| scholarly article | Q13442814 |
| P50 | author | Mary Collins | Q20084124 |
| Michael J Grusby | Q114438980 | ||
| P2093 | author name string | Thomas A Wynn | |
| Anthony Wong | |||
| Allen W Cheever | |||
| Mary E P Goad | |||
| Debra D Donaldson | |||
| Bruce A Jacobson | |||
| Monica G Chiaramonte | |||
| Margaret Mentink-Kane | |||
| Matthew J Whitters | |||
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| Schistosome-infected IL-4 receptor knockout (KO) mice, in contrast to IL-4 KO mice, fail to develop granulomatous pathology while maintaining the same lymphokine expression profile | Q77929251 | ||
| The IL-4 receptor: signaling mechanisms and biologic functions | Q28198739 | ||
| A novel mechanism by which interferon-gamma can regulate interleukin (IL)-13 responses. Evidence for intracellular stores of IL-13 receptor alpha -2 and their rapid mobilization by interferon-gamma | Q28215226 | ||
| Cloning and characterization of a specific interleukin (IL)-13 binding protein structurally related to the IL-5 receptor alpha chain | Q28281946 | ||
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| The role of IL-13 in helminth-induced inflammation and protective immunity against nematode infections. | Q33711407 | ||
| Chronic allograft rejection. Do the Th2 cells preferentially induced by indirect alloantigen recognition play a dominant role? | Q33748961 | ||
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| Anti-inflammatory cytokines | Q33892589 | ||
| Infection of mice lacking interleukin-7 (IL-7) reveals an unexpected role for IL-7 in the development of the parasite Schistosoma mansoni. | Q34001522 | ||
| Structure of and signal transduction through interleukin-4 and interleukin-13 receptors (review). | Q34483434 | ||
| Activation of hepatic stellate cells--a key issue in liver fibrosis | Q34565618 | ||
| The germless theory of allergic disease: revisiting the hygiene hypothesis. | Q34572144 | ||
| NOS-2 mediates the protective anti-inflammatory and antifibrotic effects of the Th1-inducing adjuvant, IL-12, in a Th2 model of granulomatous disease | Q35829420 | ||
| Recombinant human interleukin 5 is a selective activator of human eosinophil function | Q36354407 | ||
| Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology | Q36363125 | ||
| Enhanced interleukin (IL)-13 responses in mice lacking IL-13 receptor alpha 2. | Q36370592 | ||
| Strain-specific differences in mouse hepatic wound healing are mediated by divergent T helper cytokine responses | Q36591648 | ||
| Advanced multiplexed analysis with the FlowMetrix system | Q39453132 | ||
| IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis. | Q39461953 | ||
| IL-13-mediated worm expulsion is B7 independent and IFN-gamma sensitive | Q39533842 | ||
| Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13-induced inflammation and remodeling | Q39735936 | ||
| Cytokine regulation of granuloma formation in schistosomiasis | Q40380464 | ||
| Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production | Q40849898 | ||
| Requirement for IL-13 independently of IL-4 in experimental asthma | Q41881960 | ||
| Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1). | Q42101278 | ||
| Experimental production of bilharzial pipe-stem fibrosis in the chimpanzee | Q43616213 | ||
| Disease fingerprinting with cDNA microarrays reveals distinct gene expression profiles in lethal type 1 and type 2 cytokine-mediated inflammatory reactions. | Q43771291 | ||
| Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: granulomatous pathology is shaped by the pattern of L-arginine metabolism | Q43803694 | ||
| Effects of IL-13 on airway responses in the guinea pig. | Q43821604 | ||
| Tumour necrosis factor alpha restores granulomas and induces parasite egg-laying in schistosome-infected SCID mice | Q43868496 | ||
| Studies with double cytokine-deficient mice reveal that highly polarized Th1- and Th2-type cytokine and antibody responses contribute equally to vaccine-induced immunity to Schistosoma mansoni | Q44461357 | ||
| Schistosome infection of transgenic mice defines distinct and contrasting pathogenic roles for IL-4 and IL-13: IL-13 is a profibrotic agent | Q44826352 | ||
| Variation of hepatic fibrosis and granuloma size among mouse strains infected with Schistosoma mansoni | Q44970501 | ||
| The interleukin-4/interleukin-13 receptor of human synovial fibroblasts: overexpression of the nonsignaling interleukin-13 receptor alpha2. | Q48032045 | ||
| Studies of murine schistosomiasis reveal interleukin-13 blockade as a treatment for established and progressive liver fibrosis. | Q52543547 | ||
| Different cytokine profiles in cryptogenic fibrosing alveolitis and fibrosing alveolitis associated with systemic sclerosis: a quantitative study of open lung biopsies. | Q53923977 | ||
| A critical role for IL-13 in resistance to intestinal nematode infection. | Q54142884 | ||
| PCR analysis of cytokine induction profiles associated with mouse strain variation in susceptibility to pulmonary fibrosis. | Q54242299 | ||
| Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. | Q55066450 | ||
| Analysis of granuloma formation in double cytokine-deficient mice reveals a central role for IL-10 in polarizing both T helper cell 1- and T helper cell 2-type cytokine responses in vivo | Q57339964 | ||
| In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha | Q57339973 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 687-701 | |
| P577 | publication date | 2003-03-01 | |
| P1433 | published in | Journal of Experimental Medicine | Q3186912 |
| P1476 | title | Regulation and function of the interleukin 13 receptor alpha 2 during a T helper cell type 2-dominant immune response | |
| P478 | volume | 197 |
| Q37221291 | A novel and sensitive ELISA reveals that the soluble form of IL-13R-alpha2 is not expressed in plasma of healthy or asthmatic subjects |
| Q30585550 | A novel data mining system points out hidden relationships between immunological markers in multiple sclerosis. |
| Q36639999 | A role for sex chromosome complement in the female bias in autoimmune disease |
| Q33396838 | Accelerated and progressive and lethal liver fibrosis in mice that lack interleukin (IL)-10, IL-12p40, and IL-13Rα2. |
| Q92412689 | Allergen presensitization drives an eosinophil-dependent arrest in lung-specific helminth development |
| Q33804200 | Allergen-dependent solubilization of IL-13 receptor alpha2 reveals a novel mechanism to regulate allergy |
| Q91904006 | Anti-IL-13Rα2 therapy promotes recovery in a murine model of inflammatory bowel disease |
| Q33429032 | Arginase-1-expressing macrophages suppress Th2 cytokine-driven inflammation and fibrosis |
| Q34146893 | Association of type 2 cytokines with hepatic fibrosis in human Schistosoma mansoni infection |
| Q46904777 | Astragalus saponin attenuates the expression of fibrosis-related molecules in irradiated cardiac fibroblasts |
| Q34358339 | Blockade of transforming growth factor-beta1 accelerates lymphatic regeneration during wound repair |
| Q33325920 | Cationic amino acid transporter-2 regulates immunity by modulating arginase activity |
| Q24648892 | Cellular and molecular mechanisms of fibrosis |
| Q28248430 | Characterization of the interaction between interleukin-13 and interleukin-13 receptors |
| Q37705711 | Chitinase 3-like 1 regulates cellular and tissue responses via IL-13 receptor α2 |
| Q36040475 | Chitinase 3-like-1 and its receptors in Hermansky-Pudlak syndrome-associated lung disease |
| Q41818218 | Commentary: IL-4 and IL-13 receptors and signaling |
| Q35649473 | Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases |
| Q40044922 | Comparative Study of Transcriptome Profiles of Mouse Livers and Skins Infected by Fork-Tailed or Non-Fork-Tailed Schistosoma japonicum |
| Q33778585 | Coxiella burnetii, the agent of Q fever, replicates within trophoblasts and induces a unique transcriptional response |
| Q37209512 | Cytokine mediated tissue fibrosis |
| Q34334214 | Cytokine production associated with periportal fibrosis during chronic schistosomiasis mansoni in humans |
| Q35603986 | Cytokine regulation in experimentally-induced Schistosoma japonicum egg granuloma formation |
| Q36905414 | Cytokines mediating the induction of chronic colitis and colitis-associated fibrosis |
| Q42944812 | Decoy receptors in the regulation of T helper cell type 2 responses |
| Q27313373 | Deficiency in Th2 cytokine responses exacerbate orthopoxvirus infection |
| Q37689006 | Differential effects of peptidoglycan on colorectal tumors and intestinal tissue post-pelvic radiotherapy |
| Q33263474 | Differential liver protein expression during schistosomiasis |
| Q36660614 | Distinct roles for IL-13 and IL-4 via IL-13 receptor alpha1 and the type II IL-4 receptor in asthma pathogenesis |
| Q36687542 | Emerging functions of amphiregulin in orchestrating immunity, inflammation, and tissue repair. |
| Q36370592 | Enhanced interleukin (IL)-13 responses in mice lacking IL-13 receptor alpha 2. |
| Q37026406 | Enhanced protection from fibrosis and inflammation in the combined absence of IL-13 and IFN-γ |
| Q35606790 | Extracellular and intracellular decoys in the tuning of inflammatory cytokines and Toll-like receptors: the new entry TIR8/SIGIRR. |
| Q64954227 | Fibroproliferative genes are preferentially expressed in central centrifugal cicatricial alopecia. |
| Q35852270 | Fibrotic disease and the T(H)1/T(H)2 paradigm |
| Q36765830 | Functional importance of regional differences in localized gene expression of receptors for IL-13 in murine gut. |
| Q34102567 | Gene profiling of keloid fibroblasts shows altered expression in multiple fibrosis-associated pathways. |
| Q35035593 | Glioma IL13Rα2 is associated with mesenchymal signature gene expression and poor patient prognosis |
| Q38615196 | Host regulation of liver fibroproliferative pathology during experimental schistosomiasis via interleukin-4 receptor alpha |
| Q26852800 | Host responses in tissue repair and fibrosis |
| Q80336048 | Human schistosomiasis mansoni: intensity of infection differentially affects the production of interleukin-10, interferon-gamma and interleukin-13 by soluble egg antigen or adult worm antigen stimulated cultures |
| Q38010706 | IL-13 Signaling in Liver Fibrogenesis |
| Q37526117 | IL-13 is a therapeutic target in radiation lung injury. |
| Q24597767 | IL-13 receptor alpha 2 down-modulates granulomatous inflammation and prolongs host survival in schistosomiasis |
| Q33479866 | IL-13 receptor alpha2 regulates the immune and functional response to Nippostrongylus brasiliensis infection |
| Q36909673 | IL-13 receptor isoforms: breaking through the complexity |
| Q38003478 | IL-13 receptor-directed cancer vaccines and immunotherapy |
| Q39486476 | IL-13 regulates cancer invasion and metastasis through IL-13Rα2 via ERK/AP-1 pathway in mouse model of human ovarian cancer |
| Q28285105 | IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis |
| Q37641580 | IL-13/STAT6 signaling plays a critical role in the epithelial-mesenchymal transition of colorectal cancer cells |
| Q33654576 | IL-13R alpha 2 membrane and soluble isoforms differ in humans and mice |
| Q35995705 | IL-13Ralpha2 and IL-10 coordinately suppress airway inflammation, airway-hyperreactivity, and fibrosis in mice |
| Q34610797 | IL-13Rα2 has a protective role in a mouse model of cutaneous inflammation |
| Q37264739 | IL-13Rα2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses |
| Q38758144 | IL-17A enhances IL-13 activity by enhancing IL-13-induced signal transducer and activator of transcription 6 activation |
| Q52717941 | IL13Rα2 expression identifies tissue-resident IL-22 producing PLZF+ innate T cells in the human liver. |
| Q38826634 | Immune Mechanisms in Pulmonary Fibrosis |
| Q28204460 | Immune regulation by helminth parasites: cellular and molecular mechanisms |
| Q43568745 | Immunomodulatory effect of R848 on cytokine production associated with Schistosoma mansoni infection |
| Q35884223 | Immunopathogenesis of schistosomiasis |
| Q36220509 | Immunopathology of schistosomiasis |
| Q34003580 | Importance of cytokines in murine allergic airway disease and human asthma |
| Q34166520 | Incomplete deletion of IL-4Rα by LysM(Cre) reveals distinct subsets of M2 macrophages controlling inflammation and fibrosis in chronic schistosomiasis. |
| Q35106452 | Integrating mechanisms of pulmonary fibrosis |
| Q37582805 | Interleukin-10 (IL-10) counterregulates IL-4-dependent effector mechanisms in Murine Filariasis |
| Q34787194 | Interleukin-13 (IL-13)/IL-13 receptor alpha1 (IL-13Ralpha1) signaling regulates intestinal epithelial cystic fibrosis transmembrane conductance regulator channel-dependent Cl- secretion. |
| Q34534282 | Interleukin-13 Activates Distinct Cellular Pathways Leading to Ductular Reaction, Steatosis, and Fibrosis |
| Q38197617 | Interleukin-13 and its receptors in colorectal cancer (Review). |
| Q37284666 | Interleukin-13 and its receptors in idiopathic interstitial pneumonia: clinical implications for lung function |
| Q92668477 | Interleukin-13 disrupts type 2 pneumocyte stem cell activity |
| Q35652268 | Interleukin-13 in asthma pathogenesis |
| Q28281586 | Interleukin-13 in the skin and interferon-gamma in the liver are key players in immune protection in human schistosomiasis |
| Q35644889 | Interleukin-13: a key mediator in resistance to gastrointestinal-dwelling nematode parasites |
| Q57147435 | Involvement of Hookworm Co-Infection in the Pathogenesis and Progression of Podoconiosis: Possible Immunological Mechanism |
| Q37137670 | Lysophosphatidic acid induces interleukin-13 (IL-13) receptor alpha2 expression and inhibits IL-13 signaling in primary human bronchial epithelial cells |
| Q37139302 | Lysophosphatidic acid signaling in airway epithelium: role in airway inflammation and remodeling |
| Q42187121 | MAPK regulation of IL-4/IL-13 receptors contributes to the synergistic increase in CCL11/eotaxin-1 in response to TGF-β1 and IL-13 in human airway fibroblasts |
| Q36128289 | Macrophage activation governs schistosomiasis-induced inflammation and fibrosis |
| Q26774652 | Macrophage and Innate Lymphoid Cell Interplay in the Genesis of Fibrosis |
| Q29614349 | Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm |
| Q37163250 | Matrix metalloproteinase 8 contributes to solubilization of IL-13 receptor alpha2 in vivo |
| Q90031809 | Mechanisms of Dupilumab |
| Q29620307 | Mechanisms of fibrosis: therapeutic translation for fibrotic disease |
| Q34794616 | MicroRNA-gene expression network in murine liver during Schistosoma japonicum infection |
| Q33731233 | Modulation of exaggerated-IgE allergic responses by gene transfer-mediated antagonism of IL-13 and IL-17e |
| Q27660192 | Molecular Basis for Shared Cytokine Recognition Revealed in the Structure of an Unusually High Affinity Complex between IL-13 and IL-13Rα2 |
| Q37686798 | Monocyte subsets in schistosomiasis patients with periportal fibrosis |
| Q39084322 | Negative Regulation of Type 2 Immunity |
| Q34123969 | Negative regulation of Schistosoma japonicum egg-induced liver fibrosis by natural killer cells |
| Q37174214 | On the hunt for helminths: innate immune cells in the recognition and response to helminth parasites |
| Q35951827 | Opposing roles for IL-13 and IL-13 receptor alpha 2 in health and disease |
| Q44785863 | P-selectin suppresses hepatic inflammation and fibrosis in mice by regulating interferon gamma and the IL-13 decoy receptor |
| Q43096273 | Paeoniflorin ameliorates schistosomiasis liver fibrosis through regulating IL-13 and its signalling molecules in mice |
| Q26779081 | Pleiotropic Effects of Immune Responses Explain Variation in the Prevalence of Fibroproliferative Diseases |
| Q40485925 | Receptor Antagonist of IL-13 Exerts a Potential Negative Regulation During Early Infection of Human Schistosomiasis |
| Q35644885 | Regulation of allergy and autoimmunity in helminth infection |
| Q93160952 | Regulatory T cells in skin are uniquely poised to suppress profibrotic immune responses |
| Q37353748 | Restoration of tumor immunosurveillance via targeting of interleukin-13 receptor-alpha 2. |
| Q34360300 | Role of interleukin-13 in fibrosis, particularly systemic sclerosis |
| Q59127674 | Schistosoma "Eggs-Iting" the Host: Granuloma Formation and Egg Excretion |
| Q27006491 | Schistosomiasis-associated pulmonary hypertension |
| Q34087045 | Schistosomiasis-induced experimental pulmonary hypertension: role of interleukin-13 signaling |
| Q89110163 | Serum level of interleukin-13 receptor alpha 2 in infants with biliary atresia - is it of value? |
| Q39539596 | Silencing IL-13Rα2 promotes glioblastoma cell death via endogenous signaling |
| Q33622760 | Silymarin reduces profibrogenic cytokines and reverses hepatic fibrosis in chronic murine schistosomiasis. |
| Q36296731 | Site-specific gene expression profiling as a novel strategy for unravelling keloid disease pathobiology |
| Q36403704 | Suppression of allergic airway inflammation by helminth-induced regulatory T cells |
| Q35084474 | Systemic effector and regulatory immune responses to chlamydial antigens in trachomatous trichiasis |
| Q33799732 | Targeting interleukin-13 with tralokinumab attenuates lung fibrosis and epithelial damage in a humanized SCID idiopathic pulmonary fibrosis model. |
| Q92142275 | Th2 CD4+ T Cells Are Necessary and Sufficient for Schistosoma-Pulmonary Hypertension |
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| Q35484899 | Th2 signals induce epithelial injury in mice and are compatible with the biliary atresia phenotype |
| Q36272421 | The Causal Role of IL-4 and IL-13 in Schistosoma mansoni Pulmonary Hypertension. |
| Q40048581 | The Diacylglycerol-dependent translocation of ras guanine nucleotide-releasing protein 4 inside a human mast cell line results in substantial phenotypic changes, including expression of interleukin 13 receptor alpha2. |
| Q34682153 | The IL-21 receptor augments Th2 effector function and alternative macrophage activation |
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