Q59796154Ninjurin1 Plays a Crucial Role in Pulmonary Fibrosis by Promoting Interaction between Macrophages and Alveolar Epithelial Cells
Q90621396Nitrated fatty acids: from diet to disease
Q91943325Noninvasive Young's modulus visualization of fibrosis progression and delineation of pancreatic ductal adenocarcinoma (PDAC) tumors using Harmonic Motion Elastography (HME) in vivo
Q91974913Noninvasive assessment of renal fibrosis by magnetic resonance imaging and ultrasound techniques
Q28075809Nonsurgical treatment options in Peyronie's Disease: 2016 update
Q37599394Not just angiotensinases: new roles for the angiotensin-converting enzymes
Q39377055Novel Anti-fibrotic Therapies
Q26738287Novel biomarkers of fibrosis in Crohn's disease
Q28071302Novel concepts in radiation-induced cardiovascular disease.
Q37934994Novel imaging techniques for diffuse myocardial fibrosis.
Q35622533Novel insights into the function and dynamics of extracellular matrix in liver fibrosis
Q36083434Nutrigenomics analysis reveals that copper deficiency and dietary sucrose up-regulate inflammation, fibrosis and lipogenic pathways in a mature rat model of nonalcoholic fatty liver disease
Q33908275Obesity-induced diabetes and lower urinary tract fibrosis promote urinary voiding dysfunction in a mouse model
Q33808050Obliterative airway remodeling: molecular evidence for shared pathways in transplanted and native lungs
Q33633102Obliterative airway remodelling in transplanted and non-transplanted lungs
Q28067777Ockham's razor for the MET-driven invasive growth linking idiopathic pulmonary fibrosis and cancer
Q45870950Oligonucleotide-targeting periostin ameliorates pulmonary fibrosis.
Q30601730Omega-1 knockdown in Schistosoma mansoni eggs by lentivirus transduction reduces granuloma size in vivo
Q43066618Omental adipose tissue fibrosis and insulin resistance in severe obesity.
Q30485285Oncogenic Ras-transformed human fibroblasts exhibit differential changes in contraction and migration in 3D collagen matrices
Q38763465Ontogeny of Tumor-associated Macrophages and Its Implication in Cancer Regulation
Q28743949Opisthorchiasis and Opisthorchis-associated cholangiocarcinoma in Thailand and Laos
Q35607340Oral administration of marine collagen peptides prepared from chum salmon (Oncorhynchus keta) improves wound healing following cesarean section in rats
Q37903909Oral cancers: supportive care issues
Q37124381Oral serum-derived bovine immunoglobulin improves duodenal immune reconstitution and absorption function in patients with HIV enteropathy
Q46664712Oral tolerance attenuates changes in in vitro lung tissue mechanics and extracellular matrix remodeling induced by chronic allergic inflammation in guinea pigs.
Q26863633Origin of developmental precursors dictates the pathophysiologic role of cardiac fibroblasts
Q41592573Orphan nuclear receptor NR4A1 regulates transforming growth factor-β signaling and fibrosis
Q42469702Osteopontin and other regulators of angiogenesis and fibrogenesis in the vitreous from patients with proliferative vitreoretinal disorders
Q39337824Osteopontin contributes to TGF-β1 mediated hepatic stellate cell activation
Q34839346Osteopontin modulates inflammation, mucin production, and gene expression signatures after inhalation of asbestos in a murine model of fibrosis
Q38839402Overactive Epidermal Growth Factor Receptor Signaling Leads to Increased Fibrosis after Severe Acute Respiratory Syndrome Coronavirus Infection
Q34598380Overexpression of endoglin modulates TGF-β1-signalling pathways in a novel immortalized mouse hepatic stellate cell line
Q42984072Oxidative Stress and Skin Fibrosis
Q46860194Oxidative stress mediates the conversion of endothelial cells into myofibroblasts via a TGF-β1 and TGF-β2-dependent pathway
Q35666941Oxidative/Nitrative Stress and Inflammation Drive Progression of Doxorubicin-Induced Renal Fibrosis in Rats as Revealed by Comparing a Normal and a Fibrosis-Resistant Rat Strain
Q37861626PAI-1 in tissue fibrosis
Q39212450PDGF-A and PDGF-B induces cardiac fibrosis in transgenic mice
Q47102830PDGFR Signaling Mediates Hyperproliferation and Fibrotic Responses of Subsynovial Connective Tissue Cells in Idiopathic Carpal Tunnel Syndrome.
Q41354166PEDF inhibits pancreatic tumorigenesis by attenuating the fibro-inflammatory reaction
Q37550306PHF14: an innate inhibitor against the progression of renal fibrosis following folic acid-induced kidney injury.
Q35507969Paclitaxel attenuates renal interstitial fibroblast activation and interstitial fibrosis by inhibiting STAT3 signaling.
Q43096273Paeoniflorin ameliorates schistosomiasis liver fibrosis through regulating IL-13 and its signalling molecules in mice
Q43631328Paired immunoglobulin-like receptor-B inhibits pulmonary fibrosis by suppressing profibrogenic properties of alveolar macrophages
Q34287169Paricalcitol reduces peritoneal fibrosis in mice through the activation of regulatory T cells and reduction in IL-17 production
Q37195998Partial epithelial-mesenchymal transition in keloid scars: regulation of keloid keratinocyte gene expression by transforming growth factor-β1
Q64072097Participation of NADPH Oxidase-Related Reactive Oxygen Species in Leptin-Promoted Pulmonary Inflammation: Regulation of cPLA2α and COX-2 Expression
Q46038786Participation of functionally different macrophage populations and monocyte chemoattractant protein-1 in early stages of thioacetamide-induced rat hepatic injury.
Q93075393Pathogenesis of fibrostenosing Crohn's disease
Q38222245Pathogenesis of idiopathic pulmonary fibrosis and its clinical implications
Q35310907Pericellular versican regulates the fibroblast-myofibroblast transition: a role for ADAMTS5 protease-mediated proteolysis
Q34357219Pericytes at the intersection between tissue regeneration and pathology
Q92421314Pericytes in Muscular Dystrophies
Q92187715Pericytes: Problems and Promises for CNS Repair
Q34201678Pericytes: multitasking cells in the regeneration of injured, diseased, and aged skeletal muscle
Q52600938Perivascular cell αv integrins as a target to treat skeletal muscle fibrosis.
Q26746998Peroxisome Proliferator-Activated Receptor-γ Is Critical to Cardiac Fibrosis
Q33816291Peroxisome proliferator-activated receptor (PPAR)gamma can inhibit chronic renal allograft damage
Q92844811Petchiether A attenuates obstructive nephropathy by suppressing TGF-β/Smad3 and NF-κB signalling
Q53834988Petroleum coke exposure leads to altered secretome profiles in human lung models.
Q42377201Pharmacological HIF-inhibition attenuates postoperative adhesion formation
Q91792931Pharmacotherapy Agents in Lymphedema Treatment: A Systematic Review
Q37944795Phenytoin-induced gingival overgrowth: a review of the molecular, immune, and inflammatory features.
Q61950120Photoactivatable Hsp47: A Tool to Regulate Collagen Secretion and Assembly
Q39251086Physical and Chemical Gradients in the Tumor Microenvironment Regulate Tumor Cell Invasion, Migration, and Metastasis
Q49216178Physical and chemical microenvironmental cues orthogonally control the degree and duration of fibrosis-associated epithelial-to-mesenchymal transitions.
Q38146936Physiological changes to the swallowing mechanism following (chemo)radiotherapy for head and neck cancer: a systematic review
Q46916695Physiological regulation of MMPs and tPA/PAI in the arterial wall of rats by noradrenergic tone and angiotensin II.
Q38256228Physiopathologic mechanisms involved in mare endometrosis
Q90671891Pigment Epithelium-Derived Factor as a Possible Treatment Agent for Choroidal Neovascularization
Q37627860Pigment epithelium-derived factor attenuates myocardial fibrosis via inhibiting Endothelial-to-Mesenchymal Transition in rats with acute myocardial infarction
Q41126008Pine bark extract (Pycnogenol®) suppresses cigarette smoke-induced fibrotic response via transforming growth factor-β1/Smad family member 2/3 signaling
Q93111317Piperine ameliorates the severity of fibrosis via inhibition of TGF‑β/SMAD signaling in a mouse model of chronic pancreatitis
Q92664052Pirfenidone attenuates lung fibrotic fibroblast responses to transforming growth factor-β1
Q102141552Pirfenidone regulates LPS mediated activation of neutrophils
Q36583294Plakophilin-2 loss promotes TGF-β1/p38 MAPK-dependent fibrotic gene expression in cardiomyocytes.
Q45071763Plasma hydroxyproline, MMP-7 and collagen I as novel predictive risk markers of hepatobiliary disease-associated cholangiocarcinoma
Q51337005Plasma rich in growth factors promotes dermal fibroblast proliferation, migration and biosynthetic activity.
Q37344022Plasminogen activator inhibitor-1 regulates integrin alphavbeta3 expression and autocrine transforming growth factor beta signaling
Q46148909Platelet derived serotonin drives the activation of rat cardiac fibroblasts by 5-HT2A receptors
Q39953619Platelet-rich plasma (PRP) impairs the craniofacial bone repair associated with its elevated TGF-β levels and modulates the co-expression between collagen III and α-smooth muscle actin
Q103826031Pluripotent epigenetic regulator OBP-801 maintains filtering blebs in glaucoma filtration surgery model
Q38444555Porous implants modulate healing and induce shifts in local macrophage polarization in the foreign body reaction.
Q50547237Possible involvement of inflammatory/reparative processes in the development of uterine fibroids.
Q33628879Posttreatment with Protectin DX ameliorates bleomycin-induced pulmonary fibrosis and lung dysfunction in mice
Q90319999Potential of serum microRNAs as biomarkers of radiation injury and tools for individualization of radiotherapy
Q41834482Precision-Cut Kidney Slices as a Tool to Understand the Dynamics of Extracellular Matrix Remodeling in Renal Fibrosis.
Q38842130Predicting pulmonary fibrosis in humans after exposure to multi-walled carbon nanotubes (MWCNTs).
Q36125412Premature expression of a muscle fibrosis axis in chronic HIV infection
Q30596295Prestress in the extracellular matrix sensitizes latent TGF-β1 for activation.
Q35025496Prevalence, hemodynamics, and cytokine profile of effusive-constrictive pericarditis in patients with tuberculous pericardial effusion
Q35072681Preventive effect of halofuginone on concanavalin A-induced liver fibrosis
Q40902938Primary mouse lung fibroblasts help macrophages to tackle Mycobacterium tuberculosis more efficiently and differentiate into myofibroblasts up on bacterial stimulation
Q89717434Principles of Cell Circuits for Tissue Repair and Fibrosis
Q43068331Pro- and anti-inflammatory cytokines in steatosis and steatohepatitis
Q42126549Procollagen Lysyl Hydroxylase 2 Expression Is Regulated by an Alternative Downstream Transforming Growth Factor β-1 Activation Mechanism
Q86672660Profibrosing effect of angiotensin converting enzyme inhibitors in human lung fibroblasts
Q90639907Prominence of IL6, IGF, TLR, and Bioenergetics Pathway Perturbation in Lung Tissues of Scleroderma Patients With Pulmonary Fibrosis
Q37364472Promising molecular targets and biomarkers for male BPH and LUTS
Q51835859Properties and Immune Function of Cardiac Fibroblasts.
Q54257268Prospective of 68Ga Radionuclide Contribution to the Development of Imaging Agents for Infection and Inflammation.
Q38074716Prostanoids receptors signaling in different diseases/cancers progression
Q41595234Prostatic fibrosis is associated with lower urinary tract symptoms
Q34822091Prostatic fibrosis, lower urinary tract symptoms, and BPH
Q38021378Proteases, cystic fibrosis and the epithelial sodium channel (ENaC).
Q36678523Proteasomal inhibition after injury prevents fibrosis by modulating TGF-β(1) signalling
Q90598888Protective Role of Vitamin D in Renal Tubulopathies
Q29620351Protective and pathogenic functions of macrophage subsets
Q33594283Protective effect of astaxanthin on liver fibrosis through modulation of TGF-β1 expression and autophagy.
Q51025454Protective effect of ulinastatin in patients with non-small cell lung cancer after radiation therapy: a randomized, placebo-controlled study.
Q57458063Protein imbalance in the development of skeletal muscle wasting in tumour-bearing mice
Q91893715Proteomic Analysis of Radiation-Induced Acute Liver Damage in a Rabbit Model
Q36602953Proteomic analysis of the effect of fuzheng huayu recipe on fibrotic liver in rats
Q32179716Puerarin attenuates renal fibrosis by reducing oxidative stress induced-epithelial cell apoptosis via MAPK signal pathways in vivo and in vitro
Q42220886Pulmonary antifibrotic mechanisms aspirin-triggered lipoxin A(4) synthetic analog
Q35151307Pulmonary delivery of docosahexaenoic acid mitigates bleomycin-induced pulmonary fibrosis
Q34626008Pulse-chase analysis of procollagen biosynthesis by azidohomoalanine labeling.
Q35571961Qiliqiangxin inhibits angiotensin II-induced transdifferentiation of rat cardiac fibroblasts through suppressing interleukin-6
Q35966131Quantitative Three-Dimensional Imaging of Lipid, Protein, and Water Contents via X-Ray Phase-Contrast Tomography
Q61172884Quantitative assessment of intestinal stiffness and associations with fibrosis in human inflammatory bowel disease
Q35029642Quantitative assessment of macrophage functions in repair and fibrosis
Q87929596R-spondin2 activates hepatic stellate cells and promotes liver fibrosis
Q42368982R1R2 peptide ameliorates pulmonary fibrosis in mice through fibrocyte migration and differentiation
Q57458560RAAS inhibitors directly reduce diabetes-induced renal fibrosis via growth factor inhibition.
Q33510140Rac inhibition reverses the phenotype of fibrotic fibroblasts
Q37777878Radiation Pulmonary Toxicity: From Mechanisms to Management
Q34513806Radiation fibrosis of the vocal fold: from man to mouse.
Q34149752Radiation therapy causes loss of dermal lymphatic vessels and interferes with lymphatic function by TGF-beta1-mediated tissue fibrosis
Q45058787Radiation-Induced Fibrosis: Mechanisms and Opportunities to Mitigate. Report of an NCI Workshop, September 19, 2016.
Q36750137Radiation-induced lung injury is mitigated by blockade of gastrin-releasing peptide.
Q58696764Radiation-induced muscle fibrosis rat model: establishment and valuation
Q38761174Radiogenomics: A systems biology approach to understanding genetic risk factors for radiotherapy toxicity?
Q95406381Radiotherapy toxicity
Q33632810Radiotherapy-Induced Skin Reactions Induce Fibrosis Mediated by TGF-β1 Cytokine
Q37264534Ramipril attenuates left ventricular remodeling by regulating the expression of activin A-follistatin in a rat model of heart failure
Q84020876Rapid quantification of myocardial fibrosis: a new macro-based automated analysis
Q36335937Rapid tissue regeneration induced by intracellular ATP delivery-A preliminary mechanistic study.
Q64259452Reactive Oxygen Species Drive Epigenetic Changes in Radiation-Induced Fibrosis
Q98471309Recapitulation of normal collagen architecture in embryonic wounded corneas
Q39303904Recent Advances in Magnetic Resonance Imaging Assessment of Renal Fibrosis
Q26773161Recent Treatments of Interstitial Lung Disease with Systemic Sclerosis
Q50042214Recent Updates on Treatment of Ocular Microbial Infections by Stem Cell Therapy: A Review.
Q30414378Recent advances in molecular magnetic resonance imaging of liver fibrosis
Q37204019Recent advances in the pathogenesis and diagnosis of liver fibrosis
Q35528061Recruited exudative macrophages selectively produce CXCL10 after noninfectious lung injury
Q50457515Recruitment and subsequent proliferation of bone marrow-derived cells in the postischemic kidney are important to the progression of fibrosis.
Q38229320Recurrent HCV after liver transplantation-mechanisms, assessment and therapy
Q38202115Redox signaling as a therapeutic target to inhibit myofibroblast activation in degenerative fibrotic disease
Q42174211Reduction of conjunctival fibrosis after trabeculectomy using topical α-lipoic acid in rabbit eyes
Q92661408Reduction of liver fibrosis by rationally designed macromolecular telmisartan prodrugs
Q85646545Regeneration of functional pronephric proximal tubules after partial nephrectomy in Xenopus laevis
Q31113958Regeneration of soft tissues is promoted by MMP1 treatment after digit amputation in mice
Q37767061Regulation and dysregulation of fibrosis in skeletal muscle
Q42877527Regulation of Macrophage Polarization and Wound Healing
Q37377434Regulation of pathogenesis and immunity in helminth infections
Q37269243Regulation of platelet-derived growth factor receptor function by integrin-associated cell surface transglutaminase
Q91898704Regulatory T Cells in Respiratory Health and Diseases
Q47412936Regulatory role of miR-18a to CCN2 by TGF-β1 signaling pathway in pulmonary injury induced by nano-SiO2.
Q64271648Relationships Between Phenotype and Function of Blood CD4+ T-Cells and Ascending Thoracic Aortic Aneurysm: an Experimental Study
Q50665394Relaxin requires the angiotensin II type 2 receptor to abrogate renal interstitial fibrosis.
Q34398874Relaxin signals through a RXFP1-pERK-nNOS-NO-cGMP-dependent pathway to up-regulate matrix metalloproteinases: the additional involvement of iNOS.
Q35033650Renal denervation prevents long-term sequelae of ischemic renal injury
Q24657528Renal fibrosis
Q37641420Renal ischemia/reperfusion-induced cardiac hypertrophy in mice: Cardiac morphological and morphometric characterization
Q36574766Renal nerves drive interstitial fibrogenesis in obstructive nephropathy.
Q38530466Renal risk associated with sodium phosphate medication: safe in healthy individuals, potentially dangerous in others
Q37662113Renal tubular epithelium-targeted peroxisome proliferator-activated receptor-γ maintains the epithelial phenotype and antagonizes renal fibrogenesis
Q37368710Renal tubulointerstitial fibrosis: common but never simple.
Q90576869Renin-angiotensin system in human coronavirus pathogenesis
Q37499439Repair Potential of Matrix-Induced Bone Marrow Aspirate Concentrate and Matrix-Induced Autologous Chondrocyte Implantation for Talar Osteochondral Repair: Patterns of Some Catabolic, Inflammatory, and Pain Mediators
Q40107399Repetitive Intradermal Bleomycin Injections Evokes T Helper Cell 2 Cytokine-driven Pulmonary Fibrosis
Q64103031Resolvin D1 prevents epithelial-mesenchymal transition and reduces the stemness features of hepatocellular carcinoma by inhibiting paracrine of cancer-associated fibroblast-derived COMP
Q24292825Response gene to complement 32 interacts with Smad3 to promote epithelial-mesenchymal transition of human renal tubular cells
Q28588339Response gene to complement 32 is essential for fibroblast activation in renal fibrosis
Q90221459Response of Human Macrophages to Clinically Applied Wound Dressings Loaded With Silver
Q41468014Response of fibroblasts to transforming growth factor-β1 on two-dimensional and in three-dimensional hyaluronan hydrogels
Q44817032Restoration of muscle strength in dystrophic muscle by angiotensin-1-7 through inhibition of TGF-β signalling
Q37707648Restorative effects of hydroxysafflor yellow A on hepatic function in an experimental regression model of hepatic fibrosis induced by carbon tetrachloride
Q26782048Restoring homeostasis of CD4⁺ T cells in hepatitis-B-virus-related liver fibrosis
Q37992246Results of the 2nd scientific workshop of the ECCO (III): basic mechanisms of intestinal healing.
Q23923914Resveratrol inhibits paraquat-induced oxidative stress and fibrogenic response by activating the Nrf2 pathway
Q36066095Resveratrol-Mediated Repression and Reversion of Prostatic Myofibroblast Phenoconversion.
Q36999832Reversal of myofibroblast differentiation by prostaglandin E(2).
Q61807550Reversion of in vivo fibrogenesis by novel chromone scaffolds
Q38218544Review article: the efficacy of biomarkers in chronic fibroproliferative diseases - early diagnosis and prognosis, with liver fibrosis as an exemplar.
Q38956376Review: Frontiers of Antifibrotic Therapy in Systemic Sclerosis
Q47133379Review: Metabolic Control of Immune System Activation in Rheumatic Diseases
Q38044467Review: immune-mediated necrotizing myopathies--a heterogeneous group of diseases with specific myopathological features
Q93157685Rhein alleviates renal interstitial fibrosis by inhibiting tubular cell apoptosis in rats
Q36022483Rictor/mTORC2 signaling mediates TGFβ1-induced fibroblast activation and kidney fibrosis
Q38177241Risk biomarkers for assessment and chemoprevention of liver fluke-associated cholangiocarcinoma
Q26768585Role of Bone Marrow-Derived Fibroblasts in Renal Fibrosis
Q54323819Role of MAPK signal pathways in differentiation process of M2 macrophages induced by high-ambient glucose and TGF-β1.
Q36093326Role of MicroRNAs in Fibrosis
Q37452120Role of PDGFs/PDGFRs signaling pathway in myocardial fibrosis of DOCA/salt hypertensive rats
Q92097260Role of complement 3 in the pathogenesis of hypertension
Q37224668Role of endothelial to mesenchymal transition in the pathogenesis of the vascular alterations in systemic sclerosis
Q35168217Role of endothelial-mesenchymal transition (EndoMT) in the pathogenesis of fibrotic disorders
Q35838867Role of integrin-β3 protein in macrophage polarization and regeneration of injured muscle
Q34360300Role of interleukin-13 in fibrosis, particularly systemic sclerosis
Q38206408Role of interleukin-6 in regulation of immune responses to remodeling after myocardial infarction
Q40257840Role of matrix metalloproteinases in radiation-induced lung injury in alveolar epithelial cells of Bama minipigs
Q36775830Role of microRNAs in gastrointestinal smooth muscle fibrosis and dysfunction: novel molecular perspectives on the pathophysiology and therapeutic targeting
Q38848481Role of microRNAs in the Therapeutic Effects of Curcumin in Non-Cancer Diseases
Q37771768Role of myofibroblasts in vascular remodelling: focus on restenosis and aneurysm.
Q39423496Role of nuclear factor kappa-B in phenytoin-induced gingival overgrowth
Q24634546Role of pericytes in skeletal muscle regeneration and fat accumulation
Q38096495Role of proteoglycans in the regulation of the skeletal muscle fibrotic response.
Q38879747Role of renin-angiotensin system in liver diseases: an outline on the potential therapeutic points of intervention.
Q26747017Role of the Renin-Angiotensin-Aldosterone System beyond Blood Pressure Regulation: Molecular and Cellular Mechanisms Involved in End-Organ Damage during Arterial Hypertension
Q38083596Role of the endothelial-to-mesenchymal transition in renal fibrosis of chronic kidney disease
Q26999096Role of the lesion scar in the response to damage and repair of the central nervous system
Q33742115Role of the microRNA-29 family in fibrotic skin diseases.
Q36252926Role of γδ T Cells in Lung Inflammation
Q30594252Roles of transforming growth factor-β1 and OB-cadherin in porcine cardiac valve myofibroblast differentiation.
Q54331126Rosiglitazone attenuates activation of human Tenon's fibroblasts induced by transforming growth factor-β1.
Q43198035S-nitroso-N-acetylcysteine attenuates liver fibrosis in cirrhotic rats.
Q36597265SIRT3 Blocks Aging-Associated Tissue Fibrosis in Mice by Deacetylating and Activating Glycogen Synthase Kinase 3β.
Q38905039SMAD3 and SP1/SP3 Transcription Factors Collaborate to Regulate Connective Tissue Growth Factor Gene Expression in Myoblasts in Response to Transforming Growth Factor β.
Q39251967SOCS-3 is downregulated in progressive CKD patients and regulates proliferation in human renal proximal tubule cells in a STAT1/3 independent manner
Q33702390Satellite cell dysfunction and impaired IGF-1 signaling cause CKD-induced muscle atrophy
Q37856705Scar wars: mapping the fate of epithelial-mesenchymal-myofibroblast transition
Q38187978Scarless wound healing
Q38852162Scarless wound healing: finding the right cells and signals
Q83155917Scarred by disease
Q64098812Schistosome infection and its effect on pulmonary circulation
Q37872589Scraping fibrosis: expressway to the core of fibrosis
Q42723938Screening for antifibrotic compounds using high throughput system based on fluorescence polarization
Q53132495Secondary biliary cirrhosis in the rat is prevented by decreasing NF-κB nuclear translocation and TGF-β expression using allopurinol, an inhibitor of xanthine oxidase.
Q35749231Secreted protein acidic and rich in cysteine facilitates age-related cardiac inflammation and macrophage M1 polarization.
Q33613035Selective measurement of α smooth muscle actin: why β-actin can not be used as a housekeeping gene when tissue fibrosis occurs.
Q52837772Serum Decorin, Interleukin-1β, and Transforming Growth Factor-β Predict Hypertrophic Scarring Postburn.
Q92617180Serum miR-21 correlates with the histological stage of chronic hepatitis B-associated liver fibrosis
Q91235944Shared and distinct mechanisms of fibrosis
Q34385825Significance of vasculopathy in IgA nephropathy patients with regard to Oxford classification and immunostaining findings: a single center experience
Q37660726Significant contribution of TRPC6 channel-mediated Ca2+ influx to the pathogenesis of Crohn's disease fibrotic stenosis
Q35359339Simultaneous application of bevacizumab and anti-CTGF antibody effectively suppresses proangiogenic and profibrotic factors in human RPE cells
Q36066400Simultaneous deletion of Bax and Bak is required to prevent apoptosis and interstitial fibrosis in obstructive nephropathy
Q35063762Simultaneous transcriptional profiling of bacteria and their host cells
Q31142754Skeletal Muscle Quantitative Nuclear Magnetic Resonance Imaging and Spectroscopy as an Outcome Measure for Clinical Trials
Q38860573Skeletal muscle fibroblasts in health and disease
Q37383098Skin fibrosis. Identification and isolation of a dermal lineage with intrinsic fibrogenic potential
Q34383439Skin wound healing and scarring: fetal wounds and regenerative restitution
Q50000565Smad3-STAT3 crosstalk in pathophysiological contexts.
Q55240535Soluble Mediators Produced by Pro-Resolving Macrophages Inhibit Angiogenesis.
Q37596197Sophocarpine attenuates liver fibrosis by inhibiting the TLR4 signaling pathway in rats
Q39134223Sp1 mediates microRNA-29c-regulated type I collagen production in renal tubular epithelial cells
Q35138620Space radiation-associated lung injury in a murine model
Q34921823Sphingolipids in pulmonary fibrosis
Q33753317Sphingosine 1-Phosphate Receptors: Do They Have a Therapeutic Potential in Cardiac Fibrosis?
Q54119596Sphingosine kinase 1 promotes liver fibrosis by preventing miR-19b-3p-mediated inhibition of CCR2.
Q37176189Sphingosine-1-phosphate and sphingosine kinase are critical for transforming growth factor-beta-stimulated collagen production by cardiac fibroblasts
Q36130909Sprouty is a negative regulator of transforming growth factor β-induced epithelial-to-mesenchymal transition and cataract.
Q40159797Src family kinases in chronic kidney disease
Q35033196Staphylococcus aureus biofilms prevent macrophage phagocytosis and attenuate inflammation in vivo
Q38046544Stem cell transplantation as a therapy for cardiac fibrosis.
Q55401793Stem/Stromal Cells for Treatment of Kidney Injuries With Focus on Preclinical Models.
Q38066022Steroid regulation of menstrual bleeding and endometrial repair
Q38963936Steroid-induced ocular hypertension/glaucoma: Focus on pharmacogenomics and implications for precision medicine
Q27347907Stiffening hydrogels for investigating the dynamics of hepatic stellate cell mechanotransduction during myofibroblast activation
Q35923079Stromal fibroblast-bone marrow-derived cell interactions: implications for myofibroblast development in the cornea
Q34390606Stromal liver kinase B1 [STK11] signaling loss induces oviductal adenomas and endometrial cancer by activating mammalian Target of Rapamycin Complex 1.
Q51542269Subset-specific alterations in frequencies and functional signatures of γδ T cells in systemic sclerosis patients.
Q43174220Successful treatment with tacrolimus of progressive interstitial pneumonia associated with amyopathic dermatomyositis refractory to cyclosporine
Q50280511Sulforaphane mitigates muscle fibrosis in mdx mice via Nrf2-mediated inhibition of TGF-β/Smad signaling.
Q37160141Superoxide overproduction and kidney fibrosis: a new animal model.
Q39528046Suppression of Nrf2 signaling by angiotensin II in murine renal epithelial cells
Q36288420Suppression of TGF-β pathway by pirfenidone decreases extracellular matrix deposition in ocular fibroblasts in vitro
Q28482696Suramin alleviates glomerular injury and inflammation in the remnant kidney
Q35012404Suramin inhibits renal fibrosis in chronic kidney disease.
Q85208809Suramin inhibits the development and progression of peritoneal fibrosis
Q28536943Suramin: a potential therapy for diabetic nephropathy
Q34373111Surgical approaches to create murine models of human wound healing
Q35621434Survivin expression induced by endothelin-1 promotes myofibroblast resistance to apoptosis
Q36682162Sustained PI3K Activation exacerbates BLM-induced Lung Fibrosis via activation of pro-inflammatory and pro-fibrotic pathways
Q55397863Swallowing Exercises: Will They Really Help Head and Neck Cancer Patients?
Q23910477System-based identification of toxicity pathways associated with multi-walled carbon nanotube-induced pathological responses
Q28546811Systemic Delivery of scAAV8-Encoded MiR-29a Ameliorates Hepatic Fibrosis in Carbon Tetrachloride-Treated Mice
Q104607826Systems biology predicts that fibrosis in tuberculous granulomas may arise through macrophage-to-myofibroblast transformation
Q27002418T Helper 17/Regulatory T Cell Balance and Experimental Models of Peritoneal Dialysis-Induced Damage
Q93024028T-Helper 2 Lymphocyte Immunophenotype Is Associated With Iatrogenic Laryngotracheal Stenosis
Q93049089T-cell positioning by chemokines in autoimmune skin diseases
Q40725613TAK1 is a key modulator of the profibrogenic phenotype of human ileal myofibroblasts in Crohn's disease
Q43599859TAK1 is required for dermal wound healing and homeostasis
Q39878170TGF-beta1 induces human bronchial epithelial cell-to-mesenchymal transition in vitro
Q91897242TGF-β in fibrosis by acting as a conductor for contractile properties of myofibroblasts
Q37899212TGF-β signaling in fibrosis
Q53821423TGF-β, Fibronectin and Integrin α5β1 Promote Invasion in Basal Cell Carcinoma.
Q34772461TGF-β1 Suppresses Plasmin and MMP Activity in Flexor Tendon Cells via PAI-1: Implications for Scarless Flexor Tendon Repair.
Q38177343TGF-β1 as a therapeutic target for pulmonary fibrosis and COPD.
Q42759660TGF-β1 induces podocyte injury through Smad3-ERK-NF-κB pathway and Fyn-dependent TRPC6 phosphorylation
Q28732072TGFbeta family members are key mediators in the induction of myofibroblast phenotype of human adipose tissue progenitor cells by macrophages
Q90131166TGFβ-induced fibroblast activation requires persistent and targeted HDAC-mediated gene repression
Q92564621TGFβ1-Smad canonical and -Erk noncanonical pathways participate in interleukin-17-induced epithelial-mesenchymal transition in Sjögren's syndrome
Q42675950TIAM1 inhibits lung fibroblast differentiation in pulmonary fibrosis
Q37739786TLR3 modulates immunopathology during a Schistosoma mansoni egg-driven Th2 response in the lung
Q34124196TLR4 promotes fibrosis but attenuates tubular damage in progressive renal injury
Q35606977TLR9 differentiates rapidly from slowly progressing forms of idiopathic pulmonary fibrosis
Q41324289TNF receptor 1 signaling is critically involved in mediating angiotensin-II-induced cardiac fibrosis
Q52721826TNFSF14 (LIGHT) Exhibits Inflammatory Activities in Lung Fibroblasts Complementary to IL-13 and TGF-β.
Q38935000TRPV4 ion channel is a novel regulator of dermal myofibroblast differentiation
Q53270018Tamoxifen ameliorates renal tubulointerstitial fibrosis by modulation of estrogen receptor α-mediated transforming growth factor-β1/Smad signaling pathway.
Q92736402Targeted Therapies in Surgical Treatment of Lymphedema: A Systematic Review
Q37008372Targeting NOX enzymes in pulmonary fibrosis
Q43238854Targeting TGF-beta1 by employing a vaccine ameliorates fibrosis in a mouse model of chronic colitis
Q89241989Targeting TGFβ Signaling to Address Fibrosis Using Antisense Oligonucleotides
Q99587532Targeting cardiac fibrosis in heart failure with preserved ejection fraction: mirage or miracle?
Q37883929Targeting collagen expression in alcoholic liver disease
Q37770947Targeting fibrosis in Duchenne muscular dystrophy
Q39833975Targeting myofibroblasts in model systems of fibrosis by an artificial alpha-smooth muscle-actin promoter hybrid
Q53544896Telmisartan attenuates peritoneal fibrosis via peroxisome proliferator-activated receptor-γ activation in rats.
Q45895068Telmisartan plus propranolol improves liver fibrosis and bile duct proliferation in the PSC-like Abcb4-/- mouse model
Q38802207Telocytes in Chronic Inflammatory and Fibrotic Diseases
Q38385217Tenascins in fibrotic disorders-from bench to bedside
Q57170896Testing Natural Biomaterials in Animal Models
Q37691158Th17 cells favor inflammatory responses while inhibiting type I collagen deposition by dermal fibroblasts: differential effects in healthy and systemic sclerosis fibroblasts
Q34973340Th17 down-regulation is involved in reduced progression of schistosomiasis fibrosis in ICOSL KO mice
Q37396933Th17-polarized immune response in a murine model of hypersensitivity pneumonitis and lung fibrosis
Q36615191Th2 differentiation is necessary for soft tissue fibrosis and lymphatic dysfunction resulting from lymphedema
Q36260811Th2-biased GATA-3 transgenic mice developed severe experimental peritoneal fibrosis compared with Th1-biased T-bet and Th17-biased RORγt transgenic mice
Q27312584The AMPK agonist AICAR inhibits TGF-β1 induced activation of kidney myofibroblasts
Q38618679The Amniotic Membrane: Development and Potential Applications - A Review.
Q35218947The Angiotensin-converting enzyme inhibitor captopril inhibits poly(adp-ribose) polymerase activation and exerts beneficial effects in an ovine model of burn and smoke injury
Q36904042The CYP2E1 inhibitor DDC up-regulates MMP-1 expression in hepatic stellate cells via an ERK1/2- and Akt-dependent mechanism
Q64101613The Carcinogenic Role of the Notch Signaling Pathway in the Development of Hepatocellular Carcinoma
Q51584895The Combined Use of Losartan and Muscle-Derived Stem Cells Significantly Improves the Functional Recovery of Muscle in a Young Mouse Model of Contusion Injuries.
Q92808191The Design of Potent, Selective and Drug-Like RGD αvβ1 Small-Molecule Inhibitors Derived from non-RGD α4β1 Antagonists
Q61798677The Differential Roles of T Cells in Non-alcoholic Fatty Liver Disease and Obesity
Q91791424The Effect of Low-Power Laser Therapy on the TGF/β Signaling Pathway in Chronic Kidney Disease: A Review
Q26776002The Elusive Antifibrotic Macrophage
Q90546431The Emerging Roles of Nicotinamide Adenine Dinucleotide Phosphate Oxidase 2 in Skeletal Muscle Redox Signaling and Metabolism
Q58719281The Importance of Biophysical and Biochemical Stimuli in Dynamic Skeletal Muscle Models
Q36970134The Influence of Bone Marrow-Secreted IL-10 in a Mouse Model of Cerulein-Induced Pancreatic Fibrosis
Q42101096The IκB kinase inhibitor ACHP strongly attenuates TGFβ1-induced myofibroblast formation and collagen synthesis
Q42080118The Jeremiah Metzger lecture. The origin of fibroblasts and the terminality of epithelial differentiation
Q38173382The Juxtacanalicular Region of Ocular Trabecular Meshwork: A Tissue with a Unique Extracellular Matrix and Specialized Function
Q64104639The MicroRNA miR-155 Is Essential in Fibrosis
Q64095050The Molecular Mechanism of Transforming Growth Factor-β Signaling for Intestinal Fibrosis: A Mini-Review
Q36652097The NRF2-heme oxygenase-1 system modulates cyclosporin A-induced epithelial-mesenchymal transition and renal fibrosis
Q37784810The Orbital Fibroblast: A Key Player and Target for Therapy in Graves’ Ophthalmopathy
Q91659694The PPARγ agonist pioglitazone prevents TGF-β induced renal fibrosis by repressing EGR-1 and STAT3
Q42694416The Processes and Mechanisms of Cardiac and Pulmonary Fibrosis
Q92188777The Proinflammatory and Proangiogenic Macrophage Migration Inhibitory Factor Is a Potential Regulator in Proliferative Diabetic Retinopathy
Q38129218The RESOLVE concept: approaching pathophysiology of fibroproliferative disease in aged individuals
Q36407662The Relationship between Proliferative Scars and Endothelial Function in Surgically Revascularized Patients.
Q37505068The Role of Adipocytes in Tissue Regeneration and Stem Cell Niches
Q92528775The Role of Mesenchymal Stem Cells in Radiation-Induced Lung Fibrosis
Q38524619The Role of PPAR Gamma in Systemic Sclerosis
Q38602815The Role of Tyrosine Kinase Receptors in Peritoneal Fibrosis
Q89966619The Role of the Anti-Inflammatory Cytokine Interleukin-10 in Tissue Fibrosis
Q52727884The Role of the Mammalian Target of Rapamycin (mTOR) in Pulmonary Fibrosis.
Q41975783The Role of the NLRP3 Inflammasome in Fibrosis
Q47112999The SOD Mimic, MnTE-2-PyP, Protects from Chronic Fibrosis and Inflammation in Irradiated Normal Pelvic Tissues
Q49265933The TGF-β System As a Potential Pathogenic Player in Disease Modulation of Amyotrophic Lateral Sclerosis.
Q57538743The Use of Human Mesenchymal Stem Cells as Therapeutic Agents for the Treatment of Immune-Related Diseases: A Systematic Review
Q35989481The Use of Kosher Phenotyping for Mapping QTL Affecting Susceptibility to Bovine Respiratory Disease
Q34670501The Wnt/β-catenin pathway in human fibrotic-like diseases and its eligibility as a therapeutic target.
Q38131032The alarmin functions of high-mobility group box-1 and IL-33 in the pathogenesis of systemic lupus erythematosus.
Q33417978The association of lacrimal gland inflammation with alopecia areata
Q42911392The chemokine monocyte chemoattractant protein-1 contributes to renal dysfunction in swine renovascular hypertension
Q47152481The chemokines CXCL12 and CXCL14 differentially regulate connective tissue markers during limb development.
Q28386827The code of non-coding RNAs in lung fibrosis
Q35067772The development of nasal polyp disease involves early nasal mucosal inflammation and remodelling
Q39001100The different roles of myosin IIA and myosin IIB in contraction of 3D collagen matrices by human fibroblasts
Q92367121The double edge sword of fibrosis in cancer
Q39633175The effect of incorporation of SDF-1alpha into PLGA scaffolds on stem cell recruitment and the inflammatory response
Q35018345The effect of p38MAPK on cyclic stretch in human facial hypertrophic scar fibroblast differentiation
Q46157035The effect of sorafenib on hepatic stellate cells: implication of its effect on tumor microenvironment
Q37354744The effects of NOS2 gene deletion on mice expressing mutated human AbetaPP.
Q52589503The emerging role of fibrocytes in ocular disorders.
Q26783047The emerging roles of β-arrestins in fibrotic diseases
Q37409222The enigmatic cytokine oncostatin m and roles in disease
Q47803510The etiology of liver damage imparts cytokines transforming growth factor beta1 or interleukin-13 as driving forces in fibrogenesis
Q35601285The extracellular matrix: an active or passive player in fibrosis?
Q47205727The fibrotic tumor stroma
Q36193804The genetic pleiotropy of musculoskeletal aging.
Q36545542The herbal compound Songyou Yin (SYY) inhibits hepatocellular carcinoma growth and improves survival in models of chronic fibrosis via paracrine inhibition of activated hepatic stellate cells
Q35563973The immunological contribution to heterotopic ossification disorders
Q37682484The immunology of fibrosis: innate and adaptive responses
Q47652116The impact of SPARC on age-related cardiac dysfunction and fibrosis in Drosophila
Q38321523The importance of extracellular matrix for cell function and in vivo likeness.
Q50684000The inhibition effect and mechanism of SY0916 on pulmonary fibrosis.
Q37424208The interaction of Thrombospondins with extracellular matrix proteins
Q39421460The internal region leucine-rich repeat 6 of decorin interacts with low density lipoprotein receptor-related protein-1, modulates transforming growth factor (TGF)-β-dependent signaling, and inhibits TGF-β-dependent fibrotic response in skeletal musc
Q37427782The liaison between apoptotic cells and macrophages--the end programs the beginning.
Q24633454The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing
Q35780076The matricellular protein CCN1 mediates neutrophil efferocytosis in cutaneous wound healing
Q58115668The mechanisms and potential of stem cell therapy for penile fibrosis
Q38050078The microbiome in wound repair and tissue fibrosis
Q48364814The monocyte chemoattractant protein-1 (MCP-1)/CCR2 system is involved in peritoneal dialysis-related epithelial-mesenchymal transition of peritoneal mesothelial cells.
Q37733670The myofibroblast matrix: implications for tissue repair and fibrosis.
Q34106373The nucleic acid scavenger polyamidoamine third-generation dendrimer inhibits fibroblast activation and granulation tissue contraction
Q34994036The origin of fibroblasts and mechanism of cardiac fibrosis
Q37839779The origin of interstitial myofibroblasts in chronic kidney disease
Q40103784The orphan nuclear receptor RORα and group 3 innate lymphoid cells drive fibrosis in a mouse model of Crohn's disease
Q37800756The pathogenesis of idiopathic pulmonary fibrosis.
Q37040558The pathophysiology of epithelial-mesenchymal transition induced by transforming growth factor-beta in normal and malignant mammary epithelial cells
Q33354622The periprosthetic capsule and connective tissue diseases: a piece in the puzzle of autoimmune/autoinflammatory syndrome induced by adjuvants
Q48100107The pro-fibrotic connective tissue growth factor (CTGF/CCN2) correlates with the number of necrotic-regenerative foci in dystrophic muscle
Q34429947The promise of perfect adult tissue repair and regeneration in mammals: Learning from regenerative amphibians and fish.
Q89187517The regulatory role of interferon-γ producing gamma delta T cells via the suppression of T helper 17 cell activity in bleomycin-induced pulmonary fibrosis
Q37807765The role of Hedgehog signaling in fibrogenic liver repair
Q26796346The role of P2X7 receptors in tissue fibrosis: a brief review
Q39062904The role of TGF-β1 during skeletal muscle regeneration.
Q37955061The role of chronic inflammation in cutaneous fibrosis: fibroblast growth factor receptor deficiency in keratinocytes as an example
Q34061245The role of inflammatory and fibrogenic pathways in heart failure associated with aging.
Q37376157The role of iron in the pathogenesis of endometriosis
Q35046046The role of macrophage IL-10/innate IFN interplay during virus-induced asthma.
Q38024820The role of macrophages in healing the wounded lung
Q50458666The role of macrophages in the development of human renal allograft fibrosis in the first year after transplantation.
Q38246646The role of pericyte detachment in vascular rarefaction
Q38543690The role of the acquired immune response in systemic sclerosis
Q39117766The role of the extracellular matrix in primary myelofibrosis
Q37356743The role of transforming growth factor-beta-mediated tumor-stroma interactions in prostate cancer progression: an integrative approach
Q35654823The secretome of induced pluripotent stem cells reduces lung fibrosis in part by hepatocyte growth factor
Q36944484The significance of macrophage phenotype in cancer and biomaterials
Q46911221The therapeutic effects of bone marrow-derived mesenchymal stem cells and simvastatin in a rat model of liver fibrosis.
Q21559629The triterpenoid CDDO-Me inhibits bleomycin-induced lung inflammation and fibrosis
Q37800217The tumor microenvironment in hepatocellular carcinoma: current status and therapeutic targets.
Q38536374The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence
Q48159638The two faces of enhanced stroma: Stroma acts as a tumor promoter and a steric obstacle.
Q58783029The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis
Q27014616The wound healing, chronic fibrosis, and cancer progression triad
Q55289622Therapeutic Potential of Polyphenols in Cardiac Fibrosis.
Q37573815Therapeutic potential of endothelin receptor modulators: lessons from human clinical trials
Q35534899Therapies from fucoidan; multifunctional marine polymers
Q42502170Three distinct cell populations express extracellular matrix proteins and increase in number during skeletal muscle fibrosis
Q57177120Three-dimensional bioprinting of stem-cell derived tissues for human regenerative medicine
Q33499619Thrombospondin-2 therapy ameliorates experimental glomerulonephritis via inhibition of cell proliferation, inflammation, and TGF-beta activation
Q38660241Thy1 (CD90) Expression Is Elevated in Radiation-Induced Periprosthetic Capsular Contracture: Implication for Novel Therapeutics
Q27003231Tissue characterization of the myocardium: state of the art characterization by magnetic resonance and computed tomography imaging
Q34772841Tissue inhibitor of matrix-metalloprotease-1 predicts risk of hepatic fibrosis in human Schistosoma japonicum infection
Q36494364Tissue remodeling in eosinophilic esophagitis
Q50976924Tissue response to five commercially available peritoneal adhesion barriers-A systematic histological evaluation.
Q41973622Tissue-type plasminogen activator is not necessary for platelet-derived growth factor-c activation.
Q39226247Titanium dioxide nanoparticles induce matrix metalloprotease 1 in human pulmonary fibroblasts partly via an interleukin-1β-dependent mechanism.
Q38561820Toll-Like Receptors and Tissue Remodeling: The Pro/Cons Recent Findings.
Q42949359Toll-like receptor 9 activation is a key mechanism for the maintenance of chronic lung inflammation
Q37352820Toll-like receptors, wound healing, and carcinogenesis
Q91792926Topical Approach to Delivering Targeted Therapies in Lymphedema Treatment: A Systematic Review
Q42383547Toward an antifibrotic therapy for inflammatory bowel disease
Q37709748Towards a safe and effective chlamydial vaccine: lessons from the eye
Q34607259Trachoma: protective and pathogenic ocular immune responses to Chlamydia trachomatis
Q38028888Traditional Chinese medicine and immune regulation
Q94606276Transcriptome analysis identifies genes involved with the development of umbilical hernias in pigs
Q64235758Transcriptome network analysis identifies protective role of the LXR/SREBP-1c axis in murine pulmonary fibrosis
Q37642994Transcriptomics of post-stroke angiogenesis in the aged brain
Q37428739Transforming growth factor beta as a therapeutic target in systemic sclerosis
Q36072357Transforming growth factor-β neutralizing antibodies inhibit subretinal fibrosis in a mouse model
Q34408250Transforming growth factor-β1 induces matrix metalloproteinase-9 and cell migration in astrocytes: roles of ROS-dependent ERK- and JNK-NF-κB pathways
Q35527871Transglutaminase 2 and its role in pulmonary fibrosis.
Q33652543Translation of Angiotensin-Converting Enzyme 2 upon Liver- and Lung-Targeted Delivery of Optimized Chemically Modified mRNA
Q50198762Transplanting Human Skin Grafts onto Nude Mice to Model Skin Scars.
Q54062963Traumatic muscle fibrosis: From pathway to prevention.
Q37704966Treatment of Peyronie's disease with PDE5 inhibitors: an antifibrotic strategy
Q35545347Treatment of chronic kidney diseases with histone deacetylase inhibitors
Q54171744Treatment with Trichuris suis soluble products during monocyte-to-macrophage differentiation reduces inflammatory responses through epigenetic remodeling.
Q40926459Triazole RGD antagonist reverts TGFβ1-induced endothelial-to-mesenchymal transition in endothelial precursor cells.
Q37512338Trophic actions of bone marrow-derived mesenchymal stromal cells for muscle repair/regeneration
Q35461630Trps1 regulates biliary epithelial-mesenchymal transition and has roles during biliary fibrosis in liver grafts: a preliminary study
Q90355553Tryptophan metabolites kynurenine and serotonin regulate fibroblast activation and fibrosis
Q39325865Tubular Dickkopf-3 promotes the development of renal atrophy and fibrosis
Q37018721Tumor Necrosis Factor-Like Weak Inducer of Apoptosis Accelerates the Progression of Renal Fibrosis in Lupus Nephritis by Activating SMAD and p38 MAPK in TGF-β1 Signaling Pathway
Q37950602Tumor promotion via injury- and death-induced inflammation
Q39268764Tumor-associated fibrosis as a regulator of tumor immunity and response to immunotherapy.
Q38542046Two sides of one coin: massive hepatic necrosis and progenitor cell-mediated regeneration in acute liver failure
Q55241957Type 2 Immune Mechanisms in Carbon Nanotube-Induced Lung Fibrosis.
Q37439840Type-1 pericytes participate in fibrous tissue deposition in aged skeletal muscle
Q40293690Tyrosine kinase inhibitor BIBF1120 ameliorates inflammation, angiogenesis and fibrosis in CCl4-induced liver fibrogenesis mouse model.
Q41537028Ubiquitin C-terminal hydrolase 1: A novel functional marker for liver myofibroblasts and a therapeutic target in chronic liver disease
Q50071959Unbalanced Vitreous Levels of Osteoprotegerin, RANKL, RANK, and TRAIL in Proliferative Diabetic Retinopathy.
Q33631115Uncoupling of the profibrotic and hemostatic effects of thrombin in lung fibrosis
Q39143837Understanding the cellular basis and pathophysiology of Peyronie's disease to optimize treatment for erectile dysfunction
Q36930956Understanding the host response to cell-laden poly(ethylene glycol)-based hydrogels
Q39699112Understanding the process of fibrosis in Duchenne muscular dystrophy.
Q36673270Unraveling the signaling pathways promoting fibrosis in Dupuytren's disease reveals TNF as a therapeutic target
Q47131777Up-regulation of Interleukin-21 Contributes to Liver Pathology of Schistosomiasis by Driving GC Immune Responses and Activating HSCs in Mice
Q38183300Update on etiopathogenesis of systemic sclerosis
Q37777155Update on the pathophysiology of liver fibrosis
Q37196021Upregulation of RGS2: a new mechanism for pirfenidone amelioration of pulmonary fibrosis
Q81786197Upregulation of mRNA expression of MCP-1 by TGF-beta1 in fibroblast cells from Peyronie's disease
Q37711116Urinary collagen degradation products as early markers of progressive renal fibrosis
Q38837268Use of Xenopus Frogs to Study Renal Development/Repair
Q38850046Use of single chain antibody derivatives for targeted drug delivery
Q58806294VEGF Receptor-2 Activation Mediated by VEGF-E Limits Scar Tissue Formation Following Cutaneous Injury
Q95840792Vascular Signaling in Allogenic Solid Organ Transplantation - The Role of Endothelial Cells
Q37110345Vascular endothelium as a novel source of stem cells for bioengineering
Q36835180Vascular-targeted therapies for Duchenne muscular dystrophy
Q38149507Vein graft failure
Q33820772Ventral prostate fibrosis in the Akita mouse is associated with macrophage and fibrocyte infiltration
Q26770160View from the heart: cardiac fibroblasts in development, scarring and regeneration
Q36117933Vitamin D Attenuates Kidney Fibrosis via Reducing Fibroblast Expansion, Inflammation, and Epithelial Cell Apoptosis
Q24642477WISP1, a pro-mitogenic, pro-survival factor, mediates tumor necrosis factor-alpha (TNF-alpha)-stimulated cardiac fibroblast proliferation but inhibits TNF-alpha-induced cardiomyocyte death
Q42593075Welcome to fibrogenesis & tissue repair
Q36579608Wharton's jelly-derived mesenchymal stem cells combined with praziquantel as a potential therapy for Schistosoma mansoni-induced liver fibrosis
Q56981752Wilms' tumor 1 drives fibroproliferation and myofibroblast transformation in severe fibrotic lung disease
Q28482173Withaferin-A reduces type I collagen expression in vitro and inhibits development of myocardial fibrosis in vivo
Q38135328Wnt signaling in skeletal muscle dynamics: myogenesis, neuromuscular synapse and fibrosis
Q35044387Wound healing genes and susceptibility to cutaneous leishmaniasis in Brazil: role of COL1A1.
Q37591028Wound repair at a glance
Q38940635XL413, a cell division cycle 7 kinase inhibitor enhanced the anti-fibrotic effect of pirfenidone on TGF-β1-stimulated C3H10T1/2 cells via Smad2/4.
Q92132055Zi Shen Huo Luo Formula Enhances the Therapeutic Effects of Angiotensin-Converting Enzyme Inhibitors on Hypertensive Left Ventricular Hypertrophy by Interfering With Aldosterone Breakthrough and Affecting Caveolin-1/Mineralocorticoid Receptor Coloca
Q53624421[The epithelial-mesenchymal transition and fibrosis of the renal transplant].
Q101476490c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis
Q40803465iNOS Activity Modulates Inflammation, Angiogenesis, and Tissue Fibrosis in Polyether-Polyurethane Synthetic Implants
Q41955066iTRAQ-based proteomic profiling reveals different protein expression between normal skin and hypertrophic scar tissue
Q36108865miR-200c is aberrantly expressed in leiomyomas in an ethnic-dependent manner and targets ZEBs, VEGFA, TIMP2, and FBLN5.
Q35154821miR-200c regulates IL8 expression by targeting IKBKB: a potential mediator of inflammation in leiomyoma pathogenesis
Q38795098miR-21 promotes fibrosis in an acute cardiac allograft transplantation model.
Q35219800miR-29 is a major regulator of genes associated with pulmonary fibrosis.
Q36615791miR-9-5p suppresses pro-fibrogenic transformation of fibroblasts and prevents organ fibrosis by targeting NOX4 and TGFBR2
Q43434222microRNA alterations driving acute and late stages of radiation-induced fibrosis in a murine skin model
Q60045578microRNA-29b mediates fibrotic induction of human xylosyltransferase-I in human dermal fibroblasts via the Sp1 pathway
Q61443226sPIF promotes myoblast differentiation and utrophin expression while inhibiting fibrosis in Duchenne muscular dystrophy via the H19/miR-675/let-7 and miR-21 pathways
Q37629834uPA binding to PAI-1 induces corneal myofibroblast differentiation on vitronectin
Q47213785α-smooth muscle actin is not a marker of fibrogenic cell activity in skeletal muscle fibrosis.
Q37634132β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis

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