Enhanced protection from fibrosis and inflammation in the combined absence of IL-13 and IFN-γ

scientific article published on 29 April 2016

Enhanced protection from fibrosis and inflammation in the combined absence of IL-13 and IFN-γ is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/PATH.4733
P932PMC publication ID4915976
P698PubMed publication ID27125685

P50authorRichard L GieseckQ59702652
P2093author name stringThomas A Wynn
Allen W Cheever
Margaret M Mentink-Kane
Thirumalai R Ramalingam
Kevin M Hart
Kevin M Vannella
Thomas H Acciani
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Periportal fibrosis in human Schistosoma mansoni infection is associated with low IL-10, low IFN-gamma, high TNF-alpha, or low RANTES, depending on age and genderQ38882456
TH2 and TH17 inflammatory pathways are reciprocally regulated in asthma.Q41042964
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Simultaneous disruption of interleukin (IL)-4 and IL-13 defines individual roles in T helper cell type 2-mediated responsesQ42944667
IL-13 activates a mechanism of tissue fibrosis that is completely TGF-beta independentQ44007756
Schistosome infection of transgenic mice defines distinct and contrasting pathogenic roles for IL-4 and IL-13: IL-13 is a profibrotic agentQ44826352
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High levels of TNF, soluble TNF receptors, soluble ICAM-1, and IFN-gamma, but low levels of IL-5, are associated with hepatosplenic disease in human schistosomiasis mansoniQ58312856
An IL-12-based vaccination method for preventing fibrosis induced by schistosome infectionQ59054213
Cytokine Regulation of Periportal Fibrosis in Humans Infected with Schistosoma mansoni: IFN- Is Associated with Protection Against Fibrosis and TNF- with Aggravation of DiseaseQ63409796
Antagonistic regulation of type I collagen gene expression by interferon-gamma and transforming growth factor-beta. Integration at the level of p300/CBP transcriptional coactivatorsQ73336547
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IL-13 is a key regulatory cytokine for Th2 cell-mediated pulmonary granuloma formation and IgE responses induced by Schistosoma mansoni eggsQ77899629
Schistosome-infected IL-4 receptor knockout (KO) mice, in contrast to IL-4 KO mice, fail to develop granulomatous pathology while maintaining the same lymphokine expression profileQ77929251
P433issue3
P921main subjectinflammationQ101991
P304page(s)344-354
P577publication date2016-06-10
P1433published inJournal of PathologyQ400296
P1476titleEnhanced protection from fibrosis and inflammation in the combined absence of IL-13 and IFN-γ
P478volume239

Reverse relations

cites work (P2860)
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